Acquired neuromuscular diseases:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1997
|
| Schriftenreihe: | Neurologic clinics
15,3 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | IX S., S. 481 - 736 Ill., graph. Darst. |
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| 245 | 1 | 0 | |a Acquired neuromuscular diseases |c Rahman Pourmand guest ed. |
| 264 | 1 | |a Philadelphia [u.a.] |b Saunders |c 1997 | |
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| 650 | 2 | |a Maladies neuromusculaires | |
| 650 | 7 | |a Neuromusculaire aandoeningen |2 gtt | |
| 650 | 4 | |a Neuromuscular Diseases | |
| 650 | 4 | |a Neuromuscular diseases | |
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Datensatz im Suchindex
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|---|---|
| adam_text | ACQUIRED NEUROMUSCULAR DISEASES
CONTENTS
Preface ix
Rahman Pourmand, MD
Acquired Motor Neuron Disorders 481
Mark A. Ross
The acquired motor neuron disorders are a heterogeneous group
of conditions in which motor neuron degeneration or dysfunction
produces the predominant manifestation of weakness, while the
sensory system is clinically spared. The disorders most commonly
seen in clinical practice are amyotrophic lateral sclerosis, late man¬
ifestations of poliomyelitis, and lower motor neuron syndromes,
including motor neuropathy. Less often, acquired motor neuron
disorders may complicate metabolic, toxic, or systemic disorders.
The pathogenesis of most acquired motor neuron disorders is
poorly understood, and treatment is mainly supportive; however
clues to understanding the pathogenesis of amyotrophic lateral
sclerosis are emerging, and new pharmacologic therapies are avail¬
able. There is a growing sense of hope that combinations of drugs
that are currently being tested may impact the survival of amyo¬
trophic lateral sclerosis.
Acquired Peripheral Neuropathy 501
Colin H. Chalk
This article reviews the acquired causes of polyneuropathy other
than diabetic and acute onset neuropathies. The author gives a gen¬
eral method to simplify the diagnosis of chronic polyneuropathy.
The acquired polyneuropathies are discussed under four main
headings: metabolic disorders, toxic or deficiency states, infections,
and immune mediated. Recent advances in therapy are empha¬
sized, and some illustrative case histories are provided.
Acute Peripheral Neuropathy in Adults 529
Robert M. Pascuzzi and James D. Fleck
Acute paralysis in adults has an extensive assortment of etiologies.
Guillian Barre syndrome is the most common cause of acute neu
NEUROLOGIC CLINICS
ropathy in adults. This review emphasizes pathophysiology, clin¬
ical features, differential diagnosis, and a practical approach to the
laboratory work up for patients with suspected Guillian Barre syn¬
drome. The current status of immunotherapy is reviewed.
Diagnosis and Management of Common Compression
and Entrapment Neuropathies 549
William W. Campbell
The most common focal neuropathies are carpal tunnel syndrome,
ulnar neuropathy at the elbow, and peroneal neuropathy at the
fibular head, but many other focal neuropathies, due to external
compression or entrapment, may occur. Rational management de¬
pends on accurate localization; a thorough understanding of the
basic anatomy, pathology, and pathophysiology helps in dealing
with the vagaries of clinical presentation and electrodiagnostic
evaluation. The differential diagnosis includes musculoskeletal
conditions, plexopathies, radiculopathies, and occasionally, central
nervous system dysfunction. Some focal neuropathies are an ac¬
centuation of a more generalized process, and a complex interplay
of focal and diffuse pathology can arise.
Diabetic Neuropathy 569
Rahman Pourmand
The most common form of diabetic neuropathy is chronic, distal
symmetrical sensorimotor, or predominantly sensory neuropathy;
the latter is invariably associated with some degree of autonomic
dysfunction. There are, however, other neuropathic patterns in di¬
abetes mellitus that are uncommon but are important to recognize,
since they may mimic many other non neurologic diseases. This
article discusses a variety of forms of mononeuropathies and dia¬
betic proximal motor neuropathy, commonly known as diabetic
amyotropy.
Acquired Myasthenia Gravis 577
Janice M. Massey
Myasthenia gravis, an antibody mediated disorder of neuromus
cular transmission that produces clinical weakness, may be ocular
or generalized. Clinical diagnostic evaluation may be supple¬
mented by electrophysiologic studies and antibody testing. Ther¬
apeutic options, including anticholinesterase inhibitors, immuno
suppressive agents, plasmapheresis and thymectomy, are tailored
for the individual patient. This article emphasizes the key aspects
of the clinical evaluation, diagnosis, and therapy.
Paraneoplastic Neuromuscular Syndromes 597
Kerry H. Levin
Although paraneoplastic syndromes are rare, a number of well
defined, neuromuscular paraneoplastic syndromes have been de¬
scribed and their pathophysiology listed. Many different malig¬
nancies have been associated with these syndromes, but small cell
lung cancer is the most common. Features shared by these
conditions include onset of the underlying malignancy, rapid pro¬
gression, severe disability, and the potential for some improve¬
ment, owing to treatment of the cancer. This article discusses Lam¬
bert Eaton myasthenic syndrome, motor neuron disorders,
peripheral neuropathies, and disorders of continuous muscle fiber
activity, such as Stiffman syndrome.
