Myasthenia gravis and related diseases: disorders of the neuromuscular junction
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
1998
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| Schriftenreihe: | New York Academy of Sciences: Annals of the New York Academy of Sciences
841 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XVII, 838 S. Ill., graph. Darst. |
| ISBN: | 1573311197 1573311200 |
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| 245 | 1 | 0 | |a Myasthenia gravis and related diseases |b disorders of the neuromuscular junction |c ed. by David P. Richman |
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| 490 | 1 | |a New York Academy of Sciences: Annals of the New York Academy of Sciences |v 841 | |
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Miastenija gravis |v Kongresi | |
| 650 | 4 | |a Myasthenia gravis |v Congresses | |
| 650 | 4 | |a Neuromuscular junction |x Physiopathology |v Congresses | |
| 650 | 4 | |a Živčnomišični stik |x Fiziopatologija |v Kongresi | |
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Datensatz im Suchindex
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 841
May 13, 1998
MYASTHENIA GRAVIS
AND RELATED DISEASES
DISORDERS OF THE
NEUROMUSCULAR JUNCTION
Editor and Conference Organizer
David P. Richman
CONTENTS
Introduction. By David P. Richman xvii
Part I. Biology of the Neuromuscular Junction
Agrin Receptors at the Skeletal Neuromuscular Junction. By Joshua R. Sanes,
Elizabeth D. Apel, Medha Gautam, David Glass, R. Mark Grady,
Paul T. Martin, Mia C. Nichol, and George D. Yancopoulos 1
Evidence for an Association between Human Acetylcholine Receptor and
Rapsyn. By Alexandra Buckel, Esther James, Leslie Jacobson, Jeike
Biewenga, David Beeson, and Angela Vincent 14
Interaction between the Nicotinic Acetylcholine Receptor and Grb2:
Implications for Signaling at the Neuromuscular Junction. By Marcie
COLLEDGE AND STANLEY C. FROEHNER 17
Fourteen Newly Recognized Proteins at the Human Neuromuscular Junctions
—and Their Nonjunctional Accumulation in Inclusion Body Myositis. By
Valerie Askanas, W. King Engel, and Renate B. Alvarez 28
Electrophysiology of Postsynaptic Activation. By Robert L. Ruff 57
Molecular and Antigenic Structure of Nicotinic Acetylcholine Receptors.
By Jon Lindstrom, Xiao Peng, Alexander Kuryatov, Edward Lee, Rene
Anand, Volodymyr Gerzanich, Fan Wang, Gregg Wells, and Mark
Nelson 71
This volume is the result of the Ninth International Conference on Myasthenia Gravis and
Related Disorders, which was sponsored jointly by the New York Academy of Sciences and the
Myasthenia Gravis Foundation of America, Inc. (Host California Chapter), and held on May
7 10, 1997, in Santa Monica, California.
A Role for a( 187 199) in the Conversion of Agonist Binding Energy to the
Opening of the Acetylcholine Receptor Ion Channel. By Robert H.
Fairclough, Eswari Gudipati, Mike Y. Lin, George M. Twaddle,
David P. Richman, David A. Burkwall, and Robert Josephs 87
The Mongoose Neuronal Acetylcholine Receptor (a7) Binds a Bungarotoxin.
By Shany Ariel, Orna Asher, Dora Barchan, Michael Ovadia, and
Sara Fuchs 93
How Does the Mongoose Cope with a Bungarotoxin?: Analysis of the
Mongoose Muscle AChR a Subunit. By Orna Asher, Monica Lupu Meiri,
Bo S. Jensen, Tamar Paperna, Yoram Oron, and Sara Fuchs 97
MAb 383C Binds to the a Subunit of the Acetylcholine Receptor Associated
with the High Affinity Tubocurarine Site. By Mike Y. Lin, George M.
Twaddle, Eswarj Gudipati, David P. Richman, and Robert H.
Fairclough 101
Distance between a Cys 192 of the Acetylcholine Receptor and Rhodamine
labeled a Bungarotoxin Complexed to the Receptor. By Eswari Gudipati,
Laura Silvian, Viswanatham Katta, and Robert H. Fairclough .... 104
Measurement of the Dissociation Rate Constants of a Bungarotoxin from the
Acetylcholine Receptor Low and High Affinity Tubocurarine Sites. By
Mike Y. Lin, George M. Twaddle, Eswari Gudipati, and Robert H.
