Verfügbarkeit: Pediatric critical care

Pediatric critical care:

Gespeichert in:

Bibliographische Detailangaben
Format:	Buch
Sprache:	English
Veröffentlicht:	St. Louis [u.a.] Mosby 1998
Ausgabe:	2. ed.
Schlagworte:	Intensive care Kinderen Kind Child Critical Care Infant Pediatric intensive care
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	Literaturangaben
Beschreibung:	XXXII, 1438 S. Ill., graph. Darst.
ISBN:	0815125364

Internformat

MARC


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245	1	0	\|a Pediatric critical care \|c Bradley P. Fuhrman ; Jerry J. Zimmerman
250			\|a 2. ed.
264		1	\|a St. Louis [u.a.] \|b Mosby \|c 1998
300			\|a XXXII, 1438 S. \|b Ill., graph. Darst.
336			\|b txt \|2 rdacontent
337			\|b n \|2 rdamedia
338			\|b nc \|2 rdacarrier
500			\|a Literaturangaben
650		7	\|a Intensive care \|2 gtt
650		7	\|a Kinderen \|2 gtt
650		4	\|a Kind
650		4	\|a Child
650		4	\|a Critical Care
650		4	\|a Infant
650		4	\|a Pediatric intensive care
700	1		\|a Fuhrman, Bradley P. \|e Sonstige \|4 oth
700	1		\|a Zimmerman, Jerry J. \|e Sonstige \|4 oth
856	4	2	\|m HBZ Datenaustausch \|q application/pdf \|u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008082093&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA \|3 Inhaltsverzeichnis
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Datensatz im Suchindex

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adam_text	CONTENTS PART I The Patient and the Discipline 1 THE PEDIATRIC CRITICAL CARE PATIENT, 1 Jerry J. Zimmerman 2 WHAT IS A PEDIATRIC INTENSIVIST? 6 Bradley P. Fuhrman The Pediatric Intensivist and the PICU, 6 The Pediatric Intensivist as the Answer, 7 3 ETHICS IN PEDIATRIC INTENSIVE CARE, 8 Joel E. Frader Moral Theory, 8 Surrogate Decision Making: Parental Rights and Obligations, 12 The Pediatric ICU and Experimentation, 15 4 MALPRACTICE AND OTHER SORROWS, 18 Ellen Wright Clayton Malpractice, 18 Confidentiality, 21 Organizational Concerns within the Hospital, 23 Efforts by the Courts to Reduce their Involvement in the Intensive Care Unit, 23 5 SOCIOECONOMICS OF PEDIATRIC CRITICAL CARE, 25 Thomas A. Massaro Socioeconomic Status and Health Risk, 25 US Health Care System, 26 Physician Resources, 29 PICU Resources, 30 Summary, 30 6 ETHICAL ISSUES IN DEATH AND DYING, 32 Norman Post Withholding and Withdrawing Life Support, 32 Definition of Death and Organ Retrieval, 36 7 THE FAMILY IS THE PATIENT, 38 Stephen M. Schexnayder, Patricia H.I. Bryant, Debra H. Fiser Coping, 38 Interventions, 38 Hostility, 39 The Dying Child, 40 Long Term Impact of Crisis on the Family, 41 Impact of Stress on the PICU Staff, 41 8 NONACCIDENTAL INJURY, 43 David L. Chadwick, Bradley M. Peterson Overview and Approach to the Problem, 43 Reports and Testimony, 47 9 HISTORY OF PEDIATRIC INTENSIVE CARE IN THE UNITED STATES, 49 Lucian K. DeNicola, I. David Todres Summary, 52 10 ISSUES IN UNIT MANAGEMENT AND DESIGN, 54 Timothy S. Yeh Characteristics of PICU Capabilities—System Development, 54 The Pediatric Intensive Care Unit, 56 PICU Organization, 57 Summary, 60 11 PEDIATRIC TRANSPORT, 62 Richard A. Orr, Karin A. McCloskey, Shekhar T. Venkataraman Interhospital Transport, 62 Intrahospital Transport, 67 Conclusion, 68 12 INVASIVE MEASUREMENTS EM THE PICU, 70 William H. Perloff Role of Invasive Measurements, 70 Hemodynamic Monitoring, 70 Invasive Hemodynamic Monitoring Techniques, 81 Monitoring Respiratory Mechanics, 86 Intracranial Dynamics Monitoring, 89 Comment, 91 13 NONINVASIVE VITAL MONITORING IN CHILDREN, 95 Michael F. Sweeney, Melanie S. Madsen, Kumar G. Belani, David B. Swedlow Pulse Oximetry, 95 Capnometry and Capnography, 98 Temperature Monitoring and Routine Temperature Management, 101 Noninvasive Blood Pressure Measurement (NIBP), 103 Conclusion, 104 14 PEDIATRIC AIRWAY MANAGEMENT, 106 Ann E. Thompson Anatomical Considerations, 106 Basic Airway Management, 106 Endotracheal Intubation, 109 Special Circumstances, 117 Alternative Airways, 121 15 PEDIATRIC VASCULAR ACCESS, 126 Richard H. Strauss Epidemiology, 126 Physics of Flow Through a Tube, 126 Types of Vascular Access Devices, 126 Routes of Vascular Access, 129 16 DIAGNOSTIC AND THERAPEUTIC CENTESES, 140 Thomas B. Rice, Stephen P. Pontus, Jr. Pericardiocentesis, 140 Thoracentesis, 143 