HLA and disease - the molecular basis: proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Copenhagen
Munksgaard
1997
|
| Schriftenreihe: | Alfred Benzon Symposium: Alfred Benzon Symposium
40 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 440 S. graph. Darst. |
| ISBN: | 8716119428 |
Internformat
MARC
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| 245 | 1 | 0 | |a HLA and disease - the molecular basis |b proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 |c ed. Arne Svejgaard ... |
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| 650 | 4 | |a HLA histocompatibility antigens |v Congresses | |
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Datensatz im Suchindex
| _version_ | 1804125947812642816 |
|---|---|
| adam_text | List of participants
Introduction 13
I. HLA molecules: genes and structures
Organization of the human MHC by John Trowsdale 21
Discussion 33
The class I and class II proteins of the human major histocompatibility
complex by Jack L. Strominger Don C. Wiley 38
Structural basis of cellular immune recognition by I. A. Wilson, K. C.
Garcia, M. Degano, R. L. Stanfield, Z. Zeng, B. Segelke, E. A. Stu
ra, A. R. Castano, D. A. Jewell, A. Brunmark, M. R. Jackson,
P. A. Peterson L. Teyton 46
Discussion 58
Regulation and expression of novel MHC class I genes and molecules by
Thomas Spies, Seiamak Bahram, Stefan Bauer Veronika Groh . . 61
Discussion 68
II. Antigen presentation
Viruses use stealth technology to escape from the host immune system by
Emmanuel J. H. J. Wiertz, Siddhartha Mukherjee Hidde L.
Ploegh 73
Discussion 87
Function and polymorphism of MHC genes in class I antigen processing
by John J. Monaco, Dipankar Nandi, Kate Marusina, Mohan Iyer
Haibo Jiang 91
Discussion 96
Assembly, transport and peptide loading of MHC class II molecules by
Peter Cresswell, B. Arunachalam, Lisa K. Denzin, Craig Ham¬
mond Ninette Robbins 100
Discussion 109
6
Invariant chain regulation of MHC class II function in the secretory and
endocytic pathways by Ronald N. Germain, Elizabeth K. Bikoff,
Juan S. Bonifacino, Flora Castellino, Ricai Han, Michael S. j
Marks, Paola Romagnoli Guangming Zhong 114 i
Discussion 127 ¦
III. Peptide binding
MHC class I binding motifs: an unbiased quantitative approach to motif
definition by Anette Stryhn, Lars 0stergaard Pedersen, Tina Rom
me, Charlotte Bisgaard Holm, Arne Holm Soren Buus 133
Discussion 145
The biochemical and cellular basis of peptide selection during antigen pro¬
cessing by Emil R. Unanue, Christopher A. Nelson Nicholas J.
Viner 148
Discussion 158
Transport of immunogens into the MHC class I and II pathways by a
peptide from HIV tat by Jonathan Rothbard, Dewey Kim, Dennis
Mitchell, Dirk Bockstedt, Lawrence Fong, Gary Nolan, C. Garri¬
son Fathman Edgar Engleman 161
Discussion 172
IV T CELL RECOGNITION
Ligand recognition by gamma delta T cells by Yueh hsiu Chien, Hansjorg
Schild, Nasim Mavadatt, Edwin Rock Mark Davis 179
Discussion 189
Biological and chemical aspects of T cell receptor mediated recognition by
M. M. Davis, D. S. Lyons, J. D. Altman, J. Hamp, J. J. Boniface,
B. Arden Y. Chien 193
Discussion 201
The selection of the T cell receptor repertoire by self peptides in the thymus
by Derek B. Sant Angelo, Beth E. Cohen, Thea Brabb, P. Greg
Waterbury, Joan Goverman Charles A. Janeway, Jr 204
Discussion 214
7
Interactions of T cell receptor V/? elements with staphylococcal superanti
gens by John Kappler, Haruo Kozono, Janice Clements, Francis
Crawford, Janice White, Michele Pelanne Philippa Marrack . . 217
Discussion 226
T cell recognition of altered peptide ligands by Gilbert J. Kersh Paul
M. Allen 231
Discussion 241
V. Thymic selection and tolerance
Thymic selection analyzed in mutant mice by Harald von Boehmer . . . 247
Discussion 255
The structure and specificity of T cells selected by a single MHC/peptide
combination by Philippa Marrack, Leszek Ignatowicz, David Park¬
er, Chih Pin Liu John Kappler 258
Discussion 267
Reversal of peripheral T cell tolerance: implications for autoimmunity by
Bernd Arnold, Judith Alferink, Andreas Limmer, Anna Tafuri
Gunter J. Hammerling 272
Discussion 279
The Tec family tyrosine kinases BTK and ITK in lymphocyte development
and activation by Bo Dupont, Avery August, Joyce M. C. Teng, Ali
Sadra Philip D. King 284
Discussion 295
VI. HLA AND DISEASE
Associations between HLA and disease with notes on additional associ¬
ations between a new immunogenetic marker and rheumatoid arthritis
