Recombinant DNA biotechnology III: the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France]
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
1996
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
782 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 569 S. Ill., zahlr. graph. Darst. |
| ISBN: | 0897669614 0897669622 |
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 782
May 15, 1996
RECOMBINANT DNA
BIOTECHNOLOGY III:
THE INTEGRATION OF BIOLOGICAL AND
ENGINEERING SCIENCES
Editors and Conference Organizers
Juan A. Asenjo, Matthias Reuss, Frank Schmidt, Charles Hershberger,
and Barbara A. Andrews
CONTENTS
Preface. By Juan A. Asenjo and Barbara A. Andrews x
Part I. Redirection of Primary and Secondary Metabolism
Coordination of Glycolysis and TCA Cycle Reaction Networks:
Citrate Glucose Cometabolism Eliminates Acids and Reveals Potential
Metabolic Engineering Strategies. By A. Goel, M. M. Domach,
William Hanley, J. W. Lee, and M. M. Ataai 1
Metabolic Engineering of Cephalosporin Biosynthesis in Streptomyces
clavuligerus. By ANURAG Khetan, Li Hong Malmberg, David H.
Sherman, and Wei Shou Hu 17
Construction of L Lysine , L Threonine , or L Isoleucine Overproducing
Strains of Corynebacterium glutamicum. By H. Sahm, L. Eggeling,
B. Eikmanns, and R. Kramer 25
Metabolic Engineering of Animal Cells. By Lena Haggstrom, Jan
Ljunggren, and Lars Ohman 40
Selection of a Succinoglycan Deficient Rhizobium meliloti Mutant Producing
a Partially Acetylated (1— 4) |} D Glucuronan: Symbiotic Properties
Analysis. By M. L. Gonzales, J. Courtois, A. Heyraud,
P. Colin Morel, P. Michaud, J. N. Barbotin, and B. Courtois 53
Diversified Shunt to the Production of Different Proportions of Secondary
Metabolites (Polyketides and Terpenes) Induced by Varying
Immobilization Constraints on Gibberella fujikuroi. By C. Roisin,
J. E. Nava Saucedo, and J. N. Barbotin 61
This volume is the result of a conference entitled Recombinant DNA Biotechnology III: The
Integration of Biological and Engineering Sciences, which was sponsored by the Engineering
Foundation and the European Science Foundation and held on October 16 through 21,1994 in
Deauville, France.
Part II. Protein Expression and Production in Eucaryotic Cells:
Transgenic Proteins
Gene Transfer and Amplification in CHO Cells: Efficient Methods for
Maximizing Specific Productivity and Assessment of Genetic
Consequences. By Florian M. Wurm, Adriana Johnson, Thomas
Ryll, Christiane Kohne, Harry Scherthan, Frank Glaab,
Yolanda S. Lie, Christos J. Petropoulos, and W. Robert
Arathoon 70
The argU Gene Product Enhances Expression of the Recombinant Human
a2 Interferon in Escherichia coli. By O. L. Garcia, B. Gonzalez,
A. Menendez, A. E. Sosa, J. R. Fernandez, H. Santana, and
N. Memeses 79
Rate Limitations in Posttranslational Processing by the Mammary Gland of
Transgenic Animals. By Anuradha Subramanian, Rekha K.
Paleyanda, Henryk Lubon, Barry L. Williams, Francis C.
GWAZDAUSKAS, JAMES W. KNIGHT, WILLIAM N. DROHAN, and WILLIAM
H. Velander 87
Construction of Gene Expression System in Cultured Tobacco Cells.
