Annexins: molecular structure to cellular function:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | German |
| Veröffentlicht: |
New York [u.a.]
Springer [u.a.]
1995
|
| Schriftenreihe: | Molecular biology intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | 245 S. Ill., graph. Darst. |
| ISBN: | 3540606335 0412102617 |
Internformat
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| 245 | 1 | 0 | |a Annexins: molecular structure to cellular function |c Barbara A. Seaton |
| 264 | 1 | |a New York [u.a.] |b Springer [u.a.] |c 1995 | |
| 300 | |a 245 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Molecular biology intelligence unit | |
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Annexins |x chemistry | |
| 650 | 4 | |a Annexins |x physiology | |
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Datensatz im Suchindex
| _version_ | 1808046358983081984 |
|---|---|
| adam_text |
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=
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CONTENTS
-
-
1.
ANNEXIN
GENE
STRUCTURE
.
1
NICHOLAS
J.
NEVID
AND
NELSON
D.
HORSEMAN
THE
ANNEXIN
REPEATS
.
2
N-TERMINAL
REGIONS
.
5
PROMOTER
REGIONS
.7
2.
ANNEXIN
V
MOLECULAR
STRUCTURE,
LIGAND
BINDING
AND
BIOLOGICAL
FUNCTION
.
15
BARBARA
A.
SEATON
THE
THREE
DIMENSIONAL
STRUCTURE
OF
ANNEXIN
V:
A
HISTORICAL
NOTE
.
15
THE
ANNEXIN
FOLD
.
17
ANNEXIN-LIGAND
BINDING
.
17
A
CA
2+
-DEPENDENT
TRANSITION
IN
DOMAIN
III
.
21
THE
ANNEXIN
SURFACE
IS
MOSTLY
HYDROPHILIC
.
22
PHOSPHOLIPID
BINDING
SITES
.
23
BINDING
OF
THE
PHOSPHOGLYCEROL
BACKBONE
TO
ANNEXIN
V
.23
COMPARISON
WITH
SECRETORY
PHOSPHOLIPASE
A
2
(SPLA
2
)
.
24
A
STRUCTURAL
BASIS
FOR
HEADGROUP
SPECIFICITY
.25
A
POSSIBLE
PS
RECOGNITION
SITE?
.25
ANNEXIN-MEMBRANE
BINDING
.
26
3.
THREE
DIMENSIONAL
STRUCTURE
OF
ANNEXIN
IV
.
31
R.
BRYAN
SUTTON
AND
STEPHEN
R
SPRANG
ANNEXIN
IV
CRYSTALLOGRAPHY
.
33
A
TYPICAL
ANNEXIN
FOLD
.
34
CALCIUM
BINDING
.35
STEREOCHEMISTRY
OF
CALCIUM
BINDING
.35
DOMAIN
III:
A
VARIABLE
DOMAIN
.
37
PHOSPHORYLATION
AT
THE
AMINO
TERMINUS
TERMINUS
.38
CONCLUSIONS
.39
4.
A
COMMON
TRIMER
OF
ANNEXIN
V
AS
A
BASIC
UNIT
IN
2D
AND
3D
CRYSTAL
FORMS
.
43
ALAIN
BRISSON
AND
ANITA
LEWIT-BENTLEY
TRIMERS
OF
MEMBRANE-BOUND
ANNEXIN
V
IN
2D
CRYSTALS
.
43
TRIMERS
OF
SOLUBLE
ANNEXINS
IN
3D
CRYSTALS
.
44
CONCLUSION
.
49
5.
A
MUTATIONAL
APPROACH
TO
ELUCIDATE
ANNEXIN
V
FUNCTION
.
53
BEGONA
CAMPOS,
JORGE
M.
NACIFFAND
JOHN
R.
DEDMAN
STRUCTURE-FUNCTION
ANALYSIS
.
54
ANALYSIS
OF
THE
ANNEXIN
V
AMINO-TERMINAL
REGION
.
54
PRODUCTION
OF
SITE-DIRECTED
ANNEXIN
V
MUTANTS
.55
BACTERIAL
EXPRESSION
AND
CHARACTERIZATION
OF
ANNEXIN
MUTANTS
.
56
IS
ANNEXIN
V
A CATION-SELECTIVE
VOLTAGE-GATED
CHANNEL?
.59
PERSPECTIVES:
THE
QUEST
TO
ELUCIDATE
THE
PHYSIOLOGICAL
FUNCTIONS
OF
ANNEXIN
V
.
60
6.
ANNEXINS
AND
MEMBRANE
TRAFFIC
.
67
VOLKER
GERKE
BIOCHEMICAL
PROPERTIES
OF
ANNEXINS:
PHOSPHOLIPID-BINDING,
VESICLE-AGGREGATION
AND
MEMBRANE-FUSION
.
68
STRUCTURAL
REQUIREMENTS
FOR
CA
2
7MEMBRANE
BINDING
.
69
INTRACELLULAR
DISTRIBUTION
AND
THE
PRESENCE
OF
ANNEXINS
ON
INTRACELLULAR
MEMBRANES
.
