Papillomaviruses in human cancer: the role of E6 and E7 oncoproteins
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | German |
| Veröffentlicht: |
New York ; Berlin ; Heidelberg ; London ; Paris ; Tokyo ; Hong K
Springer
1997
Austin Landes |
| Schriftenreihe: | Molecular biology intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | 173 S. Ill., graph. Darst. |
| ISBN: | 3540630805 1570594562 |
Internformat
MARC
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| 245 | 1 | 0 | |a Papillomaviruses in human cancer |b the role of E6 and E7 oncoproteins |c Massimo Tommasino |
| 264 | 1 | |a New York ; Berlin ; Heidelberg ; London ; Paris ; Tokyo ; Hong K |b Springer |c 1997 | |
| 264 | 1 | |a Austin |b Landes | |
| 300 | |a 173 S. |b Ill., graph. Darst. | ||
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| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Molecular biology intelligence unit | |
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Cell Transformation, Neoplastic | |
| 650 | 4 | |a Neoplasms |x etiology | |
| 650 | 4 | |a Oncogene Proteins, Viral | |
| 650 | 4 | |a Oncogenes | |
| 650 | 4 | |a Oncogenic viruses | |
| 650 | 4 | |a Papillomaviridae | |
| 650 | 4 | |a Papillomavirus Infections |x complications | |
| 650 | 4 | |a Papillomaviruses | |
| 650 | 4 | |a Viral Vaccines | |
| 650 | 4 | |a Viral carcinogenesis | |
| 650 | 4 | |a Viral proteins | |
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Datensatz im Suchindex
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| adam_text |
i, CONTENTS =ji
1. Human Papillomaviruses and Cancer: A Retrospective 1
Harald zur Hansen
1.1. The Origins of Papillomavirus Research 1
1.2. A Rabbit Papillomavirus System Causing Cancer 2
' 1.3. Papillomavirus Infections in Cattle 4
1.4. Several Human Papillomavirus Types 5
2. Regulation of E6 and E7 Oncogene Transcription 25
: Frank Rosl and Elisabeth Schwarz
I 2.1. Introduction 25
I 2.2. In Vivo Expression of the E6 and E7 Oncogenes 27
! 2.3. Viral and Cellular Factors for E6/E7 Oncogene
Transcription 29
2.4. The Consequences of Integration on Viral Gene
Expression 50
2.5. The Role of the Genetic Background: Transcriptional
Regulation of Viral Gene Expression in Nonmalignant
and Malignant Cells 54
3. E6 Protein 71
Felix Hoppe Seyler and Martin Scheffner
3.1. Introduction 71
3.2. Expression and Structural Aspects 72
3.3. Immortalizing and Transforming Activities 73
3.4. Mechanisms of Immortalization 74
3.5. Role of E6 in the Viral Life Cycle 89
3.6. Therapeutic Perspectives 90
4. E7 Protein 103
Massimo Tommasino and Pidder Jansen Diirr
4.1. Introduction 103
4.2. Domain Structure of the Molecule 103
4.3. Subcellular Localization 109
4.4. Immortalizing and Transforming Activities Ill
4.5. Cellular Pathways Targeted by E7 113
4.6. E7 Protein and Apoptosis 124
4.7. Conclusion 125
5. Immunological Aspects of the E6 and E7 Oncogenes:
Tools for Diagnosis and Therapeutic Intervention 137
Ingrid Jochmus and Lutz Gissmann
, 5.1. Introduction 137
I 5.2. Humoral Immune Response Against E6 and E7 138
5.3. Cellular Immune Responses Against E6 and E7 147
5.4. HPV E6 and E7 as Potential Therapeutic Vaccines 156
Index 167 |
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV011578692 |
| callnumber-first | R - Medicine |
| callnumber-label | RC268 |
| callnumber-raw | RC268.57 |
| callnumber-search | RC268.57 |
| callnumber-sort | RC 3268.57 |
| callnumber-subject | RC - Internal Medicine |
| classification_rvk | XH 4900 |
| ctrlnum | (OCoLC)36807667 (DE-599)BVBBV011578692 |
| dewey-full | 616.99/4071 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99/4071 |
| dewey-search | 616.99/4071 |
| dewey-sort | 3616.99 44071 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV011578692 |