By A. Shinmyo, K. Yoshida, and T. Kasai 97
cw Regulatory Elements of the Peroxidase Gene in Arabidopsis thaliana
Involved in Root Specific Expression and Responsiveness to High Salt
Stress. By Chokchai Wanapu (Intapruk) and Atsuhiko Shinmyo 107
Part III. Protein Expression and Synthesis in Bacteria and Yeast
The Efficient Production of Human Epidermal Growth Factor by Bacillus
brevis. By Shogo Ebisu, Hiroaki Takagi, Kiyoshi Kadowaki, Hideo
Yamagata, and Shigezo Udaka 115
Production of a Malaria Transmission Blocking Protein from Recombinant
Yeast. By Min Ying Wang, David C. Kaslow, and Joseph Shiloach .... 123
Characteristics of Poly(3 Hydroxybutyric Acid) Synthesis by Recombinant
Escherichia coli. By Sang Yup Lee and Ho Nam Chang 133
Production of Antibody Fragments in Escherichia coli. By J. S. Harrison and
E. Keshavarz Moore 143
Environmental Dependence and Behavior Changes of a Recombinant
Escherichia coli. By J. Boudrant, A. Gschaedler, N. Robas, and
C. Branlant 159
Characterization of a Streptomyces rochei Endoglucanase. By Tiziana
Irdani, Brunella Perito, and Giorgio Mastromei 173
Optimization of Recombinant Gene Expression in Escherichia coli. By
DlETHARD MATTANOVICH, ROBERT WEIK, SILVIA THIM, WALTER
Kramer, Karl Bayer, and Hermann Katinger 182
Transport Mutants and Transport Genes of Corynebacterium glutamicum. By
L. Eggeling, R. Kramer, M. Vruic, W. Kronemeyer, and H. Sahm ... 191
A URA3 Promoter Deletion in a pYES Vector Increases the Expression
Level of a Fungal Lipase in Saccharomyces cerevisiae. By JENS SlGURD
Okkels 202
Maltodextrin Phosphorylase from Escherichia coli: Production and
Application for the Synthesis of a Glucose 1 Phosphate. By Bernd
Nidetzky, Andreas Weinhausel, Dietmar Haltrich, Klaus D.
Kulbe, and Reinhard Schinzel 208
Cloning and Expression of Thermostable Protease Gene from Bacillus
stearothermophilus HY 69 in Bacillus subtilis. By Shou Jun Yang, Cheng
Jin, Dong Hui Bao, and Shu Zheng Zhang 219
Protein Engineering of a Cephalosporin C Acylase from Pseudomonas Strain
N176.5y Yoshimasa Saito, Yoshinori Ishii, Takao Fujimura,
Hitoshi Sasaki, Yuji Noguchi, Hisashi Yamada, Mineo Niwa, and
Kyo Ichi Shimomura 226
Identification and Characterization of Cellulose Binding Domains in
Xylanase A of Clostridium stercorarium. By Kazuo Sakka, Goro
Takada, Shuichi Karita, and Kunio Ohmiya 241
Protein Expression in the Stressed Vibrio Strains. By Dezider Toth, Peter
Ferianc, Edita Karelova, and Bystri k Polek 252
Expression and Purification of Bovine Trophoblast Protein 1 (bTP 1) in
Escherichia coli. By T. S. Grewal, M. K. Jeacock, D. A. L. Shepherd,
and D. Sawa 264
Part IV. Bioprocessing Implications of Genetic Engineering: Bioreactor
Design, Operation, Control, and Environmental Biotechnology
Model Based Monitoring and Control of a Monoclonal Antibody Production
Process. By R. K. Biener, W. Waldraff, W. Noe, J. Haas,
M. Howaldt, and E. D. Gilles 272
Redox Balances in Recombinant Saccharomyces cerevisiae. By Barbel
Hahn Hagerdal, Johan Hallborn, Helena Jeppsson, Nina
Meinander, Mats Walfridsson, Heikki Ojamo, Merja Penttila,
Friedrich K. Zimmermann 286
Use of a Modified Tryptophanase Promoter to Direct High Level Expression
of Foreign Proteins in E. coli. By Karen C. Sitney, Michael B. Mann,
George W. Stearns, Anthony D. Menjares, Janice L. Stevenson,
Marshall D. Snavely, John C. Fieschko, Craig Curless, and
Larry B.Tsai 297
Stability of Plasmid pHV1431 in Free and Immobilized Cell Cultures: Effect
of Temperature. By Muriel Craynest, Jean Noel Barbotin, Nicole
Truffaut, and Daniel Thomas 311
Kinetic Studies for the Optimization of Recombinant Protein Formation. By
W. Kramer, G. Elmecker, R. WGik, D. Mattanovich, and K. Bayer .. 323
Mathematical Modeling of the Synthesis of a Cloned Lytic
P 1,4 Endoglucanase in Bacillus subtilis. By C. Shene, N. Mir,
B. A. Andrews, and J. A. Asenjo 334
Mathematical Modeling of Proteinase A Overproduction by Saccharomyces
cerevisiae. By Susanne Gr0n, Kirsten V/ever Jochumsen, Kirsten
Biedermann, and Claus Emborg 350
An Integrated Approach for Validating Cleaning Procedures in
Biopharmaceutical Manufacturing Facilities. By P. Inampudi,
S. LOMBARDO, G. RUEZINSKY, T. BALTRUS, J. DUGGER, P. REMSEN,
R. Rupp, and S. Nigam 363
Foam Fractionation of Proteins: Modeling of a Semi Batch Operation.
