Lipid polymorphism and membrane properties:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego [u.a.]
Acad. Press
1997
|
| Schriftenreihe: | Current topics in membranes
44 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVIII, 568 S. Ill., graph. Darst. |
| ISBN: | 0121533441 |
Internformat
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| 245 | 1 | 0 | |a Lipid polymorphism and membrane properties |c ed. by Richard M. Epand |
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| 300 | |a XVIII, 568 S. |b Ill., graph. Darst. | ||
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Datensatz im Suchindex
| _version_ | 1804126177945714688 |
|---|---|
| adam_text | Contents
Contributors xi
Preface xv
Previous Volumes in Series xvii
PART I Characterization of Nonlamellar Structures
CHAPTER I The Cubic Phases of Lipids
Vittorio Luzzati, Herve Delacroix, Annette Gulik, Tadeusz
Gulik Kryzwicki, Paolo Mariani, and Rodolfo Vargas
I. Introduction 3
II. Structure Analysis 7
III. Chemical Properties 9
IV. Structure Representations 12
V. Orderly Disposal of Short Range Conformational
Disorder: The Chaotic Zones 15
VI. Biological Implications 19
References 21
CHAPTER 2 Membrane Lipid Molecular Structure
and Polymorphism
Ruthven N. A. H. Lewis, David A. Mannock, and
Ronald N. McElhaney
I. Introduction 25
II. Nonlamellar Forming Lipids of Biological Membranes:
General Properties 27
III. Molecular Structure and Nonlamellar Phase Behavior:
Theoretical and Mechanistic Considerations 31
IV. Molecular Structure and Nonlamellar Phase Behavior:
Experimental Observations 39
V. Concluding Remarks 77
References 81
V
i ;
vi Contents
CHAPTER 3 NMR Studies of Membrane Lipid Properties
Robin L. Thurmond and Goran Lindblom
I. Introduction 104
II. Theory 109
III. The La Phase 117
IV. The Hn Phase 131
V. Other Phases 139
VI. Relaxation 142
VII. Translational Diffusion Studied by NMR 143
VIII. Conclusions and Possible Biological Relevance 152
References 155
CHAPTER 4 Hydration, Curvature, and Bending Elasticity of
Phospholipid Monolayers
R. P. Rand and V. A. Parsegian
I. Introduction 167
II. Using Osmotic Stress 171
III. Probing the Dimensions and Energetics of These
Structures 171
IV. Measuring Monolayer Curvature and Bending
Modulus 178
V. Unpredictability of Curvature and Phases 179
VI. Effects of Other Kinds of Lipids on the Phase, the
Curvature, and the Hydration of the Lipid
Assemblies 180
VII. Summary 186
References 187
PART II Perturbation of Bilayer Properties CHAPTER 5 Phase Behavior of Membranes Containing
Bioactive Lipids
Juan C. Gomez Fernandez, Jose Villalain, and
Francisco J. Aranda
I. Introduction 193
II. a Tocopherol in Membranes 194
HI. Modulation of Lipid Phase Behavior by the Presence of
Diacylglycerols 209
Contents vii
IV. Concluding Remarks 226
References 228
CHAPTER 6 Modulation of Lipid Polymorphism by Peptides
Richard M. Epand
I. Introduction 237
II. Factors Affecting Peptide Modulation of Lipid
Polymorphism 239
III. Examples 243
IV. Reciprocal Effects of Class A and L Amphipathic
Helices 247
V. Conclusions 248
References 249
PART III Protein Activity and Membrane Properties
CHAPTER 7 Membrane Properties and the Activation of Protein
Kinase C and Phospholipase A2
Raphael Zidovetzki
I. Introduction 255
II. Biological Effects of DAGS 256
III. Membrane Structure and PKC Activity 257
IV. Membrane Structure and PLA2 Activity 259
V. Nonbilayer Lipid Phases 260
VI. Effect of PC PS Phase Separation on PKC Activity 266
VII. Lateral Phase Separation of the Bilayers on the Regions
of Different Fluidities 267
VIII. Transverse Bilayer Perturbations 269
IX. Conclusions 271
References 273
CHAPTER 8 Influence of Nonlamellar Forming
Lipids on Rhodopsin
Michael F. Brown
I. Introduction 286
II. The Visual System 290
III. Role of Membrane Lipids in the Visual Process 303
viii Contents
IV. Properties of the Membrane Lipid Bilayer in Comparison
to the Photochemical Function of Rhodopsin 333
V. Membrane Deformation Energy, Curvature Frustration,
and Rhodopsin Function 343
References 349
PART IV Membrane Fusion CHAPTER 9 Liposome Fusion
Austin L. Bailey and Pieter R. Cullis
I. Introduction 359
II. Lipid Polymorphism 360
III. Lipid Polymorphism and Fusion 364
IV. Lipid Asymmetry and Fusion 368
V. Conclusion 369
References 371
CHAPTER 10 Membrane Fusion Intermediates
Philip L. Yeagle
I. Introduction 375
II. Curvature 377
III. Relevancy of Curvature of SUV and Hn to Membrane
Fusion 386
IV. Role of Nonlamellar Intermediates in Vesicle
Fusion 388
V. Role of Nonlamellar Intermediates in Viral Fusion 394
VI. Summary 397
References 397
CHAPTER 11 Morphology of Membrane Fusion
