Selected hematologic issues:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1997
|
| Schriftenreihe: | Infertility and reproductive medicine clinics of North America
8,1 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 157 S. Ill., graph. Darst. |
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| 650 | 4 | |a Generative organs, Female |x Hemorrhage | |
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Datensatz im Suchindex
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| adam_text |
I SELECTED HEMATOLOGIC ISSUES
CONTENTS
Foreword ix
Michael P. Diamond and Alan H. DeCherney
Preface xi
Eberhard F. Mammen
Platelet Activating Factor in Reproduction 1
Kouei Muguruma, Hisashi Narahara, Yasushi Kawano, and
John M. Johnston
This article reviews the role of platelet activating factor in repro¬
ductive biology, emphasizing its involvement in several processes
and the complications thereof. The authors believe that other
mediators and cytokines also are involved. Some investigators
have suggested a central role for one mediator that serves as the
trigger in each of these events. The authors believe that these
systems are regulated most probably by several affecters, among
which platelet activating factor is important.
Hemostasis During Ovulation Induction 25
Valerie C. Montgomery Rice and Richard E. Leach
Controlled ovarian hyperstimulation using injectable gonadotro
pins offers the benefit of recruiting multiple follicles for the pur¬
pose of in vitro fertilization or superovulation with intrauterine
inseminations. This article discusses the recent concepts regarding
the association of elevated estradiol levels in controlled ovarian
hyperstimulation and the potential risk for thrombosis as it affects
the fibrinolytic and coagulation systems.
INFERTILITY AND REPRODUCTIVE MEDICINE
CLINICS OF NORTH AMERICA
VOLUME 8 • NUMBER 1 • JANUARY 1997 V
Hemostasis During Hormone Replacement Therapy 35
Eberhard F. Mammen
Exogenous estrogen and progesterone supplementation in the
form of hormone replacement therapy in postmenopausal women
seems to protect against risks for cardiovascular disease. Hor¬
mone replacement therapy alters lipid profiles in a favorable way
and activates the fibrinolytic system without adversely affecting
the clotting system. There is no evidence that hormone replace¬
ment therapy increases the risk for arterial or venous thromboem
bolic events.
Antiphospholipid Antibodies: Immunology and Clinical
Consequences in Pregnancy 49
Charles J. Lockwood
Procoagulant antiphospholipid antibodies (APA) react to proteins
complexed with phospholipids. In the case of lupus anticoagu¬
lant, the protein is either prothrombin complexed with hexagonal
phase phospholipids or B2GPI complexed with anionic bilayer
phospholipids. The latter antibodies also account for anticardio
lipin antibody reactivity. Additional phospholipid binding pro¬
teins that may be targets for APA include annexin V, protein C,
protein S, and yet to be characterized endothelial and trophoblast
antigens. Although APA may be caused by conditions likely to
be associated with poor pregnancy outcomes, such as systemic
lupus erythematosus, these antibodies directly interfere with tro¬
phoblast function and seem to promote placental thrombosis and
vasculopathy. Thrombosis seems to result from APA interference
with various phospholipid associated anticoagulant proteins (e.g.,
B2GPI, antithrombin III, thrombomodulin, protein C, and protein
S). Because of the common side effects of the various treatments,
meticulous diagnostic criteria are required to diagnose lupus
anticoagulant activity and anticardiolipin antibody reactivity.
Immunotherapy for Unexplained Recurrent Spontaneous
Abortion 65
Salim Daya
Repeated spontaneous abortion is believed to be a manifestation
of failure in protective mechanisms which can be induced by
alloimmunication either passively using pooled intravenous im
munoglobulin or actively by paternal leukocyte infusion. The
effectiveness of intravenous immunoglobulin in unexplained re¬
current spontaneous abortion seems to be enhanced by commenc¬
ing treatment before conception and maintaining it until the end
of the second trimester. Paternal leukocyte immunization is effec¬
tive in women who have unexplained primary recurrent abortion
and who have no antipaternal cytotoxic antibody and no autoim¬
mune abnormalities.
Vi CONTENTS
Diagnosis and Management of Obstetric Bleeding 79
David R. Bryant and Mitchell P. Dombrowski
The hematologic and cardiovascular changes of pregnancy sig¬
nificantly influence the physiologic response to bleeding. General
principles of care can be applied regardless of the cause of bleed¬
ing. Specific causes of obstetric bleeding can be grouped ac¬
cording to the relationship to delivery. Peripartum hemorrhage
is typically caused by abnormal placentation, trauma, or a failure
of the natural mechanisms of postpartum hemostasis.