Abdominal Paracentesis, 147 17 PREDICTION OF OUTCOME, 152 Murray M. Pollack Development and Validation of Clinical Scores, 152 Intensive Care Uses of Scoring Systems, 154 18 RESEARCH IN PEDIATRIC CRITICAL CARE, 162 Randall C. Wetzel Research Areas, 162 The Wellsprings of Research, 163 Doing Research, 166 Medical Research, 169 Statistics: A Word, 172 Research Funding, 175 Ethics in Research, 182 19 THE NURSE IN PEDIATRIC CRITICAL CARE, 187 Mary Fran Hazinski Nurse Recruitment, 187 Staff Nurse Orientation, 187 Staff Nurse Retention, 193 Interdisciplinary Collaboration, Staff Development, and Quality of Care, 194 Nursing Leadership, 196 Summary, 197 PART II Organ System Function and Failure Section A Circulation 20 STRUCTURE AND FUNCTION OF THE HEART, 200 Julien I.E. Hoffman Contents xxiii Anatomical Development and Structure, 200 Physiological Development and Function, 202 21 STRUCTURE AND FUNCTION OF THE REGIONAL VASCULATURE, 222 Bradley P. Fuhrrnan Collective Characteristics of the Peripheral Vasculature, 222 Common Characteristics of the Peripheral Vasculature, 225 Local Regulation of the Circulation, 225 Pulmonary Circulation, 226 Cerebral Circulation, 228 Coronary Circulation, 230 Intestinal Circulation, 231 Conflicting Needs of Regional Circulations, 232 22 OXYGEN DEMAND, DELIVERY, AND CONSUMPTION, 235 John T. Fahey, George Lister Determinants of O2 Supply, 235 Determinants of O2 Demands, 236 Response to Inadequate Do2, 238 Estimating Adequacy of O2 Delivery, 240 Current Controversies, 244 Therapeutic Implications and Clinical Usefulness, 246 Summary, 247 23 CARDIOPULMONARY INTERACTIONS, 250 Adelaida M. Miro, Michael R. Pinsky Effects of Respiration on Cardiovascular Function, 250 Effects of Cardiovascular Function on Respiration, 253 Clinical Applications, 254 Summary, 259 24 DISORDERS OF THE CIRCULATION: MYOCARDIAL DYSFUNCTION, 261 Thomas P. Graham, Jr. Basic Concepts of Ventricular Function, 261 Basic Concepts of Diastolic Ventricular Function, 263 Assessment of Ventricular Function, 265 Treatment of Myocardial Dysfunction, 268 Summary, 270 25 DISORDERS OF CARDIAC RHYTHM, 272 Frank A. Fish, D. Woodrow Benson, Jr. Classification of Dysrhythmias, 272 Approach to Diagnosis, 276 Treatment of Rhythm Disturbances, 279 Specific Dysrhythmias, 286 26 SHOCK STATES, 293 Mark S. McConnell, Ronald M. Perkin Definition and Physiology, 293 Recognition and Assessment of the Shock State, 294 Treatment of Shock, 294 xxiv Contents Multisystem Effects of Shock, 295 Functional Classification and Common Underlying Etiologies, 296 Hypovolemic Shock, 296 Cardiogenic Shock or Congestive Heart Failure, 298 Obstructive Shock, 301 Distributive Shock, 302 Septic Shock, 302 27 INFECTION OF THE HEART AND PERICARDIUM, 307 Michael D. Green, Edward L. Kaplan Endocarditis, 307 Bacterial Infection of the Pericardium, 311 Bacterial Infection of the Myocardium, 312 Viral Myocarditis, 312 28 HYPERTENSION IN THE PICU, 314 Denise M. Goodman, Thomas P. Green Definition of Terms, 314 Pathophysiology, 314 Measurement of Blood Pressure, 317 Evaluation, 317 Management, 318 Summary, 321 29 ASSESSMENT AND MONITORING OF CARDIOVASCULAR FUNCTION, 323 Jon N. Meliones, Jennifer Li Determinants of Ventricular Function, 323 Methods of Assessing and Monitoring Cardiovascular Function, 324 30 PHARMACOLOGY OF THE CARDIOVASCULAR SYSTEM, 329 Daniel A. Notterman Mechanisms of Response, 329 Sympathomimetic Amines, 331 Bipyradines, 342 Digitalis Glycosides, 343 Conclusion, 345 31 CARDIOPULMONARY BYPASS FOR REPAIR OF CONGENITAL HEART DISEASE IN INFANTS AND CHILDREN, 347 John E. Mayer, Jr. Principles and Mechanics of Cardiopulmonary Bypass, 347 Myocardial Protection, 351 32 CRITICAL CARE AFTER SURGERY FOR CONGENITAL CARDIAC DISEASE, 354 Michele C. Papo, Eliot R. Rosenkranz, Lynn J. Hernan, Bradley P. Fuhrman Surgical Treatment of Congenital Heart Defects, 354 Common Complications of Operations for CHD, 360 Issues in Critical Care After Pediatric Cardiac Operations, 362 33 ECHOCARDIOGRAPHY, 371 Joseph D. One, Daniel R. Pieroni, Jean Michel A. Roland, Robert L. Gingell Principles of Echocardiography, 371 Echocardiography in the ICU Setting, 372 Conclusions, 375 Section B Respiration 34 STRUCTURE OF THE RESPIRATORY SYSTEM, 377 Jacqueline J. Coalson Upper Respiratory System, 