Lipids and syndromes of insulin resistance: from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic]
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Format: | Tagungsbericht Buch |
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Sprache: | English |
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New York, NY
New York Acad. of Sciences
1997
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Schriftenreihe: | Annals of the New York Academy of Sciences
827 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XII, 582 S. Ill., zahlr. graph. Darst. |
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adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 827
September 20, 1997
LIPIDS AND SYNDROMES
OF INSULIN RESISTANCE
FROM MOLECULAR BIOLOGY TO CLINICAL MEDICINE0
Editors and Conference Organizers
I. Klimes, S. M. Haffner, E. Sebokova, B. V. Howard, and L. H. Storlien
CONTENTS
Preface. By Iwar Klimes and Elena Sebokova xi
Keynote Address: Progress in Population Analyses of the Insulin
Resistance Syndrome. By Steven M. Haffner 1
Part I. Animal Models of the Insulin Resistance Syndrome
Hypertension and the Insulin Resistance Syndrome of Rats: Are They
Related? By Iwar Klimes and Elena Sebokova 13
Obesity Genes and Insulin Resistance Syndrome. By E. Bowie Kahle,
Rudolph L. Leibel, Dirk W. Domaschko, Sam G. Raney, and
K. Traci Mann 35
Development of Obesity and Insulin Resistance in the Israeli Sand Rat
(Psammomys obesus): Does Leptin Play a Role? By G. R. Collier,
A. de Silva, A. Sanigorski, K. Walder, A. Yamamoto, and
P. ZlMMET 50
Diabetes and Hypertension in Rodent Models. By Ingrid Kloting,
Sabine Berg, Peter Kovacs, Birger Voigt, Lutz Vogt,
and Siegfried Schmidt 64
Insulin Resistance Syndrome in Mice Deficient in Insulin Receptor
Substrate 1. By Hiroyuki Tamemoto, Kazuyuki Tobe,
Toshihisa Yamauchi, Yasuo Terauchi, Yasushi Kaburagi,
and Takashi Kadowaki 85
° The papers in this volume were presented at the Third International Smolenice Insulin Sym¬
posium on Lipids and Syndromes of Insulin Resistance: From Molecular Biology to Clinical Medi¬
cine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic,
and organized by the Diabetes and Nutrition Research Group of the Institute of Experimental Endo¬
crinology, Slovak Academy of Sciences, Bratislava, Slovak Republic, in collaboration with the Slovak
Diabetes and Endocrine Societies; the Department of Medicine, Division of Clinical Epidemiology,
University of Texas Health Science Center, San Antonio, Texas; the Department of Biomedical
Science, University of Wbllongong, New South Wales, Australia; and the Medlantic Research Insti¬
tute, Washington, District of Columbia.
WOK.1W Rats: A Potential Animal Model of the Insulin Resistance
Syndrome. By Peter Kovacs, Birger Voigt, Sabine Berg,
Lutz Vogt, and Ingrid Kloting 94
Part II. Molecular Biology of Syndromes of Insulin Resistance
Lipid Transport Genes and Their Relation to the Syndrome of Insulin
Resistance. By David J. Galton, Qiuping Zhang, Elisabeth Cavallero,
Julian Cavanna, Andrea Kay, Aline Charles, Sylvie Braschi,
Leon Perlemuter, and Bernard Jacotot 100
Progress in Determining the Genes for Hypertension, Insulin Resistance,
and Dyslipidemia. By Mark Caulfield, Pierre Marc Bouloux,
and Patricia Munroe 110
Hyperinsulinemia and Sympathoadrenal System Activity in the Rat.