Fairclough 108
Control of Gene Expression of Human Muscle Acetylcholine Receptor. By
P. P. Nichols and D. M. W. Beeson Ill
Isolation of Ca2+ Channel a1A, a2, and 0 Subunit Segments from Human
Spinal Cord RNA. By Ravindra K. Hajela and William D. Atchison . 115
Transient Translocation of N type Calcium Channels from Secretory
Granules to the Cell Surface. By Maria Passafaro, Elena Taverna,
Elena Morlacchi, Patrjzia Rosa, Francesco Clementi, and
Emanuele Sher 119
Part II. Nonimmune Disorders of the Neuromuscular Junction
Pathogenesis of Human Botulism. By Rjcardo A. Maselli 122
Congenital Myasthenic Syndromes: New Insights from Molecular Genetic and
Patch Clamp Studies. By Andrew G. Engel, Kinji Ohno, Margherita
Milone, and Steven M. Sine 140
Congenital Myasthenic Syndrome (CMS) Type la: Clinical and Genetic
Diversity. By Lefkos T. Middleton, Kyproula Christodoulou,
Feza Deymeer, Piraye Serdaroglu, Coskun Ozdemir, Abdel Karim
Al Qudah, Ahmad Al Shehab, Ioannis Mavromatis, Ioannis
Mylonas, Amelia Evoli, Marios Tsingis, Eleni Zamba, and
Kyriakos Kyriallis 157
Genetic Manipulation of AChR Responses Suggests Multiple Causes of
Weakness in Slow Channel Syndrome. By Christopher M. Gomez,
Ricardo Maselli, Joan M. Williams, Bula B. Bhattacharyya,
Robert L. Wollmann, and John W. Day 167
Congenital Myasthenic Syndromes: Studies of the AChR and Other Candidate
Genes. By D. Beeson, C. Newland, R. Croxen, A. Buckel, F Y. Li, C.
Larsson, M. Tariq, A. Vincent, and J. Newsom Davis 181
Congenital Myasthenic Syndrome Caused by Novel Loss of Function Mutations
in the Human AChR e Subunit Gene. By Margherita Milone, Kinji Ohno,
Takayasu Fukudome, Xin Ming Shen, Joan Brengman, Robert C. Griggs,
and Andrew G. Engel 184
Frameshifting and Splice Site Mutations in the Acetylcholine Receptor e
Subunit Gene in Three Turkish Kinships with Congenital Myasthenic
Syndromes. By Kinji Ohno, Banu Anlar, Emire Ozdirim, Joan M.
Brengman, and Andrew G. Engel 189
A Single Nucleotide Deletion in the e Subunit of the Acetylcholine Receptor
(AChR) in Five Congenital Myasthenic Syndrome Patients with AChR
Deficiency. By Rebecca Croxen, David Beeson, Claire Newland,
Maria Betty, Angela Vincent, and John Newsom Davis 195
AChR Channel Blockade by Quinidine Sulfate Reduces Channel Open
Duration in the Slow Channel Congenital Myasthenic Syndrome. By
Takayasu Fukudome, Kinji Ohno, Joan M. Brengman, and Andrew
G. Engel 199
Safety and Efficacy of Quinidine Sulfate in Slow Channel Congenital
Myasthenic Syndrome. By C. Michel Harper and Andrew G. Engel . 203
Rhodamine labeled Alpha Bungarotoxin Allows Visualization of End
Plates in Congenital End Plate Acetylcholinesterase Deficiency (CEAD).
By Mark A. Agius, Ricardo A. Maselli, Shan Zhu, Robert H.
Fairclough, Mike Y. Lin, and William Ellis 207
Part III. Immune Regulation and Autoimmunity
Immune Regulation and Myasthenia Gravis. By Samia Ragheb and Robert
P. Lisak 210
Mechanisms and Genetics of Autoimmunity. By Argyrios N. Theofilopoulos
and Dwight H. Kono 225
T Cell Tolerance and the Thymus. By Jonathan Sprent and Hidehiro
Kishimoto 236
Principles of Paraneoplastic Syndromes. By Edward J. Dropcho 246
Part IV. Autoimmune (Acquired) Myasthenia Gravis
Factors That Determine the Severity of Experimental Myasthenia Gravis. By
Daniel B. Drachman, Kevin R. McIntosh, and Bingzhi Yang 262
T Cell Recognition of the Acetylcholine Receptor in Myasthenia Gravis. By
BlANCA M. CoNTI FlNE, DURAISWAMY NaVANEETHAM, PeTER I.
