Recombinational repair of DNA damage:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Springer [u.a.]
1996
|
| Schriftenreihe: | Molecular biology intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 210 S. Ill., graph. Darst. |
| ISBN: | 3540609628 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804125324085035008 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
1. INTRODUCTION 1
1.1. TWO-STRAND DNA REPAIR: A HELP FROM SISTER, RECOMBINATION AND MODELS
1
1.2. WHY E. COLP. 23
1.3. DNA REPLICATION IN B. COLI 25
SUMMARY 28
2. RECA PROTEIN - HOMOLOGOUS PAIRING ACTIVITY 35
2.1. IN VIVO ROLES OF RECA PROTEIN IN E. COLI AND ITS DISTRIBUTION AMONG
OTHER BACTERIA 35
2.2. IN VITRO ACTIVITIES OF RECA 38
2.3. SUPERVISION OF RECA ACTIVITY 46
SUMMARY 50
3. THE SOS RESPONSE 57
3.1. THE SOS RESPONSE: THE STRATEGY AND THE TACTICS 57 3.2. A POSSIBLE
MECHANISM OF SOS INDUCTION 62
3.3. STRUCTURAL TRANSITIONS WITHIN RECA MONOMER AND REGULATION OF RECA
POLYMERIZATION BY OTHER PROTEINS 67 SUMMARY 71
4. DAUGHTER-STRAND GAP REPAIR 81
4.1. ORIENTATION: THE ORIGIN OF DAUGHTER-STRAND GAPS AND THEIR REPAIR 81
4.2. PRESYNAPTIC PHASE OF DSG-REPAIR: RECF, RECO AND RECR PROTEINS 83
4.3. RECA POLYMERIZATION: REPLISOME REACTIVATION 89 4.4. TOPOISOMERASE
REQUIREMENTS OF THE SYNAPSIS REACTION: DNA GYRASE AND TOPOISOMERASE I 90
4.5. POSTSYNAPTIC PHASE OF DSG-REPAIR: RUVA, RUVB AND RUVC PROTEINS 93
4.6. A BACK-UP REPAIR OF DAUGHTER-STRAND GAPS: TRANSLESION DNA SYNTHESIS
104
SUMMARY 106
IMAGE 2
5. DOUBLE-STRAND END REPAIR 121
5.1. THE ORIGIN OF DOUBLE-STRAND BREAKS AND DOUBLE-STRAND ENDS 121
5.2. AN OUTLINE OF DOUBLE-STRAND END REPAIR 124
5.3. RECBCD NUCLEASE PREPARES DOUBLE-STRAND ENDS FOR RECA POLYMERIZATION
129
5.4. TWO PATHWAYS FOR THE POSTSYNAPTIC PHASE IN THE DOUBLE-STRAND END
REPAIR 137
5.5. DOUBLE-STRAND END REPAIR BACK-UP: DEGRADATION IN THE ABSENCE OF
RECOMBINATIONAL REPAIR 145
5.6. DOUBLE-STRAND END REPAIR IN THE ABSENCE OF RECBCD ENZYME 147
5.7. DEMULTIMERIZATION OF THE CHROMOSOME AFTER DOUBLE-STRAND END REPAIR
151
SUMMARY 157
6. SINGLE-STRAND ANNEALING: THE ALTERNATIVE RECOMBINATIONAL REPAIR OF
DOUBLE-STRAND BREAKS 169
6.0. SINGLE-STRAND ANNEALING REPAIR OF DOUBLE-STRAND BREAKS 169 6.1. SSA
REPAIR - THE BACTERIOPHAGE PANACEA 171
6.2. EXPERIMENTAL SET-UPS IN WHICH SSA REPAIR LOOKS LIKE DOUBLE-STRAND
END REPAIR 173
SUMMARY 179
7. RECOMBINATIONAL REPAIR IN EUKARYOTES 185
7.0. GENERAL RESPONSE OF EUKARYOTIC CELLS TO DNA DAMAGE 185 7.1.
ORGANIZATION OF RECOMBINATIONAL REPAIR IN YEAST, SACCHAROMYCES
CEREVISIAE 187
7.2. RECOMBINATIONAL REPAIR IN HIGHER EUKARYOTES 193 SUMMARY 198
CONCLUSION 205
SELECTED READING 206
INDEX 207
|
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| author | Kuzminov, Andrei |
| author_facet | Kuzminov, Andrei |
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| author_sort | Kuzminov, Andrei |
| author_variant | a k ak |
| building | Verbundindex |
| bvnumber | BV010836883 |
| classification_rvk | WG 3270 |
| classification_tum | BIO 180f BIO 220f |
| ctrlnum | (OCoLC)75765914 (DE-599)BVBBV010836883 |
| discipline | Biologie |
| format | Book |
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| illustrated | Illustrated |
| indexdate | 2024-07-09T17:59:45Z |
| institution | BVB |
| isbn | 3540609628 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007243743 |
| oclc_num | 75765914 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-M49 DE-BY-TUM |
| owner_facet | DE-355 DE-BY-UBR DE-M49 DE-BY-TUM |
| physical | 210 S. Ill., graph. Darst. |
| publishDate | 1996 |
| publishDateSearch | 1996 |
| publishDateSort | 1996 |
| publisher | Springer [u.a.] |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spelling | Kuzminov, Andrei Verfasser aut Recombinational repair of DNA damage Andrei Kuzminov New York [u.a.] Springer [u.a.] 1996 210 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit DNS-Schädigung (DE-588)4150350-8 gnd rswk-swf DNS-Reparatur (DE-588)4150347-8 gnd rswk-swf Rekombination (DE-588)4049338-6 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf Genetik (DE-588)4071711-2 gnd rswk-swf DNS-Reparatur (DE-588)4150347-8 s Rekombination (DE-588)4049338-6 s Genetik (DE-588)4071711-2 s DE-604 Zelle (DE-588)4067537-3 s DNS-Schädigung (DE-588)4150350-8 s SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007243743&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Kuzminov, Andrei Recombinational repair of DNA damage DNS-Schädigung (DE-588)4150350-8 gnd DNS-Reparatur (DE-588)4150347-8 gnd Rekombination (DE-588)4049338-6 gnd Zelle (DE-588)4067537-3 gnd Genetik (DE-588)4071711-2 gnd |
| subject_GND | (DE-588)4150350-8 (DE-588)4150347-8 (DE-588)4049338-6 (DE-588)4067537-3 (DE-588)4071711-2 |
| title | Recombinational repair of DNA damage |
| title_auth | Recombinational repair of DNA damage |
| title_exact_search | Recombinational repair of DNA damage |
| title_full | Recombinational repair of DNA damage Andrei Kuzminov |
| title_fullStr | Recombinational repair of DNA damage Andrei Kuzminov |
| title_full_unstemmed | Recombinational repair of DNA damage Andrei Kuzminov |
| title_short | Recombinational repair of DNA damage |
| title_sort | recombinational repair of dna damage |
| topic | DNS-Schädigung (DE-588)4150350-8 gnd DNS-Reparatur (DE-588)4150347-8 gnd Rekombination (DE-588)4049338-6 gnd Zelle (DE-588)4067537-3 gnd Genetik (DE-588)4071711-2 gnd |
| topic_facet | DNS-Schädigung DNS-Reparatur Rekombination Zelle Genetik |
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