Contrast agents for body MR imaging:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1996
|
| Schriftenreihe: | Magnetic resonance imaging clinics of North America
4,1 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | IX, 189 S. Ill., graph. Darst. |
Internformat
MARC
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| 245 | 1 | 0 | |a Contrast agents for body MR imaging |c Neil M. Rofsky, guest ed. |
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| 300 | |a IX, 189 S. |b Ill., graph. Darst. | ||
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| 490 | 1 | |a Magnetic resonance imaging clinics of North America |v 4,1 | |
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| 650 | 2 | |a Technique d'imagerie par résonance magnétique nucléaire | |
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Datensatz im Suchindex
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| adam_text | CONTRAST AGENTS FOR BODY MR IMAGING
CONTENTS
Foreword xi
Jeffrey C. Weinreb
Preface xiii
Neil M. Rofsky
Basic Principles of MR Contrast Agents 1
Gerald L. Wolf and Juha T. Halavaara
Although familiar for CNS enhancement, contrast agents for body MR appli¬
cations are both similar and different. This short summary emphasizes the
basics of tissue relaxation and the added influences of paramagnetic or
superparamagnetic pharmaceuticals. An overview of safety and cost consid¬
erations is included.
Body MR Angiography with Gadolinium Contrast Agents 11
Martin R. Prince
This article describes the theory behind using gadolinium chelates for arte¬
rial imaging. Techniques are presented to alleviate some of the intrinsic
deficiencies of conventional MR angiography that result in motion artifact.
Examples are presented to illustrate how gadolinium MR angiography can
be performed on the aorta and other large arteries.
Gastrointestinal Contrast Agents for MR Imaging 25
Jeffrey J. Brown
This article reviews the current status of gastrointestinal contrast agents
being developed for MR imaging. The need for a bowel marker in MR
imaging and the characteristics of an ideal agent are discussed. The major
enteric MR agents are classified and reviewed with emphasis on their relative
advantages and disadvantages. Finally, the future role of these agents is con¬
sidered.
Liver I: Currently Available Gadolinium Chelates 37
Donald G. Mitchell
To use currently available gadolinium chelates most effectively, the liver
should be imaged repetitively after contrast agent injection during hepatic
arterial, portal vein, and delayed phases. Metastases usually demonstrate
early as transient enhancement, which is often rim shaped. Cavernous hem
angiomas, however, demonstrate gradual clump by clump enhancement.
Detection of hepatocellular carcinomas can be improved by use of dynamic
scanning techniques. These and other principles of the use of currently
available gadolinium chelates are reviewed in this article.
Liver II: Iron Oxide Based Reticuloendothelial Contrast Agents for
MR Imaging: Clinical Review 53
Jan Petersein, Sanjay Saini, and Ralph Weissleder
Iron oxide based compounds are a new class of MR contrast agents that have
a wide range of clinical applications. The biodistribution and subsequent
influence on the MR image depends on the particle size. Iron oxides can
be used to increase contrast to noise ratio, facilitating the visibility of focal
liver lesions. Other applications include blood pool imaging and targeting
the reticuloendothelial system and cell surface receptors.
Liver III: Gadolinium Based Hepatobiliary Contrast Agents (Gd
EOB DTPA and Gd BOPTA/Dimeg) 61
Andrea Giovagnoni and Enrico Pad
Gd EOB DTPA and Gd BOPTA are MR contrast agents targeted to hepato
cytes. Both are modified from the Gd DTPA structure and generate increased
signal intensity within the hepatic parenchyma. Due to the hepatobiliary
uptake, the contrast dynamics offer a broad temporal range during which
effective liver contrast is maintained, quite different from that which is
available from extracellular contrast agents. Preliminary data suggest an
improved capacity for lesion detection and that rapid imaging, early after
administration of these agents, may allow for lesion characterization as well.
Mangafodipir Trisodium Injection (Mn DPDP): A Contrast Agent for
Abdominal MR Imaging 73
Neil M. Rofsky and James P. Earls
Mangafodipir trisodium (Mn DPDP) is one of several recently developed
targeted hepatobiliary agents. Contrast to noise measurements have shown
favorable results for Mn DPDP enhanced MR as compared with nonen
hanced Tl and T2 weighted images. An improved capability for lesion
detection and the ability to characterize tumors of hepatocellular origin
have been demonstrated. The prolonged enhancement obtained with Mn
DPDP provides an extended window of time during which effective contrast
is maintained as compared with traditional extracellular contrast agents.
This report details the experimental and initial clinical experience with Mn
DPDP enhanced MR imaging of the abdomen.
