Molecular basis of NK cell recognition and function:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Karger
1996
|
| Schriftenreihe: | Chemical immunology
64 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 184 S. Ill., graph. Darst. |
| ISBN: | 3805563329 |
Internformat
MARC
| LEADER | 00000nam a2200000 cb4500 | ||
|---|---|---|---|
| 001 | BV011006210 | ||
| 003 | DE-604 | ||
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| 007 | t | ||
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| 016 | 7 | |a 949028835 |2 DE-101 | |
| 020 | |a 3805563329 |9 3-8055-6332-9 | ||
| 035 | |a (OCoLC)35110225 | ||
| 035 | |a (DE-599)BVBBV011006210 | ||
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| 084 | |a XD 3100 |0 (DE-625)152552:12905 |2 rvk | ||
| 245 | 1 | 0 | |a Molecular basis of NK cell recognition and function |c vol. ed. L. Moretta |
| 264 | 1 | |a Basel [u.a.] |b Karger |c 1996 | |
| 300 | |a XII, 184 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Chemical immunology |v 64 | |
| 650 | 4 | |a Killer Cells, Natural | |
| 650 | 4 | |a Killer cells | |
| 650 | 0 | 7 | |a HLA |0 (DE-588)4160063-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Natürliche Killerzelle |0 (DE-588)4171290-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a MHC Klasse I |0 (DE-588)4313494-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Molekularbiologie |0 (DE-588)4039983-7 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Natürliche Killerzelle |0 (DE-588)4171290-0 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Natürliche Killerzelle |0 (DE-588)4171290-0 |D s |
| 689 | 1 | 1 | |a Molekularbiologie |0 (DE-588)4039983-7 |D s |
| 689 | 1 | |5 DE-604 | |
| 689 | 2 | 0 | |a Natürliche Killerzelle |0 (DE-588)4171290-0 |D s |
| 689 | 2 | 1 | |a MHC Klasse I |0 (DE-588)4313494-4 |D s |
| 689 | 2 | |5 DE-604 | |
| 689 | 3 | 0 | |a Natürliche Killerzelle |0 (DE-588)4171290-0 |D s |
| 689 | 3 | 1 | |a HLA |0 (DE-588)4160063-0 |D s |
| 689 | 3 | |5 DE-604 | |
| 700 | 1 | |a Moretta, Lorenzo |e Sonstige |4 oth | |
| 830 | 0 | |a Chemical immunology |v 64 |w (DE-604)BV002307222 |9 64 | |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007368917&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-007368917 | |
Datensatz im Suchindex
| _version_ | 1807320433341497344 |
|---|---|
| adam_text |
CONTENTS
PREFACE
.
XI
MHC-CLASS
L-DEPENDENT
AND
-INDEPENDENT
NK
CELL
SPECIFICITY
W.M.
YOKOYAMA,
ST.
LOUIS,
MO.;
A.
REICHLIN,
D.H.
MARGULIES,
BETHESDA,
MD.;
H.R.C.
SMITH,
ST.
LOUIS,
MO
.
1
INTRODUCTION
.
1
MURINE
NK
CELL
RECEPTORS
SPECIFIC
FOR
TARGET
CELL
MHC
CLASS
I
MOLECULES:
THE
LY-49
FAMILY
OF
MOLECULES
.
2
EVIDENCE
THAT
LY-49A
IS
AN
NK
CELL
RECEPTOR
FOR
MHC
CLASS
I
.
3
INTERACTION
OF
LY-49A
WITH
PEPTIDE-BINDING
DOMAINS
OF
MHC
CLASS
I
.
.
.
4
THE
POLYMORPHIC
LY-49
FAMILY
OF
MOLECULES
.
6
LY-49-RELATED
MOLECULES
AS
NK
CELL
RECEPTORS
.
8
RELATIONSHIP
OF
LY-49
MOLECULES
TO
HUMAN
NK
CELL
RECEPTORS
.
10
MHC
CLASS
I-INDEPENDENT
NK
CELL
SPECIFICITY
.
11
ACKNOWLEDGEMENTS
.
14
REFERENCES
.
14
RECOGNITION
AND
SIGNALING
BY
MOUSE
LY-49
RECEPTORS
W.E.
SEAMAN,
B.
DANIELS,
J.
RYAN,
M.
NAKAMURA,
E.
NIEMI,
SAN
FRANCISCO,
CALIF.
