Drug receptor subtypes and ingestive behaviour:
Neural mechanisms of ingestive behaviour has long been one of the most intensively investigated areas within neuroscience. Drug studies have been introduced to develop anti-obesity compounds and, more recently, to identify neurotransmitters which might be involved in the control of ingestive behavio...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London [u.a.]
Acad. Press
1996
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | Neural mechanisms of ingestive behaviour has long been one of the most intensively investigated areas within neuroscience. Drug studies have been introduced to develop anti-obesity compounds and, more recently, to identify neurotransmitters which might be involved in the control of ingestive behaviour. The current focus within this field is towards neurotransmitter receptors as it has become known that there are multiple receptor subtypes for each identified neurotransmitter The study of drug receptor subtypes and ingestive behaviour is growing very rapidly, and has become quite complex. This unique volume is designed to guide students and investigators through a number of different neurotransmitter systems and provide them with the latest information on the identities of receptor subtypes most relevant in the study of ingestive behaviour. As such, it will prove enormously useful to all engaged in studies on appetite and obesity treatment |
| Beschreibung: | XVI, 399 S. Ill., graph. Darst. |
| ISBN: | 0121876209 |
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| 520 | 3 | |a Neural mechanisms of ingestive behaviour has long been one of the most intensively investigated areas within neuroscience. Drug studies have been introduced to develop anti-obesity compounds and, more recently, to identify neurotransmitters which might be involved in the control of ingestive behaviour. The current focus within this field is towards neurotransmitter receptors as it has become known that there are multiple receptor subtypes for each identified neurotransmitter | |
| 520 | |a The study of drug receptor subtypes and ingestive behaviour is growing very rapidly, and has become quite complex. This unique volume is designed to guide students and investigators through a number of different neurotransmitter systems and provide them with the latest information on the identities of receptor subtypes most relevant in the study of ingestive behaviour. As such, it will prove enormously useful to all engaged in studies on appetite and obesity treatment | ||
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| adam_text | 2 ? DRUG RECEPTOR SUBTYPES AND INGESTIVE BEHAVIOUR EDITED BY STEVEN J.
COOPER DEPARTMENT OF PSYCHOLOGY, UNIVERSITY OF DURHAM DURHAM, UK AND
PETER G.CLIFTON LABORATORY OF EXPERIMENTAL PSYCHOLOGY, SCHOOL OF BIOLOGY
UNIVERSITY OF SUSSEX, BRIGHTON, UK ACADEMIC PRESS HARCOURT BRACE &
COMPANY, PUBLISHERS LONDON SAN DIEGO NEW YORK BOSTON SYDNEY TOKYO
TORONTO CONTENTS CONTRIBUTORS XI PREFACE XV 1 RECEPTOR SUBTYPE AND
AFFINITY STATE UNDERLYING THE SATIETY ACTIONS OF CHOLECYSTOKININ (CCK) 1
TIMOTHY H. MORAN 1 INTRODUCTION 1 2 CCK RECEPTOR SUBTYPES 1 3 SATIETY
ACTIONS OF CCK 3 4 SUMMARY 13 ACKNOWLEDGEMENTS 15 REFERENCES 15 2
CHOLECYSTOKININ-DOPAMINE INTERACTIONS IN SATIETY 19 P. SODERSTEN, I.
BEDNAR, G. A. QURESHI, H. CARTER, M. QIAN, H. MAMOUN, J. M. KAPLAN AND
A. E. JOHNSON 1 INTRODUCTION 19 2 RESULTS 22 3 COMMENTS 32
ACKNOWLEDGEMENTS 34 REFERENCES 34 3 ROLE OF 5-HYDROXYTRYPTAMINE RECEPTOR
SUBTYPES IN SATIETY AND ANIMAL MODELSOFEATING DISORDERS 39 ROSARIO
SAMANIN AND GIULIANO GRIGNASCHI 1 INTRODUCTION 39 2 ROLE OF 5-HT
RECEPTORS IN THE MECHANISMS SPECIFICALLY CONTROLLING SATIETY . . 40 3
ROLE OF 5-HT 2A RECEPTORS IN ANOREXIA INDUCED BY RESTRAINT STRESS 44 4
ROLE OF 5-HT RECEPTOR SUBTYPES IN NEUROPEPTIDE Y-INDUCED HYPERPHAGIA . .