by Arne Svejgaard, Lars Fugger, Peter Garred, Hans O. Madsen
Lars P. Ryder 301
Discussion 314
HLA in infectious disease by Andrew McMichael 317
Discussion 326
HLA class I and class II alleles involved in the regulation of immune re¬
sponse to HBs antigen by Takehiko Sasazuki 331
8
VII. Pathogenesis of autoimmune disorders
The role of MHC class II molecules in susceptibility and resistance to type
I diabetes mellitus by Hugh McDevitt 337
Discussion 345
MHC and non MHC genetic influences on the BDC2.5 TCR transgenic
model of insulin dependent diabetes by Antonio Gonzalez, Fred
Luhder, Christophe Benoist Diane Mathis 349
Discussion 359
The molecular basis of the HLA association in celiac disease: a model for
other HLA associated diseases by Ludvig M. Sollid, Bente H. Johan
SEN, KNUT E. A. LUNDIN, 0YVIND MOLBERG, HELGE SCOTT, HANS Sj6
strom, Christopher J. Thorpe, Frode Vartdal Erik Thorsby . . . 362
Discussion 373
HLA DR4 and human CD4 transgenic mice as a potential model for rheu¬
matoid arthritis by Lars Fugger, Jonathan B. Rothbard Grete
Sonderstrup McDevitt 378
Discussion 387
VIII. Towards therapy of autoimmune disorders
Autoimmune arthritis by Rikard Holmdahl 393
Discussion 407
Activation of myelin basic protein specific T cells by viral peptides by Kai
WUCHERPFENNIG 409
Discussion 418
Mechanisms of oral tolerance and treatment of autoimmune diseases by
Howard L. Weiner 423
Discussion 437
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| genre_facet | Konferenzschrift 1996 Kopenhagen |
| id | DE-604.BV011432518 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:09:39Z |
| institution | BVB |
| isbn | 8716119428 |
| language | English |
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| physical | 440 S. graph. Darst. |
| publishDate | 1997 |
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| series | Alfred Benzon Symposium: Alfred Benzon Symposium |
| series2 | Alfred Benzon Symposium: Alfred Benzon Symposium |
| spelling | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 ed. Arne Svejgaard ... Copenhagen Munksgaard 1997 440 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Alfred Benzon Symposium: Alfred Benzon Symposium 40 Autoimmune Diseases immunology Congresses HLA Antigens Congresses HLA histocompatibility antigens Congresses Immunologic diseases Congresses Immunology Congresses HLA (DE-588)4160063-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1996 Kopenhagen gnd-content HLA (DE-588)4160063-0 s DE-604 Svejgaard, Arne Sonstige oth Alfred Benzon Symposium: Alfred Benzon Symposium 40 (DE-604)BV000000824 40 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007688099&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 Alfred Benzon Symposium: Alfred Benzon Symposium Autoimmune Diseases immunology Congresses HLA Antigens Congresses HLA histocompatibility antigens Congresses Immunologic diseases Congresses Immunology Congresses HLA (DE-588)4160063-0 gnd |
| subject_GND | (DE-588)4160063-0 (DE-588)1071861417 |
| title | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 |
| title_auth | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 |
| title_exact_search | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 |
| title_full | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 ed. Arne Svejgaard ... |
| title_fullStr | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 ed. Arne Svejgaard ... |
| title_full_unstemmed | HLA and disease - the molecular basis proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 ed. Arne Svejgaard ... |
| title_short | HLA and disease - the molecular basis |
| title_sort | hla and disease the molecular basis proceedings of a symposium held at the royal danish academy of sciences and letters august 4 8 1996 |
| title_sub | proceedings of a symposium held at the Royal Danish Academy of Sciences and Letters, August 4 - 8, 1996 |
| topic | Autoimmune Diseases immunology Congresses HLA Antigens Congresses HLA histocompatibility antigens Congresses Immunologic diseases Congresses Immunology Congresses HLA (DE-588)4160063-0 gnd |
| topic_facet | Autoimmune Diseases immunology Congresses HLA Antigens Congresses HLA histocompatibility antigens Congresses Immunologic diseases Congresses Immunology Congresses HLA Konferenzschrift 1996 Kopenhagen |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007688099&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000000824 |
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