By Richard Kvetnansky, Milan Rusnak, Daniela Gasperikova,
Jana Jelokova, Stefan Zorad, Iua Vietor, Karel Pacak,
Elena Sebokova, Ladislav Macho, Esther L. Sabban, and
Iwar Klimes 118
Is a Mutation of the p3 Adrenergic Receptor Gene Related to Non Insulin
dependent Diabetes Mellitus and Juvenile Hypertension in the Czech
Population? By B. Bendlova, I. Mazura, J. Vcelak, J. Perusicova,
D. Palyzova, I. Klimes, and E. Sebokova 135
Glucose Transport and Insulin Signaling in Rat Muscle and Adipose
Tissue: Effect of Lipid Availability. By D. Gasperikova, I. Klimes,
T. Kolter, P. Bohov, A. Maassen, J. Eckel, M. T. Clandinin,
and E. Sebokova 144
Cafestol (a Coffee Lipid) Decreases Uptake of Low Density Lipoprotein
(LDL) in Human Skin Fibroblasts and Liver Cells. By A. C. Rustan,
B. Halvorsen, T. Ranheim, and C. A. Drevon 158
High Fructose Feeding Enhances Erythrocyte Carbonic Anhydrase 1 mRNA
Levels in Rat. By K. K. Gambhir, P. Oates, M. Verma, S. Temam,
and W. Cheatham 163
Pharmacological Treatment and Mechanisms of Insulin Resistance: Impact
on Vascular Smooth Muscle Cells, Blood Pressure, and Lipids.
By Willa A. Hsueh and Ronald E. Law 170
Part III. Role of Lipids in Diseases of Insulin Resistance
Fatty Acid Regulation of Gene Expression: Its Role in Fuel Partitioning and
Insulin Resistance. By Steven D. Clarke, Rebecca Baillie,
Donald B. Jump, and Manabu T. Nakamura 178
Impact of Dietary Fatty Acid Composition on Insulin Action at the Nucleus.
By Nana A. Gletsu and M. Thomas Clandinin 188
Molecular and Cellular Determinants of Triglyceride Availability.
By E. Sebokova and I. Klimes 200
Dietary Fatty Acids, Insulin Resistance, and Diabetes.
By Barbara V. Howard 215
Lipid Abnormalities in Muscle of Insulin resistant Rodents: The Malonyl
CoA Hypothesis. By N. B. Ruderman, A. K. Saha, D. Vavvas,
S. J. Heydrick, and T. G. Kurowski 221
Pharmacological Strategies for Reduction of Lipid Availability. By James E.
Foley, Robert C. Anderson, Philip A. Bell, Bryan F. Burkey,
Rhonda O. Deems, Christopher de Souza, and Beth E. Dunning ... 231
Effect of Oral Antidiabetics and Insulin on Lipids and Coronary Heart
Disease in Non Insulin dependent Diabetes Mellitus. By M. Hanefeld,
T. Temelkova Kurktschiev, and C. Kohler 246
Relationships between Fatty Acid Composition and Insulin induced
Oxidizability of Low Density Lipoproteins in Healthy Men.
By T. Pelikanova, E. Tvrzicka, L. Kazdova, and. A. Zak 269
Small Dense Low Density Lipoprotein (LDL) in Non Insulin dependent
Diabetes Mellitus (NIDDM): Impact of Hypertriglyceridemia.
By T. Temelkova Kurktschiev, M. Hanefeld, and W. Leonhardt .... 279
Part IV. Dietary Fats in Diseases of Insulin Resistance
Does Dietary Fat Influence Insulin Action? By L. H. Storlien,
A. D. Kriketos, A. B. Jenkins, L. A. Baur, D. A. Pan, L. C. Tapsell,
and G. D. Calvert 287
Monounsaturated and Marine co 3 Fatty Acids in NIDDM Patients.
By A. A. Rivellese 302
Omega 3 and Omega 6 Fatty Acids in the Insulin Resistance Syndrome:
Lipid and Lipoprotein Metabolism and Atherosclerosis.
