Interfacial phenomena in drug delivery and targeting:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Chur
Harwood Acad. Publ.
1995
|
| Schriftenreihe: | Drug targeting and delivery
5 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XXII, 289 S. Ill., graph. Darst. |
| ISBN: | 3718656337 |
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Datensatz im Suchindex
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| adam_text | INTERFACIAL PHENOMENA IN DRUG DELIVERY AND TARGETING GRAHAM BUCKTON
CENTRE FOR MATERIALS SCIENCE THE SCHOOL OF PHARMACY UNIVERSITY OF
LONDON, UK AP HARWOOD ACADEMIC PUBLISHERS AUSTRALIA * AUSTRIA * BELGIUM
* CHINA * FRANCE * GERMANY * INDIA JAPAN * MALAYSIA * NETHERLANDS *
RUSSIA * SINGAPORE * SWITZERLAND THAILAND * UNITED KINGDOM * UNITED
STATES CONTENTS PREFACE TO THE SERIES XIII INTRODUCTION XV LIST OF
SYMBOLS XVII PART A * FUNDAMENTALS CHAPTER 1: INTER FACIAL PHENOMENA,
SURFACE TENSION AND LIQUID/LIQUID INTERFACES 1.1 SURFACES AND INTERFACES
1 1.2 THE LIQUID/VAPOUR INTERFACE 2 1.2.1 THE MEASUREMENT OF SURFACE
TENSION 1.2.2 THE EFFECT OF ADDITIVES ON SURFACE TENSION 1.2.3 FOAMS
1.2.4 CONCLUDING COMMENTS ON THE LIQUID/VAPOUR INTERFACE 1.3 THE
LIQUID/LIQUID INTERFACE 10 1.3.1 STUDIES ON INSOLUBLE MONOLAYERS 1.3.2
EMULSIONS 1.3.2.1 THE BASIC CONCEPTS 1.3.2.2 EMULSION STABILITY 1.3.2.3
PHASES AND STABILISERS 1.3.3 CONCLUDING COMMENTS ON LIQUID/LIQUID
INTERFACES 1.4 THE PROPERTIES OF WATER 19 CHAPTER 2: THE SOLID/LIQUID
INTERFACE 2.1 THE SOLID SURFACE 27 2.1.1 SOLID SURFACE TENSION AND SOLID
SURFACE ENERGY 2.2 CRYSTALLINE AND AMORPHOUS MATERIALS 28 2.3 CONTACT
ANGLES 32 2.3.1 THE WETTING PROCESS 2.3.2 FACTORS WHICH AFFECT CONTACT
ANGLE 2.4 MEASUREMENT OF CONTACT ANGLES 39 2.4.1 CONTACT ANGLES ON
SMOOTH FLAT SURFACES 2.4.2 CAPILLARY PENETRATION 2.4.3 MEASUREMENT OF
CONTACT ANGLES FOR POWDERED SYSTEMS 2.4.3.1 THE DIFFICULTIES WITH
POWDERS 2.4.3.2 CONTACT ANGLES ON COMPACTS 2.4.3.3 LIQUID PENETRATION
EXPERIMENTS VU VIII CONTENTS 2.4.4 COMPARISON OF CONTACT ANGLE VALUES
OBTAINED FROM DIFFERENT TECHNIQUES 2.5 ESTIMATION OF SURFACE ENERGY
VALUES FOR SOLIDS 59 2.5.1 CRITICAL SURFACE TENSION, Y C 2.5.2 POLAR AND
DISPERSION COMPONENTS OF SURFACE ENERGY 2.5.2.1 THE NATURE OF
INTERFACIAL FORCES 2.5.2.2 CALCULATION OF POLAR AND DISPERSION FORCES
2.5.3 THEORY OF NON-ADDITIVE SURFACE ENERGY COMPONENTS 2.5.3.1
CALCULATION OF ACID-BASE SURFACE ENERGY PARAMETERS 2.5.4 EQUATION OF
