Brain attack:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1997
|
| Schriftenreihe: | Neurosurgery clinics of North America
8,2 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII S., S. 135 - 285 Ill., graph. Darst. |
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| 245 | 1 | 0 | |a Brain attack |c Warren R. Selman ..., guest ed. |
| 264 | 1 | |a Philadelphia [u.a.] |b Saunders |c 1997 | |
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| 490 | 1 | |a Neurosurgery clinics of North America |v 8,2 | |
| 650 | 2 | |a Encéphalopathie ischémique - Thérapeutique | |
| 650 | 2 | |a Encéphalopathie ischémique - prévention et contrôle | |
| 650 | 4 | |a Brain Ischemia |x prevention & control | |
| 650 | 4 | |a Brain Ischemia |x therapy | |
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Datensatz im Suchindex
| _version_ | 1804125872742989824 |
|---|---|
| adam_text | BRAIN ATTACK
CONTENTS
Preface xiii
Warren R. Selman and W. David Lust
Brain Attack: Introduction 135
Roberto C. Heros, Paul J. Camarata, and Richard E. Latchaw
In today s medical community, the term brain attack is used in two ways.
It is used as a synonym for stroke, and also as a reference to an educational
and logistic campaign aimed at earlier recognition and treatment of stroke.
This article presents an introduction to both uses of the phrase brain
attack, and focuses on the need for a brain attack campaign.
Nutrient Consumption and Metabolic Perturbations 145
Joseph C. LaManna and W. David Lust
The brain is entirely dependent on a continual supply of nutrients for the
production of energy and the maintenance of function. Brain attack is a
good example of a condition where the loss of blood flow and the consequent
deprivation of nutrients can be devastating in terms of both structure and
function. The unique metabolic characteristics of the brain make it more
susceptible than most other organs of the body to nutrient restriction and
starvation. In addition, changes occur during ischemia that compromise
nutrient consumption even with reperfusion. Clearly, improving the out¬
come following brain attack will require a restoration of nutrient consump¬
tion to meet the relatively high energetic demands of the brain, and novel
interventions to offset any metabolic lesions induced by the insult or reperfu¬
sion injury.
Prevention of Primary Event: Ischemic Stroke Risk Detection and
Reduction 165
Anthony J. Orencia and Jose Biller
Risk detection and reduction methods for persons at high risk of ischemic
stroke involve screening and identification of risk factors. Population based
health surveys affirm a persistent dilemma in the inability to reduce the
NEUROSURGERY CLINICS OF NORTH AMERICA
VOLUME 8 • NUMBER 2 • APRIL 1997 V ii
frequency of ischemic stroke risk factors, such as hypertension, cigarette
smoking, obesity, and physical inactivity levels. These alarming trends indi¬
cate that mass approach policies and programs need to be implemented
or rethought to attain maximum levels of benefit in ischemic stroke risk
reduction for the entire community.
Clinical Monitoring of Early Pathophysiologic Events 179
Robert W. Tarr
Stroke is the most prevalent life threatening neurologic disease. The
opportunity to intervene in the acute setting with the use of thrombolytics
or neuroprotective agents has led to an evolving interest in obtaining
physiologic data points during the acute event. Several imaging techniques
are available that can provide pertinent information during the acute
phase of an ischemic episode. Some of these techniques, such as diffusion
weighted and perfusion weighted MR imaging, show exciting promise
for defining the ischemic penumbra zone, which is the target of acute inter¬
vention.
Acute Therapeutic Interventions: Free Radical Scavengers and
Antioxidants 195
Edward D. Hall
Evidence suggesting a role of oxygen radical induced lipid peroxidation in
global and focal ischemic brain damage is reviewed, and the potential for
treatment of these conditions with antioxidant compounds is highlighted.
This article also presents a basis for appreciating the pharmacologic mecha¬
nisms by which oxygen radical damage can be inhibited.
Acute Therapeutic Intervention: Antithrombotic and Antiplatelet
Aggregating Drugs 207
Harold P. Adams, Jr and Enrique C. Leira
Although antiplatelet and anticoagulant drugs are of proven usefulness
in the prevention of stroke among high risk persons, their value in
improving outcome after acute ischemic stroke has not been established.
Potentially effective drugs include heparin, low molecular weight heparins
and heparinoids, aspirin, and the new glycoprotein lib/Ilia platelet
receptor antagonists. Clinical trials are testing these drugs, and the role
of emergent administration of anticoagulant or antiplatelet drugs in the
acute treatment of persons with ischemic stroke should be clarified in
the near future.
