Molecular basis of autoimmune hepatitis:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Springer [u.a.]
1996
|
| Schriftenreihe: | Medical intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 197 S. Ill., graph. Darst. |
| ISBN: | 3540608893 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV010801932 | ||
| 003 | DE-604 | ||
| 005 | 20240105 | ||
| 007 | t | ||
| 008 | 960619s1996 ad|| |||| 00||| eng d | ||
| 016 | 7 | |a 947898409 |2 DE-101 | |
| 020 | |a 3540608893 |9 3-540-60889-3 | ||
| 035 | |a (OCoLC)260205391 | ||
| 035 | |a (DE-599)BVBBV010801932 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-12 | ||
| 084 | |a YC 5622 |0 (DE-625)153237:12928 |2 rvk | ||
| 245 | 1 | 0 | |a Molecular basis of autoimmune hepatitis |c Ian G. McFarlane ; Roger Williams |
| 264 | 1 | |a New York [u.a.] |b Springer [u.a.] |c 1996 | |
| 300 | |a 197 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Medical intelligence unit | |
| 650 | 0 | 7 | |a Pathogenese |0 (DE-588)4115512-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Hepatitis |0 (DE-588)4024427-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Autoaggressionskrankheit |0 (DE-588)4003935-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Molekularpathologie |0 (DE-588)4170396-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Molekularbiologie |0 (DE-588)4039983-7 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Hepatitis |0 (DE-588)4024427-1 |D s |
| 689 | 0 | 1 | |a Autoaggressionskrankheit |0 (DE-588)4003935-3 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Hepatitis |0 (DE-588)4024427-1 |D s |
| 689 | 1 | 1 | |a Autoaggressionskrankheit |0 (DE-588)4003935-3 |D s |
| 689 | 1 | 2 | |a Pathogenese |0 (DE-588)4115512-9 |D s |
| 689 | 1 | 3 | |a Molekularbiologie |0 (DE-588)4039983-7 |D s |
| 689 | 1 | |5 DE-604 | |
| 689 | 2 | 0 | |a Hepatitis |0 (DE-588)4024427-1 |D s |
| 689 | 2 | 1 | |a Autoaggressionskrankheit |0 (DE-588)4003935-3 |D s |
| 689 | 2 | 2 | |a Molekularpathologie |0 (DE-588)4170396-0 |D s |
| 689 | 2 | |5 DE-604 | |
| 700 | 1 | |a McFarlane, Ian G. |e Sonstige |4 oth | |
| 700 | 1 | |a Williams, Roger |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007215940&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-007215940 | |
Datensatz im Suchindex
| _version_ | 1808227817248260096 |
|---|---|
| adam_text |
CONTENTS
1.
HISTORICAL
OVERVIEW
.
1
IAN
G.
MCFARLANE
AND
ROGER
WILLIAMS
I.
EARLY
DESCRIPTIONS
OF
THE
DISEASE
.
1
II.
MORPHOLOGY
AND
TERMINOLOGY
.
2
III.
IMMUNOLOGICAL
AND
IMMUNOGENETIC
FEATURES
OF
AIH
.
4
IV.
PATHOGENESIS
.
9
V.
THERAPY
.
11
VI.
INTERNATIONAL
AGREEMENT
ON
DIAGNOSTIC
CRITERIA
.
12
2.
NUCLEAR
ANTIGENS
.
23
JDZEFA
WESIERSKA-GADEK
AND
EDWARD
PENNER
I.
INTRODUCTION
.
23
II.
HISTONES
.25
III.
DNA
.
28
IV.
NUCLEAR
LAMINS
.
29
V.
OTHER
NUCLEAR
ANTIGENS
.
35
VI.
FUTURE
CONSIDERATIONS
.
40
3.
CYTOSKELETAL
ANTIGENS
.
45
DANIELA
ZAULI,
FABIO
CASSANI
AND
FRANCESCO
B.
BIANCHI
I.
INTRODUCTION
.
45
II.
SMOOTH
MUSCLE
ANTIBODY
(SMA)
.
48
III.
ANTI-INTERMEDIATE
FILAMENT
ANTIBODIES
.
53
IV.
ANTIMICROTUBULE
ANTIBODIES
.
54
V.
ANTILAMIN
ANTIBODIES
.
54
VI.
FUTURE
PERSPECTIVES
.
54
4.
CYTOPLASMIC
ANTIGENS
.59
MICHAEL
P.
MANNS
I.
INTRODUCTION
.
59
II.
AUTOANTIBODIES
TO
MICROSOMAL
ANTIGENS
OF
THE
LIVER
.
60
III.
LIVER-KIDNEY
MICROSOMAL
ANTIBODIES
TYPE
1
.
60
IV.
LIVER-KIDNEY
MICROSOMAL
ANTIBODIES
TYPE
2
(LKM2)
AND
CYTOCHROME
P450
IIC9
.
65
V.
LIVER
MICROSOMAL
ANTIBODIES
AND
CYTOCHROME
P450
IA2
.
66
VI.
UDP-GLUCURONOSYLTRANSFERASE
AND
MICROSOMAL
AUTOANTIBODIES
(LKM3)
IN
HEPATITIS
D
.
67
VIL
AUTOANTIBODIES
AGAINST
CYTOSOLIC
COMPONENTS
.
69
VIII.
CONCLUSIONS
AND
OUTLOOK
.
70
5.
HEPATOCELLULAR
MEMBRANE
ANTIGENS
.