STATE APPROACHES 2.6 ESTIMATING SURFACE ENERGIES BY USE OF IMMERSIONAL
CALORIMETRY 73 2.7 ADSORPTION AT THE SOLID/LIQUID INTERFACE 74 2.7.1
ISOTHERMS FOR THE ADSORPTION OF SOLUTE ONTO SOLID FROM SOLUTION 2.7.2
FACTORS WHICH AFFECT THE EXTENT OF ADSORPTION FROM SOLUTION 2.7.3
SIGNIFICANCE OF ADSORPTION AT THE SOLID/LIQUID INTERFACE CHAPTER 3: THE
SOLID/VAPOUR INTERFACE 3.1 THE BASIS OF ADSORPTION 83 3.2 CLEAN SURFACES
85 3.3 SOLID/VAPOUR ADSORPTION ISOTHERMS 86 3.3.1 THE LANGMUIR ISOTHERM
3.3.1.1 MATHEMATICAL DERIVATION OF THE LANGMUIR ISOTHERM 3.3.2 TYPE II,
III, IV AND V PHYSICAL ISOTHERMS 3.3.3 FREUDLICH ISOTHERM 3.3.4
BRUNAUER, EMMETT AND TELLER ISOTHERM 3.3.5 GAB ISOTHERM 3.3.6 POLANYI
ADSORPTION POTENTIAL 3.4 CAPILLARY CONDENSATION 94 3.5 THERMODYNAMICS OF
ADSORPTION 95 3.5.1 ISOSTERIC STUDIES 3.5.2 CALORIMETRIC STUDIES 3.5.2.1
AN INTRODUCTION TO ISOTHERMAL MICROCALORIMETRY 3.6 INTERACTIONS BETWEEN
POWDERS AND WATER VAPOUR 101 3.6.1 WATER ADSORPTION 3.6.2 WATER
ABSORPTION 3.6.3 TRANSFER OF WATER BETWEEN SOLIDS 3.6.4 DELIQUESCENCE
3.6.5 HYDRATES CONTENTS IX 3.7 REVERSE PHASE CHROMATOGRAPHY 108 3.7.1
ADSORPTION PARAMETERS AT ZERO COVERAGE 3.7.2 ADSORPTION ISOTHERMS
CHAPTER 4: OTHER INTERFACIAL PHENOMENA 4.1 SOLID/SOLID INTERFACES I 16
4.1.1 FRICTION 4.1.2 LUBRICATION 4.1.3 ADHESION 4.2 AEROSOLS 122 4.2.1
FORMATION OF AEROSOLS 4.3 RELATIONSHIPS BETWEEN INTERFACIAL PHENOMENA
AND OTHER PROPERTIES 124 4.3.1 TENSILE STRENGTH 4.3.2 SOLUBILITY
PARAMETER 129 4.4 ELECTRICAL ASPECTS OF INTERFACES 4.4.1 SOURCES OF
CHARGE ON MATERIALS 4.4.2 DLVO THEORY 4.5 SOME RELATIONSHIPS BETWEEN
INTERFACIAL PHENOMENA 133 CHAPTER 5: SURFACTANTS 5.1 TYPES OF SURFACTANT
138 5.2 MICELLES AND SURFACTANT AGGREGATION 5.2.1 MICELLE FORMATION
5.2.2 DETERMINATION OF THE CMC 5.2.3 FACTORS AFFECTING THE CMC 5.2.4
OTHER PHASE BEHAVIOUR 5.2.4.1 CONFORMATION BELOW THE CMC 5.2.4.2 CLOUD
POINT AND GEL FORMATION 144 5.3 PROPERTIES OF SURFACTANTS 5.3.1 WETTING
AGENTS 5.3.2 DETERGENCY 5.3.3 SOLUBILISATION 147 5.4 SURFACTANTS AS
STABILISERS OF EMULSIONS AND SUSPENSIONS 5.4.1 EMULSIONS 5.4.2
MICROEMULSIONS 5.4.3 EMULSION STABILITY 5.4.3.1 HLB SYSTEM 5.4.3.2 OTHER
STABILITY ASPECTS 151 5.5 SURFACTANTS AS STABILISERS OF SUSPENSIONS X
CONTENTS 5.6 NON-IONIC SURFACTANT VESICLES 154 5.7 NATURAL SURFACTANTS
155 5.7.1 IN THE GASTROINTESTINAL TRACT (BILE SALTS) 5.7.2 IN THE LUNG
AND EYE 5.8 SURFACTANT TOXICITY 157 PART B - PRACTICAL APPLICATIONS.
