Research issues in aluminum toxicity: [workshop on ... held July 8, 1995, in Vancouver, British Columbia]
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Washington, DC. [u.a.]
Taylor & Francis
1997
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Aus: Journal of toxicology and environmental health ; 48,6 |
| Beschreibung: | XI, 256 S. graph. Darst. |
| ISBN: | 1560326484 |
Internformat
MARC
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| 245 | 1 | 0 | |a Research issues in aluminum toxicity |b [workshop on ... held July 8, 1995, in Vancouver, British Columbia] |c ed. by Robert A. Yokel ... |
| 246 | 1 | 3 | |a Aluminum toxicity |
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Datensatz im Suchindex
| _version_ | 1804126340586143744 |
|---|---|
| adam_text | CONTENTS
PREFACE xi
Chapter 1 STATUS AND FUTURE CONCERNS OF 1 !
CLINICAL AND ENVIRONMENTAL ALUMINUM J
TOXICOLOGY I
Trond Peder Flaten, Allen C. Alfrey, J. Derek j
Birchall, John Savory, and Robert A. Yokel
Environmental Aspects and Ecotoxicology 2
Aluminum Toxicity in Humans 4
Recommendations 10
References 11
Chapter 2 ALUMINUM IN WATER 17
Bruce D. LaZerte, Gary van Loon, and Bruce
Anderson
Forms of Aqueous Aluminum 18
Analytical Methods 27
Natural Waters (Soil, Ground, and Surface 29
Waters)
Drinking Water 33
Recommendations 39
References 40
Chapter 3 ECOTOXICOLOGY OF ALUMINUM TO FISH 47
AND WILDLIFE
Donald W. Sparling, T. Peter Lowe, and Peter
G. C. Campbell
Factors That Affect Availability and Toxicity of 48
Aluminum
Physiological Effects 49
Bioaccumulation of Aluminum 56
Modeling Aluminum Bioavailability 58
Assessment of Aluminum Hazards in the 60
Environment
Where Should Future Research in Ecotoxicology 62
of Aluminum Be Directed?
References 63
Chapter 4 ALUMINUM TOXICITY AND RESISTANCE IN 69
PLANTS
Leon V. Kochian and David L. Jones
I
CONTENTS vj. !
Chapter 8 WHAT WE KNOW AND WHAT WE NEED TO 151
KNOW ABOUT DEVELOPMENTAL ALUMINUM
TOXICITY
Mari S. Golub and Jose L. Domingo
Findings and Research Needs Identified from 151
Human Studies
Findings and Research Needs Identified from 154
Animal Studies
Conclusions 159
Recommendations 159
References 160
Chapter 9 OCCUPATIONAL ALUMINUM EXPOSURE AND 165
ITS HEALTH EFFECTS
Bengt Sjogren, Carl Gustaf Elinder, Anders
Iregren, Donald R. C. McLachlan, and Vesa
Riihimaki
Occupational Exposure 166
Occupational Exposure Limits 167
Toxicokinetics 167
Health Effects 171
Carcinogenicity 178
Recommendations for Future Research 179
References 179
Chapter 10 CAN THE CONTROVERSY OF THE ROLE OF 185
ALUMINUM IN ALZHEIMER S DISEASE BE
RESOLVED? WHAT ARE THE SUGGESTED
APPROACHES TO THIS CONTROVERSY AND
METHODOLOGICAL ISSUES TO BE
CONSIDERED?
John Savory, Christopher Exley, William F.
Forbes, Yue Huang, Jayant G. Joshi, Theo
Kruck, Donald R. C. McLachlan, and Ikuro
Wakayama
Is Aluminum Present at Elevated Concentrations 188
in Neurofibrillary Tangles and/or Senile
Plaques of Alzheimer s Disease?
Is Environmental Exposure to Al in Drinking 191
Water or in the Workplace a Risk Factor for
Alzheimer s Disease?
Is Desferoxamine an Effective Therapeutic Agent 195
for Alzheimer s Disease and Do the Initial
Results of Its Efficacy Implicate Al in the
Pathogenesis of the Disease?