Idiopathic Inflammatory Myopathies 615
Anthony A. Amato and Richard J. Barohn
Dermatomyositis, polymyositis, and inclusion body myositis are
the major categories of idiopathic inflammatory myopathy. These
inflammatory myopathies are distinct clinically, histologically, and
pathogenically. Features of dermatomyositis and polymyositis can
overlap with those of other autoimmune connective tissue diseases.
In this article, the authors review the characteristic features of these
myopathies, update the recent developments in this area, and pro¬
vide a framework for treatment.
Myoglobinuria, Malignant Hyperthermia, Neuroleptic
Malignant Syndrome and Serotonin Syndrome 649
Tulio E. Bertorini
This article presents an overview of the causes and manifestations
of myoglobinuria and provides criteria for its diagnosis and man¬
agement. The article also reviews neuroleptic malignant syndrome,
malignant hyperthermia, and serotonin syndrome, all of which
could cause rhabdomyolysis and myoglobinuria.
Endocrine Neuromyopathies 673
Angela Anagnos, Robert L. Ruff, and Henry J. Kaminski
The myopathies associated with endocrine disorders range in clin¬
ical presentation from the relatively nonspecific pattern of proxi¬
mal muscle weakness of glucocorticoid excess states to specific
presentations of contractions produced in tetany. All endocrine
neuromyopathies emphasize the role of skeletal muscle in protein,
carbohydrate, and electrolyte metabolism. Hormonal abnormali¬
ties tend to compromise muscle force generation by indirect effects
on muscle function. The recognition and effective treatment of all
these disorders require the identification of the underlying hor¬
monal imbalances and awareness of general medical problems pro¬
duced by the endocrine disorders.
Muscle Pain, Fatigue, and Fasiculations 697
John C. Kincaid
This article discusses muscle pain, fatigue, and fasiculations. Mus¬
cle pain and fatigue are common problems in general medicine and
in neurology, while fasiculations raise concern about a potentially
ominous disease. The author reviews the conditions that cause pain
and similar conditions arising from nonmuscular soft tissues. The
article includes a general evaluation to be used for each of these
clinical problems.
Toxic Myopathies 711
Kristi K. George and Rahman Pourmand
Toxic myopathies may occur with a variety of prescribed medica¬
tions, illicit drug abuse, or other toxins. The article discusses an
overview of some of the compounds that may cause myopathy, the
clinical and laboratory features, histology, mechanisms of action,
and potential risk factors of myopathy. The ability to recognize
these syndromes is essential to avoid unnecessary tests and to
avoid delay in treatment, especially in critically ill patients or pa¬
tients with other neuromuscular diseases.
Index 731
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| series | Neurologic clinics |
| series2 | Neurologic clinics |
| spelling | Acquired neuromuscular diseases Rahman Pourmand guest ed. Philadelphia [u.a.] Saunders 1997 IX S., S. 481 - 736 Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neurologic clinics 15,3 Maladies neuromusculaires Neuromusculaire aandoeningen gtt Neuromuscular Diseases Neuromuscular diseases Neuromuskuläre Krankheit (DE-588)4075332-3 gnd rswk-swf Sekundärkrankheit (DE-588)4131705-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Neuromuskuläre Krankheit (DE-588)4075332-3 s Sekundärkrankheit (DE-588)4131705-1 s DE-604 Pourmand, Rahman Sonstige (DE-588)138117306 oth Neurologic clinics 15,3 (DE-604)BV000003008 15,3 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007748259&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Acquired neuromuscular diseases Neurologic clinics Maladies neuromusculaires Neuromusculaire aandoeningen gtt Neuromuscular Diseases Neuromuscular diseases Neuromuskuläre Krankheit (DE-588)4075332-3 gnd Sekundärkrankheit (DE-588)4131705-1 gnd |
| subject_GND | (DE-588)4075332-3 (DE-588)4131705-1 (DE-588)4143413-4 |
| title | Acquired neuromuscular diseases |
| title_auth | Acquired neuromuscular diseases |
| title_exact_search | Acquired neuromuscular diseases |
| title_full | Acquired neuromuscular diseases Rahman Pourmand guest ed. |
| title_fullStr | Acquired neuromuscular diseases Rahman Pourmand guest ed. |
| title_full_unstemmed | Acquired neuromuscular diseases Rahman Pourmand guest ed. |
| title_short | Acquired neuromuscular diseases |
| title_sort | acquired neuromuscular diseases |
| topic | Maladies neuromusculaires Neuromusculaire aandoeningen gtt Neuromuscular Diseases Neuromuscular diseases Neuromuskuläre Krankheit (DE-588)4075332-3 gnd Sekundärkrankheit (DE-588)4131705-1 gnd |
| topic_facet | Maladies neuromusculaires Neuromusculaire aandoeningen Neuromuscular Diseases Neuromuscular diseases Neuromuskuläre Krankheit Sekundärkrankheit Aufsatzsammlung |
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