47 5 CONCLUSIONS 53 ACKNOWLEDGEMENTS 53 REFERENCES 54 4 5-HT RECEPTOR
SUBTYPES INFLUENCING FEEDING AND DRINKING: FOCUS ON THE PERIPHERY 59
KENNY J. SIMANSKY 1 INTRODUCTION 59 2 PERIPHERAL 5-HT AND FEEDING 60
CONTENTS 3 PERIPHERAL 5-HT AND DRINKING 80 4 CONCLUSION 88
ACKNOWLEDGEMENTS 89 REFERENCES 89 INSULIN AND SEROTONIN ACTIONS AND
INTERACTIONS AND THE CONTROL OF FEEDING AND METABOLISM 99 MARLINE OROSCO
AND STELIOS NICOLAIDIS 1 INTRODUCTION 99 2 RESPECTIVE ROLES OF SEROTONIN
AND INSULIN IN THE CONTROL OF FOOD INTAKE . . . 100 3 RESPECTIVE ROLES
OF SEROTONIN AND INSULIN IN METABOLISM 105 4 INSULIN-SEROTONIN
INTERACTIONS * . 107 5 MEANING OF THE 5-HT-INSULIN INTERACTION 113 6 HOW
CAN THE ARGUMENTS FOR AND AGAINST THE INVOLVEMENT OF INSULIN*5-HT
INTERACTION IN FEEDING BE RECONCILED? 118 7 CONCLUSIONS 119 REFERENCES
120 OPIOID RECEPTOR SUBTYPE ANTAGONISTS AND INGESTION 127 RICHARD J.
BODNAR 1 OPIOID LIGANDS, RECEPTOR SUBTYPES AND SELECTIVE ANTAGONISTS 127
2 SPONTANEOUS FEEDING AND BODY WEIGHT CONTROL 128 3 INTAKE FOLLOWING
FOOD DEPRIVATION 130 4 GLUCOPRIVIC FEEDING 131 5 PALATABLE AND
STRESS-INDUCED INTAKE 133 6 WATER INTAKE UNDER CHALLENGE SITUATIONS 136
7 SUMMARY 138 ACKNOWLEDGEMENTS 140 REFERENCES 140 STIMULATION OF
INGESTIVE BEHAVIOUR BY PREFERENTIAL AND SELECTIVE OPIOID AGONISTS 147
BLAKE A. GOSNELL AND ALLEN S. LEVINE , 1 INTRODUCTION 147 2 STUDIES WITH
SYSTEMICALLY ADMINISTERED OPIOIDS 148 3 STUDIES WITH
INTRACEREBROVENTRICULAR ADMINISTRATION OF OPIOIDS 150 4 STUDIES WITH
LOCALIZED INJECTIONS OF OPIOIDS 152 5 SUMMARY 159 ACKNOWLEDGEMENTS 160
REFERENCES 160 OPIOID RECEPTOR SUBTYPES AND STIMULATION-INDUCED FEEDING
. . . 167 KENNETH D. CARR 1 INTRODUCTION 167 2 STIMULATION-INDUCED
FEEDING AND SELF-STIMULATION 169 3 CHRONIC FOOD RESTRICTION AND
STREPTOZOTOCIN-INDUCED DIABETES 176 4 HYPOTHESIS: A COMMON OPIOID
MECHANISM MEDIATES SIF AND FACILITATES ICSS . 178 CONTENTS VII 5 BRAIN
REGIONAL OPIOID BINDING AND PEPTIDE LEVELS 181 6 SUMMARY AND CONCLUSIONS
186 ACKNOWLEDGEMENTS 187 REFERENCES 187 9 SENSITIZATION TO THE INGESTIVE
EFFECTS OF OPIOIDS 193 PAOLO NENCINI 1 INTRODUCTION 193 2 FEEDING
BEHAVIOUR AND THE MOTIVE CIRCUIT 195 3 SENSITIZATION OF MOTIVATED
BEHAVIOUR 197 4 CHRONIC ADMINISTRATION OF OPIOIDS AND FEEDING BEHAVIOUR
199 5 SENSITIZATION TO THE PROPHAGIC EFFECTS OF K OPIOIDS 201 6
SENSITIZATION TO THE PROPHAGIC EFFECTS OF FT OPIOIDS 204 7 FOOD
RESTRICTION AND SENSITIZATION TO THE PROPHAGIC EFFECTS OF OPIOIDS . . .
