QSAR and drug design: new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
1995
|
| Schriftenreihe: | Pharmacochemistry library
23 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 493 S. Ill., graph. Darst. |
| ISBN: | 044488615X |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1804125390617182208 |
|---|---|
| adam_text | IMAGE 1
PHARMACOCHEMISTRY LIBRARY
EDITOR: H. TIMMERMAN
VOLUME 23
QSAR AND
DRUG DESIGN: NEW DEVELOPMENTS AND APPLICATIONS BASED ON TOPICS PRESENTED
AT THE ANNUAL JAPANESE (QUANTITATIVE) STRUCTURE- ACTIVITY RELATIONSHIP
SYMPOSIUM AND THE BIENNIAL CHINA-JAPAN DRUG DESIGN AND DEVELOPMENT
CONFERENCE EDITED BY:
TOSHIO FUJITA
DEPARTMENT OF AGRICULTURAL CHEMISTRY, KYOTO UNIVERSITY, KYOTO, AND EMIL
PROJECT, FUJITSU KANSAI SYSTEMS LABORATORY, OSAKA, JAPAN
ELSEVIER
AMSTERDAM - LAUSANNE - NEW YORK - OXFORD - SHANNON - TOKYO 1995
IMAGE 2
XIII
CONTENTS
T FUJITA; PREFACE JX
SECTION I: THREE-DIMENSIONAL STRUCTURE-BASED DRUG DESIGN, MOLECULAR
MODELLING AND THREE-DIMENSIONAL QSAR.
1 A. ITAI, N. TOMIOKA, Y. KATO RATIONAL APPROACHES TO COMPUTER DRUG
DESIGN BASED ON DRUG-RECEPTOR INTERACTIONS 3
2 K. AKAHANE, H. UMEYAMA DRUG DESIGN BASED ON RECEPTOR MODELING USING A
SYSTEM BIOCES(E) 49
3 T. MATSUZAKI, H. UMEYAMA, R. KIKUMOTO MECHANISMS OF THE SELECTIVE
INHIBITION OF THROMBIN, FACTOR XA, PLASMIN AND TRYPSIN 83
4 H. KOGA, M. OHTA THREE-DIMENSIONAL STRUCTURE-ACTIVITY RELATIONSHIPS
AND RECEPTOR MAPPING OF QUINOLONE ANTIBACTERIALS 97
5 M. YAMAKAWA, K. EZUMI, K. TAKEDA, T. SUZUKI, I. HORIBE, G. KATO, T
FUJITA CLASSICAL AND THREE-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY
ANALYSES OF STEROID HORMONES: STRUCTURE-RECEPTOR BINDING PATTERNS
OF ANTI-HORMONAL DRUG CANDIDATES 125
SECTION II: QUANTITATIVE STRUCTURE-PARAMETER ANALYSES AND
DATABASE-ORIENTED AND NEWER STATISTICAL (Q)SAR PROCEDURES AND DRUG
DESIGN.