377 Lower Respiratory System, 379 Pulmonary Circulation, 383 Pulmonary Lymphatics, 384 Diaphragm, 385 35 FUNCTION AND PHYSIOLOGY OF THE RESPIRATORY SYSTEM, 386 Robert Katz Upper Airway, 386 Lung, 387 Pulmonary Circulation, 393 Mechanics of Breathing, 393 Dynamic Properties of the Lung, 394 Distribution of Ventilation, 395 Control of Breathing, 395 Immune Function in the Lung, 397 Metabolic Function of the Vascular Endothelium, 398 36 VENTILATION PERFUSION INEQUALITY, 400 Howard Eigen, Jeffrey Macke General Principles of V: Q Inequality, 400 Clinical Measures of V: Q Inequality, 402 Pulmonary Pathology and V:Q Inequality, 403 Therapeutic Considerations, 407 37 MECHANICAL DYSFUNCTION OF THE RESPIRATORY SYSTEM, 409 J. Julio Perez Fontdn Energy Expenditure in the Respiratory System, 409 Determinants of Respiratory Work, 409 Determinants of Respiratory Efficiency, 417 Conclusion, 420 38 ASSESSMENT AND MONITORING OF RESPIRATORY FUNCTION, 422 Harris P. Baden, P. Pearl O Rourke Physical Examination, 422 Radiography, 422 Evaluation of Gas Exchange, 423 Shunt, 424 Dead Space Ventilation: Estimation of Dead Space, 425 Pulmonary Function Tests, 426 Endoscopy, 427 Summary, 427 39 SPECIFIC DISEASES OF THE RESPIRATORY SYSTEM: UPPER AIRWAY, 429 David Jardine Initial Management, 429 Congenital Malformations, 430 Infectious Processes, 432 Trauma, 436 Angioedema, 438 Tracheostomy, 439 40 SPECIFIC DISEASES OF THE RESPIRATORY SYSTEM: NEONATAL RESPIRATORY DISEASE, 442 James J. Cummings Acute or Early Onset Respiratory Disorders, 442 Congenital Malformations of the Lung, 445 New Treatment Modalities for Acute Respiratory Failure, 449 Chronic Pulmonary Disease, 450 Nonpulmonary Conditions that Result in Respiratory Disease, 452 41 PULMONARY EDEMA AND ARDS, 457 James A. Royall Fluid Flux in the Lung, 457 Permeability (Noncardiogenic) Pulmonary Edema and ARDS, 459 Special Causes of Pulmonary Edema, 468 42 LOWER AIRWAY DISEASE, 472 Veda L. Ackerman, Howard Eigen Malformations of the Lower Airway, 472 Bronchospastic Disorders, 473 43 PHARMACOLOGY OF THE RESPIRATORY SYSTEM, 477 Veda L. Ackerman, Dennis Gardner Apnea, 477 Respiratory Muscle Pharmacotherapy, 478 Laryngotracheobronchitis, 478 Acute Asthma, 479 Bronchiolitis, 481 Bronchopulmonary Dysplasia, 482 Acute Lung Injury, 482 44 PNEUMONITIS AND INTERSTITIAL DISEASE, 485 Thomas B. Rice, Stephen P. Pontus, Jr. Pathogenesis, 485 Pathophysiology, 485 Diagnosis, 486 Laboratory Diagnosis, 486 Bacterial Pneumonitis, 486 Viral Pneumonitis, 489 Fungal Pneumonitis, 494 Primary Pulmonary Fungi, 494 Opportunistic Pulmonary Mycoses, 497 Pneumocystis Carinii Pneumonia, 498 Chemical Pneumonitis, 500 Contents xxv Idiopathic Interstitial Lung Disease, 503 Pediatric Pulmonary Hemorrhage, 503 Summary, 507 45 DISEASES OF PULMONARY CIRCULATION, 512 Sandra Suchomski, Frederick C. Morin, HI Pulmonary Vasculature Development: Anatomical, 512 Pulmonary Vasculature Development: Functional, 514 Transition at Birth, 515 Etiologies of Persistent Pulmonary Hypertension in the Newborn, 517 Diagnosis of PPHN, 519 Management of PPHN, 519 Pulmonary Vascular Disease After the Immediate Newborn Period, 521 Pulmonary Vasodilation After the Immediate Newborn Period, 523 Pulmonary Hypertension in Association with Congenital Heart Disease, 524 Summary, 525 46 CONTROL OF BREATHING AND ACUTE RESPIRATORY FAILURE, 529 Robert K. Kanter Normal Regulation of Breathing, 529 Factors Impairing Respiratory Controls, 530 Controls of Breathing in Advanced Respiratory Failure, 534 Implications for Patient Management, 535 47 MECHANICAL VENTILATION AND RESPIRATORY CARE, 538 Shekhar T. Venkataraman, Richard A. Orr Applied Respiratory Physiology, 538 Indications for Mechanical Ventilation, 539 Design and Functional Characteristics of Mechanical Positive Pressure Ventilators, 540 Modes of Ventilation, 542 CPAP/PEEP, 544 Selection of Parameters During Mechanical Ventilation, 545 Approach to Mechanical Ventilation Based on Underlying Pathophysiology, 546 Special Techniques of Respiratory Support, 548 Noninvasive Mechanical Ventilation, 548 Airway Pressure Release Ventilation, 549 High Frequency Ventilation, 549 Adverse Effects of Mechanical Ventilation, 552 Effects on Circulatory System, 553 Respiratory Care During Mechanical Ventilation, 553 Weaning from Mechanical Ventilation. 