Thrombolysis For Acute Ischemic Stroke 219
Dennis M.D. Landis, Robert W. Tarr, and Warren R. Selman
The use of thrombolytic agents to restore cerebral blood flow is one of the
most notable advances in the treatment of ischemic stroke. This article
reviews thrombolytic therapy, its limitations, and the techniques by which
thrombolytic agents can be delivered.
viii contents :
Acute Surgical Therapeutic Interventions in Stroke Patients 227
Christopher M. Loftus
Surgical presence in the treatment of acute stroke patients is becoming
increasingly aggressive. This article presents the current standards for stroke
surgery in the acute setting, and defines those patient groups that represent
appropriate candidates for such intervention.
Brain Attack: The Emergent Management of Hypertensive Hemorrhage 237
Christopher L. Taylor, Warren R. Selman, and Robert A. Ratcheson
Intracerebral hemorrhage (ICH) accounts for one half of stroke related
deaths, with hypertensive hemorrhage being the primary etiology. The
evolution of minimally invasive devices for removal of ICHs, and the earlier
delivery of patients for medical attention may have a great impact on the
management of hypertensive hemorrhage.
Enhancing Recovery From Ischemic Stroke 245
David S. Geldmacher
Despite the intense efforts devoted to preventing and aborting cerebral
ischemia, some individuals will continue to have completed infarctions.
Failure of prevention or intervention does not, however, preclude therapeu¬
tic approaches to enhance recovery. This article will review working defini¬
tions applicable to the care and rehabilitation of patients after ischemic
stroke. Significant, preliminary research on how adrenergic systems may
alter the recovery from cerebral damage is also reviewed. Beneficial effects
of agents which promote adrenergic function, and the adverse effects of
monoaminergic blockade in animals and humans are discussed. The poten¬
tial role of synaptic mechanisms like long term potentiation is reviewed in
the context of motor recovery. These factors are likely to have important
implications in the future acute care of patients with completed stroke.
Treatment of Embolic Stroke as a Medical Emergency: Implications in
a Managed Care Environment 253
Charles F. Lanzieri
Encouraging innovations should be a concern of the providers/gatekeepers
of health care if lower health care costs are to become a reality. Controlled
prices and improper incentives will dramatically slow innovation in Ameri¬
can medicine. For the vertically integrated health care system providing
capitated coverage, the aggressive treatment of stroke is a sound finan¬
cial decision.
Special Articles
Clinical Epidemiology of Stroke 265
Daryl W. Thompson and Anthony J. Furlan
The effect of stroke as a major health issue in the United States is well
established. Well designed epidemiologic studies have contributed impor¬
tant information about the natural history of stroke and its associated risk
CONTENTS ix
factors. These cerebrovascular profiles have provided the foundation for
many of the current ischemic stroke trials, but the cause and prevention of
the hemorrhagic subtypes remain elusive.
Neurocritical Care for Acute Ischemic Stroke 271
Ernst Hund, Armin Grau, and Werner Hacke
Treatment strategies for acute ischemic stroke include general and specific
measures. The rationale for these strategies is discussed, and the current
practice in the acute phase of ischemic stroke is presented. Special attention
is given to the patient requiring intensive care.
Index 283
Subscription Information Inside back cover
x CONTENTS
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| physical | XIII S., S. 135 - 285 Ill., graph. Darst. |
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| series | Neurosurgery clinics of North America |
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| spelling | Brain attack Warren R. Selman ..., guest ed. Philadelphia [u.a.] Saunders 1997 XIII S., S. 135 - 285 Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neurosurgery clinics of North America 8,2 Encéphalopathie ischémique - Thérapeutique Encéphalopathie ischémique - prévention et contrôle Brain Ischemia prevention & control Brain Ischemia therapy Schlaganfall (DE-588)4052588-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Schlaganfall (DE-588)4052588-0 s DE-604 Selman, Warren R. Sonstige oth Neurosurgery clinics of North America 8,2 (DE-604)BV002758938 8,2 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007635670&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title | Brain attack |
| title_auth | Brain attack |
| title_exact_search | Brain attack |
| title_full | Brain attack Warren R. Selman ..., guest ed. |
| title_fullStr | Brain attack Warren R. Selman ..., guest ed. |
| title_full_unstemmed | Brain attack Warren R. Selman ..., guest ed. |
| title_short | Brain attack |
| title_sort | brain attack |
| topic | Encéphalopathie ischémique - Thérapeutique Encéphalopathie ischémique - prévention et contrôle Brain Ischemia prevention & control Brain Ischemia therapy Schlaganfall (DE-588)4052588-0 gnd |
| topic_facet | Encéphalopathie ischémique - Thérapeutique Encéphalopathie ischémique - prévention et contrôle Brain Ischemia prevention & control Brain Ischemia therapy Schlaganfall Aufsatzsammlung |
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