Karachunski, Raghavanpillai Raju, Brenda Diethelm Okita,
David Okjta, James Howard, Jr., and Zenq Yu Wang 283
Acetylcholine Receptor Epitopes in Ocular Myasthenia. By Henry J.
Kaminski 309
Biosynthetic and Synthetic AChR Sequences to Study T Cells in Myasthenia
Gravis. By B. Diethelm Okita, G. Wells, A. Kuryatov, D. Okita,
J. Howard, J. Lindstrom, and B. M. Conti Fine 320
Acetylcholine Receptor specific CD4+ T Cells in Myasthenia Gravis Patients
Have Individual, but Restricted TCR Vp Usage. By Raghavanpillai Raju,
Duraiswamy Navaneetham, Maria Pia Protti, Robert M. Horton,
Bobbi L. Hoppe, James Howard, Jr., and Bianca M. Conti Fine 324
Thl Cells of Myasthenia Gravis Patients Recognize Multiple Epitopes on the
Muscle Acetylcholine Receptor a Subunit. By Zeng Yu Wang, David K.
Okita, James F. Howard, Jr., and Bianca M. Conti Fine 329
CD4+ Epitope Spreading and Differential T Cell Recognition of Muscle
Acetylcholine Receptor Subunits in Myasthenia Gravis. By Zeng Yu Wang,
David K. Okita, James F. Howard, Jr., and Bianca M. Conti Fine . . . 334
Coimmunization of MHC Class II Competitor Peptides during Experimental
Autoimmune Myasthenia Gravis Induction Resulted Not Only in a
Suppressed, but Also in an Altered Immune Response. By Marca H. M.
Wauben, Astrid C. W. E. Hoedemaekers, Yvo M. F. Graus, Josee P. A.
Wagenaar, Willem Van Eden, and Marc H. De Baets 338
Low Level of TGF p in Early Stages of Myasthenia Gravis. By A. P.
Batocchi, A. Evoli, M. Lino, L. Majolini, C. Minisci, and P. Tonali . . 342
Secretion of TH 2 type Cytokines by Acetylcholine Receptor (AChR)
stimulated Mononuclear Cells. By Samia Ragheb and Robert P. Lisak . 347
In Vitro Production of Antiacetylcholine Receptor Antibody and IgG by
Peripheral Blood Lymphocytes of Patients with Myasthenia Gravis. By
Hiroaki Yoshikawa, Katsuaki Satoh, Kazuo Iwasa, and Masaharu
Takamori 351
Identification of a Novel HLA Class II Association with DQB 1*0502 in an
Italian Myasthenic Population. By Fulvio Baggi, Carlo Antozzi,
Francesca Andreetta, Paolo Confalonieri, Emilio Ciusani, Ann B.
Begovich, Henry A. Erlich, Ferdinando Cornelio, and Renato
Mantegazza 355
Susceptibility of HLA DR3 Transgenic Mice to Experimental Autoimmune
Myasthenia Gravis. By R. Raju, W Z. Zhan, P. Karachunski, G. C. Sii ck,
B. M. Conti Fine, and C. S. David 360
Epitope Spreading in Experimental Autoimmune Myasthenia Gravis. By
Mark A. Agius, George M. Twaddle, and Robert H. Fairclough . . . 365
Myasthenia Gravis with Thymic Hyperplasia Is Associated with
Polymorphisms in the Tumor Necrosis Factor Region. By P. Hjelmstrom,
C. S. Peacock, R. Giscombe, R. Pirskanen, A. K. Lefvert, J. M.
Blackwell, and C. B. Sanjeevi 368
Thymus, Thymoma, and Specific T Cells in Myasthenia Gravis. By D. Beeson,
A. P. Bond, L. Corlett, S. J. Curnow, M. E. Hill, L. W. Jacobson, C.
MacLennan, A. Meager, A M. Moody, P. Moss, N. Nagvekar, J.
Newsom Davis, N. Pantic, I. Roxanis, E. G. Spack, A. Vincent, and N.
Willcox 371
Thymocytes and Cultured Thymic Epithelial Cells Express Transcripts
Encoding a 3, a 5, and p 4 Subunits of Neuronal Nicotinic Acetylcholine
Receptors: Preferential Transcription of the a 3 and (3 4 Genes by Immature
CD4+8+ Thymocytes and Evidence for Response to Nicotine in Thymocytes.