555 Discontinuing Mechanical Ventilation, 557 Home Respiratory Care, 557 Summary, 558 48 EXTRACORPOREAL MEMBRANE OXYGENATION, 562 Heidi J. Dalton, Ann E. Thompson ECMO Circuit, 562 xxvi Contents Membrane Oxygenator, 564 Oxygen Delivery with ECMO, 565 Modes of Extracorporeal Support, 566 Disease States Treated with ECMO, 566 Patient Selection Criteria, 568 Patient Management, 569 Complications and Concerns, 571 Outcome, 571 ECMO Use in Myocardial Dysfunction, 572 Summary, 573 49 PERFLUOROCARBON LIQUID VENTILATION, 576 Bradley P. Fuhrman, Lynn J. Hernan, Michele C. Papo, David M. Steinhorn Liquid Breathing, 576 Tidal Liquid Ventilation (TLV), 576 Partial Liquid Ventilation and Perfluorocarbon Associated Gas Exchange, 577 Partial Liquid Ventilation in Models of Lung Disease, 578 Antiinflammatory Effects of Perflubron, 579 Surfactant Production, 580 Management of Secretions, 580 Partial Liquid Ventilation as a Means of Drug Delivery, 580 Combining New Therapies, 580 Clinical Trials of PLV with LiquiVent (Perflubron), 581 Section C CNS and Neuromuscular 50 DEVELOPMENT, STRUCTURE, AND FUNCTION OF THE BRAIN AND NEUROMUSCULAR SYSTEMS, 583 Michael V. Johnston Cellular Development, 583 Anatomical Development, 588 Clinical Correlates of Postnatal Neuromuscular Development, 590 Anatomical Localization: Physiology and Function, 591 51 PEDIATRIC NEUROLOGICAL ASSESSMENT AND MONITORING, 595 Giilay Pinar Alper, Ira Bergman Observation, 595 Level of Consciousness and Mental Status, 596 General Neurological Examination, 597 Psychogenic Coma, 600 Sedation and Paralysis, 600 Laboratory Adjuncts, 600 CSF, 601 Brain Death, 605 52 INTRACRANIAL HYPERTENSION, 607 W. Bradley Poss, S. David Moss, J. Michael Dean Physiology of the Intracranial Vault, 607 Purposes of Monitoring Intracranial Pressure, 608 Intracranial Pressure Monitoring Devices, 608 Intracranial Pressure Waveform Analysis, 612 Complications of Intracranial Pressure Monitoring, 614 Treatments of Intracranial Hypertension, 615 Reduction of Intracranial Volume, 615 Does Intracranial Pressure Monitoring Affect Outcome?, 616 Summary, 616 53 COMA IN THE PEDIATRIC PATIENT, 618 Curt M. Steinhart, Anthony L. Pearson Shaver Levels of Coma, 618 Anatomical Causes of Coma and Their Physiological Consequences, 618 Mass Lesions, 619 Causes of Coma and Their Manifestations, 620 Diagnostic Evaluation, 621 Imaging Modalities, 623 Therapeutic Strategies, 623 Outcome, 623 54 DIAGNOSIS AND TREATMENT OF STATUS EPILEPTICUS, 625 James P. Orlowski, A. David Rothner Generalized Tonic Clonic or Major Motor Status Epilepticus, 625 Physiological Changes During Convulsive Status Epilepticus, 625 Pathophysiology of Status Epilepticus, 628 Neonatal Status Epilepticus, 628 Management, 628 Recommended Protocol for Status Epilepticus, 631 Newer Agents for Status Epilepticus, 631 Induced Electrocerebral Silence for Refractory Status Epilepticus, 632 Diagnosing the Cause of Status Epilepticus, 632 Metabolic Causes of Status Epilepticus and Their Treatment, 634 Febrile Status Epilepticus, 634 Conclusion, 634 55 ACUTE NEUROMUSCULAR DISEASES AND DISORDERS IN PEDIATRIC CRITICAL CARE, 636 Robert L. Sufit Disorders Located Primarily Within the Motor Neuron, 636 Diseases and Disorders that Affect the Peripheral Nerves, 637 Diseases of the Neuromuscular Junction, 639 Diseases of Muscle, 641 Muscle Disorders in Other Contexts, 642 Summary, 643 56 ACUTE PEDIATRIC CENTRAL NERVOUS SYSTEM INFECTIONS, 645 Jeffrey S. Rubenstein Bacterial Meningitis, 645 Viral Meningoencephalitis or Encephalitis, 650 Viral Meningitis, 652 57 NEUROSURGICAL INTENSIVE CARE: SELECTED ASPECTS, 654 Stephen R. Guertin Cerebral Vascular Disease, 654 Brain Tumors: Selected Aspects, 661 CSF Shunts, 665 58 HYPOXIC ISCHEMIC ENCEPHALOPATHY: PATHOBIOLOGY AND THERAPY OF THE POSTRESUSCITATION SYNDROME IN CHILDREN, 671 Patrick M. Kochanek, Mark W. Uhl, Rebecca J. Schoettle, Laurence Katz, Robert S.B. Clark, Peter Safar Mechanisms of Hypoxic Ischemic Brain Injury, 672 Cellular and Molecular Pathobiology, 672 Clinical Pathophysiology, 678 Treatment of Cardiopulmonary Arrest, 683 Summary, 687 Section D Renal 59 AN OVERVIEW OF RENAL STRUCTURE AND FUNCTION, 692 Andrew S. Brem Overview of Structure, 692 Physiological