70
ANNEXINS
AND
EXOCYTOSIS
.
71
ANNEXINS
AND
ENDOCYTOSIS
.
74
OUTLOOK
.
75
7.
ANNEXIN
FUNCTIONS
IN
PHAGOCYTIC
LEUKOCYTES
.
81
JOEL
D.
ERNST
WHICH
ANNEXINS
ARE
PRESENT
IN
LEUKOCYTES?
.83
WHY
DOES
A
SINGLE
CELL
TYPE
EXPRESS
MULTIPLE
ANNEXINS?
.
85
FUNCTIONAL
STUDIES
OF
ANNEXINS
IN
LEUKOCYTES
.85
STUDIES
IN
CELL-FREE
SYSTEMS
.85
STUDIES
IN
PERMEABILIZED
CELLS
.
87
STUDIES
IN
INTACT
CELLS
.
88
HOW
DO
FINDINGS
IN
PHAGOCYTES
RELATE
TO
THOSE
IN
OTHER
CELLS?
.89
HOW
DO
FINDINGS
IN
OTHER
SYSTEMS
RELATE
TO
THE
FUNCTIONS
OF
ANNEXINS
IN
PHAGOCYTES?
.
92
HAVE
THE
CORRECT
PROTEINS
BEEN
IDENTIFIED?
ARE
ANNEXINS
NECESSARY
FOR
MEMBRANE
FUSION
IN
LEUKOCYTES?
.
92
FUTURE
DIRECTIONS
.
93
8.
ANNEXIN
BINDING
TO
LIPID
ASSEMBLIES
.
97
PAUL
MEERS
ANNEXIN
BINDING
TO
A
SINGLE
MEMBRANE
.
98
ANNEXIN
I
AS
A
CA
2+
-DEPENDENT
MEDIATOR
OF
MEMBRANE-MEMBRANE
CONTACT
.
109
9.
CA
2+
-INDEPENDENT
FUNCTIONS
OF
ANNEXINS
.
121
A.
LOUISE
UPTON,
HELENA
C.
EDWARDS
AND
STEPHEN
E.
MOSS
INTRACELLULAR
FUNCTIONS
FOR
THE
ANNEXINS
.122
ANNEXINS
AND
ENDOCYTOSIS
.
122
ENZYME
INHIBITION
BY
ANNEXINS
.
123
BINDING
OF
PL
1
TO ANNEXIN
II
.
124
CA
2+
-INDEPENDENT
MEMBRANE
ASSOCIATION
.
125
EXTRACELLULAR
FUNCTIONS
FOR
THE
ANNEXINS
.126
CELL
SURFACE
ANNEXINS
.
126
ANNEXINS
ARE
CELL
SURFACE
RECEPTORS
FOR
VIRUSES
.127
ANNEXINS
IN
EXTRACELLULAR
FLUIDS
.
128
CONCLUSIONS
.
128
10.
ANNEXIN/PROTEIN
INTERACTIONS:
CLUES
FOR
FUNCTION
.133
ADRIAN
SHELDON
AND
JAMES
M.
CHEN
INTRACELLULAR
ANNEXIN-BINDING
PROTEINS
.134
EXTRACELLULAR
ANNEXIN-BINDING
PROTEINS
.136
OTHER
ANNEXIN-BINDING
MOLECULES
.
138
11.
ANNEXIN
XI:
A
CALCYCLIN-ASSOCIATED
NUCLEAR
PROTEIN
.143
HIROYOSHI
HIDAKA
AND
NAOTO
MAMIYA
PURIFICATION
OF
A
CALCYCLIN-BINDING
PROTEIN
.
143
BIOCHEMICAL
FEATURES
OF
ANNEXIN
XI
.
144
GENERAL
PROPERTIES
OF
CALCYCLIN
.
145
PRIMARY
STRUCTURE
OF
ANNEXIN
XI
.146
TISSUE
DISTRIBUTION
OF
ANNEXIN
XI
.
146
ISOFORMS
OF
ANNEXIN
XI
.
150
CALCYCLIN-BINDING
SITE
OF
ANNEXIN
XI
.
150
ANNEXIN
XI
BINDING
SITE
OF
CALCYCLIN
.
152
NUCLEAR
LOCALIZATION
OF
ANNEXIN
XI
.
152
PHOSPHORYLATION
OF
ANNEXIN
XI
.
153
ANNEXIN
XI
AS
AN
AUTOANTIGEN
.
156
REGULATION
OF
SUBCELLULAR
DISTRIBUTION
OF
ANNEXIN
XI
.
156
NUCLEAR
LOCALIZATION
SEQUENCES
OF
ANNEXIN
XI
.156
12.
THE
BIOLOGY
OF
ANNEXIN
I
.
161
A.
AHLUWALIA,
J.
C.
BUCKINGHAM,
J.
D.
CROXTALL,
R.
J.
FLOWER,
N.
J.
GOULDING
AND
M.
PERRETTI
OTHER
REVIEWS
.162
GLUCOCORTICOID
INDUCTION
OF
ANNEXIN
I
.
