Collectins and innate immunity:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Springer [u.a.]
1996
|
| Schriftenreihe: | Molecular biology intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 189 S. Ill., graph. Darst. |
| ISBN: | 3540615407 1570593779 0412125811 |
Internformat
MARC
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-007388154 | ||
Datensatz im Suchindex
| _version_ | 1804125523739148288 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
1. COLLECTINS 1
KEDARNATH N. SASTRY AND R. ALAN B. EZEKOWITZ
2. SURFACTANT PROTEIN A 9
FRANCIS X. MCCORMACK AND JEFFREY A. WHITSETT INTRODUCTION 9
GENE STRUCTURE AND EXPRESSION 11
PROTEIN 15
LIGANDS AND STRUCTURE/FUNCTION RELATIONSHIPS 18
SURFACTANT FUNCTIONS 23
HOST DEFENSE FUNCTIONS 28
SURFACTANT PROTEIN A AND DISEASE 37
FUTURE DIRECTIONS 40
3. TWO BOVINE COLLECTINS: CONGLUTININ AND CL-43 51
UFFE HOLMSKOV AND JENS CHR. JENSENIUS INTRODUCTION 51
PRIMARY STRUCTURE OF CONGLUTININ AND CL-43 52
OVERALL STRUCTURE 56
GENOMIC ORGANIZATION 57
EVOLUTION 58
CARBOHYDRATE SELECTIVITY OF CONGLUTININ AND CL-43 59 INTERACTION OF
CONGLUTININ WITH COMPLEMENT COMPONENT C3 61 BIOLOGICAL FUNCTION 64
CONCLUSION 66
4. FUNCTIONAL ASPECTS OF MANNOSE-BINDING PROTEIN 73
M. W. TURNER INTRODUCTION 73
THE ONTOGENY OF MBP 74
MBP AS AN ACUTE PHASE PROTEIN 75
THE HALF-LIFE AND TISSUE DISTRIBUTION OF MBP 75
THE INTERACTION OF MBP WITH MICROORGANISMS 76
ACTIVATION OF COMPLEMENT BY MANNOSE-BINDING PROTEIN 80 MBP DEFICIENCY
AND ITS CLINICAL SIGNIFICANCE 82
MBP AND AUTOIMMUNE DISEASE 90
SUMMARY 91
IMAGE 2
5. CLQ: STRUCTURAL AND FUNCTIONAL SIMILARITIES TO THE COUECTINS .... 99
KENNETH B.M. REID INTRODUCTION 99
STRUCTURE OF CLQ 100
FUNCTION OF CLQ 105
GENOMIC ORGANIZATION OF THE GENES ENCODING THE CHAINS OF HUMAN CLQ 107
CONCLUSIONS 108
6. SURFACTANT PROTEIN D 113
EDMOND CROUCH AND KEVAN HARTSHORN INTRODUCTION 113
HISTORICAL PERSPECTIVES 113
MOLECULAR STRUCTURE 114
PRODUCTION OF SP-D 116
ONTOGENY 119
EVOLUTION 120
FUNCTIONAL PROPERTIES 120
SUMMARY OF STRUCTURE-FUNCTION RELATIONSHIPS 129
FUTURE DIRECTIONS AND ANTICIPATED ADVANCEMENTS 131
7. GENETICS OF HUMAN MANNAN-BINDING PROTEIN 139
PETER GARRED, HANS O. MADSEN AND ARNE SVEJGAARD INTRODUCTION 139
THE MOLECULAR STRUCTURE AND GENE REGULATION OF MBP 140 THE STRUCTURAL
ALLELES OF THE MBP GENE 141
PROMOTER ALLELES OF THE MBP GENE 150
THE CLINICAL RELVANCE OF MBP ALLELES 152
A DOUBLE-EDGED SWORD IN IMMUNE DEFENSE? MAINTENANCE OF POLYMORPHISMS 156
DETECTION OF MBP ALLELES 159
CONCLUDING REMARKS 161
8. MASP (MBP-ASSOCIATED SERINE PROTEASE) 165
MISAO MATSUSHITA AND TEIZO FUJITA INTRODUCTION 165
ISOLATION OF MBP-ASSOCIATED SERINE PROTEASE 166
STRUCTURE OF MASP 167
MASP FUNCTION 170
MASP IN NONHUMAN SPECIES 172
COMPLEMENT ACTIVATION ON MAMMALIAN CELLS BY MBP-MASP 174 THE LECTIN
PATHWAY 175
CONCLUSION 177
INDEX 183
|
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| dewey-full | 616.07/9 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.07/9 |
| dewey-search | 616.07/9 |
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| id | DE-604.BV011033228 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:02:55Z |
| institution | BVB |
| isbn | 3540615407 1570593779 0412125811 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007388154 |
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| physical | 189 S. Ill., graph. Darst. |
| publishDate | 1996 |
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| series2 | Molecular biology intelligence unit |
| spelling | Collectins and innate immunity R. Alan B. Ezekowitz ... New York [u.a.] Springer [u.a.] 1996 189 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Eiwitten gtt Carrier Proteins immunology Carrier Proteins physiology Collagen immunology Collagen physiology Collectins Immunity, Innate Lectins immunology Lectins physiology Protein Structure, Secondary Angeborene Immunität (DE-588)4739713-5 gnd rswk-swf Collectine (DE-588)4441652-0 gnd rswk-swf Immunität Medizin (DE-588)4120476-1 gnd rswk-swf Lectine (DE-588)4034971-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Lectine (DE-588)4034971-8 s Immunität Medizin (DE-588)4120476-1 s DE-604 Angeborene Immunität (DE-588)4739713-5 s Collectine (DE-588)4441652-0 s Ezekowitz, R. Alan B. Sonstige oth SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007388154&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Collectins and innate immunity Eiwitten gtt Carrier Proteins immunology Carrier Proteins physiology Collagen immunology Collagen physiology Collectins Immunity, Innate Lectins immunology Lectins physiology Protein Structure, Secondary Angeborene Immunität (DE-588)4739713-5 gnd Collectine (DE-588)4441652-0 gnd Immunität Medizin (DE-588)4120476-1 gnd Lectine (DE-588)4034971-8 gnd |
| subject_GND | (DE-588)4739713-5 (DE-588)4441652-0 (DE-588)4120476-1 (DE-588)4034971-8 (DE-588)4143413-4 |
| title | Collectins and innate immunity |
| title_auth | Collectins and innate immunity |
| title_exact_search | Collectins and innate immunity |
| title_full | Collectins and innate immunity R. Alan B. Ezekowitz ... |
| title_fullStr | Collectins and innate immunity R. Alan B. Ezekowitz ... |
| title_full_unstemmed | Collectins and innate immunity R. Alan B. Ezekowitz ... |
| title_short | Collectins and innate immunity |
| title_sort | collectins and innate immunity |
| topic | Eiwitten gtt Carrier Proteins immunology Carrier Proteins physiology Collagen immunology Collagen physiology Collectins Immunity, Innate Lectins immunology Lectins physiology Protein Structure, Secondary Angeborene Immunität (DE-588)4739713-5 gnd Collectine (DE-588)4441652-0 gnd Immunität Medizin (DE-588)4120476-1 gnd Lectine (DE-588)4034971-8 gnd |
| topic_facet | Eiwitten Carrier Proteins immunology Carrier Proteins physiology Collagen immunology Collagen physiology Collectins Immunity, Innate Lectins immunology Lectins physiology Protein Structure, Secondary Angeborene Immunität Collectine Immunität Medizin Lectine Aufsatzsammlung |
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