.
19
INTRODUCTION
.
19
LY-49A
HAS
A
FUNCTIONAL
CARBOHYDRATE
RECOGNITION
DOMAIN
(CRD)
.
20
EVIDENCE
THAT
LY-49A
INTERACTS
WITH
PEPTIDE
SEQUENCES
WITHIN
THE
A.
CHAIN
OF
CLASS
I
MHC
ANTIGENS
.
22
PATHWAYS
OF
INHIBITION
THROUGH
LY-49A
.
24
REFERENCES
.
25
SIGNAL
TRANSDUCTION
DURING
NK
CELL
ACTIVATION
J.D.
BONNEMA,
P.J.
LEIBSON,
ROCHESTER,
MINN
.
28
INTRODUCTION
.
28
FEY
RECEPTOR-INITIATED
SIGNALING
.
29
PROTEIN
TYROSINE
KINASES
(PTK)
.
31
PHOSPHOLIPASE
C-Y
(PLC-Y)
.
32
PHOSPHATIDYLINOSITOL
3-KINASE
(PI
3-KINASE)
.
32
RAS
.
33
TRANSCRIPTIONAL
REGULATION
.
33
SIGNAL
TRANSDUCTION
DURING
THE
GENERATION
OF
NATURAL
CYTOTOXICITY
.
34
INHIBITION
OF
NK
CELL
ACTIVATION
.
36
INHIBITION
INDUCED
BY
MHC
CLASS
I
RECOGNITION
.
37
NK
CELL
INACTIVATION
AND
APOPTOSIS
.
37
CONCLUSIONS
.
38
REFERENCES
.
39
NATURAL
KILLER
CELLS
IN
MHC
CLASS
I
DEFICIENT
MICE
M.
SALCEDO,
H.-G.
LJUNGGREN,
STOCKHOLM
.
44
INTRODUCTION
.
44
MHC
CLASS
I
DEFICIENT
MOUSE
MODELS
.
45
NUMBERS
OF
NK
CELLS
IN
MHC
CLASS
I
DEFICIENT
MICE
.
46
CYTOTOXIC
CAPACITY
OF
NK
CELLS
FROM
MHC
CLASS
I
DEFICIENT
MICE
.
47
NK
CELL-MEDIATED
ELIMINATION
OF
HEMATOPOIETIC
CELL
GRAFTS
FROM
MHC
CLASS
I
DEFICIENT
MICE
.
48
INABILITY
OF
NK
CELLS
TO
ELIMINATE
NONHEMATOPOIETIC
GRAFTS
FROM
MHC
CLASS
I
DEFICIENT
MICE
.
49
IN
VITRO
NK
CELL
CYTOTOXICITY
AGAINST
CELLS
DERIVED
FROM
MHC
CLASS
I
DEFICIENT
MICE
.
49
NK
CELLS
IN
MHC
CLASS
I
DEFICIENT
MICE
ARE
TOLERANT
TOWARDS
CLASS
I
DEFICIENT
BONE
MARROW
AND
FETAL
LIVER
GRAFTS,
AND
FAIL
TO
KILL
CLASS
I
DEFICIENT
CELLS
IN
VITRO
.
51
MHC
CLASS
I
DEFICIENT
MICE
FAIL
TO
REJECT
ALLOGENEIC
BONE
MARROW
GRAFTS
.
51
TRANSFER
OF
NK
SPECIFICITIES
IN
BONE
MARROW
CHIMERIC
MICE
.
52
NK
CELL-MEDIATED
RESISTANCE
TO
VIRUS
INFECTIONS
IN
MHC
CLASS
I
DEFICIENT
MICE
.
53
EXPRESSION
OF
NK
CELL
INHIBITORY
RECEPTORS
IN
MHC
CLASS
I
DEFICIENT
MICE
.
53
TAP
1
-/-,
P
2
M
-/
AND
TAP
L/0
2
M
-/
MICE
CAN
BE
USED
TO
ADDRESS
THE
ROLE
OF
INDIVIDUAL
MHC
CLASS
I
SUBUNITS
IN
NK
CELL
DEVELOPMENT
AND
TARGET
CELL
SENSITIVITY
.
54
COMPARISON
OF
STUDIES
IN
MHC
CLASS
I
DEFICIENT
MICE
WITH
RESULTS
GENERATED
IN
MHC
CLASS
I
TRANSGENIC
MICE
.