6 C. YAMAGAMI, N. TAKAO, T FUJITA A N A L Y S IS A ND P R E D I C T I ON
OF 1 - O C T A N O L / W A T ER P A R T I T I ON C O E F F I C I E N TS
OF S U B S T I T U T ED D I A Z I N ES W I TH S U B S T I T U E NT A ND
S T R U C T U R AL P A R A M E T E RS . .. 1 53
7 M. AKAMATSU, T. FUJITA HYDROPHOBICITIES OF DI-TO PENTAPEPTIDES HAVING
UNIONIZABLE SIDE CHAINS AND CORRELATION WITH SUBSTITUENT AND STRUCTURAL
PARAMETERS . . 185
8 T. NISHIOKA, J. ODA ANALYSIS OF AMINO ACID SEQUENCE-FUNCTION
RELATIONSHIPS IN PROTEINS . 215
IMAGE 3
XIV
9 T. FUJITA, M. ADACHI, M. AKAMATSU, M. ASAO, H. FUKAMI, Y. INOUE,
I. IWATAKI, M.. KIDO, H. KOGA, T. KOBAYASHI, I. KUMITA, K. MAKINO, K.
ODA, A. OGINO, M. OHTA, F SAKAMOTO, T. SEKIYA, R. SHIMIZU, C. TAKAYAMA,
Y. TADA, I. UEDA, Y. UMEDA, M. YAMAKAWA, Y. YAMAURA, H. YOSHIOKA, M.
YOSHIDA, M. YOSHIMOTO, K. WAKABAYASHI
BACKGROUND AND FEATURES OF EMIL, A SYSTEM FOR DATABASE-AIDED
BIOANALOGOUS STRUCTURAL TRANSFORMATION OF BIOACTIVE COMPOUNDS . . . 235
10 /. MORIGUCHI, S. HIRONO FUZZY ADAPTIVE LEAST SQUARES AND ITS USE IN
QUANTITATIVE STRUCTURE- ACTIVITY RELATIONSHIPS 275
SECTION III: TRADITIONAL QSAR AND DRUG DESIGN.
11 Z.-R. GUO STRUCTURE-ACTIVITY RELATIONSHIPS IN MEDICINAL CHEMISTRY:
DEVELOPMENT OF DRUG CANDIDATES FROM LEAD COMPOUNDS 299
12 R.-L. LI, S.-Y. WANG CHEMICAL MODIFICATION AND STRUCTURE-ACTIVITY
RELATIONSHIP STUDIES OF PIPERINE AND ITS ANALOGS: AN EXAMPLE OF DRUG
DEVELOPMENT FROM FOLK MEDICINE 321
13 H. TERADA, S. GOTO, H. HORI, I. TAIRA STRUCTURAL REQUIREMENTS OF
LEUKOTRIENE ANTAGONISTS 341
14 K. MITANI QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS OF A NEW
CLASS OF CA 2+ -ANTAGONISTIC AND A-BLOCKING PHENOXYALKYLAMINE
DERIVATIVES . . . 369
15 H. OHTAKA APPLICATIONS OF QUANTITATIVE STRUCTURE-ACTIVITY
RELATIONSHIPS TO DRUG DESIGN OF PIPERAZINE DERIVATIVES 413
16 K. HASHIMOTO, H. TANII, A. HARADA, T. FUJITA QUANTITATIVE
STRUCTURE-ACTIVITY STUDIES OF NEUROTOXIC ACRYLAMIDE ANALOGS 451
SUBJECT INDEX 481
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| indexdate | 2024-07-09T18:00:48Z |
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| isbn | 044488615X |
| language | English |
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| physical | XIV, 493 S. Ill., graph. Darst. |
| publishDate | 1995 |
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| publisher | Elsevier |
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| series | Pharmacochemistry library |
| series2 | Pharmacochemistry library |
| spelling | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference ed. by Toshio Fujita Amsterdam [u.a.] Elsevier 1995 XIV, 493 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Pharmacochemistry library 23 Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf QSAR (DE-588)4205429-1 gnd rswk-swf (DE-588)1071861417 Konferenzschrift gnd-content QSAR (DE-588)4205429-1 s Arzneimittelentwicklung (DE-588)4143176-5 s DE-604 Fujita, Toshirō 1948- Sonstige (DE-588)135718074 oth Pharmacochemistry library 23 (DE-604)BV001899371 23 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007289646&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference Pharmacochemistry library Arzneimittelentwicklung (DE-588)4143176-5 gnd QSAR (DE-588)4205429-1 gnd |
| subject_GND | (DE-588)4143176-5 (DE-588)4205429-1 (DE-588)1071861417 |
| title | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference |
| title_auth | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference |
| title_exact_search | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference |
| title_full | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference ed. by Toshio Fujita |
| title_fullStr | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference ed. by Toshio Fujita |
| title_full_unstemmed | QSAR and drug design new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference ed. by Toshio Fujita |
| title_short | QSAR and drug design |
| title_sort | qsar and drug design new developments and applications based on topics presented at the annual japanese quantitative structure activity relationship symposium and the biennial china japanese drug design and development conference |
| title_sub | new developments and applications ; based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japanese Drug Design and Development Conference |
| topic | Arzneimittelentwicklung (DE-588)4143176-5 gnd QSAR (DE-588)4205429-1 gnd |
| topic_facet | Arzneimittelentwicklung QSAR Konferenzschrift |
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