| illustrated | Illustrated |
| indexdate | 2025-01-10T17:11:22Z |
| institution | BVB |
| isbn | 3540630805 1570594562 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007797174 |
| oclc_num | 36807667 |
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| owner | DE-355 DE-BY-UBR DE-12 |
| owner_facet | DE-355 DE-BY-UBR DE-12 |
| physical | 173 S. Ill., graph. Darst. |
| publishDate | 1997 |
| publishDateSearch | 1997 |
| publishDateSort | 1997 |
| publisher | Springer Landes |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spelling | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins Massimo Tommasino New York ; Berlin ; Heidelberg ; London ; Paris ; Tokyo ; Hong K Springer 1997 Austin Landes 173 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Literaturangaben Cell Transformation, Neoplastic Neoplasms etiology Oncogene Proteins, Viral Oncogenes Oncogenic viruses Papillomaviridae Papillomavirus Infections complications Papillomaviruses Viral Vaccines Viral carcinogenesis Viral proteins Papillomaviren (DE-588)4219886-0 gnd rswk-swf Papillomatosis (DE-588)4193515-9 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Carcinogenese (DE-588)4069853-1 gnd rswk-swf Onkoproteine (DE-588)4318742-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Papillomaviren (DE-588)4219886-0 s Onkoproteine (DE-588)4318742-0 s DE-604 Papillomatosis (DE-588)4193515-9 s Carcinogenese (DE-588)4069853-1 s Tommasino, Massimo Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007797174&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins Cell Transformation, Neoplastic Neoplasms etiology Oncogene Proteins, Viral Oncogenes Oncogenic viruses Papillomaviridae Papillomavirus Infections complications Papillomaviruses Viral Vaccines Viral carcinogenesis Viral proteins Papillomaviren (DE-588)4219886-0 gnd Papillomatosis (DE-588)4193515-9 gnd Krebs Medizin (DE-588)4073781-0 gnd Carcinogenese (DE-588)4069853-1 gnd Onkoproteine (DE-588)4318742-0 gnd |
| subject_GND | (DE-588)4219886-0 (DE-588)4193515-9 (DE-588)4073781-0 (DE-588)4069853-1 (DE-588)4318742-0 (DE-588)4143413-4 |
| title | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins |
| title_auth | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins |
| title_exact_search | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins |
| title_full | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins Massimo Tommasino |
| title_fullStr | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins Massimo Tommasino |
| title_full_unstemmed | Papillomaviruses in human cancer the role of E6 and E7 oncoproteins Massimo Tommasino |
| title_short | Papillomaviruses in human cancer |
| title_sort | papillomaviruses in human cancer the role of e6 and e7 oncoproteins |
| title_sub | the role of E6 and E7 oncoproteins |
| topic | Cell Transformation, Neoplastic Neoplasms etiology Oncogene Proteins, Viral Oncogenes Oncogenic viruses Papillomaviridae Papillomavirus Infections complications Papillomaviruses Viral Vaccines Viral carcinogenesis Viral proteins Papillomaviren (DE-588)4219886-0 gnd Papillomatosis (DE-588)4193515-9 gnd Krebs Medizin (DE-588)4073781-0 gnd Carcinogenese (DE-588)4069853-1 gnd Onkoproteine (DE-588)4318742-0 gnd |
| topic_facet | Cell Transformation, Neoplastic Neoplasms etiology Oncogene Proteins, Viral Oncogenes Oncogenic viruses Papillomaviridae Papillomavirus Infections complications Papillomaviruses Viral Vaccines Viral carcinogenesis Viral proteins Papillomaviren Papillomatosis Krebs Medizin Carcinogenese Onkoproteine Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007797174&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT tommasinomassimo papillomavirusesinhumancancertheroleofe6ande7oncoproteins |