Prognostic indicators for cancer:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1997
|
| Schriftenreihe: | Surgical oncology clinics of North America
6,3 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 415 - 665 S. Ill., graph. Darst. |
Internformat
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| adam_text | PROGNOSTIC INI lt I IONS FOR CANCER
CONTENTS
Foreword ix
Blake Cady
Preface xi
Noel Weidner
Pathologic Prognostic Factors for Patients with Breast
Carcinoma: Which Factors Are Important 415
Noel Weidner, Blake Cady, and William H. Goodson III
Current technologies can identify subsets of patients who are at
greater risk for developing recurrent carcinoma. This article pres¬
ents conventional and generally accepted pathologic features of
breast carcinoma that allow breast carcinoma patients to be placed
into low risk or high risk categories for recurrence free or overall
survival. Also, the role of flow cytometry, estrogen progesterone
receptor measurement, tumor angiogenesis, and selection onco
protein expression, such as c erbB2, are reviewed.
Prognostic Factors in Colorectal Carcinomas 463
Arnold B. Gelb and Theodore R. Schrock
Colorectal carcinoma remains a leading cause of cancer morbidity
and mortality. Various clinical signs and pathologic factors have
been shown to have a bearing on a patient s prognosis. Some of
these factors, such as extent of disease (stage) and histologic grade,
are generally accepted, while others, primarily biologic and mo¬
lecular markers, have been proposed recently and remain contro¬
versial. The authors describe both more established and newly pro¬
posed variables, reviewing multivariate analyses to examine their
relative importance. The recommendations of the Association of
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA
VOLUME 6 • NUMBER 3 • JULY 1997 V
Directors of Anatomic and Surgical Pathology for the reporting of
colorectal carcinomas are presented.
Gastric Cancer 495
Kimberly S. Kirkwood, Lev M. Khitin, and Kenneth W. Barwick
The recent shift in the population from patients presenting with
gastric cancer to patients presenting with early stage lesions has
led to renewed interest in identifying prognostic factors for this
type of tumor. Conveniently for surgeons, prognostic factors can
be divided into groups that are assessed preoperatively, intraoper
atively, and postoperatively. Despite the explosion of interest in
genetic and molecular markers for gastric cancer, the feature best
correlated with patient survival continues to be tumor stage at the
time of diagnosis.
Prognostic Factors in Esophageal Cancer 515
Marco G. Patti and David Owen
Clinical and pathologic factors relevant to the prognosis of esoph¬
ageal cancer are reviewed in this article. Clinical factors discussed
include endoscopic, radiologic, and surgical findings. The impor¬
tance of Barrett s esophagus and the role of endoscopic screening
in the diagnosis of dysplasia and the prevention of adenocarcinoma
are evaluated. Pathologic factors include the traditional ones of
tumor type, stage, and grade as well as newer tumor markers re¬
lated to DNA content, rate of cell proliferation, oncogenes, and
tumor suppressor genes.
Prognostic Factors in Pancreatic Carcinoma 533
Carolyn C. Compton and Sean J. Mulvihill
Pancreatic cancer is a relatively common malignancy. Its gravity is
underscored by the low overall cure rates. A number of clinical,
pathologic, and molecular factors have been identified that predict
survival of patients with this neoplasm. These factors are reviewed
and analyzed.
Prognostic Factors in Thyroid Carcinoma 555
Patrick A. Treseler and Orlo H. Clark
Thyroid carcinomas range from the most indolent to the most ag¬
gressive human malignancies. A variety of clinical and pathologic
factors can be used to help predict behavior and determine appro¬
priate therapy. New molecular biologic techniques show promise
in further refining the assessment of prognosis in thyroid cancer
patients.
Vi CONTENTS
Prognostic Factors in Malignant Melanoma 599
Mohammed Kashani Sabet, Stanley P.L. Leong,
and Richard Sagebiel
The clinical spectrum and biologic behavior of melanoma are het¬
erogeneous. Several clinical factors may include sex, location, and
age. Histologic prognostic factors may include tumor type, tumor
thickness, and mitotic index in relationship to the primary tumor.