Management of Intraoperative Bleeding 95
Gunter Deppe and Vinay K. Malviya
Intraoperative hemorrhage, which may result in anemia, hypovo
lemia, and even death, is one of the most stressful situations
faced by any surgeon. Extensive diagnostic and clinical expertise
is needed in the evaluation and treatment of a bleeding patient.
A precise diagnosis is essential because of the availability of
general and specific measures. This article discusses an approach
to the management of patients experiencing intraoperative bleed¬
ing.
Blood and Blood Product Transfusion, Indications, and
Proper Use 109
Jeffery Dzieczkowski
Since the increased fear of infectious complications of transfusion
therapy, the indications for using blood components has been
scrutinized. Consensus recommendations from several panels and
committee are presented on the proper use of allogeneic and
autologous blood components. A periodic review of currently
accepted guidelines and criteria for the use of these products
behooves the clinician who may be faced with making such
decisions.
Diagnosis and Management of Anemia in Gynecologic
Patients 125
Joel L. Appel, Michele R. Lauria, and Kenneth L. Bergsman
Anemia is a common finding and often indicates significant un¬
derlying pathology. As obstetrician gynecologists become more
involved in the primary care of women, it is important for them
to have a basic understanding of the problem. This article pre¬
sents a brief overview of the general approach and evaluation of
anemia and highlights some common types seen in women.
Index 153
Subscription Information Inside back cover
CONTENTS Vii |
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| spelling | Selected hematologic issues Eberhard F. Mammen, guest ed. Philadelphia [u.a.] Saunders 1997 XIX, 157 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Infertility and reproductive medicine clinics of North America 8,1 Gynécologie Hémopathies Hémorragie Obstétrique Blood Diseases Generative organs, Female Hemorrhage Gynecology Obstetrics Frauenkrankheit (DE-588)4113621-4 gnd rswk-swf Schwangerschaft (DE-588)4053724-9 gnd rswk-swf Geburtshilfe (DE-588)4019604-5 gnd rswk-swf Sterilität (DE-588)4057338-2 gnd rswk-swf Hämostasestörung (DE-588)4022824-1 gnd rswk-swf Blutkrankheit (DE-588)4007281-2 gnd rswk-swf Blutgerinnung (DE-588)4007275-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Hämostasestörung (DE-588)4022824-1 s Geburtshilfe (DE-588)4019604-5 s DE-604 Frauenkrankheit (DE-588)4113621-4 s Schwangerschaft (DE-588)4053724-9 s Blutgerinnung (DE-588)4007275-7 s Sterilität (DE-588)4057338-2 s Blutkrankheit (DE-588)4007281-2 s Mammen, Eberhard F. Sonstige oth Infertility and reproductive medicine clinics of North America 8,1 (DE-604)BV004316184 8,1 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007508175&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Selected hematologic issues Infertility and reproductive medicine clinics of North America Gynécologie Hémopathies Hémorragie Obstétrique Blood Diseases Generative organs, Female Hemorrhage Gynecology Obstetrics Frauenkrankheit (DE-588)4113621-4 gnd Schwangerschaft (DE-588)4053724-9 gnd Geburtshilfe (DE-588)4019604-5 gnd Sterilität (DE-588)4057338-2 gnd Hämostasestörung (DE-588)4022824-1 gnd Blutkrankheit (DE-588)4007281-2 gnd Blutgerinnung (DE-588)4007275-7 gnd |
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| title | Selected hematologic issues |
| title_auth | Selected hematologic issues |
| title_exact_search | Selected hematologic issues |
| title_full | Selected hematologic issues Eberhard F. Mammen, guest ed. |
| title_fullStr | Selected hematologic issues Eberhard F. Mammen, guest ed. |
| title_full_unstemmed | Selected hematologic issues Eberhard F. Mammen, guest ed. |
| title_short | Selected hematologic issues |
| title_sort | selected hematologic issues |
| topic | Gynécologie Hémopathies Hémorragie Obstétrique Blood Diseases Generative organs, Female Hemorrhage Gynecology Obstetrics Frauenkrankheit (DE-588)4113621-4 gnd Schwangerschaft (DE-588)4053724-9 gnd Geburtshilfe (DE-588)4019604-5 gnd Sterilität (DE-588)4057338-2 gnd Hämostasestörung (DE-588)4022824-1 gnd Blutkrankheit (DE-588)4007281-2 gnd Blutgerinnung (DE-588)4007275-7 gnd |
| topic_facet | Gynécologie Hémopathies Hémorragie Obstétrique Blood Diseases Generative organs, Female Hemorrhage Gynecology Obstetrics Frauenkrankheit Schwangerschaft Geburtshilfe Sterilität Hämostasestörung Blutkrankheit Blutgerinnung Aufsatzsammlung |
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