Principles, 695 Tubular Function, 697 Hormone Effects, 699 60 FLUID AND ELECTROLYTE BALANCE, 703 Ellen G. Wood, Robert E. Lynch Water Spaces, 703 Water Balance, 703 Sodium, 703 Potassium, 709 Magnesium, 714 Phosphorus, 716 61 ACID BASE BALANCE AND DISORDERS, 723 Larry S. Jefferson, J. Timothy Bricker Acid Base Homeostasis, 723 Acid Base Disorders, 724 Therapy, 728 62 FUNCTIONAL TESTS OF THE KIDNEY IN HEALTH AND DISEASE, 732 Michael C. Chobanian Measurement of Glomerular Filtration Rate and the Glomerular Barrier, 732 Measurements of Salt and Water Homeostasis, 733 Measurement of Acid Base Parameters, 734 Measurement of Other Tubular Functions, 736 Assessment of the Diseased Kidney, 737 Developmental and Maturational Differences in Assessment of Renal Function, 738 63 GLOMERULOTUBULAR DYSFUNCTION AND ACUTE RENAL FAILURE, 741 Deborah P. Jones, Russell W. Chesney, Aaron L. Friedman Pathophysiology of Acute Renal Failure, 741 Classification of Acute Glomerulotubular Dysfunction, 746 Contents xxvii Specific Renal Diseases that May Lead to Acute Renal Failure, 750 64 PEDIATRIC RENAL REPLACEMENT THERAPY, 767 William E. Smoyer, Norma J. Maxvold, Robert T. Remenapp, Timothy E. Bunchman Indications for Therapy, 767 Peritoneal Dialysis, 767 Continuous Hemofiltration, 771 Continuous Hemofiltration on Extracorporeal Membrane Oxygenation, 775 Outcome, 776 Summary, 777 65 RENAL PHARMACOLOGY, 779 Thomas P. Green Use of Drugs to Augment Renal Function, 779 Effect of Renal Insufficiency on Therapeutics, 783 Nephrotoxicity of Drugs, 785 Section E Metabolism and Endocrinology 66 CELLULAR METABOLIC MACHINERY AND ENERGY METABOLISM, 788 Gregory A. Hollman, Waldemar E. Storm, Jerry J. Zimmerman General Cellular Metabolism, 788 Central Metabolic Pathways, 789 Oxidation of Nutrient Molecules, 794 Regulation of Cellular Metabolism, 795 Anaerobic Metabolism, 796 67 NUTRIENT METABOLISM IN RELATION TO THE SYSTEMIC STRESS RESPONSE, 799 John R. Wesley Altered Metabolic (Nutrient) Equilibrium in Critical Illness, 799 Starvation: Overall Fuel Conservation, 799 Effect of Stress (Trauma, Surgery, Burns, Sepsis), 801 Functional Consequences of Malnutrition, 807 Altered Substrate Utilization, 811 Energy Requirements, 813 Nutritional Support of the Critically 111 Child: Advantages and Limitations, 815 68 DISORDERS/DISEASES OF INBORN ERRORS OF METABOLISM THAT PRODUCE CRITICAL ILLNESS, 820 Jon A. Wolff, Enid Gilbert Barness. Lewis A. Barness Presentation and Evaluation, 820 Disorders of Amino Acid Metabolism, 822 Organic Acidemias, 823 Lipid Disorders, 824 Carbohydrate Disorders, 824 Other Enzyme Disorders, 825 Inborn Errors that Do Not Usually Produce Critical Illness, 825 xxviii Contents 69 DISORDERS OF THE ENDOCRINE SYSTEM RELEVANT TO PEDIATRIC CRITICAL ILLNESS, 826 David B. Allen Adrenal Cortical Insufficiency, 826 Adrenal Medullary Hyperfunction: Pheochromocytoma, 829 Thyroid Disorders and Responses to Critical Illness, 831 Thyrotoxic Crisis (Thyroid Storm), 832 Euthyroid Sick Syndrome and Hypothyroidism, 833 Glucose Homeostasis: Initial Evaluation and Treatment of Hypoglycemia, 834 Disorders of Calcium Homeostasis, 838 Hypocalcemia, 838 Hypercalcemia, 840 Anabolic Hormone Therapy: Human Growth Hormone and Insulin Like Growth Factor 1, 841 70 DIABETIC KETOACIDOSIS, 844 Ram K. Menon, Mark A. Sperling Definition, 844 Biochemical Pathophysiology, 844 Section F Hematology 71 STRUCTURE AND FUNCTION OF HEMATOPOIETIC ORGANS, 853 Seth J. Corey, Julie Blatt Structure and Function of the Bone Marrow, 853 Hematopoiesis, 854 Structure and Function of the Secondary Lymphoreticular System, 861 72 HEMATOLOGY ONCOLOGY PROBLEMS IN THE INTENSIVE CARE UNIT, 863 Diane J. Nugent, Michael D. Tarantino Anemia, 863 Hematological Malignancies, 869 Thrombocytopenia, 871 73 BASICS OF TRANSFUSION MEDICINE, 877 Kurt C. Gunter, Naomi L.C. Luban Anticoagulants and the Storage Lesion, 877 Components and Derivatives, 878 Specialized Blood Products, 884 Risks of Transfusion Transmitted Diseases, 886 Choice of Resuscitation Fluids, 886 Erythropoietin, 887 Alternative Products, 887 74 HEMATOPOIETIC STEM CELL TRANSPLANTATION, 890 Ralph R. Quinones Fundamentals of BMT, 890 Complications, 895 Conclusions, 901 Section G Gastroenterology 75 GASTROINTESTINAL STRUCTURE AND FUNCTION, 904 David