INTERFACIAL PHENOMENA IN PRODUCT DEVELOPMENT AND IN USE CHAPTER 6:
DEVELOPMENT ASPECTS 6.1 INTRODUCTION 165 6.2 SURFACE ENERGETIC
CONSIDERATIONS IN DEVELOPMENT OF SOLID DOSAGE FORMS 166 6.2.1 MIXING AND
EXCIPIENT INTERACTIONS 6.2.2 SPREADING OF BINDERS DURING WET GRANULATION
6.2.3 ADHESION OF FILM COATINGS TO TABLETS 6.2.4 DRUG/DRUG AND
DRUG/CARRIER INTERACTIONS IN DRY POWDER INHALERS 6.3 SURFACE ENERGETIC
CONSIDERATIONS IN THE DEVELOPMENT OF OTHER DOSAGE FORMS 180 6.3.1
NON-AQUEOUS SUSPENSIONS (INHALATION AEROSOLS) 6.3.1.1 DISPERSION OF
SOLIDS TO FORM SUSPENSIONS 6.3.1.2 AGGREGATION OF PARTICLES IN METERED
DOSE INHALERS 6.3.1.3 ADHESION TO CONTAINER WALLS 6.3.2 AQUEOUS
SUSPENSIONS 6.3.3 PACKAGING 6.4 VARIABILITY OF SURFACES 187 6.4.1
COMMINUTION 6.4.2 SPRAY DRYING 6.4.3 FREEZE DRYING 6.4.4 MIXING 6.4.5
CONCLUDING COMMENTS: OPTIMISING SURFACES FOR IDEAL PROPERTIES CHAPTER 7:
WETTING, SOLUBILITY, DISSOLUTION AND ABSORPTION 7.1 INTRODUCTION 197 7.2
WETTABILITY AND SOLUBILITY 197 7.2.1 CONSIDERATIONS OF HOW ASPECTS OF
STRUCTURE RELATE TO WETTABILITY 7.2.2 CONSIDERATIONS OF HOW ASPECTS OF
STRUCTURE RELATE TO SOLUBILITY 7.2.3 RELATIONSHIPS BETWEEN WETTABILITY
AND SOLUBILITY 7.2.4 RELATIONSHIPS BETWEEN WETTABILITY AND THE RATE OF
SOLUTION CONTENTS XI 7.3 PARTITION 207 7.3.1 RELATIONSHIPS BETWEEN
WETTABILITY, SOLUBILITY AND PARTITION COEFFICIENT 7.3.2 WATER DRAGGING
EFFECTS 7.3.3 CHOICE OF SOLVENT AND THE COLLANDER EQUATION 7.4
ABSORPTION ACROSS BIOLOGICAL MEMBRANES 211 7.4.1 ABSORPTION FROM THE
GASTRO-INTESTINAL TRACT 7.4.1.1 GENERAL CONCEPTS 7.4.1.2 PARTICULATE
ABSORPTION 7.4.2 CONCLUDING COMMENTS CHAPTER 8: BIOADHESION AND
MUCOADHESION 8.1 INTRODUCTION TO BIOADHESION AND MUCOADHESION 8.1.1
EXAMPLES OF BIOADHESIVE SYSTEMS 225 8.2 INTERFACIAL MODELS OF
BIOADHESION 8.2.1 MODELLING MUCOADHESION USING SURFACE ENERGIES 8.2.2
INTERPENETRATION IN MUCOADHESION 233 8.3 APPROACHES TO THE TESTING OF
BIOADHESIVE PERFORMANCE 234 8.4 OCULAR INSERTS CHAPTER 9: INTERACTIONS
OF COLLOIDAL DELIVERY SYSTEMS WITH THE BIOLOGICAL ENVIRONMENT 9.1
BEHAVIOUR OF BIOLOGICAL COMPONENTS AT THE SOLID/LIQUID INTERFACE 237
9.1.1 FLEXIBLE POLYMERS 9.1.2 RIGID POLYMERS 9.1.3 INTERFACIAL
PREDICTIONS OF POLYMER ADSORPTION 9.1.4 ENTHALPY AND ENTROPY OF PROTEIN
ADSORPTION 250 9.2 FUNCTIONS OF PROTEIN ADSORPTION 251 9.3 TARGETING OF
COLLOIDAL PARTICLES 9.3.1 DESIRABLE SURFACE PROPERTIES TO PREVENT
OPSONISATION 9-4 APPROACHES FOR TARGETING MICROSPHERES TO DIFFERENT BODY
SITES 9-5 INTERACTIONS BETWEEN SURFACTANT COATED PARTICLES AND PLASMA
PROTEINS 266 273 9.6 THE STEALTH LIPOSOME I ., 2 7 5 INDEX
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| id | DE-604.BV010934207 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:01:19Z |
| institution | BVB |
| isbn | 3718656337 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007313682 |
