Polyps of the gastrointestinal tract:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1996
|
| Schriftenreihe: | Surgical oncology clinics of North America
5,3 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI S., S. 487 - 739 Ill. |
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| 245 | 1 | 0 | |a Polyps of the gastrointestinal tract |c John P. Welch, guest ed. |
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| 490 | 1 | |a Surgical oncology clinics of North America |v 5,3 | |
| 650 | 4 | |a Adenocarcinoma | |
| 650 | 4 | |a Adenomatous Polyposis Coli | |
| 650 | 4 | |a Colectomy | |
| 650 | 4 | |a Colorectal Neoplasms | |
| 650 | 4 | |a Laparotomy | |
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Datensatz im Suchindex
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| adam_text | POLYPS OF THE GASTROINTESTINAL TRACT
CONTENTS
Foreword xiii
Blake Cady
Preface xv
John P. Welch
Pathology Neoplastic and Non Neoplastic 487
Fiona Graeme Cook
Polyps of the gastrointestinal tract are common and often hard to
diagnose by endoscopic or gross examination. Biopsy or polypec
tomy enables diagnosis and prognostication. This article is by no
means encyclopedic, but attempts to discuss the pathology of the
more common intestinal polyps.
The Adenoma Carcinoma Sequence in Colorectal Neoplasia 513
Michael J. O Brien and David Gibbons
In this article the epidemiologic, pathologic, molecular, and clinical
evidence for the adenoma carcinoma sequence is reviewed. The
authors describe the morphologic evolution of the precursor ade¬
nomas, from the earliest discernible abnormality of the colon to
adenomas with advanced pathologic features, the factors that de¬
termine the risk of progression of adenomas to adenocarcinoma,
the molecular events that parallel or underlie the morphologic
changes, the outcome of clinical interventions that have tested this
hypothesis, and the time frame within which this progression is
likely to occur.
Epidemiology of Gastrointestinal Polyps 531
Judith S. Jacobson and Alfred I. Neugut
Associations between polyps and cancer of the gastrointestinal
tract have been fully documented for adenomatous polyps and
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA
VOLUME 5 • NUMBER 3 • JULY 1996 vii
cancer of the large bowel. The geographic, gender, and age distri¬
bution of colorectal adenomas parallels that of colorectal cancer
incidence, and individuals with a history of adenomas are at in¬
creased risk for metachronous adenomas and cancer. Observa¬
tional studies of risk factors for incident adenomas have found el¬
evated risk associated with dietary variables including: high fat,
low fiber, and low vegetable intake; family history; obesity; smok¬
ing; and other exposures, some of which also are associated with
cancer. Dietary intervention trials with adenoma recurrence as an
endpoint, however, have had little success. Screening with poly
pectomy has proved effective in reducing cancer incidence and
may change the epidemiology of colorectal cancer.
Screening Programs in the Population at Large
and in High Risk Groups 545
David T. Lush
Existing guidelines for colorectal cancer screening in standard risk
patients are reviewed, as well as the data on which they are based.
A family history of colorectal cancer or significant adenoma in¬
creases the risk above that of standard risk individuals. Risk as¬
sessment and surveillance in higher risk individuals are discussed.
The Clinical Features of the Hereditary
and Nonhereditary Polyposis Syndromes 553
Scott K. Kuwada and Randall W. Burt
The polyposis syndromes are rare familial and noninherited syn¬
dromes associated with intestinal as well as extraintestinal malig¬
nancies in many cases. Their recognition and classification are crit¬
ical in determining the appropriate management strategies.
Familial Polyposis Syndromes: Advances in Molecular
Genetic Characterization 569
Steven M. Powell
Many gastrointestinal polyposis syndromes have well defined clin¬
ical and histopathologic features. Recent advances in our ability to
analyze these syndromes at the genetic level have allowed for fur¬
ther characterization of these entities and their pathophysiology.
Elucidation of the underlying molecular genetic alterations that re¬
sult in the various forms of adenomatous polyposis syndromes has
been reported recently and is discussed in this article. Defining
these syndromes at the genetic level has important biologic and
practical implications.
Diagnosis and Management of Gastroduodenal Polyps 589
Carol Ann Burke and Rosalind U. van Stolk
Upper gastrointestinal polyps are rare but common in the gastro¬
intestinal polyposis syndromes. Although the majority of upper
Viii CONTENTS
gastrointestinal polyps have no prognostic importance, they must
be distinguished from the minority with an associated cancer risk.
Polyps and Polypoid Lesions of the Jejunum and Ileum:
Clinical Aspects 609
Barry A. Levine and Brian J. Kaplan
Polyps and polypoid lesion of the small intestine present a major
challenge to the surgeon. In contrast to similar lesions in the large
intestine, small bowel polyps present late in their course and are
difficult to diagnose. Small bowel tumors produce vague symp¬
toms and screening tests are poor. Most of these polyps are found
at autopsy or during exploration for another cause. In this article,
the authors outline the problem as well as discuss the diagnosis
and treatment options.
Benign Colorectal Polyps: Endoscopic Surveillance Guidelines
and Effects on Colorectal Cancer Risk 621
Donald F. Lum and Mark Lane Welton
The development of fiberoptic technology, specifically flexible sig
moidoscopy and colonoscopy, has lowered the mortality from co¬
lorectal cancer. Because colonoscopic screening of the entire pop¬
ulation is not practical, this procedure is reserved for populations
at high risk for developing colorectal cancer. This article discusses
the significance of finding benign colorectal polyps, reviews cur¬
rent screening and surveillance techniques, gives specific recom¬
mendations for colonoscopic surveillance for adenomatous polyps,
and comments on whether surveillance impacts on the incidence
and mortality from colorectal cancer.