By A. C. Rustan, M. S. Nenseter, and C. A. Drevon 310
Omega 6/Omega 3 Fatty Acid Ratio and Trans Fatty Acids in Non Insulin
dependent Diabetes Mellitus. By Artemis P. Simopoulos 327
Dietary Fats and Hypertension: Focus on Fish Oil. By Peter R. C. Howe 339
Postprandial Triglyceride High Response and the Metabolic Syndrome.
By J. Schrezenmeir, S. Fenselau, I. Keppler, J. Abel,
B. Orth, Ch. Laue, W. Sturmer, U. Fauth, M. Halmagyi,
and W. Marz 353
Evaluation of an Omega 3 Fatty Acid Supplement in Diabetics with
Microalbuminuria. By Yvonne K. Lungershausen, Peter R. C. Howe,
Peter M. Clifton, Christopher R. T. Hughes, Pat Phillips,
John J. Graham, and David W. Thomas 369
Paleodiet and Its Relation to Atherosclerosis. By J. Lietava, M. Thurzo,
and A. Dukat 382
Part V. Energy Balance, Lipids, and Obesity
Passive Overconsumption: Fat Intake and Short Term Energy Balance.
By John E. Blundell and Jennie I. Macdiarmid 392
Dietary Fats and Thermogenesis. By A. Tremblay and C. Bouchard 408
Fat Metabolism in the Predisposition to Obesity. By Arne Astrup,
Anne Raben, Benjamin Buemann, and ScSren Toubro 417
Fat and Energy Balance. By Michael J. Pagliassotti, Ellis C. Gayles,
and James O. Hill 431
Recent Advances in the Pharmacological Control of Energy Balance and
Body Weight. By Richard L. Atkinson 449
Fat Substitutes and Energy Balance. By John C. Peters 461
Nonesterified Fatty Acid Regulation of Lipid and Glucose Oxidation in the
Obese. By Sarah E. King, Janet M. Bryson, Louise A. Baur,
Soji Swaraj, and Ian D. Caterson 476
Part VI. Poster Papers
Nuclear AU trans Retinoic Acid Receptors in Liver of Rats with
Diet induced Insulin Resistance. By J. Brtko, E. Sebokova,
D. Gasperikova, I. Klimes, S. Hudecova, and J. Bransova 480
Diet induced Insulin Resistance Is Associated with Decreased Activity of
Type I Iodothyronine 5 Deiodinase in Rat Liver. By J. Bransova,
A. Brtkova, E. Sebokova, I. Klimes, P. Langer, and J. Brtko 485
Insulin and Catecholamines Act at Different Stages of Rat Liver Regeneration.
By J. Knopp, L. Macho, M. Fickova, s. Zorad, R. Kvetnansky,
and I. Jaroscakova 489
Fatty Acid Composition in Fractions of Structural and Storage Lipids in
Liver and Skeletal Muscle of Hereditary Hypertriglyceridemic Rats.
By Pavol Bohov, Elena Sebokova, Daniela Gasperikova,
Pavel Langer, and Iwar Klimes 494
Increased Adipose Tissue Lipolysis in a Hypertriglyceridemic Rat Line.
By A. Vrana and L. Kazdova 510
Structural Changes in the Aorta of the Hereditary Hypertriglyceridemic Rat.
By Frantisek Kristek, Sona Edelsteinova, Elena Sebokova,
Jan Kyselovic, and Iwar Klimes 514
Increased Lipoprotein Oxidability and Aortic Lipid Peroxidation in
an Experimental Model of Insulin Resistance Syndrome.
By Ludmila Kazdova, Ales Zak, and Antoni n Vrana 521
Phenotype and Genotype Comparison of Hereditary Hypertriglyceridemic
(hHTG) and Brown Norway (BN) Rats: Identification of Quantitative
Trait Loci (QTLs) for the Insulin Resistance Syndrome.