. 209 8 SENSITIZATION TO THE PROPHAGIC EFFECTS OF OPIOIDS AS A MODEL OF
INGESTIVE DISORDERS 210 REFERENCES 212 10 DOPAMINE-OPIOID MECHANISMS IN
INGESTION 219 FRANCO J. VACCARINO 1 INTRODUCTION 219 2 PSYCHOMOTOR
STIMULANT AND OPIATE-INDUCED FEEDING 219 3 DOPAMINE-OPIATE INTERACTIONS
AND FEEDING: KEY INVOLVEMENT OF REWARD MECHANISMS 221 4 NUCLEUS
ACCUMBENS OPIATE AND DOPAMINERGIC ACTIONS MEDIATE DISTINCT FEEDING
EFFECTS 224 ACKNOWLEDGEMENTS 227 REFERENCES 227 11 DOPAMINE RECEPTOR
SUBTYPES AND INGESTIVE BEHAVIOUR 233 PHILIP TERRY 1 INTRODUCTION 233 2
EFFECTS OF NON-SELECTIVE DRUGS 235 3 DJ-TYPE RECEPTOR AGONISTS AND
ANTAGONISTS 238 4 D 2 -TYPE RECEPTOR AGONISTS AND ANTAGONISTS 246 5
INTERACTIONS BETWEEN D R AND D 2 -TYPE RECEPTORS 255 6 INTERACTIONS OF
SUBTYPE-SELECTIVE DRUGS WITH OTHER SYSTEMS 257 7 CONCLUSIONS 257
ACKNOWLEDGEMENTS 258 REFERENCES 258 12 IMIDAZOLINE RECEPTORS AND
INGESTION 267 HELEN C. JACKSON AND DAVID J. NUTT 1 INTRODUCTION . 267 2
IDAZOXAN AND FOOD INTAKE 268 3 I 2 RECEPTOR LIGANDS AND FOOD INTAKE 271
4 PHARMACOLOGICAL MECHANISMS UNDERLYING THE EFFECTS OF IDAZOXAN AND I 2
LIGANDS ON FOOD INTAKE 273 VIII CONTENTS 5 WATER INTAKE STUDIES 276 6
EFFECT OF IDAZOXAN AND RX 801077 ON LOCOMOTOR ACTIVITY 276 7 GENERAL
CONSIDERATIONS AND FUTURE DIRECTIONS 276 REFERENCES 280 13 MEDIAL
HYPOTHALAMIC A 2 -ADRENERGIC AND SEROTONERGIC EFFECTS ON INGESTIVE
BEHAVIOUR 285 PAULJ. CURRIE 1 INTRODUCTION 285 2 ADRENERGIC STIMULATION
OF FEEDING 286 3 SEROTONERGIC INHIBITION OF FEEDING 288 4 DIURNAL
RHYTHM OF PVN NORADRENALINE AND 5-HT 289 5 ANTAGONISTIC FUNCTION OF PVN
NORADRENALINE AND 5-HT 291 6 CONCLUSIONS 294 REFERENCES 294 14 GLUTAMATE
AND ITS RECEPTORS IN LATERAL HYPOTHALAMIC STIMULATION OFEATING 301 B.
GLENN STANLEY 1 GOALS AND HYPOTHESIS 301 2 THE LATERAL HYPOTHALAMUS AND
FEEDING BEHAVIOUR 301 3 GLUTAMATE AS AN EXCITATORY NEUROTRANSMITTER:
GENERAL BACKGROUND . . . . 303 4 GLUTAMATE AND FEEDING AT SITES OTHER
THAN THE LH 305 5 LH GLUTAMATE AND FEEDING STIMULATION: INITIAL RESULTS
305 6 GLUTAMATE RECEPTOR SUBTYPES AND EATING STIMULATION 307 7 MEAL
PATTERNS AND BEHAVIOURAL SPECIFICITY 309 8 SITE OF ACTION 311 9
IMPLICATIONS FOR LH NEURONAL INVOLVEMENT IN FEEDING STIMULATION . . . .
315 10 ANTAGONIST DATA SUGGESTING INVOLVEMENT OF NMDA RECEPTORS 316 11
ENDOGENOUS LH GLUTAMATE, NMDA RECEPTORS AND NATURAL EATING . . . . 317
12 ENDOGENOUS LH GLUTAMATE, NMDA RECEPTORS AND BODY WEIGHT 317 13
CONCLUSIONS AND PERSPECTIVES 318 ACKNOWLEDGEMENT 319 REFERENCES 319 15
THE RECEPTOR BASIS OF NEUROPEPTIDE Y-INDUCED FOOD INTAKE . . . 323 ERIC
S. CORP 1 OVERVIEW OF NEUROPEPTIDE Y RECEPTOR PHARMACOLOGY 323 2
NPY-INDUCED FEEDING: FOREBRAIN SITES OF ACTION 327 3 NPY AND FEEDING:
HINDBRAIN SITES OF ACTION 333 4 NPY RECEPTOR COUPLING AND SIGNAL
TRANSDUCTION 338 5 SUMMARY 341 ACKNOWLEDGEMENTS 341 REFERENCES 341 16
BENZODIAZEPINE RECEPTORS AND THE DETERMINATION OF PALATABILITY . 347
STEVEN J. COOPER AND SUZANNE HIGGS 1 INTRODUCTION 347 2 BEHAVIOURAL
PROCESSES IN BENZODIAZEPINE-INDUCED HYPERPHAGIA 348 CONTENTS IX 3
PHARMACOLOGY OF BENZODIAZEPINE RECEPTOR-MEDIATED CHANGES IN FOOD INTAKE
. 354 4 NEURAL SUBSTRATES 356 5 RECEPTOR SUBTYPES 360 ACKNOWLEDGEMENTS
363 REFERENCES 363 17 NEUROCHEMICAL INTERACTIONS IN THE CONTROL OF
INGESTIVE BEHAVIOUR . 369 ELIZABETH M. SOMERVILLE AND PETER G. CLIFTON 1
INTRODUCTION 369 2 FEEDING: THE BEHAVIOURAL CONTEXT 369 3 A NEURAL MODEL
FOR FEEDING 372 4 NEUROCHEMICAL MODULATION OF FEEDING BEHAVIOUR 378 5
CONCLUSION 384 REFERENCES 385 INDEX 389 A COLOUR PLATE SECTION APPEARS
BETWEEN PAGES 336 AND 337
