Precancerous conditions and endoscopic screening:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1997
|
| Schriftenreihe: | Gastrointestinal endoscopy clinics of North America
7,1 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VIII, 189 S. Ill., graph. Darst. |
Internformat
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| 245 | 1 | 0 | |a Precancerous conditions and endoscopic screening |c Guido N. J. Tytgat, guest ed. |
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| 300 | |a VIII, 189 S. |b Ill., graph. Darst. | ||
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| 650 | 2 | |a Tumeurs gastro-intestinales | |
| 650 | 2 | |a État précancéreux | |
| 650 | 4 | |a Endoscopy, Gastrointestinal | |
| 650 | 4 | |a Gastrointestinal Neoplasms | |
| 650 | 4 | |a Precancerous Conditions | |
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Datensatz im Suchindex
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PRECANCEROUS CONDITIONS AND ENDOSCOPIC SCREENING
CONTENTS
Preface xi
Guido N. J. Tytgat
Esophageal Columnar Metaplasia (Barrett's Esophagus) 1
Stuart Jon Spechler
This article explores the historical roots for the present confu¬
sion regarding diagnostic criteria for Barrett's esophagus. The
author recommends using an alternative classification system for
the columnar lined esophagus that does not rely solely on arbitrary
and imprecise endoscopic landmarks and measurements. Endo
scopic features that suggest the presence of intestinal metaplasia
in the esophagus are discussed and illustrated. The role of endoso
nography and the endoscopic techniques for ablating the esopha¬
geal columnar lining also are considered. Finally, the author lists
specific management recommendations for patients who have
esophageal columnar metaplasia.
Precursor Lesions for Cancer of the Cardia 19
Wilfred M. Weinstein
This article gives the rationale for the likelihood that the precursor
lesion for cancer of the cardia is either short segments of Barrett's
esophagus or even intestinali/ed (globlet cell change) mucosa at
a normally located squamo columnar junction. Intestinal metapla¬
sia of the cardia is likely a wear and tear phenomenon in manv
individuals without gastroesophageal reflux disease ((.1RD).
Markers that stratify risk further are required before routine biopsy
specimens of the Z line can be obtained in the clinical evaluation
of patients with GF.RD.
GASTROINTESTINAL ENDOSCOPY
CLINICS OF NORTH AMERICA VOLUME 7 • NL'MBKR 1 • JANUARY 1W V
Gastric Polyps as Precancerous Lesions 29
Jorg M. Schmitz and Manfred Stolte
Gastric polyps cover a wide range of possible diagnoses. Endoscop
ically, the nature of the lesions can be diagnosed with a high level
of probability. Nevertheless, histopathological diagnosis remains
mandatory. The macroscopic appearance of gastric polyps is de¬
scribed together with underlying histopathological diagnoses,
which are determinative for subsequent treatment.
Significance of Helicobacter Pylori Infection and Gastric Cancer:
Implications for Screening 47
Paul Moayyedi and Michael F. Dixon
Helicobacter pylori infection is a major cause of premature mortality.
Methods for diagnosing and treating this infection are now simple
and reliable. A screening program to eradicate H. pylori is relatively
straightforward to implement and is financially viable. This strat¬
egy initially involves a large capital outlay, however, and cannot
be recommended until it is proven that H. pylori eradication reduces
gastric cancer risk. It is also important to assess the magnitude of
benefit of a screening program against the harm that might be
engendered in terms of anxiety and adverse events from antibiotic
treatment. If screening is beneficial, then in developed countries it
could make death from H. pylori infection in the next century as
uncommon as mortality from tuberculosis has been in this century.
Screening of Patients with a Positive Family History of
Colorectal Cancer 65
Randall W. Burt
A positive family history is one of the most common risk factors
for colon cancer. The risk varies from moderately increased when
a first degree relative has colon cancer to high when a first degree
relative is diagnosed at an age less than 50 years or there are two
first degree relatives with large bowel malignancy. The risk of
colon cancer is extreme in the rare colon cancer syndromes of
familial adenomatous polyposis and hereditary nonpolyposis co¬
lon cancer. The extensive characterization of familial occurrence
of colon cancer has led to specific screening strategies for each of
these levels of familial risk.
Screening Modalities in Familial Adenomatous Polyposis and
Hereditary Nonpolyposis Colorectal Cancer 81
Allan D. Spigelman
The syndromes known as familial ademmiatous poh/posis (FAP) and
hereditary nonpolyposis colorectal cancer (HNPCC) represent para¬
digms of the arguments for and against screening surveillance.
This article details the protean manifestations of these conditions.
It is not a how to do it article with a suitably selected tranche of
VI CONTENTS
endoscopic pictures, but rather, it is an attempt to see what should
be done.
The Problem of "Flat" Colonic Adenoma 87
Shinei Kudo, Hiroshi Kashida, Satoru Tamura, and Takashi Nakajima
In this article, differences between depressed type early cancers
and the so called flat adenomas are clarified.
Role of Upper Gastrointestinal Surveillance in Patients with
Familial Adenomatous Polyposis 99
Toshio Sawada and Tetsuichiro Muto
Familial adenomatous polyposis (FAP) is an inherited autosomal
dominant disease in which hundreds and thousands of adenomas
with malignant potential are found throughout the colon and rec¬
tum. An increased risk for benign and malignant upper gastrointes¬
tinal neoplasia has long been recognized in patients with FAP. In
this article, the authors report their findings from a study of 35
registered patients to assess the prevalence, anatomic distribution,
depth of invasion, and natural history of upper gastrointestinal
tumors in patients with FAP.