I
viii CONTENTS
Does Al lnduced Neurodegeneration in 196
Experimental Animals Support the Hypothesis
That Al Might Play a Role in the
Pathogenesis of Alzheimer s Disease?
Does Al Promote the Deposition of Aß? 197
Does Hyperaluminemia Associated with Long 199
Term Hemodialysis Induce Neurofibrillary
Degeneration?
Conclusions 199
Recommendations 200
References 200
Chapter 11 CAN THE MECHANISMS OF ALUMINUM 207
NEUROTOXICITY BE INTEGRATED INTO A
UNIFIED SCHEME?
Michael J. Strong, Ralph M. Garruto, Jayant G.
Joshi, William R. Mundy, and Timothy J. Shafer
Aluminum Neurotoxicity with Cytoskeletal 208
Pathology
Aluminum Neurotoxicity Defined by 211
Neurochemical or Neurophysiological
Modifications in the Absence of Cytoskeletal
Pathology
Developmental Effects 213
Aluminum Transport 214
Conclusions 214
Recommendations 215
References 216
Chapter 12 PREVENTION AND TREATMENT OF 223
ALUMINUM TOXICITY INCLUDING CHELATION
THERAPY: STATUS AND RESEARCH NEEDS
Robert A. Yokel, Peter Ackrill, Ellen Burgess, J.
Philip Day, Jose L. Domingo, Trond Peder
Flaten, and John Savory
Approaches to Reduce Aluminum Accumulation 224
and Toxicity
Recommendations 234
References 235
Chapter 13 STANDARDIZATION IN BIOLOGICAL ANALYSES 241
OF ALUMINUM: WHAT ARE THE NEEDS?
Mark A. Lovell, William D. Ehmann, William R.
Markesbery, Srikumaran Melethil, Carol R. Swyt,
and Paolo F. Zatta
i
CONTENTS ix i
I
What Is Known Regarding Biological Standards 243
in General
Bulk Analysis Standards 243
Microprobe Analysis Standards 245
Conclusions 249
Primary Concerns Regarding Quantitation of Al 250
Data
Recommendations 250
References 251
INDEX 253
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| id | DE-604.BV011796491 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:15:54Z |
| institution | BVB |
| isbn | 1560326484 |
| language | English |
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| physical | XI, 256 S. graph. Darst. |
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| spelling | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] ed. by Robert A. Yokel ... Aluminum toxicity Washington, DC. [u.a.] Taylor & Francis 1997 XI, 256 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Aus: Journal of toxicology and environmental health ; 48,6 Aluminium (DE-588)4001573-7 gnd rswk-swf Toxizität (DE-588)4078372-8 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1996 Vancouver British Columbia gnd-content Aluminium (DE-588)4001573-7 s Toxizität (DE-588)4078372-8 s DE-604 Yokel, Robert A. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007963818&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] Aluminium (DE-588)4001573-7 gnd Toxizität (DE-588)4078372-8 gnd |
| subject_GND | (DE-588)4001573-7 (DE-588)4078372-8 (DE-588)1071861417 |
| title | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] |
| title_alt | Aluminum toxicity |
| title_auth | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] |
| title_exact_search | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] |
| title_full | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] ed. by Robert A. Yokel ... |
| title_fullStr | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] ed. by Robert A. Yokel ... |
| title_full_unstemmed | Research issues in aluminum toxicity [workshop on ... held July 8, 1995, in Vancouver, British Columbia] ed. by Robert A. Yokel ... |
| title_short | Research issues in aluminum toxicity |
| title_sort | research issues in aluminum toxicity workshop on held july 8 1995 in vancouver british columbia |
| title_sub | [workshop on ... held July 8, 1995, in Vancouver, British Columbia] |
| topic | Aluminium (DE-588)4001573-7 gnd Toxizität (DE-588)4078372-8 gnd |
| topic_facet | Aluminium Toxizität Konferenzschrift 1996 Vancouver British Columbia |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007963818&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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