54
REJECTION
RESPONSES
AGAINST
BONE
MARROW
GRAFTS
FROM
MHC
CLASS
II
DEFICIENT
MICE
.
55
CONCLUSIONS
.
55
ACKNOWLEDGEMENTS
.
56
REFERENCES
.
56
CONTENTS
VI
ROLE
OF
THE
MAJOR
HISTOCOMPATIBILITY
COMPLEX
CLASS
I
REGIONS
IN
RAT
NATURAL
KILLER
CELL
ALLOGRAFT
RESPONSES
IN
VIVO
AND
IN
VITRO
B.
ROLSTAD,
OSLO
.
59
NK
RECEPTORS
FOR
MHC
MOLECULES,
'
STATE
OF
THE
ART
'
.
59
INHIBITORY
NK
RECEPTORS
FOR
CLASS
I
MOLECULES
.
59
'
ACTIVATORY
'
NK
CELL
RECEPTORS
.
60
STUDIES
OF
NK-MEDIATED
REJECTION
OF
LYMPHOCYTES
IN
VIVO
AND
IN
VITRO
SUGGEST
POSITIVE
RECOGNITION
OF
MHC
ANTIGENS
IN
RATS
.
61
CELL
SURFACE
MARKERS,
BIODISTRIBUTION,
ISOLATION
AND
FUNCTIONAL
TESTS
OF
RAT
NK
CELLS
.
62
CELL
SURFACE
MARKERS
.
62
BIODISTRIBUTION
.
66
ISOLATION
AND
TESTING
OF
RAT
ALLOREACTIVE
NK
CELLS
.
66
DESCRIPTION
OF
THE
RAT
MHC
(RT1)
REGIONS
RELEVANT
FOR
NK
ALLORECOGNITION
.
70
THE
ROLE
OF
CLASSICAL
(RT1.A)
VS.
NONCLASSICAL
(RT1.C)
CLASS
I
REGIONS
IN
DETERMINING
TARGET
SENSITIVITY
TO
ALLOREACTIVE
NK
CELLS
.
71
SUMMARY
AND
CONCLUDING
REMARKS
.
72
ACKNOWLEDGEMENT
.
73
REFERENCES
.
73
INHIBITORY
AND
ACTIVATORY
RECEPTORS
FOR
HLA
CLASS
I
MOLECULES
IN
HUMAN
NATURAL
KILLER
CELLS
A.
MORETTA,
BRESCIA;
M.
VITALE,
S.
SIVORI,
L.
MORELLI,
D.
PENDE,
C.
BOTTINO,
GENOA
.
77
HLA-C-SPECIFIC
INHIBITORY
RECEPTORS
ON
NK
CELLS
.
78
COEXPRESSION
OF
P58.1
AND
P58.2
RECEPTORS
.
79
ACTIVATORY
RECEPTORS
FOR
HLA-C
MOLECULES
.
80
NK
RECEPTORS
SPECIFIC
FOR
HLA-B
ALLOTYPES
.
81
HLA-A-SPECIFIC
NK
RECEPTORS
.
83
CONCLUDING
REMARKS
.
84
REFERENCES
.
85
MOLECULAR
STRUCTURES
OF
HLA-SPECIFIC
HUMAN
NK
CELL
RECEPTORS
C.
CANTONI,
S.
VERDIANI,
M.
FALCO,
R
CONTE,
R
BIASSONI,
GENOA
.
88
INTRODUCTION
.
88
NK
RECEPTORS
FOR
HLA-C
ALLELES
.
90
NK
RECEPTORS
FOR
HLA-B
ALLELES
.
94
NK
RECEPTORS
FOR
HLA-A
ALLELES
.
96
P58/P50-ASSOCIATED
MOLECULES
.
97
CONCLUDING
REMARKS
.
98
ACKNOWLEDGEMENTS
.
99
REFERENCES
.
100
CONTENTS
VII
NKB1:
A
KILLER
CELL
INHIBITORY
RECEPTOR
FOR
CLASS
I
HLA-B
ALLOTYPES
A.
D
'
ANDREA,
L.L.
LANIER,
PALO
ALTO,
CALIF.
.
104
INTRODUCTION
.
104
THE
MISSING
SELF
HYPOTHESIS
AND
NK
CELL
RECOGNITION
OF
MHC
CLASS
I
ALLELES
.