163
THE
BIOLOGY
OF
ANNEXIN
1
.166
CONCLUSION
.
188
13.
ANNEXIN
V
AND
CELL
SURFACE-EXPRESSED
PHOSPHATIDYLSERINE:
A
REVEALING
PAS
DE
DEUX
.
201
CHRIS
P.M.
REUTELINGSPERGER
AND
WAANDER
L.
VAN
HEERDE
A
BRIEF
HISTORY
OF
ANNEXIN
V
.
201
THE
PHOSPHOLIPID
BINDING
PROPERTIES
OF
ANNEXIN
V
AS
ELUCIDATED
BY
MODEL
SYSTEMS
.
202
ANNEXIN
V
INTERACTION
WITH
THE
CELLULAR
MEMBRANE
.
203
ANNEXIN
V
RECOGNIZES
CELLS
WHICH
HAVE
SURFACE-EXPOSED
PS
AND
WHICH
ARE
IN
THE
TERMINAL
PHASE
OF
THEIR
EXISTENCE
.
204
ANNEXIN
V
AND
CELL
SURFACE-EXPRESSED
PS,
AN
EVOLUTIONARY
CONSERVED
PAS
DE
DEUX
?
.
206
14.
CLINICAL
APPLICATIONS
OF
ANNEXINS
.
213
JONATHAN
F.
TAIT
MEMBRANE
PHOSPHOLIPID
ASYMMETRY
.
213
PHOSPHOLIPID
BINDING
OF
ANNEXINS
.
214
IN
VITRO
STUDIES
.
214
IN
VIVO
STUDIES
.
216
FUTURE
PROSPECTS
.
218
15.
TRANSGENIC
MOUSE
MODELS:
STUDYING
THE
FUNCTION
OF
ANNEXIN
VI
IN
VIVO
.
221
ANN-MARIE
GUNTESKI-HAMBLIN
AND
JOHN
R.
DEDMAN
ANNEXIN
TRANSGENE
DESIGN
.
222
GENOTYPE
ANALYSIS
.
224
PHENOTYPE
ANALYSIS
.
225
FUTURE
DIRECTIONS
.
TEI
CONCLUSION
.
227
16.
NEMATODE
ANNEXINS
.
231
CARLE.
CREUTZ
ISOLATION
OF
A
NEMATODE
ANNEXIN
.
231
ADDITIONAL
NEMATODE
ANNEXIN
GENES
.
232
LOCALIZATION
OF
THE
MAJOR
NEMATODE
ANNEXIN
.
233
CONCLUSION
.
237
INDEX
.
239 |
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| dewey-sort | 3574.19 3245 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Book |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV010897651 |
| illustrated | Illustrated |
| indexdate | 2024-08-22T00:42:54Z |
| institution | BVB |
| isbn | 3540606335 0412102617 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007288155 |
| oclc_num | 181159623 |
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| owner_facet | DE-29 |
| physical | 245 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Springer [u.a.] |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spelling | Annexins: molecular structure to cellular function Barbara A. Seaton New York [u.a.] Springer [u.a.] 1995 245 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Literaturangaben Annexins chemistry Annexins physiology Lipocortins Molekulargenetik (DE-588)4039987-4 gnd rswk-swf Annexine (DE-588)4253644-3 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf Physiologie (DE-588)4045981-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Annexine (DE-588)4253644-3 s Molekulargenetik (DE-588)4039987-4 s DE-604 Zelle (DE-588)4067537-3 s Physiologie (DE-588)4045981-0 s Seaton, Barbara A. Sonstige oth DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007288155&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Annexins: molecular structure to cellular function Annexins chemistry Annexins physiology Lipocortins Molekulargenetik (DE-588)4039987-4 gnd Annexine (DE-588)4253644-3 gnd Zelle (DE-588)4067537-3 gnd Physiologie (DE-588)4045981-0 gnd |
| subject_GND | (DE-588)4039987-4 (DE-588)4253644-3 (DE-588)4067537-3 (DE-588)4045981-0 (DE-588)4143413-4 |
| title | Annexins: molecular structure to cellular function |
| title_auth | Annexins: molecular structure to cellular function |
| title_exact_search | Annexins: molecular structure to cellular function |
| title_full | Annexins: molecular structure to cellular function Barbara A. Seaton |
| title_fullStr | Annexins: molecular structure to cellular function Barbara A. Seaton |
| title_full_unstemmed | Annexins: molecular structure to cellular function Barbara A. Seaton |
| title_short | Annexins: molecular structure to cellular function |
| title_sort | annexins molecular structure to cellular function |
| topic | Annexins chemistry Annexins physiology Lipocortins Molekulargenetik (DE-588)4039987-4 gnd Annexine (DE-588)4253644-3 gnd Zelle (DE-588)4067537-3 gnd Physiologie (DE-588)4045981-0 gnd |
| topic_facet | Annexins chemistry Annexins physiology Lipocortins Molekulargenetik Annexine Zelle Physiologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007288155&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT seatonbarbaraa annexinsmolecularstructuretocellularfunction |