Endoscopic Management of Malignant Colorectal Polyps 633
Nicole J. Kafka and John A. Coller
Malignant polyps of the colorectum are increasingly identified en
doscopically. The management of these polyps depends on tech¬
nical, histologic, and patient factors. Prognostic criteria, including
margin of resection, depth of invasion, degree of differentiation,
and lymphovascular invasion, are evaluated by way of a review of
the existing literature. Technical issues are addressed. Treatment
options and the rationale for selecting options are discussed.
Complications of Endoscopic Polypectomy 663
Anthony M. Vernava III and Walter E. Longo
Colonoscopic polypectomy has revolutionized the treatment of be¬
nign colonic neoplasia. It is performed widely by gastroenterolo
gists and surgeons and is a safe procedure. The two major com¬
plications of colonoscopic polypectomy include hemorrhage which
CONTENTS ix
has a reported incidence of 0.2% to 3% and perforation which has
a reported incidence of 0.5% to 3%. Factors that increase the risk
of these complications and management strategies are discussed in
this review.
Operations for Familial Adenomatous Polyposis 675
Peter M. Sagar and John H. Pemberton
The purpose of this article is to discuss the advantages and dis¬
advantages of surgical procedures designed to eliminate the risk
of colorectal cancer, the surgical treatment of extracolonic polyps,
and the management of desmoid tumors.
Surgical Approaches to Benign and Malignant Tumors
of the Ampulla of Vater 689
Jaime A. Rivera, David W. Rattner, Carlos Fernandez del Castillo,
and Andrew L. Warshaw
Ampullary tumors include a diverse group of benign and malig¬
nant neoplasms. A surgical approach to their management was
initiated in 1899 by Halsted and continues to evolve. Surgical op¬
tions include a spectrum of operative procedures designed to re¬
lieve symptoms and to remove malignant or potentially malignant
tumors. This article discusses the issues relevant to ampullary tu¬
mor management with emphasis on the currently accepted and
controversial aspects of the surgical approach.
The Role of Laparoscopic Colectomy and Laparotomy
with Resection in the Management of Complex Polyps
of the Colon 713
Laurence R. Sands and Steven D. Wexner
Surgical options available to patients with endoscopically unre
sectable complex polyps of the colon include laparoscopic colec¬
tomy, laparotomy with segmental resection, and a combination of
techniques using the laparoscope and the colonoscope. The deci¬
sion of which method to use depends on the nature of the lesion
as well as the choice of both the patient and the surgeon. The sur¬
geon must be knowledgeable in all modes of therapy.
Surgical Excision of Large Rectal Villous Adenomas 723
Charles B. Whitlow, David E. Beck, and J. Byron Gathright
A significant percentage of villous tumors occur in the rectum.
These tumors have malignant potential, and complete excision
while maintaining anal sphincter function is the goal of treatment.
The surgical management of villous tumors of the rectum may be
X CONTENTS
accomplished by one of several transanal techniques, posterior ap¬
proaches, or intra abdominal operations depending on the location
and size of the tumor.
Index 735
Subscription Information Inside back cover
CONTENTS Xi
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| series | Surgical oncology clinics of North America |
| series2 | Surgical oncology clinics of North America |
| spelling | Polyps of the gastrointestinal tract John P. Welch, guest ed. Philadelphia [u.a.] Saunders 1996 XVI S., S. 487 - 739 Ill. txt rdacontent n rdamedia nc rdacarrier Surgical oncology clinics of North America 5,3 Adenocarcinoma Adenomatous Polyposis Coli Colectomy Colorectal Neoplasms Laparotomy Darmpolyp (DE-588)4224251-4 gnd rswk-swf Gastrointestinaltrakt (DE-588)4074445-0 gnd rswk-swf Polyposis (DE-588)4224242-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Darmpolyp (DE-588)4224251-4 s DE-604 Gastrointestinaltrakt (DE-588)4074445-0 s Polyposis (DE-588)4224242-3 s Welch, John P. Sonstige oth Surgical oncology clinics of North America 5,3 (DE-604)BV007071205 5,3 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007298700&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Polyps of the gastrointestinal tract Surgical oncology clinics of North America Adenocarcinoma Adenomatous Polyposis Coli Colectomy Colorectal Neoplasms Laparotomy Darmpolyp (DE-588)4224251-4 gnd Gastrointestinaltrakt (DE-588)4074445-0 gnd Polyposis (DE-588)4224242-3 gnd |
| subject_GND | (DE-588)4224251-4 (DE-588)4074445-0 (DE-588)4224242-3 (DE-588)4143413-4 |
| title | Polyps of the gastrointestinal tract |
| title_auth | Polyps of the gastrointestinal tract |
| title_exact_search | Polyps of the gastrointestinal tract |
| title_full | Polyps of the gastrointestinal tract John P. Welch, guest ed. |
| title_fullStr | Polyps of the gastrointestinal tract John P. Welch, guest ed. |
| title_full_unstemmed | Polyps of the gastrointestinal tract John P. Welch, guest ed. |
| title_short | Polyps of the gastrointestinal tract |
| title_sort | polyps of the gastrointestinal tract |
| topic | Adenocarcinoma Adenomatous Polyposis Coli Colectomy Colorectal Neoplasms Laparotomy Darmpolyp (DE-588)4224251-4 gnd Gastrointestinaltrakt (DE-588)4074445-0 gnd Polyposis (DE-588)4224242-3 gnd |
| topic_facet | Adenocarcinoma Adenomatous Polyposis Coli Colectomy Colorectal Neoplasms Laparotomy Darmpolyp Gastrointestinaltrakt Polyposis Aufsatzsammlung |
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