M. Steinhorn Nutrition, Digestion, and Absorption, 904 Regulation of Electrolyte and Water Movement, 908 Pancreas, 909 Hepatobiliary System, 910 Host Defense Mechanisms of the Gut: Immunology and Microbiology, 913 Testing of the Gastrointestinal Tract in the ICU, 915 76 DISORDERS AND DISEASES OF THE GASTROINTESTINAL TRACT AND LIVER, 919 Samuel A. Kocoshis, Philip E. Putnam Gastrointestinal Evaluation of the Critically 111 Child, 919 Life Threatening Complications of Gastrointestinal Disorders, 923 77 LIVER TRANSPLANTATION, 933 Jerril Green, Joe Carcillo, Jorges Reyes Indications for Liver Transplantation in Children, 933 Preoperative Management, 934 Surgical Procedure, 935 Reduced Size Grafts, Split Liver Grafts, and Living Related Donor Transplantation, 937 Postoperative Management, 938 Neurological Complications, 941 Immunosuppression, 943 Long Term Critical Complications of Liver Transplantation, 944 Conclusion, 945 Section H Organ Systems and Failure 78 MOLECULAR ORIGINS OF CELLULAR INJURY, 946 Michael Vespasiano, Jerry J. Zimmerman General Origins of Cellular Injury, 946 Cellular Stress Responses, 946 Paramount Role of Oxyradical Species, 948 Secondary Injury Caused by Inflammation, 950 Alterations in ATP Synthesis, 950 Histopathological Manifestations, 950 Disrupted Calcium Homeostasis, 950 Lysis vs. Apoptosis, 952 79 MULTIPLE ORGAN DYSFUNCTION SYNDROME, 955 David M. Steinhorn, Frank B. Cerra Historical Perspective, 955 Clinical Epidemiology, 956 Pathogenesis, 958 Systemic Physiology, 959 Metabolic Manifestations, 960 Microbiology, 962 Current Therapy and Future Directions, 962 Section I Immunity and Infectious Disease 80 STRUCTURE AND FUNCTION OF THE IMMUNE SYSTEM, 966 Richard Hong Elements of the Immune System, 966 Functions of the Peripheral Lymphoid Tissue, 971 Functions of the Central Lymphoid Tissue, 975 Control of the Immune Response, 976 Summary, 977 81 INFECTION AND THE HOST RESPONSE, 979 M. Michele Mariscalco Definitions and Historical Perspective, 979 Recognition of Antigen, 979 Soluble Components of Inflammation, 980 Phagocytic Cells, 985 Other Cells Important to Host Defense, 988 Control of Inflammation, 988 82 CONGENITAL IMMUNODEFICIENCY, 995 Sheldon D. Horowitz T Cell Deficiency, 995 Other T Lymphocyte Related Immunodeficiency Diseases, 997 B Cell Deficiency, 997 Complement Deficiency, 999 Neutrophil Deficiency, 1000 Summary, 1001 83 PEDIATRIC AIDS IN THE ICU, 1004 Gwenn E. McLaughlin, G. Patricia Cantwell Diagnosis and Classification, 1004 Epidemiology, 1005 Pulmonary Complications and Respiratory Failure, 1005 Cardiovascular Complications, 1008 Septic Shock, 1009 Renal Failure, 1009 Abdominal Complications, 1010 Malignancies, 1012 Neurological Complications, 1012 Ethical Issues, 1013 84 IMMUNOLOGICAL MANAGEMENT OF CHILDREN UNDERGOING SOLID ORGAN TRANSPLANTATION, 1018 Allan D. Kirk, Stephen C. Rayhill, Jon S. Odorico, Munci Kalayoglu, Stuart J. Knechtle, John D. Pirsch, Hans W. Sollinger, Robert B. Love, Anthony M. D Alessandro Mechanisms of Allograft Rejection, 1018 Immunosuppressive Strategy, 1020 Specific Immunosuppressive Agents, 1020 New Immunosuppressive Agents, 1026 Complications of Immunosuppression, 1027 Clinical Transplant Immunosuppression, 1028 Conclusion, 1032 Contents xxix 85 NOSOCOMIAL INFECTIONS IN THE PICU, 1035 Jacques Lacroix, Peter Skippen, Peter Cox, Joanne M. Langley, Anne Matlow, Geoffrey Barker, E. Lee Ford Jones Morbidity, Mortality, and Cost of Nosocomial Infections, 1035 Epidemiology, 1035 Predisposing Factors in Critically 111 Patients, 1040 Site Specific Infections, 1042 Nosocomial Respiratory Tract Infections, 1045 Wound Infection and Surgical Prophylaxis, 1051 Urinary Tract Infection Associated with Catheterization, 1052 Other Infections, 1052 Infection Control Measures, 1053 86 ANTIMICROBIAL USE IN PEDIATRIC CRITICAL CARE, 1060 Michael Radetsky Antimicrobials, 1060 Synopsis of Infectious Disease Syndromes, 1062 87 SEPSIS/SEPTIC SHOCK, 1088 Jerry J. Zimmerman Epidemiology, 1088 Definitions, 1088 Biochemical Pathogenesis, 1089 Pathophysiology, 1092 Therapeutic Intervention, 1094 88 PEDIATRIC INFECTIOUS DISEASE, 1101 P. Joan Chesney Toxic Shock Syndrome, 1101 Severe Invasive Group A Streptococcal Disease, 1104 Rocky Mountain Spotted Fever, 1105 Hemorrhagic