By Mirta Mihovilovic, Stephen Denning, Yun Mai, Clare M. Fisher,
Leona P. Whichard, Dhavalkumar D. Patel, and Allen D. Roses ... 388
Regulation of Acetylcholine Receptor Alpha Subunit mRNA Expression in
Myasthenic Thymus. By Y. Zheng, L. M. Wheatley, T. Liu, and A. I.
Levinson 393
Respective Role of Thymus and Muscle in Autoimmune Myasthenia Gravis.
By N. Moulian, A. Wakkach, T. Guyon, S. Poea, A. Aissaoui, P.
Levasseur, S. Cohen Kaminsky, and S. Berrih Aknin 397
Muscle Nicotinic Acetylcholine Receptor mRNA Expression in Hyperplastic
and Neoplastic Myasthenia Gravis Thymus. By C. A. MacLennan, D.
Beeson, N. Willcox, A. Vincent, and J. Newsom Davis 407
Expression of Muscle Proteins in Thymomas of Patients with Myasthenia
Gravis. By Yohan Liyanage, Michelle Teo, Cal MacLennan, Alex
Buckel, David Beeson, Nick Willcox, John Newsom Davis, and
Angela Vincent 411
Antiacetylcholine Receptor Fab Fragments Isolated from Thymus derived
Phage Display Libraries from Myasthenia Gravis Patients Reflect
Predominant Specificities in Serum and Block the Action of Pathogenic
Serum Antibodies. By Yvo F. Graus, Marc H. De Baets, and Dennis
R. Burton 414
Production of Fab Fragments against the Human Acetylcholine Receptor from
Myasthenia Gravis Thymus Lambda and Kappa Phage Libraries. By I.
Matthews, J. Farrar, S. McLachlan, B. Rapoport, J. Newsom Davis,
N. Willcox, and A. Vincent 418
Titin Transcripts in Thymomas. By Geir Olve Skeie, Alexandra Freiburg,
bernhard kolmerer, siegfried labeit, johan a. aarli, and nlls erik
Gilhus 422
Using Histochemical Methods to Study Pathological Features of Hyperplastic
Thymus and Thymoma in Patients with Myasthenia Gravis. By L. H. Tu,
G. Y. Cai, X. M. Zhu, and R. Q. Zhang 427
Percutaneous Paracentesis into Thymus Gland for Intervention Treatment of
Myasthenia Gravis: Report of Ten Cases. By L. H. Tu, J. M. Jiang, R. Q.
Zhang, Q. L. Xie, W. Xu, Y. Chen, T. H. Zhang, J. J. Ding, Z. Y. Zhang,
S. Y. Wang, X. Y. Sun, P. J. Wang, and T. Z. Lu 430
Drug induced Autoimmune Myasthenia Gravis. By Audrey S. Penn, Barbara
W. Low, Israeli A. Jaffe, Liang Luo, and Jeffrey J. Jacques 433
Antibody Effector Mechanisms in Myasthenia Gravis: The Complement
Hypothesis. By David P. Richman, Mark A. Agius, Christine A. Kirvan,
Christopher M. Gomez, Robert H. Fairclough, Bonita L. DuPont, and
Ricardo A. Maselli 450
Expression and Initial Characterization of Recombinant Antiacetylcholine
Receptor Antibodies in Experimental Autoimmune Myasthenia Gravis.
By Christine A. Kjrvan, Shan Zhu, David P. Richman, and Mark
A. Agius 466
Homology of an Antiacetylcholine Receptor Monoclonal Antibody with a
Monoclonal Antibody to Campath 1 Antigen Suggests Usage of the
Same VH Genes. By Mark A. Agius, Christine A. Kirvan, and
Bharati Sanyal 469
Acetylcholine Receptor Antibody Measurements in Acquired Myasthenia
Gravis: Diagnostic Sensitivity and Predictive Value for Thymoma. By
Aatif M. Husain, Janice M. Massey, James F. Howard, and Donald
B. Sanders 471
Construction of Single Chain Fv Fragments of Anti MIR Monoclonal
Antibodies. By S. J. Tzartos, P. Tsantili, D. Papanastasiou, and A.