105
INHIBITORY
NK
CELL
RECEPTORS
FOR
MHC
CLASS
I
.
106
NKB1,
A
KILLER
CELL
INHIBITORY
RECEPTOR
FOR
HLA-B
.
108
HL
A
SPECIFICITY
OF
THE
NKB1
RECEPTOR
.
109
MOLECULAR
CLONING
OF
NKB1
.
109
NKB1
FUNCTION
ON
T
CELLS
.
ILL
THE
NK
CELL
REPERTOIRE
.
112
CONCLUSIONS
.
113
ACKNOWLEDGEMENT
.
113
REFERENCES
.
113
FUNCTIONAL
RESEMBLANCE
BETWEEN
THE
IG-RELATED
NK
CELL
RECEPTORS
SPECIFIC
FOR
HLA
CLASS
I
MOLECULES
AND
THE
CD94
C-TYPE
LECTIN
M.
LOPEZ-BOTET,
J.J.
PEREZ-VILLAR,
M.
CARRETERO,
A.
RODRIGUEZ,
I.
MELERO,
MADRID
.
116
INTRODUCTION
.
116
WHAT
DO
HUMAN
NK
CELL
RECEPTORS
'
SEE
'
ON
MHC
MOLECULES?
.
117
IG-RELATED
NK
CELL
RECEPTORS
.
118
HUMAN
NK
CELL
LECTIN-LIKE
RECEPTORS
.
121
NKG2
MOLECULES
.
121
HNKR-PLA
.
.
121
CD94
.
122
SOLUBLE
ANTI-CD94
MAB
INDUCES
ACTIVATION
OF
INTEGRIN-MEDIATED
ADHESION
IN
GROUP
B
NK
CELLS
.
128
CONCLUDING
REMARKS
.
131
ACKNOWLEDGEMENTS
.
131
REFERENCES
.
131
HLA-CLASS
I-SPECIFIC
INHIBITORY
RECEPTORS
OF
NK
TYPE
ON
A
SUBSET
OF
HUMAN
T
CELLS
M.C.
MINGARI,
C.
VITALE,
F.
SCHIAVETTI,
A.
CAMBIAGGI,
S.
BERTONE,
A.
ZUNINO,
M.
PONTE,
GENOA
.
135
EXPRESSION
OF
HLA-CLASS
I-SPECIFIC
NK
RECEPTORS
IN
PERIPHERAL
BLOOD
T
LYMPHOCYTES
.
136
HLA-CLASS
I-SPECIFIC
NK
RECEPTORS
ARE
EXPRESSED
BY
T
CELLS
WITH
A
MEMORY
PHENOTYPE
.
137
ANALYSIS
OF
THE
TCRVP
REPERTOIRE
IN
CD3
+
NK-R
+
T
LYMPHOCYTE
POPULATIONS
.
138
INHIBITORY
FUNCTION
AND
HLA-CLASS
I
SPECIFICITY
OF
NK-R
EXPRESSED
IN
T
CELLS
.
.
139
CONTENTS
VUJ
THE
NK-R
EXPRESSED
ON
CTL
INHIBIT
CELL
FUNCTIONS
TRIGGERED
VIA
THE
CD3/TCR
PATHWAY
.
139
EXPRESSION
OF
NK-R
IN
CD3
+
LYMPHOPROLIFERATIVE
DISEASES
OF
GRANULAR
LYMPHOCYTES
.
140
CONCLUDING
REMARKS
AND
FUTURE
PERSPECTIVES
.
141
ACKNOWLEDGEMENTS
.
142
REFERENCES
.
142
NK
CELLS
AND
CTL:
OPPOSITE
SIDES
OF
THE
SAME
COIN
N.M.
VALIANTE,
P.
PARHAM,
STANFORD,
CALIF.
.
146
INTRODUCTION
.
146
A
HISTORICAL
SEPARATION
.
147
FUNCTIONAL
AND
DEVELOPMENTAL
RELATIONSHIPS
BETWEEN
CTL
AND
NK
CELLS
.
148
CYTOTOXIC
LYMPHOCYTES:
CONVERGING
ON
MHC
CLASS
I?
.
151
EFFECTS
OF
MHC
CLASS
I
POLYMORPHISM
.
153
REPERTOIRE
DEVELOPMENT
.
155
ACTIVATION
VERSUS
INHIBITION
.