Shock and Encephalopathy Syndrome, 1107 Reye s Syndrome, 1107 Multidrug Resistant Bacteria and Invasive Infections, 1108 Hantavirus Pulmonary Syndrome, 1110 Ehrlichiosis, 1110 Cat Scratch Disease: Encephalopathy and Hepatosplenic Involvement, 1111 89 COLLAGEN VASCULAR DISEASE, 1115 Michael L. Miller Systemic Lupus Erythematosus, 1115 Juvenile Rheumatoid Arthritis, 1120 Dermatomyositis, 1122 Other Rheumatic Conditions, 1124 90 ANAPHYLAXIS, 1129 Michael Ritter, Robert F. Lemanske, Jr. Epidemiology, 1129 Clinical Features, 1130 Pathogenesis, 1131 Differential Diagnosis, 1136 Treatment, 1136 Summary, 1138 xxx Contents PART III Environmental Hazards 91 PRINCIPLES OF TOXIN ASSESSMENT AND SCREENING, 1142 Alan D. Woolf, Frederick H. Lovejoy, Jr. Epidemiology, 1142 Common Agents Involved, 1142 Resources for the Clinician, 1142 General Assessment of the Poisoned Patient, 1143 92 PRINCIPLES AND TECHNIQUES OF DETOXIFICATION, 1150 Alan D. Woolf, Frederick H. Lovejoy, Jr. Stabilization, 1150 Efforts to Reduce Absorption of Toxins, 1151 Enhancing Elimination, 1152 Antidotal Therapies, 1155 93 INTERVENTION FOR SPECIFIC TOXINS, 1157 Donald D. Vernon, William Banner, Jr. Analgesics, 1157 Salicylates, 1158 Anticholinergics, 1158 Cyclic Antidepressants, 1159 Alcohols, 1160 Narcotics, 1161 Cocaine, 1162 Anticonvulsants, 1162 Insecticides, 1163 Hydrocarbons, 1164 Cardiac Agents, 1164 Toxins Producing Methemoglobin, 1165 Iron, 1166 Theophylline/Caffeine, 1166 94 SNAKE ENVENOMATIONS, 1171 John B. Sullivan, Jr., Leslie Boyer Crotalidae (Pet Vipers), 1171 Envenomation Syndromes, 1173 Management of Crotalidae Envenomation, 1173 Snakebite in Pregnancy, 1178 Avoiding Pitfalls and Errors, 1178 Elapidae, 1178 Clinical Syndrome of Coral Snake Venom Poisoning, 1179 95 ENVIRONMENTAL HEAT AND COLD INJURIES, 1181 Julie A. Kiley, Mel D. Robinson Cold Injury, 1181 Heat Injury, 1184 96 NEAR DROWNING, 1190 Ashok P. Sarnaik, Mary W. Lieh Lai Definitions, 1190 Epidemiology, 1190 Pathophysiological Considerations, 1190 Management, 1193 Prognosis, 1196 97 BURN AND INHALATION INJURIES, 1198 Hugo F. Carvajal, James A. Griffith Pathogenesis and Pathophysiology, 1198 Treatment, 1201 PART IV Trauma 98 EVALUATION, STABILIZATION, AND INITIAL MANAGEMENT AFTER MULTIPLE TRAUMA, 1212 Grace M. Young, Martin R. Eichelberger The Pediatric Trauma Center, 1212 The Pediatric Trauma Response Team, 1214 Primary Survey, 1214 Secondary Survey, 1218 Definitive Care Phase, 1219 99 EVALUATION AND MANAGEMENT OF PEDIATRIC HEAD TRAUMA, 1221 Mark S. Dias, John Borchers, Lynn J. Hernan, Micam W. Tullous Pathophysiology of Brain Injury, 1221 Assessment and Initial Management, 1223 Clinical Features of Head Trauma, 1227 Special Problems in Childhood Head Injuries, 1234 Acute Management of Elevated Intracranial Pressure, 1237 100 THORACIC INJURIES IN CHILDREN, 1249 Michael G. Caty, Victor F. Garcia, Martin R. Eichelberger, Richard G. Azizkhan Epidemiology, 1249 Diagnosis and Immediate Management of the Child with Chest Injuries, 1249 Fractures of the Bony Thorax, 1250 Pulmonary Contusion, 1251 Pneumothorax/Hemothorax ,1251 Cardiac Injuries, 1253 Aortic and Great Vessel Injuries, 1253 Other Injuries, 1254 Summary, 1254 101 ABDOMINAL TRAUMA IN PEDIATRIC CRITICAL CARE, 1256 James C. Gilbert, Patrick V. Bailey Mechanisms and Patterns of Injury, 1256 Evaluation and Resuscitation, 1256 Penetrating Abdominal Trauma, 1258 Definitive Radiographic Assessment in Pediatric Abdominal Trauma, 1258 ICU Nonoperative Management Strategies, 1259 Specific Organ Injuries and Management, 1259 PART V Pharmacology 102 PRINCIPLES OF DRUG DISPOSITION IN THE CRITICALLY ILL CHILD, 1268 Jeffrey L. Blumer Children, the Therapeutic Orphans, 1268 Drug Disposition in Infants and Children, 1269 Pharmacokinetic Principles, 1278 Critical Care Therapeutics, 1281 103 RECEPTOR PHYSIOLOGY, SIGNAL TRANSDUCTION, AND SECOND MESSENGERS, 1286 Kathryn L. Weise General Principles, 1286 Signal Transduction Mechanisms, 1288 Clinical Manifestations of Receptor Physiology, 1292 104 DRUG DRUG INTERACTIONS, 1301 Brian L. LaRowe Absorption, 1301 Complex Formation, 1302 Distribution, 1305 Receptor Sites, 1307 Metabolism, 1308 Excretion, 1311 105 PHARMACOLOGICAL IATROGENIA (ADVERSE DRUG REACTIONS), 1314 Timothy D. Wolf Definitions, 1314 