Mamalaki 475
Epitope Analysis of AChR Ab in Patients with Myasthenia Gravis Using
Sensitive Enzyme Immunoassay. By Masatoshi Hayashi, Takeyuki
KOHNO, JUNJI YOSHINAGA, AND KaICHI KlDA 478
Antibodies Affecting Ion Channel Function in Acquired Neuromyotonia, in
Seropositive and Seronegative Myasthenia Gravis, and in Antibody
mediated Arthrogryposis Multiplex Congenita. By Angela Vincent,
Leslie Jacobson, Paul Plested, Agata Polizzi, Teresa Tang, Sietske
Riemersma, Claire Newland, Sara Ghorazian, Jeremy Farrar, Cal
MacLennan, Nicholas Willcox, David Beeson, and John
Newsom Davis 482
Morvan s Fibrillary Chorea: Electrodiagnostic and In Vitro Microelectrode
Findings. By R. A. Maselli, M. Agius, E K. Lee, N. Bakshi, R. N.
Mandler, and W. Ellis 497
Seronegative Myasthenia Plasmas and Non IgG Fractions Transiently Inhibit
nAChR Function. By C. Paul Plested, John Newsom Davis, and Angela
Vincent 501
Muscle Striation Antibodies in Myasthenia Gravis: Diagnostic and Functional
Significance. By Johan A. Aarli, Geir Olve Skeie, Ase Mygland, and
Nils Erik Gilhus 505
Rapsyn Antibodies in Myasthenia Gravis. By Mark A. Agius, Shan Zhu,
Christine A. Kirvan, Anne L. Schafer, Mike Y. Lin, Robert H.
Fairclough, Joel J F. Oger, Tariq Aziz, and Johan A. Aarli 516
Antibodies to AChR, Synapse organizing Proteins, Titin, and Other Muscle
Proteins in Morvan s Fibrillary Chorea. By Mark A. Agius, Shan Zhu,
Eun Kyu Lee, Johan A. Aarli, Christine Kirvan, Robert H. Fairclough,
and Ricardo Maselli 522
Antirapsyn Antibodies Occur Commonly in Patients with Lupus. By Mark
A. Agius, Shan Zhu, and Johan A. Aarli 525
Antirapsyn Antibodies in Chronic Procainamide associated Myopathy
(CPAM). By Mark A. Agius, Shan Zhu, and Robert H. Fairclough .. 527
Myasthenia Gravis associated Ryanodine Receptor Antibodies Inhibit Binding
of Ryanodine to Sarcoplasmic Reticulum. By G. O. Skeie, P. K. Lunde,
O. M. Sejersted, A. Mygland, J. A. Aarli, and N. E. Gilhus 530
Sera from Myasthenia Gravis Patients Recognize the PEVK Domain of Titin.
By Mirta Mihovilovic, Yun Mai, Carol Austin, and Allen D. Roses . 534
Anti titin and Antiryanodine Receptor Antibodies in Myasthenia Gravis Patients
with Thymoma. By Fulvio Baggi, Francesca Andreetta, Carlo Antozzi,
Ornella Simoncini, Paolo Confalonieri, Siegfried Labeit, Ferdinando
Cornelio, and Renato Mantegazza 538
Motor Dysfunction and Autoantibodies in Spontaneous Thymoma Buffalo/
Mna Rats. By Kazuo Iwasa, Kiyonobu Komai, Tomoya Asaka, Eishun
Nitta, and Masaharu Takamori 542
Agrin induced Aggregation of Acetylcholine Receptors in Muscles of Rats with
Experimental Autoimmune Myasthenia Gravis. By Mendell Rimer ... 546
Differential Susceptibility of Young and Old Rat Neuromuscular Junctions to
Antibody mediated AChR Degradation in Experimental Autoimmune
Myasthenia Gravis. By A. Hoedemaekers, J L. Bessereau, Y. Graus, T.
Guyon, J P. Changeux, S. Berrih Aknin, P. Van Breda Vriesman, and
M. De Baets 550
Immunization of bml2 Mice with High Doses of Acetylcholine Receptor
Overcomes Their Resistance to Experimental Autoimmune Myasthenia
Gravis. By Peter I. Karachunski, Norma S. Ostlie, Sijin Lei, David K.
Okita, Jon M. Lindstrom, and Bianca M. Conti Fine 555
Nasal Administration of Synthetic Acetylcholine Receptor T Epitopes Affects
the Immune Response to the Acetylcholine Receptor and Prevents
Experimental Myasthenia Gravis. By Peter I. Karachunski, Norma S.
