Essentials of environmental toxicology: the effects of environmentally hazardous substances on human health
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Washington, DC [u.a.]
Taylor & Francis
1996
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 176 S. Ill., graph. Darst. |
| ISBN: | 1560324708 1560324694 |
Internformat
MARC
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| 245 | 1 | 0 | |a Essentials of environmental toxicology |b the effects of environmentally hazardous substances on human health |c W. William Hughes |
| 264 | 1 | |a Washington, DC [u.a.] |b Taylor & Francis |c 1996 | |
| 300 | |a XII, 176 S. |b Ill., graph. Darst. | ||
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| 650 | 7 | |a Toxicologie |2 gtt | |
| 650 | 4 | |a Environmental Exposure | |
| 650 | 4 | |a Environmental toxicology | |
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Datensatz im Suchindex
| _version_ | 1804125654889791488 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
1
3
PREFACE XI
INTRODUCTION TO ENVIRONMENTAL TOXICOLOGY 1
WHAT IS ENVIRONMENTAL TOXICOLOGY? 3
TERMINOLOGY 3
HISTORY OF TOXICOLOGY 4
SUBDISCIPLINES OF TOXICOLOGY 7
ECOLOGICAL CONCEPTS 10
RELEVANCE OF ENVIRONMENTAL TOXICOLOGY TO THE HUMAN SPECIES 12 STRUCTURAL
LEVELS OF ORGANIZATION 13
REVIEW QUESTIONS 16
TOXICOLOGICAL CONCEPTS 19
TOXICITY 20
TOXICOKINETICS AND TOXICODYNAMICS 21
CLASSIFICATION OF TOXICANTS 21
DETERMINATION OF TOXICITY 23
DETERMINING THE DOSES TO TEST 25
VARIABLES AFFECTING TOXICITY 25
REVIEW QUESTIONS 26
DOSE-RESPONSE RELATIONSHIPS 29
DOSE AND RESPONSE RELATIONSHIPS 30
DOSE-RESPONSE GRAPHS 30
STATISTICAL CONSIDERATIONS OF DOSE-RESPONSE 32
VII
IMAGE 2
VIII CONTENTS
INTERPRETING DOSE-RESPONSE DATA 36
REVIEW QUESTIONS 38
ABSORPTION OF TOXICANTS 43
INTERACTION OF TOXICANTS WITH CELLS 45
CELL MEMBRANE STRUCTURE 45
PROCESSES OF CELLULAR ABSORPTION 47
CELLULAR UPTAKE OF TOXICANTS 48
ROUTES OF ABSORPTION 49
REVIEW QUESTIONS 57
DISTRIBUTION AND STORAGE OF TOXICANTS 59
DISTRIBUTION OF TOXICANTS 60
FACTORS AFFECTING DISTRIBUTION OF TOXICANTS TO TISSUES 63
STORAGE OF TOXICANTS 65
REVIEW QUESTIONS 68
BIOTRANSFORMATION AND ELIMINATION OF TOXICANTS 71 BIOTRANSFORMATION OF
TOXICANTS 72
BIOTRANSFORMATION REACTIONS 73
LOCATION OF BIOTRANSFORMATION REACTIONS 73
FACTORS AFFECTING BIOTRANSFORMATION 75
PHASE I REACTIONS 76
PHASE II REACTIONS 76
ELIMINATION OF TOXICANTS 78
ADDITIONAL ROUTES OF ELIMINATION 81
REVIEW QUESTIONS 82
TARGET ORGAN TOXICITY 85
INTRODUCTION TO TARGET ORGAN TOXICITY 87
HEMATOTOXICITY 87
HEPATOTOXICITY 89
NEPHROTOXICITY 92
NEUROTOXICITY 94
DERMATOTOXICITY 96
IMAGE 3
T
8
10
CONTENTS IX
PULMONOTOXICITY 99
OTHER EXAMPLES OF TARGET ORGAN TOXICITY 102
REVIEW QUESTIONS 102
TERATOGENESIS, MUTAGENESIS, AND CARCINOGENESIS 105 INTRODUCTION TO
TERATOGENESIS, MUTAGENESIS, AND CARCINOGENESIS 107 REPLICATION 107
TRANSCRIPTION AND TRANSLATION 108
TERATOGENESIS 111
MUTAGENESIS 117
CARCINOGENESIS 120
REVIEW QUESTIONS 122
ENVIRONMENTAL TOXICANTS 125
INTRODUCTION TO ENVIRONMENTAL TOXICANTS 127
PESTICIDES 127
PLASTICS 133
METALS 133
ORGANIC SOLVENTS 137
OTHER ENVIRONMENTAL TOXICANTS 139
REVIEW QUESTIONS 140
RISK ASSESSMENT 143
INTRODUCTION TO RISK 144
RISK ASSESSMENT 144
RISK MANAGEMENT 146
SAFETY 146
CONCLUSIONS 147
REVIEW QUESTIONS 147
APPENDIX: RESOURCES IN ENVIRONMENTAL TOXICOLOGY 149 GLOSSARY 153
INDEX 165
|
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| illustrated | Illustrated |
| indexdate | 2024-07-09T18:05:00Z |
| institution | BVB |
| isbn | 1560324708 1560324694 |
| language | English |
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| physical | XII, 176 S. Ill., graph. Darst. |
| publishDate | 1996 |
| publishDateSearch | 1996 |
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| publisher | Taylor & Francis |
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| spelling | Hughes, W. William Verfasser aut Essentials of environmental toxicology the effects of environmentally hazardous substances on human health W. William Hughes Washington, DC [u.a.] Taylor & Francis 1996 XII, 176 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Gezondheidseffecten gtt Milieutoxicologie gtt Toxicologie gtt Environmental Exposure Environmental toxicology Hazardous Substances poisoning Umwelttoxikologie (DE-588)4121813-9 gnd rswk-swf Umwelttoxikologie (DE-588)4121813-9 s DE-604 SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007481942&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Hughes, W. William Essentials of environmental toxicology the effects of environmentally hazardous substances on human health Gezondheidseffecten gtt Milieutoxicologie gtt Toxicologie gtt Environmental Exposure Environmental toxicology Hazardous Substances poisoning Umwelttoxikologie (DE-588)4121813-9 gnd |
| subject_GND | (DE-588)4121813-9 |
| title | Essentials of environmental toxicology the effects of environmentally hazardous substances on human health |
| title_auth | Essentials of environmental toxicology the effects of environmentally hazardous substances on human health |
| title_exact_search | Essentials of environmental toxicology the effects of environmentally hazardous substances on human health |
| title_full | Essentials of environmental toxicology the effects of environmentally hazardous substances on human health W. William Hughes |
| title_fullStr | Essentials of environmental toxicology the effects of environmentally hazardous substances on human health W. William Hughes |
| title_full_unstemmed | Essentials of environmental toxicology the effects of environmentally hazardous substances on human health W. William Hughes |
| title_short | Essentials of environmental toxicology |
| title_sort | essentials of environmental toxicology the effects of environmentally hazardous substances on human health |
| title_sub | the effects of environmentally hazardous substances on human health |
| topic | Gezondheidseffecten gtt Milieutoxicologie gtt Toxicologie gtt Environmental Exposure Environmental toxicology Hazardous Substances poisoning Umwelttoxikologie (DE-588)4121813-9 gnd |
| topic_facet | Gezondheidseffecten Milieutoxicologie Toxicologie Environmental Exposure Environmental toxicology Hazardous Substances poisoning Umwelttoxikologie |
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