156
EVOLUTION
OF
COMPLEMENTARY
STRATEGIES
FOR
CMC
.
158
CONCLUSIONS
.
159
REFERENCES
.
160
ALLORECOGNITION
BY
MURINE
NATURAL
KILLER
CELLS:
STUDIES
WITH
BONE
MARROW
TRANSPLANTS
AND
LYSIS
OF
T
LYMPHOBLASTS
J.
LIU,
Y.Y.L.
YU,
K.
FISCHER
LINDAHL,
V.
KUMAR,
M.
BENNETT,
DALLAS,
TEX
.
164
INTRODUCTION
.
164
ROLE
OF
CLASS
I
MHC
MOLECULES
IN
HYBRID
RESISTANCE
TO
T
LYMPHOBLASTS
.
166
ROLE
OF
OTHER
MHC-ENCODED
MOLECULES
IN
ALLORECOGNITION
BY
NK
CELLS
.
175
ACKNOWLEDGEMENTS
.
179
REFERENCES
.
179
SUBJECT
INDEX
.
181
CONTENTS
IX |
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV011006210 |
| callnumber-first | Q - Science |
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| ctrlnum | (OCoLC)35110225 (DE-599)BVBBV011006210 |
| dewey-full | 616.07/9 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.07/9 |
| dewey-search | 616.07/9 |
| dewey-sort | 3616.07 19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV011006210 |
| illustrated | Illustrated |
| indexdate | 2024-08-14T00:24:36Z |
| institution | BVB |
| isbn | 3805563329 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007368917 |
| oclc_num | 35110225 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-355 DE-BY-UBR DE-12 DE-29 DE-91 DE-BY-TUM DE-578 |
| owner_facet | DE-19 DE-BY-UBM DE-355 DE-BY-UBR DE-12 DE-29 DE-91 DE-BY-TUM DE-578 |
| physical | XII, 184 S. Ill., graph. Darst. |
| publishDate | 1996 |
| publishDateSearch | 1996 |
| publishDateSort | 1996 |
| publisher | Karger |
| record_format | marc |
| series | Chemical immunology |
| series2 | Chemical immunology |
| spelling | Molecular basis of NK cell recognition and function vol. ed. L. Moretta Basel [u.a.] Karger 1996 XII, 184 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Chemical immunology 64 Killer Cells, Natural Killer cells HLA (DE-588)4160063-0 gnd rswk-swf Natürliche Killerzelle (DE-588)4171290-0 gnd rswk-swf MHC Klasse I (DE-588)4313494-4 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Natürliche Killerzelle (DE-588)4171290-0 s DE-604 Molekularbiologie (DE-588)4039983-7 s MHC Klasse I (DE-588)4313494-4 s HLA (DE-588)4160063-0 s Moretta, Lorenzo Sonstige oth Chemical immunology 64 (DE-604)BV002307222 64 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007368917&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular basis of NK cell recognition and function Chemical immunology Killer Cells, Natural Killer cells HLA (DE-588)4160063-0 gnd Natürliche Killerzelle (DE-588)4171290-0 gnd MHC Klasse I (DE-588)4313494-4 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| subject_GND | (DE-588)4160063-0 (DE-588)4171290-0 (DE-588)4313494-4 (DE-588)4039983-7 (DE-588)4143413-4 |
| title | Molecular basis of NK cell recognition and function |
| title_auth | Molecular basis of NK cell recognition and function |
| title_exact_search | Molecular basis of NK cell recognition and function |
| title_full | Molecular basis of NK cell recognition and function vol. ed. L. Moretta |
| title_fullStr | Molecular basis of NK cell recognition and function vol. ed. L. Moretta |
| title_full_unstemmed | Molecular basis of NK cell recognition and function vol. ed. L. Moretta |
| title_short | Molecular basis of NK cell recognition and function |
| title_sort | molecular basis of nk cell recognition and function |
| topic | Killer Cells, Natural Killer cells HLA (DE-588)4160063-0 gnd Natürliche Killerzelle (DE-588)4171290-0 gnd MHC Klasse I (DE-588)4313494-4 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| topic_facet | Killer Cells, Natural Killer cells HLA Natürliche Killerzelle MHC Klasse I Molekularbiologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007368917&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002307222 |
| work_keys_str_mv | AT morettalorenzo molecularbasisofnkcellrecognitionandfunction |