By F. Vazquez Lima and J. Varley 375
Bioprocessing with Genetically Modified and Other Organisms: Case Studies
in Processing Constraints. By Murray Moo Young, Yusuf Chisti,
Zhigen Zhang, Francisco Garrido, Uttam Banerjee, and Dagmar
Vlach 391
Recombinant DNA Technology in Development of an Economical
Conversion of Waste to Liquid Fuel. By A. L. Demain, T. R. Klapatch,
K. H. Jung, and L. R. Lynd 402
Part V. Purification and Refolding of Recombinant Proteins
Stabilization of Recombinantly Expressed Proteins. By Finn Matthiesen,
Kim R. Hejn/es, and Lars Skriver 413
Protein Purification in Preparative Scale of Mammalian Cell Culture
Derived Products: Strategies for Extra High Purity. By G. Mitra,
M. Wong, J. Bettencourt, G. Tsay, and P. Ng 422
Aseptic Chromatography Processing: Dream or Reality? By Sylvio BenGIO,
Hans Lettner, and Alois Jungbauer 432
Implementation in an Expert System of a Selection Rationale for Purification
Processes for Recombinant Proteins. By Eduardo W. Leser, Maria
Elena Lienqueo, and Juan A. Asenjo 441
Interactions of HIV 1 Proteins with Human T Cell Cyclophilin A. By Franz
Hammerschmid, Andreas Billich, Erich Wasserbauer, and
Brigitte Rosenwirth 456
The Use of Antibodies for Characterization and Quantification of a
Recombinant Protein. By Margarita Sabater, Susanne Heilmann,
HANNE FR0KI/ER, KlRSTEN BlEDERMANN, and CLAUS EMBORG 462
Influence of a Global Deregulation of the Heat Shock Response on the
Expression of Heterologous Proteins in Escherichia coli. By Jeffrey G.
Thomas and Francois Baneyx 478
Chaperone Like Effect during in Vitro Refolding of Insulin Like Growth
Factor I Using a Solubilizing Fusion Partner. By Elisabet Samuelsson
and Mathias Uhlen 486
Improving Protein Refolding Yields by Minimizing Aggregation. By Julian
B. Chaudhuri, Boris Batas, and Andrew D. Guise 495
Improved Refolding of a Matrix Bound Fusion Protein. By Gunter
Stempfer and Rainer Rudolph 506
Part VI. Recent Innovations in Bioprocessing and Molecular Biology
Carbon Carbon Bond Synthesis: The Impact of rDNA Technology on the
Production and Use of E. coli Transketolase. By M. D. Lilly,
R. Chauhan, C. French, M. Gyamerah, G. R. Hobbs, A. Humphrey,
M. Isupov, J. A. Littlechild, R. K. Mitra, K. G. Morris,
M. Rupprecht, N. J. Turner, J. M. Ward, A. J. Willetts, and
J. M. Woodley 513
RNA Libraries and RNA Recognition. By Francis J. Schmidt, Bongrae
Cho, and Hugh B. Nicholas, Jr 526
The Use of Recombinant DNA Technology in the Design of a Highly Specific
Heroin Sensor. By Deborah A. Rathbone, Peter John Holt, Neil C.