Surveillance of Familial Adenomatous Polyposis Patients After
Ileorectal Anastomosis or Ileoanal Pouch Anastomosis 111
Guido N. J. Tytgat
This article summarizes the state of affairs with respect to rectal or
ileal polyps after colectomy in patients with familial adenomatous
polyposis and provides some practical hints with respect to tech¬
nique, follow up, pitfalls, and complications of endoscopic surveil¬
lance.
Screening and Surveillance of Ulcerative Colitis 129
Anthony T. R. Axon
There is an increased risk of colorectal cancer in patients who have
had an attack of chronic ulcerative colitis, and there is evidence to
suggest that patients with Crohn's disease are also at risk. It is
difficult to give a precise estimate of the increased danger that
patients with inflammatory bowel disease have oxer the normal
population because published results are inconsistent. Twenty
years ago patients with long standing extensive ulcerative colitis
were often advised to undergo proctocolectomv to protect against
the development of cancer, but since then most physicians have
adopted a policy of regular colonoscopic surveillance in an attempt
to detect early cancer or pie cancer. When published studies of
surveillance results are critically analyzed, it appears that relatively
little benefit accrues from this approach. Better methods of surveil¬
lance are needed to determine which individuals with chronic
ulcerative colitis are most likely to develop cancer.
contents vii
Contributions of the Molecular Biologist in Gastrointestinal
Cancer and Precancer Screening: Current Possibilities and
Future Prospects 147
Mikael E. Craanen, G. Johan A. Offerhaus, and Guido N. J. Tytgat
Molecular biology has become an integral part of research aimed
at improving diagnosis, therapy, and ultimately prevention of ma¬
lignant disease. This article focuses on the current possibilities and
limitations of molecular biology to improve existing screening and
surveillance protocols in specific gastrointestinal disease entities
frequently encountered in routine clinical practice.
Economic Aspects of Endoscopic Screening for Intestinal
Precancerous Conditions 165
Amnon Sonnenberg and Hashem B. El Serag
The relationship of costs to effectiveness in endoscopic screening
depends on the incidence rate of cancers arising from precancerous
lesions, the sensitivity and specificity rates of endoscopic screening,
and the effectiveness of timely diagnosis and surgery in preventing
death. Because all these parameters, which enter a medical decision
analysis, have a relatively large margin of error, it is not possible
to resolve the issue whether a screening should be performed
based on economic analyses alone. A crude "back of the envelope"
comparison of different screening programs suggests that colonos
copy in ulcerative colitis would result in the highest yield and
gastroscopy of the gastric stump in the lowest yield.
Index 185
Subscription Information Inside back cover
Viii CONTENTS |
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| series2 | Gastrointestinal endoscopy clinics of North America |
| spelling | Precancerous conditions and endoscopic screening Guido N. J. Tytgat, guest ed. Philadelphia [u.a.] Saunders 1997 VIII, 189 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Gastrointestinal endoscopy clinics of North America 7,1 Endoscopie Tumeurs gastro-intestinales État précancéreux Endoscopy, Gastrointestinal Gastrointestinal Neoplasms Precancerous Conditions Präkanzerose (DE-588)4175530-3 gnd rswk-swf Verdauungskanal (DE-588)4078786-2 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Verdauungskanal (DE-588)4078786-2 s Krankheit (DE-588)4032844-2 s Präkanzerose (DE-588)4175530-3 s DE-604 Tytgat, Guido N. J. Sonstige (DE-588)136452884 oth Gastrointestinal endoscopy clinics of North America 7,1 (DE-604)BV005455484 7,1 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007532923&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Precancerous conditions and endoscopic screening Gastrointestinal endoscopy clinics of North America Endoscopie Tumeurs gastro-intestinales État précancéreux Endoscopy, Gastrointestinal Gastrointestinal Neoplasms Precancerous Conditions Präkanzerose (DE-588)4175530-3 gnd Verdauungskanal (DE-588)4078786-2 gnd Krankheit (DE-588)4032844-2 gnd |
| subject_GND | (DE-588)4175530-3 (DE-588)4078786-2 (DE-588)4032844-2 (DE-588)4143413-4 |
| title | Precancerous conditions and endoscopic screening |
| title_auth | Precancerous conditions and endoscopic screening |
| title_exact_search | Precancerous conditions and endoscopic screening |
| title_full | Precancerous conditions and endoscopic screening Guido N. J. Tytgat, guest ed. |
| title_fullStr | Precancerous conditions and endoscopic screening Guido N. J. Tytgat, guest ed. |
| title_full_unstemmed | Precancerous conditions and endoscopic screening Guido N. J. Tytgat, guest ed. |
| title_short | Precancerous conditions and endoscopic screening |
| title_sort | precancerous conditions and endoscopic screening |
| topic | Endoscopie Tumeurs gastro-intestinales État précancéreux Endoscopy, Gastrointestinal Gastrointestinal Neoplasms Precancerous Conditions Präkanzerose (DE-588)4175530-3 gnd Verdauungskanal (DE-588)4078786-2 gnd Krankheit (DE-588)4032844-2 gnd |
| topic_facet | Endoscopie Tumeurs gastro-intestinales État précancéreux Endoscopy, Gastrointestinal Gastrointestinal Neoplasms Precancerous Conditions Präkanzerose Verdauungskanal Krankheit Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007532923&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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