Koert N. J. Burger
I. Introduction 403
II. Technical Considerations 405
HI. Morphology of Biomembrane Fusion 412
IV. Membrane Fusion Intermediates 416
V. Fusogenic Lipids and Model Membrane Fusion 420
VI. Type II Lipids and Biomembrane Fusion 427
VII. Role of Proteins in Biomembrane Fusion 431
Contents ix
VIII. Conclusions and Prospects 436
References 438
PART V Biological Systems CHAPTER 12 Drug Delivery Applications
Frank L. Sorgi and Leaf Huang
I. Introduction 449
II. pH Sensitive Liposomes 452
III. Target Sensitive Liposomes 454
IV. Photosensitive Liposomes 455
V. Cationic Liposomes 456
VI. Future Considerations 468
VII. Conclusion 469
References 471
CHAPTER 13 Phospholipid Structure and
Escherichia coli Membranes
Ben de Kruijff, J. Antoinette Killian, Anton G. Rietveld, and
Ron Kusters
I. Introduction 477
II. The E. coli Membranes and Their Phospholipids 478
III. Phase Preference of Individual E. coli
Phospholipids 483
IV. Lipid Organization of E. coli Membranes and Derived
Lipid Dispersions 490
V. Effect of Membrane Active Additives on Lipid
Organization 497
VI. Functional Aspects 500
References 513
CHAPTER 14 Regulation of Lipid Syntheses in
Acholeplasma laidlawii
Ake Wieslander and Olof P. Karlsson
I. Introduction 517
II. Molecular Biology of Acholeplasma laidawii 519
x Contents
III. Membrane Polar Lipid Composition 520
IV. Regulation of Membrane Lipids 522
V. Comparison with Other Membranes 532
VI. Conclusions 534
References 535
CHAPTER 15 Curvature Stress and Biomembrane Function
Sek Wen Hui
I. Curvature Stress in Biomembranes 541
II. Curvature Stress and Membrane Functions 545
III. Possible Mechanisms of Functional Control by Curvature
Stress 556
References 559
Index 565
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| spelling | Lipid polymorphism and membrane properties ed. by Richard M. Epand San Diego [u.a.] Acad. Press 1997 XVIII, 568 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Current topics in membranes 44 Couche biomoléculaire pica Fusion membranaire pica Lipiden gtt Lipides des membranes ram Lipides membranaires - Physiologie Membranen gtt Membranes (biologie) ram Polymorfisme gtt Membrane Lipids physiology Membrane lipids Biomembran (DE-588)4006884-5 gnd rswk-swf Lipide (DE-588)4035873-2 gnd rswk-swf Phospholipidmembran (DE-588)4174401-9 gnd rswk-swf Polymorphismus (DE-588)4130554-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Lipide (DE-588)4035873-2 s Biomembran (DE-588)4006884-5 s Polymorphismus (DE-588)4130554-1 s DE-604 Phospholipidmembran (DE-588)4174401-9 s Epand, Richard M. 1937- Sonstige (DE-588)172720915 oth Current topics in membranes 44 (DE-604)BV036839511 44 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007848257&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lipid polymorphism and membrane properties Current topics in membranes Couche biomoléculaire pica Fusion membranaire pica Lipiden gtt Lipides des membranes ram Lipides membranaires - Physiologie Membranen gtt Membranes (biologie) ram Polymorfisme gtt Membrane Lipids physiology Membrane lipids Biomembran (DE-588)4006884-5 gnd Lipide (DE-588)4035873-2 gnd Phospholipidmembran (DE-588)4174401-9 gnd Polymorphismus (DE-588)4130554-1 gnd |
| subject_GND | (DE-588)4006884-5 (DE-588)4035873-2 (DE-588)4174401-9 (DE-588)4130554-1 (DE-588)4143413-4 |
| title | Lipid polymorphism and membrane properties |
| title_auth | Lipid polymorphism and membrane properties |
| title_exact_search | Lipid polymorphism and membrane properties |
| title_full | Lipid polymorphism and membrane properties ed. by Richard M. Epand |
| title_fullStr | Lipid polymorphism and membrane properties ed. by Richard M. Epand |
| title_full_unstemmed | Lipid polymorphism and membrane properties ed. by Richard M. Epand |
| title_short | Lipid polymorphism and membrane properties |
| title_sort | lipid polymorphism and membrane properties |
| topic | Couche biomoléculaire pica Fusion membranaire pica Lipiden gtt Lipides des membranes ram Lipides membranaires - Physiologie Membranen gtt Membranes (biologie) ram Polymorfisme gtt Membrane Lipids physiology Membrane lipids Biomembran (DE-588)4006884-5 gnd Lipide (DE-588)4035873-2 gnd Phospholipidmembran (DE-588)4174401-9 gnd Polymorphismus (DE-588)4130554-1 gnd |
| topic_facet | Couche biomoléculaire Fusion membranaire Lipiden Lipides des membranes Lipides membranaires - Physiologie Membranen Membranes (biologie) Polymorfisme Membrane Lipids physiology Membrane lipids Biomembran Lipide Phospholipidmembran Polymorphismus Aufsatzsammlung |
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