Contrast Enhanced MR Imaging of the Pancreas 87
Ute Kettritz and Richard C. Semelka
Recent MR techniques such as breath hold imaging, fat suppression, and
dynamic imaging after intravenous administration of gadolinium chelates
have reduced artifacts in the abdomen, resulting in an increased role of MR
imaging in the evaluation of pancreatic disease. The extracellular contrast
agent gadolinium chelate has been shown to enhance normal pancreatic
tissue in a homogeneous fashion. Contrast between normal pancreatic tissue
and tumor tissue on Tl weighted images may be improved after administra¬
tion of gadolinium. Because of the lesser vascularization of pancreatic ductal
cancers as compared to the normal glandular tissue, the differences in signal
intensity are often greatest in the capillary phase immediately after contrast
administration. In addition, the hypervascular nature of islet cell tumors
results in good definition of primary tumor and liver metastases on immedi¬
ate post gadolinium images.
i Contrast Enhanced MR Imaging of the Kidneys and Adrenal Glands 101
Rahel A. Huch Boni, Jorg F. Debatin, and Gabriel P. Krestin
Technical developments including motion artifact compensation and the
use of paramagnetic contrast agents have substantially improved the perfor¬
mance of MR imaging of the kidneys and adrenal glands. MR imaging
allows one to assess morphologic alterations of the kidneys as well as
perfusion and functional derangements. MR imaging is the best noninvasive
method for distinction of benign from malignant adrenal masses.
Contrast Enhanced MR Imaging of Gynecologic Disorders 133
Eric K. Outwater
Although standard MR imaging techniques can provide most of the impor¬
tant diagnostic information needed for studies of the female pelvis, intrave¬
nous contrast and bowel contrast agents can provide critical ancillary infor¬
mation in selected patients. Imaging techniques and diagnostic principles
related to the use of these agents for gynecologic disorders are discussed.
Contrast Enhanced MR Imaging of the Bladder and Prostate 153
Evan S. Siegelman and Mitchell D. Schnall
The staging of both bladder and prostate carcinoma is important to deter¬
mine appropriate therapy. Routine clinical staging of these tumors, however,
has only limited accuracy. This article reviews the literature on contrast
enhanced MR of both bladder and prostate cancer, including technique
optimization and potential benefits of contrast enhanced studies.
Targeted Contrast Agents in MR Imaging 171
Himanshu Gupta and Ralph Weissleder
The use of target specific MR contrast agents can dramatically improve
information obtained by MR imaging. This review outlines the various
components of target specific MR contrast agents, including various carriers
(e.g., monoclonal antibodies, peptides, proteins, polysaccharides, polymers,
liposomes, and cells) as well as magnetic labels (e.g., metal ion chelates,
free radicals, and iron oxides) and focusses on some promising clinical appli¬
cations.
Index 185
Subscription Information Inside back cover
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| indexdate | 2024-07-09T18:08:21Z |
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| language | English |
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| physical | IX, 189 S. Ill., graph. Darst. |
| publishDate | 1996 |
| publishDateSearch | 1996 |
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| publisher | Saunders |
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| series | Magnetic resonance imaging clinics of North America |
| series2 | Magnetic resonance imaging clinics of North America |
| spelling | Contrast agents for body MR imaging Neil M. Rofsky, guest ed. Philadelphia [u.a.] Saunders 1996 IX, 189 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Magnetic resonance imaging clinics of North America 4,1 Produit de contraste Technique d'imagerie par résonance magnétique nucléaire Contrast Agents Magnetic Resonance Imaging Kontrastmittel (DE-588)4125566-5 gnd rswk-swf Kernspintomografie (DE-588)4120806-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Kernspintomografie (DE-588)4120806-7 s Kontrastmittel (DE-588)4125566-5 s DE-604 Rofsky, Neil M. Sonstige oth Magnetic resonance imaging clinics of North America 4,1 (DE-604)BV009716794 4,1 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007630885&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Contrast agents for body MR imaging Magnetic resonance imaging clinics of North America Produit de contraste Technique d'imagerie par résonance magnétique nucléaire Contrast Agents Magnetic Resonance Imaging Kontrastmittel (DE-588)4125566-5 gnd Kernspintomografie (DE-588)4120806-7 gnd |
| subject_GND | (DE-588)4125566-5 (DE-588)4120806-7 (DE-588)4143413-4 |
| title | Contrast agents for body MR imaging |
| title_auth | Contrast agents for body MR imaging |
| title_exact_search | Contrast agents for body MR imaging |
| title_full | Contrast agents for body MR imaging Neil M. Rofsky, guest ed. |
| title_fullStr | Contrast agents for body MR imaging Neil M. Rofsky, guest ed. |
| title_full_unstemmed | Contrast agents for body MR imaging Neil M. Rofsky, guest ed. |
| title_short | Contrast agents for body MR imaging |
| title_sort | contrast agents for body mr imaging |
| topic | Produit de contraste Technique d'imagerie par résonance magnétique nucléaire Contrast Agents Magnetic Resonance Imaging Kontrastmittel (DE-588)4125566-5 gnd Kernspintomografie (DE-588)4120806-7 gnd |
| topic_facet | Produit de contraste Technique d'imagerie par résonance magnétique nucléaire Contrast Agents Magnetic Resonance Imaging Kontrastmittel Kernspintomografie Aufsatzsammlung |
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