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| spelling | Drug receptor subtypes and ingestive behaviour ed. by Steven J. Cooper ... London [u.a.] Acad. Press 1996 XVI, 399 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neural mechanisms of ingestive behaviour has long been one of the most intensively investigated areas within neuroscience. Drug studies have been introduced to develop anti-obesity compounds and, more recently, to identify neurotransmitters which might be involved in the control of ingestive behaviour. The current focus within this field is towards neurotransmitter receptors as it has become known that there are multiple receptor subtypes for each identified neurotransmitter The study of drug receptor subtypes and ingestive behaviour is growing very rapidly, and has become quite complex. This unique volume is designed to guide students and investigators through a number of different neurotransmitter systems and provide them with the latest information on the identities of receptor subtypes most relevant in the study of ingestive behaviour. As such, it will prove enormously useful to all engaged in studies on appetite and obesity treatment Absorptie gtt Geneesmiddelen gtt Geneesmiddelentransport gtt Psicofarmacologia larpcal Receptoren gtt Verzadiging gtt Voedselopname gtt Appetite drug effects Digestion Digestive organs Drug receptors Receptors, Drug Receptors, Neurotransmitter Neurotransmitter-Rezeptor (DE-588)4171601-2 gnd rswk-swf Pharmakologie (DE-588)4045687-0 gnd rswk-swf Ernährungsgewohnheit (DE-588)4136846-0 gnd rswk-swf Neurotransmitter-Rezeptor (DE-588)4171601-2 s Ernährungsgewohnheit (DE-588)4136846-0 s Pharmakologie (DE-588)4045687-0 s DE-604 Cooper, Steven J. Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007437766&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Drug receptor subtypes and ingestive behaviour Absorptie gtt Geneesmiddelen gtt Geneesmiddelentransport gtt Psicofarmacologia larpcal Receptoren gtt Verzadiging gtt Voedselopname gtt Appetite drug effects Digestion Digestive organs Drug receptors Receptors, Drug Receptors, Neurotransmitter Neurotransmitter-Rezeptor (DE-588)4171601-2 gnd Pharmakologie (DE-588)4045687-0 gnd Ernährungsgewohnheit (DE-588)4136846-0 gnd |
| subject_GND | (DE-588)4171601-2 (DE-588)4045687-0 (DE-588)4136846-0 |
| title | Drug receptor subtypes and ingestive behaviour |
| title_auth | Drug receptor subtypes and ingestive behaviour |
| title_exact_search | Drug receptor subtypes and ingestive behaviour |
| title_full | Drug receptor subtypes and ingestive behaviour ed. by Steven J. Cooper ... |
| title_fullStr | Drug receptor subtypes and ingestive behaviour ed. by Steven J. Cooper ... |
| title_full_unstemmed | Drug receptor subtypes and ingestive behaviour ed. by Steven J. Cooper ... |
| title_short | Drug receptor subtypes and ingestive behaviour |
| title_sort | drug receptor subtypes and ingestive behaviour |
| topic | Absorptie gtt Geneesmiddelen gtt Geneesmiddelentransport gtt Psicofarmacologia larpcal Receptoren gtt Verzadiging gtt Voedselopname gtt Appetite drug effects Digestion Digestive organs Drug receptors Receptors, Drug Receptors, Neurotransmitter Neurotransmitter-Rezeptor (DE-588)4171601-2 gnd Pharmakologie (DE-588)4045687-0 gnd Ernährungsgewohnheit (DE-588)4136846-0 gnd |
| topic_facet | Absorptie Geneesmiddelen Geneesmiddelentransport Psicofarmacologia Receptoren Verzadiging Voedselopname Appetite drug effects Digestion Digestive organs Drug receptors Receptors, Drug Receptors, Neurotransmitter Neurotransmitter-Rezeptor Pharmakologie Ernährungsgewohnheit |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007437766&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT cooperstevenj drugreceptorsubtypesandingestivebehaviour |