Bruce, and Christopher R. Lowe 534
T Cell Targeted Immunofusion Proteins from E. coll By Marc Better 544
Molecular Cloning of a Lytic (3 1,3 Glucanase Gene from Oerskovia
xanthineolytica LLG109: A (3 1,3 Glucanase Able to Selectively
Permeabilize the Yeast Cell Wall. By P. Ferrer, L. Hedegaard,
T. Halkier, I. Diers, D. Savva, and J. A. Asenjo 555
Index of Contributors 567
Financial assistance was received from:
• AMGEN, INC.
• BOEHRINGER MANNHEIM DIAGNOSTICS
• EUROPEAN COMMUNITY (EC)
• GENENTECH, INC.
• GLAXO RESEARCH AND DEVELOPMENT, LTD.
• INUAL SANTIAGO, CHILE
• LILLY RESEARCH LABORATORIES
• MERCK RESEARCH LABORATORIES
• MILES, INC.
• NOVO NORDISK
• PHARMACIA BIOTECHNOLOGY
• PHYTON CATALYTIC, INC.
• SCHERING PLOUGH
• XOMA CORPORATION
The New York Academy of Sciences believes it has a responsibility to provide an
open forum for discussion of scientific questions. The positions taken by the
participants in the reported conferences are their own and not necessarily those of
the Academy. The Academy has no intent to influence legislation by providing such
forums.
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| spelling | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] ed. by Juan A. Asenjo ... New York, NY New York Acad. of Sciences 1996 XI, 569 S. Ill., zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 782 Rekombinante DNS (DE-588)4225578-8 gnd rswk-swf Biotechnologie (DE-588)4069491-4 gnd rswk-swf Gentechnologie (DE-588)4071722-7 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1994 Deauville gnd-content Rekombinante DNS (DE-588)4225578-8 s Biotechnologie (DE-588)4069491-4 s DE-604 Gentechnologie (DE-588)4071722-7 s Asenjo, Juan A. Sonstige oth Annals of the New York Academy of Sciences 782 (DE-604)BV002532608 782 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007277477&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] Annals of the New York Academy of Sciences Rekombinante DNS (DE-588)4225578-8 gnd Biotechnologie (DE-588)4069491-4 gnd Gentechnologie (DE-588)4071722-7 gnd |
| subject_GND | (DE-588)4225578-8 (DE-588)4069491-4 (DE-588)4071722-7 (DE-588)1071861417 |
| title | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] |
| title_auth | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] |
| title_exact_search | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] |
| title_full | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] ed. by Juan A. Asenjo ... |
| title_fullStr | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] ed. by Juan A. Asenjo ... |
| title_full_unstemmed | Recombinant DNA biotechnology III the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] ed. by Juan A. Asenjo ... |
| title_short | Recombinant DNA biotechnology III |
| title_sort | recombinant dna biotechnology iii the integration of biological and engineering sciences this volume is the result of a conference held on october 16 through 21 1994 in deauville france |
| title_sub | the integration of biological and engineering sciences ; [this volume is the result of a conference ... held on October 16 through 21, 1994 in Deauville, France] |
| topic | Rekombinante DNS (DE-588)4225578-8 gnd Biotechnologie (DE-588)4069491-4 gnd Gentechnologie (DE-588)4071722-7 gnd |
| topic_facet | Rekombinante DNS Biotechnologie Gentechnologie Konferenzschrift 1994 Deauville |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007277477&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002532608 |
| work_keys_str_mv | AT asenjojuana recombinantdnabiotechnologyiiitheintegrationofbiologicalandengineeringsciencesthisvolumeistheresultofaconferenceheldonoctober16through211994indeauvillefrance |