Hepatotoxicity, 1314 Adverse Pulmonary Reactions, 1315 Nephrotoxicity, 1316 Pancreatic Toxicity, 1317 Blood Dyscrasias, 1318 PART VI Anesthesia/Analgesia Aspects of Pediatric Critical Care 106 ORGAN SYSTEM CONSIDERATIONS THAT AFFECT ANESTHETIC MANAGEMENT, 1324 Peter J. Davis, Joel B. Sarner Cardiovascular Performance, 1324 Anemia and Transfusion, 1325 Respiratory Failure, 1326 Neurologic Injury, 1327 Hepatic Dysfunction, 1329 Intravenous Alimentation, 1331 Summary, 1331 107 NEUROMUSCULAR BLOCKING AGENTS, 1334 D. Ryan Cook Neuromuscular Junction and Neuromuscular Transmission, 1334 Contents xxxi Structural and Functional Development of Neuromuscular System, 1337 Dose Response Relationships, 1338 Characteristics of Specific Agents, 1341 Modes of Evaluation of Neuromuscular Transmission, 1349 Myoneuropathies, 1349 Reversal of Neuromuscular Blockade, 1349 108 ANESTHETIC PRINCIPLES AND OPERATING ROOM ANESTHESIA REGIMENS, 1353 John H. Arnold, James C. Fackler Anesthetic Agents, 1353 Anesthetic Techniques, 1358 Specific Anesthetic Considerations, 1359 109 ANALGESIA AND SEDATION IN PEDIATRIC CRITICAL CARE, 1363 Gregory A. Hollman Approach to Comfort Control in the PICU, 1363 Drugs for Sedation, 1364 Other Sedatives, 1367 Drugs for Sedation and Analgesia, 1369 Tolerance and Dependence, 1375 Conclusions, 1375 110 MALIGNANT HYPERTHERMIA, 1380 Barbara W. Brandom Pathophysiology, 1380 Porcine Model, 1380 Clinical Recognition of an Episode in Humans, 1382 Factors that Trigger MH in Humans, 1384 The Course of a Clinical Episode of MH in Humans, 1384 Treatment of an Episode of MH, 1384 Symptomatic Treatment, 1385 Recrudescence, 1386 Potential Systemic Complications, 1386 Identification of Patients at Risk, 1386 The Safe Anesthetic, 1387 Dantrolene, 1387 In Vitro Caffeine Halothane Contracture Testing, 1387 Noninvasive Tests of MH Susceptibility, 1388 Neuroleptic Malignant Syndrome, 1388 111 POSTANESTHESIA RECOVERY IN THE PEDIATRIC INTENSIVE CARE UNIT, 1391 /. David Todres Recovery from Anesthesia, 1391 Transport to the Pediatric Intensive Care Unit, 1393 Arrival in the Intensive Care Unit, 1393 Recovery Problems, 1393 PART VII Cardiopulmonary Resuscitation 112 PHYSIOLOGICAL FOUNDATIONS OF CARDIOPULMONARY RESUSCITATION, 1400 Charles L. Schleien, John W. Kuluz xxxii Contents Mechanisms of Blood Flow, 1400 Newer CPR Techniques, 1404 Pharmacology, 1407 113 THE PERFORMANCE OF CPR IN INFANTS AND CHILDREN, 1420 Judith E. Brill Epidemiology of Cardiac Arrest, 1420 Performance of CPR, 1421 Resuscitation Procedures, 1422 Airway Management, 1424 Rescue Breathing and Artificial Ventilation, 1425 Supporting the Circulation, 1426 Vascular Access for Resuscitation, 1428 Endotracheal Drug Administration, 1428 Fluid Administration During CPR, 1429 Drug Therapy for Resuscitation, 1429 Defibrillation, 1432 Special Issues and Procedures in Resuscitation, 1433 Complications of CPR, 1434 Summary, 1436
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spelling	Pediatric critical care Bradley P. Fuhrman ; Jerry J. Zimmerman 2. ed. St. Louis [u.a.] Mosby 1998 XXXII, 1438 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Intensive care gtt Kinderen gtt Kind Child Critical Care Infant Pediatric intensive care Fuhrman, Bradley P. Sonstige oth Zimmerman, Jerry J. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008082093&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Pediatric critical care Intensive care gtt Kinderen gtt Kind Child Critical Care Infant Pediatric intensive care
title	Pediatric critical care
title_auth	Pediatric critical care
title_exact_search	Pediatric critical care
title_full	Pediatric critical care Bradley P. Fuhrman ; Jerry J. Zimmerman
title_fullStr	Pediatric critical care Bradley P. Fuhrman ; Jerry J. Zimmerman
title_full_unstemmed	Pediatric critical care Bradley P. Fuhrman ; Jerry J. Zimmerman
title_short	Pediatric critical care
title_sort	pediatric critical care
topic	Intensive care gtt Kinderen gtt Kind Child Critical Care Infant Pediatric intensive care
topic_facet	Intensive care Kinderen Kind Child Critical Care Infant Pediatric intensive care
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008082093&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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