By Peter Kovacs, Nilesh J. Samani, Elena Sebokova, Birger Voigt,
Daniela Gasperikova, Daniela Jezova, Richard Kvetnansky,
David Lodwick, Ingrid Kloting, and Iwar Klimes 526
Insulin Resistance in Adipocytes of SHR Rats. By M. Fickova, S. Zorad,
J. Kunes, M. Rusnak, and L. Macho 532
Disproportionate Increase of Fatty Acid Binding Proteins in the Livers of
Obese Diabetic Psammomys obesus. By P. Lewandowski,
D. Cameron Smith, K. Moulton, K. Walder, A. Sanigorski, and
G. R. Collier 536
Partial Characterization of Insulin Resistance in Adipose Tissue of
Monosodium Glutamate induced Obese Rats. By S. Zorad, L. Macho,
D. Jezova, and M. Fickova 541
Biguanide Effects on Insulin Signaling. By Emmanuelle Meuillet,
Nicolas Wiernsperger, Pierre Hubert, and Gerard Cremel 546
Effect of the High Fat Diet on the Calcium Channels in Rat Myocardium.
By I. Minarovic, R. Vojtko, E. Sebokova, I. Klimes, and I. Zahradnik 550
The Effect of Fasting and Vitamin E on Insulin Action in Obese Type 2
Diabetes Mellitus. By J. Skrha, G. Sindelka, and J. Hilgertova 556
The Effect of Hyperlipidemia on Serum Fatty Acid Composition in Type 2
Diabetics. By Pavol Bohov, Viliam Balaz, Elena Sebokova, and
Iwar Klimes 561
High Lipid Levels in Slovak Rural Population: Consequence of Thyroid
Dysfunction or Nutritional Status? By P. Langer, E. Hanzen,
M. Tajtakova, Z. Putz, A. Kreze, E. Sebokova, P. Bohov,
D. Gasperikova, M. Huckova, and I. Klimes 568
Activity of Antioxidant Enzymes during Hyperglycemia and Hypoglycemia
in Healthy Subjects. By J. KoSka, D. Syrova, P. BLAzfcEK, M. Marko,
D. J. Grna, R. Kvetnansky, and M. Vigas 575
Index of Contributors 581
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spelling | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] ed. by I. Klimeš ... New York, NY New York Acad. of Sciences 1997 XII, 582 S. Ill., zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 827 Insulinresistenz (DE-588)4234712-9 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1996 Smolenice gnd-content Insulinresistenz (DE-588)4234712-9 s DE-604 Klimeš, Iwar Sonstige oth International Smolenice Insulin Symposium 3 1996 Smolenice Sonstige (DE-588)1302305-6 oth Annals of the New York Academy of Sciences 827 (DE-604)BV002532608 827 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007887143&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] Annals of the New York Academy of Sciences Insulinresistenz (DE-588)4234712-9 gnd |
subject_GND | (DE-588)4234712-9 (DE-588)1071861417 |
title | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] |
title_auth | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] |
title_exact_search | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] |
title_full | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] ed. by I. Klimeš ... |
title_fullStr | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] ed. by I. Klimeš ... |
title_full_unstemmed | Lipids and syndromes of insulin resistance from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] ed. by I. Klimeš ... |
title_short | Lipids and syndromes of insulin resistance |
title_sort | lipids and syndromes of insulin resistance from molecular biology to clinical medicine the papers in this volume were presented at the third international smolenice insulin symposium on lipids and syndromes of insulin resistance from molecular biology to clinical medicine which was held on august 28 to september 1 1996 in smolenice castle slovak republic |
title_sub | from molecular biology to clinical medicine ; [the papers in this volume were presented at the Third International Smolenice Insulin Symposium on Lipids and Syndromes of Insulin Resistance: from Molecular Biology to Clinical Medicine, which was held on August 28 to September 1, 1996, in Smolenice Castle, Slovak Republic] |
topic | Insulinresistenz (DE-588)4234712-9 gnd |
topic_facet | Insulinresistenz Konferenzschrift 1996 Smolenice |
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