Ostlie, David K. Okita, and Bianca M. Conti Fine 560
An Animal Model of Maternal Antibody mediated Arthrogryposis Multiplex
Congenita (AMC). By Leslie Jacobson, Agata Polizzi, and Angela
Vincent 565
Oral Administration of an Immunodominant TAChR Epitope Modulates
Antigen specific T Cell Responses in Mice. By C. Antozzi, F. Baggi,
F. Andreetta, O. Simoncini, R. Longhi, F. Cornelio, and R.
Mantegazza 568
Modulation of Experimental Autoimmune Myasthenia Gravis by
Recombinant Fragments of the Human Acetylcholine Receptor. By
Miriam C. Souroujon, Dora Barchan, and Sara Fuchs 572
IFN 7 Is Required to Induce Experimental Autoimmune Myasthenia Gravis.
By G X. Zhang, B G. Xiao, X F. Bai, A. Orn, P. H. Van Der Meide, and
H. Link 576
Cytokine Profiles of Experimental Autoimmune Myasthenia Gravis after
Treatment by the Synthetic Immunomodulator Linomide. By G X. Zhang,
L Y. Yu, F D. Shi, B G. Xiao, J. BjOrk, G. Hedlund, and H. Link 580
Effect of Anti idiotopic Antibody on the Course of Experimental Autoimmune
Myasthenia Gravis. By Mark A. Agius and Eric Yuen 584
Analysis of Risk Factors for Acquired Myasthenia in Dogs. By G. Diane
Shelton, Alan Schule, and Philip H. Kass 587
Apolipoprotein E in Myasthenia Gravis. By M. Sostarko, J. Sertic, N.
Greguric, A. Stavljenic Rukavina, Z. Brzovic, and V. Matic 592
Part V. Lambert Eaton Myasthenic Syndrome
The Role of Autoantibodies in Lambert Eaton Myasthenic Syndrome. By
Bethan Lang, Sally Waterman, Ashwin Pinto, Dominic Jones, Fraser
Moss, John Boot, Paul Brust, Mark Williams, Kenneth Stauderman,
Michael Harpold, Masakatsu Motomura, J. Wibe Moll, Angela
Vincent, and John Newsom Davis 596
Nicotinic Receptors and Calcium Channels in Small Cell Lung Carcinoma:
Functional Role, Modulation, and Autoimmunity. By E. Sher, A.
Codignola, M. Passafaro, P. Tarroni, V Magnelli, E. Carbone, and
F. Clementi 606
Antigenic Sites of the Voltage gated Calcium Channel in Lambert Eaton
Myasthenic Syndrome. By Masaharu Takamori, Kazuo Iwasa, and
Kjyonobu Komai 625
Role of L type and N type Voltage dependent Calcium Channels (VDCCs) on
Spontaneous Acetylcholine Release at the Mammalian Neuromuscular
Junction. By Adriana Losavio and SalomOn Muchnik 636
Activation of Opioid Receptors Inhibits Neuronal like Calcium Channels,
Distal Steps of Secretion, and Cell Proliferation in Human Small Cell Lung
Carcinoma Cells. By Agnese Codignola, Cristina Missale, PierFranco
Spano, Francesco Clementi, Emilio Carbone, and Emanuele Sher . . 646
Downregulation of Nicotinic Acetylcholine Receptors by Nerve Growth Factor
in Human Small Cell Lung Carcinoma Cell Lines. By Agnese Codignola,
Cristina Missale, PierFranco Spano, Francesco Clementi, and
Emanuele Sher 651
A Small Cell Lung Carcinoma Line and Subclone Expressing Nicotinic
Acetylcholine Receptors of Muscle and Neuronal Types. By Michele A.
Sciamanna, Guy E. Griesmann, and Vanda A. Lennon 655
Neuromuscular Blockade by Immunoglobulin G from Patients with Miller
Fisher Syndrome. By Brigitte Buchwald, Josef Dudel, and Klaus
V Toyka 659
An Autoimmune Animal Model of the Lambert Eaton Syndrome. By Yong I.