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| physical | XXII, 289 S. Ill., graph. Darst. |
| publishDate | 1995 |
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| series | Drug targeting and delivery |
| series2 | Drug targeting and delivery |
| spelling | Buckton, Graham Verfasser aut Interfacial phenomena in drug delivery and targeting Graham Buckton Chur Harwood Acad. Publ. 1995 XXII, 289 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Drug targeting and delivery 5 Drug targeting gtt Geneesmiddelentransport gtt Grensvlakchemie gtt Drug delivery systems Drug targeting Interfaces (Physical sciences) Targeted drug delivery (DE-588)4302415-4 gnd rswk-swf Grenzflächenchemie (DE-588)4246080-3 gnd rswk-swf Wirkstofffreisetzung (DE-588)4190018-2 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf Grenzflächenchemie (DE-588)4246080-3 s Targeted drug delivery (DE-588)4302415-4 s DE-604 Wirkstofffreisetzung (DE-588)4190018-2 s Arzneimittel (DE-588)4003115-9 s Drug targeting and delivery 5 (DE-604)BV008243262 5 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007313682&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Buckton, Graham Interfacial phenomena in drug delivery and targeting Drug targeting and delivery Drug targeting gtt Geneesmiddelentransport gtt Grensvlakchemie gtt Drug delivery systems Drug targeting Interfaces (Physical sciences) Targeted drug delivery (DE-588)4302415-4 gnd Grenzflächenchemie (DE-588)4246080-3 gnd Wirkstofffreisetzung (DE-588)4190018-2 gnd Arzneimittel (DE-588)4003115-9 gnd |
| subject_GND | (DE-588)4302415-4 (DE-588)4246080-3 (DE-588)4190018-2 (DE-588)4003115-9 |
| title | Interfacial phenomena in drug delivery and targeting |
| title_auth | Interfacial phenomena in drug delivery and targeting |
| title_exact_search | Interfacial phenomena in drug delivery and targeting |
| title_full | Interfacial phenomena in drug delivery and targeting Graham Buckton |
| title_fullStr | Interfacial phenomena in drug delivery and targeting Graham Buckton |
| title_full_unstemmed | Interfacial phenomena in drug delivery and targeting Graham Buckton |
| title_short | Interfacial phenomena in drug delivery and targeting |
| title_sort | interfacial phenomena in drug delivery and targeting |
| topic | Drug targeting gtt Geneesmiddelentransport gtt Grensvlakchemie gtt Drug delivery systems Drug targeting Interfaces (Physical sciences) Targeted drug delivery (DE-588)4302415-4 gnd Grenzflächenchemie (DE-588)4246080-3 gnd Wirkstofffreisetzung (DE-588)4190018-2 gnd Arzneimittel (DE-588)4003115-9 gnd |
| topic_facet | Drug targeting Geneesmiddelentransport Grensvlakchemie Drug delivery systems Interfaces (Physical sciences) Targeted drug delivery Grenzflächenchemie Wirkstofffreisetzung Arzneimittel |
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