With respect to metastatic melanoma, the prognostic factors may
include lymph node status, number of lymph nodes, and extracap
sular extension. Cytogenetic and molecular determinants of pro¬
gression of melanoma may aid the current prognostic factors when
they are established more firmly. Current surgical treatment is de¬
termined by the clinical and histologic factors.
Prognostic Factors for Cutaneous Squamous Cell and Basal
Cell Carcinoma: Determinants of Risk of Recurrence,
Metastasis, and Development of Subsequent Skin Cancers 625
Sarah K. Barksdale, Nicholas O Connor, and Raymond Barnhill
Squamous cell carcinoma and basal cell carcinoma are the most
common cancers in humans. This article discusses general prog¬
nostic factors for these nonmelanocytic skin cancers. Anatomic and
histologic considerations for both carcinomas are also presented.
Prognostic Factors and Management of Carcinomas
of the Gallbladder and Extrahepatic Bile Ducts 639
Randall G. Lee and Jean Emond
Cancers of the biliary tract are uncommon but aggressive malig¬
nancies that pose difficult problems in diagnosis and management.
Long term survival with these cancers is limited by their propen¬
sity for local invasion, so that pathologic stage becomes a major
prognostic factor, and by their ability to cause biliary obstruction
and sepsis and interfere with hepatic function. In selected patients,
surgical resection offers the possibility of cure, but effective palli¬
ation is often the principal goal of treatment. Radiologic and en
doscopic modalities thus often play a major role in patient man¬
agement.
Index 661
Subscription Information Inside back cover
CONTENTS Vli
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| indexdate | 2024-07-09T18:14:04Z |
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| language | English |
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| physical | XI, 415 - 665 S. Ill., graph. Darst. |
| publishDate | 1997 |
| publishDateSearch | 1997 |
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| publisher | Saunders |
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| series | Surgical oncology clinics of North America |
| series2 | Surgical oncology clinics of North America |
| spelling | Prognostic indicators for cancer Noel Weidner, guest ed. Philadelphia [u.a.] Saunders 1997 XI, 415 - 665 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Surgical oncology clinics of North America 6,3 Tumeurs - Chirurgie Neoplasms diagnosis Krankheitsverlauf (DE-588)4208496-9 gnd rswk-swf Therapieerfolg (DE-588)4126073-9 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Krankheitsverlauf (DE-588)4208496-9 s DE-604 Therapieerfolg (DE-588)4126073-9 s Weidner, Noel Sonstige oth Surgical oncology clinics of North America 6,3 (DE-604)BV007071205 6,3 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007880665&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Prognostic indicators for cancer Surgical oncology clinics of North America Tumeurs - Chirurgie Neoplasms diagnosis Krankheitsverlauf (DE-588)4208496-9 gnd Therapieerfolg (DE-588)4126073-9 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| subject_GND | (DE-588)4208496-9 (DE-588)4126073-9 (DE-588)4073781-0 (DE-588)4143413-4 |
| title | Prognostic indicators for cancer |
| title_auth | Prognostic indicators for cancer |
| title_exact_search | Prognostic indicators for cancer |
| title_full | Prognostic indicators for cancer Noel Weidner, guest ed. |
| title_fullStr | Prognostic indicators for cancer Noel Weidner, guest ed. |
| title_full_unstemmed | Prognostic indicators for cancer Noel Weidner, guest ed. |
| title_short | Prognostic indicators for cancer |
| title_sort | prognostic indicators for cancer |
| topic | Tumeurs - Chirurgie Neoplasms diagnosis Krankheitsverlauf (DE-588)4208496-9 gnd Therapieerfolg (DE-588)4126073-9 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| topic_facet | Tumeurs - Chirurgie Neoplasms diagnosis Krankheitsverlauf Therapieerfolg Krebs Medizin Aufsatzsammlung |
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