Kim, Eric H. Middlekauff, Michael P. Viglione, Jun Ichi Okutsu,
Yasushi Satoh, Naohide Hirashima, and Yutaka Kirino 670
Specificity of the Lambert Eaton Syndrome Antibodies: Downregulation of
P/Q type Calcium Channels in Bovine Adrenal Chromaffin Cells. By
Yong I. Kjm, Taick S. Nam, Sung H. Kim, Michael P. Viglione, and
Jun Kim 677
Neuronal Staining Patterns in Sera from Patients with Lambert Eaton
Myasthenic Syndrome. By Agata Pouzzi, Bethan Lang, Elizabeth
Amyes, John Newsom Davis, and Angela Vincent 684
Differential Effect of Lambert Eaton Myasthenic Syndrome Immunoglobulin
on Cloned Neuronal Voltage gated Calcium Channels. By Ashwin Pinto,
Fraser Moss, Bethan Lang, John Boot, Paul Brust, Mark Williams,
Kenneth Stauderman, Michael Harpold, and John Newsom Davis .. 687
Lambert Eaton Myasthenic Syndrome: Antigenicity of Recombinant Human
P/Q type Calcium Channel a, Subunit Putative Ion Pore Region (Domain
IV, S5 S6). By John L. Black, Guy E. Griesmann, Jean Erickson,
Thomas J. Kryzer, Geoffrey T. Lamke, and Vanda A. Lennon 691
Part VI. Current Diagnosis and Treatment of Myasthenia Gravis
Electrodiagnosis of Disorders of Neuromuscular Transmission. iiy Ricardo A.
Maselli 696
Mechanisms of Fatigue in Normal Young and Old Mice. By Murali Pagala,
Tatsuji Namba, and David Grob 712
Repetitive Nerve Stimulation in Studies of Respiratory Involvement in
Myasthenia Gravis. By U. Zifko, C. B. Bolton, and M. W. Nicolle .... 716
Plasma Exchange and Intravenous Immunoglobulin in Autoimmune
Myasthenia Gravis. By Philippe Gajdos, Sylvie Chevret, Bernard
Clair, Christine Tranchant, and Claude Chastang 720
Polyclonal Immunoglobulins Induce Apoptosis in a Small Proportion of
Peripheral Lymphocytes in Vitro. By Felix Bischof and Arthur Melms 727
Thymectomy in Childhood Myasthenia Gravis. By Marjorie E. Seybold .. 731
Risk of Cancer in Patients with Myasthenia Gravis. By A. Evoli, A. P.
Batocchi, P. Tonali, and M. Marciano 742
Remission of Myasthenia Gravis in Association with Unresectable, Invasive
Thymoma. By Lissette Jimenez 746
Video assisted Thoracoscopic Extended Thymectomy (VATET) in Myasthenia
Gravis: Two Year Follow up in 101 Patients and Comparison with the
Transsternal Approach. By R. Mantegazza, P. Confalonieri, C. Antozzi,
L. Novellino, M. T. Ferr6, M. Porta, G. Pezzuoli, and F. Cornelio .. 749
A Treatment Algorithm for Autoimmune Myasthenia in Adults. By John
Keesey 753
Reliability Testing of the Quantitative Myasthenia Gravis Score. By Richard
J. Barohn, Donald McIntire, Laura Herbelin, Gil I. Wolfe, Sharon
Nations, and Wilson W. Bryan 769
Oral Functions of Patients with Myasthenia Gravis. By F. G. Weunen, A. Van
Der Bilt, J. H. J. Wokke, M. W. M. Wassenberg, and I. Oudenaarde . 773
Late Onset Myasthenia Gravis: Follow up of 113 Patients Diagnosed after Age
60. By Gerhard Slesak, Arthur Melms, Friederike Gerneth, Norbert
Sommer, Robert Weissert, and Johannes Dichgans 777
Thymoma Recurrences in Myasthenia Gravis Patients. By A. Evou, A. P.
Batocchi, M. M. Lino, P. Tonali, L. Lauriola, and G. B. Doglietto . . 781
Calcium Channel and P Receptor Antagonists and Agonists in MG. By Georg
Matell, Sapko Bjelak, Iris Jonkers, Ritva Pirskanen, Jorine Van Vliet,
and Christer Swerup 785
A Treatment Algorithm for Autoimmune Myasthenia Gravis in Childhood. By
P. Ian Andrews 789
Part VII. Current Diagnosis and Treatment of
Lambert Eaton Myasthenic Syndrome
Plasma Treatment in Diseases of the Neuromuscular Junction. By F. Cornelio,
C. Antozzi, P. Confalonieri, F. Baggi, and R. Mantegazza 803
3,4 Diaminopyridine (DAP) in the Treatment of Lambert Eaton Myasthenic
Syndrome (LEMS). By Donald B. Sanders 811
A Treatment Algorithm for Lambert Eaton Myasthenic Syndrome. By John
Newsom Davis 817
Lambert Eaton Myasthenic Syndrome (LEMS): Clinical and Electrodiagnostic
Features and Response to Therapy in 59 Patients. By Richard W. Tim,
Janice M. Massey, and Donald B. Sanders 823
Wide Spectrum of Symptomatic Treatment in Lambert Eaton Myasthenic
Syndrome. By Shin J. Oh, Dae S. Kim, Kee H. Kwon, Anna Tseng,
Holly Mussell, and Gwen C. Claussen 827
Index of Contributors 833
Financial assistance was received from:
Cosponsor
• MYASTHENIA GRAVIS FOUNDATION OF AMERICA, INC. (HOST
CALIFORNIA CHAPTER)
Major Funders
• NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND
STROKE
• JACK AND JEAN CRAEMER
Supporters
• JOHN W. ALLEN, CLU, ChFC
• BAYER CORPORATION—PHARMACEUTICAL DIVISION
|
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| genre | (DE-588)1071861417 Konferenzschrift 1997 Santa Monica Calif. gnd-content |
| genre_facet | Konferenzschrift 1997 Santa Monica Calif. |
| id | DE-604.BV011882246 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:17:56Z |
| institution | BVB |
| isbn | 1573311197 1573311200 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008027635 |
| oclc_num | 455889362 |
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| owner | DE-355 DE-BY-UBR DE-12 DE-20 |
| owner_facet | DE-355 DE-BY-UBR DE-12 DE-20 |
| physical | XVII, 838 S. Ill., graph. Darst. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | New York Acad. of Sciences |
| record_format | marc |
| series | New York Academy of Sciences: Annals of the New York Academy of Sciences |
| series2 | New York Academy of Sciences: Annals of the New York Academy of Sciences |
| spelling | Myasthenia gravis and related diseases disorders of the neuromuscular junction ed. by David P. Richman New York, NY New York Acad. of Sciences 1998 XVII, 838 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier New York Academy of Sciences: Annals of the New York Academy of Sciences 841 Literaturangaben Miastenija gravis Kongresi Myasthenia gravis Congresses Neuromuscular junction Physiopathology Congresses Živčnomišični stik Fiziopatologija Kongresi Myasthenia gravis (DE-588)4075144-2 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1997 Santa Monica Calif. gnd-content Myasthenia gravis (DE-588)4075144-2 s DE-604 Richman, David P. Sonstige oth New York Academy of Sciences: Annals of the New York Academy of Sciences 841 (DE-604)BV002532608 841 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008027635&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Myasthenia gravis and related diseases disorders of the neuromuscular junction New York Academy of Sciences: Annals of the New York Academy of Sciences Miastenija gravis Kongresi Myasthenia gravis Congresses Neuromuscular junction Physiopathology Congresses Živčnomišični stik Fiziopatologija Kongresi Myasthenia gravis (DE-588)4075144-2 gnd |
| subject_GND | (DE-588)4075144-2 (DE-588)1071861417 |
| title | Myasthenia gravis and related diseases disorders of the neuromuscular junction |
| title_auth | Myasthenia gravis and related diseases disorders of the neuromuscular junction |
| title_exact_search | Myasthenia gravis and related diseases disorders of the neuromuscular junction |
| title_full | Myasthenia gravis and related diseases disorders of the neuromuscular junction ed. by David P. Richman |
| title_fullStr | Myasthenia gravis and related diseases disorders of the neuromuscular junction ed. by David P. Richman |
| title_full_unstemmed | Myasthenia gravis and related diseases disorders of the neuromuscular junction ed. by David P. Richman |
| title_short | Myasthenia gravis and related diseases |
| title_sort | myasthenia gravis and related diseases disorders of the neuromuscular junction |
| title_sub | disorders of the neuromuscular junction |
| topic | Miastenija gravis Kongresi Myasthenia gravis Congresses Neuromuscular junction Physiopathology Congresses Živčnomišični stik Fiziopatologija Kongresi Myasthenia gravis (DE-588)4075144-2 gnd |
| topic_facet | Miastenija gravis Kongresi Myasthenia gravis Congresses Neuromuscular junction Physiopathology Congresses Živčnomišični stik Fiziopatologija Kongresi Myasthenia gravis Konferenzschrift 1997 Santa Monica Calif. |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008027635&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002532608 |
| work_keys_str_mv | AT richmandavidp myastheniagravisandrelateddiseasesdisordersoftheneuromuscularjunction |