75
BARBARA
M.
MCFARLANE
I.
BACKGROUND
.
75
II.
LIVER
MEMBRANE
ANTIGEN
.
76
III.
SULFATIDE
(CEREBROSIDE
SULFATE)
.
77
IV.
HUMAN
HEPATOCYTE
PLASMA
MEMBRANE
(HHPM)
ANTIGEN
.
78
V.
LIVER-SPECIFIC
MEMBRANE
LIPOPROTEIN
.
78
VI.
THE
ASIALOGLYCOPROTEIN
RECEPTOR
(ASGPR)
.
80
VIL
IMMUNE
REACTIONS
AGAINST
THE
ASIALOGLYCOPROTEIN
RECEPTOR
.
85
VIII.
CONCLUDING
REMARKS
.
91
6.
THE
IMMUNOGENETICS
OF
AUTOIMMUNE
HEPATITIS
IN
CAUCASOIDS
.
105
PETER
T.
DONALDSON,
MICHAEL
DJ.
STRETTELL,
LINDA
J.
THOMSON
I.
INTRODUCTION
.
105
II.
GENETIC
ORGANIZATION
OF
THE
MHC
.
105
III.
MOLECULAR
STRUCTURE
OF
HLA
CLASS
I
AND
CLASS
II
MOLECULES
.
109
IV.
CLINICAL
STUDIES
.
110
V.
POSSIBLE
MECHANISMS
OF
HLA-ENCODED
SUSCEPTIBILITY
TO
AIH
.
114
VI.
SUSCEPTIBILITY
VERSUS
SEVERITY
.
116
VIL
DIRECTIONS
FOR
FUTURE
STUDIES
.
117
7.
IMMUNOGENETICS
OF
AUTOIMMUNE
HEPATITIS
IN
JAPANESE
.
129
GOTARO
TODA
I.
INTRODUCTION
.
129
II.
CHARACTERISTICS
OF
AUTOIMMUNE
HEPATITIS
IN
JAPAN
.
130
III.
HLA
PHENOTYPES
IN
JAPANESE
AIH
PATIENTS
.
132
IV.
HLA
DNA
TYPING
IN
AIH
.
136
V.
CONCLUSION:
CLASSIFICATION
OF
AIH
BY
HLA
.
138
8.
PATHOGENETIC
MECHANISMS:
EVIDENCE
FROM
HUMAN
STUDIES
.
143
DIEGO
VERGANI
AND
GIORGINA
MIELI-VERGANI
I.
INTRODUCTION
.
143
II.
IMPAIRED
IMMUNOREGULATION
.
144
III.
AFFERENT
COMPONENT
OF
THE
AUTOIMMUNE
ATTACK
.
145
IV.
EFFERENT
COMPONENT
OF
THE
AUTOIMMUNE
ATTACK
.
146
V.
T
CELL
CLONING
.
147
VI.
SUMMARY
OF
CURRENT
KNOWLEDGE
.
148
VIL
FUTURE
RESEARCH
.
148
9.
THE
GERMAN
ANIMAL
MODELS
OF
AUTOIMMUNE
HEPATITIS
.
153
ANSGAR
W.
LOHSE
AND
KARL-HERMANN
MEYER
ZUM
BIISCHENFELDE
I.
INTRODUCTION
.
153
II.
CHRONIC
HEPATITIS
IN
RABBITS
.
154
III.
MURINE
EXPERIMENTAL
AUTOIMMUNE
HEPATITIS
(EAH)
.
155
IV.
CONCANAVALIN
A
INDUCED
HEPATITIS
.
159
V.
LESSONS
LEARNED
.
160
VI.
FUTURE
CONSIDERATIONS
.
161
10.
THE
JAPANESE
ANIMAL
MODELS
OF
AUTOIMMUNE
HEPATITIS
.165
HIROKI
TAKAHASHI
AND
MIKIO
ZENIYA
I.
INTRODUCTION
.
165
II.
EXPERIMENTAL
AUTOIMMUNE
HEPATITIS
(EAH)
IN
JAPAN
.
166
III.
OTHER
MODELS
.
172
IV.
CONSIDERATIONS
FOR
THE
FUTURE
.
173
11.
IMMUNOSUPPRESSIVE
DRUG
MECHANISMS
.
177
PHILIP
J.
JOHNSON
I.
INTRODUCTION
.
177
II.
DEVELOPMENT
OF
IMMUNOSUPPRESSIVE
REGIMENS
.
177
III.
MECHANISMS
OF
CORTICOSTEROID
ACTION
.
179
IV.
METABOLISM
AND
MECHANISMS
OF
ANTIPURINE
ACTION
.
182
V.
ACTION
OF
CORTICOSTEROIDS
AND
AZATHIOPRINE
IN
AIH
.
184
VI.
OTHER
IMMUNOSUPPRESSANTS
.
186
VIL
FUTURE
CONSIDERATIONS
.
186
INDEX
.
193 |
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV010801932 |
| classification_rvk | YC 5622 |
| ctrlnum | (OCoLC)260205391 (DE-599)BVBBV010801932 |
| discipline | Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nam a2200000 c 4500</leader><controlfield tag="001">BV010801932</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20240105</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">960619s1996 ad|| |||| 00||| eng d</controlfield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">947898409</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3540608893</subfield><subfield code="9">3-540-60889-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)260205391</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV010801932</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-12</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">YC 5622</subfield><subfield code="0">(DE-625)153237:12928</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Molecular basis of autoimmune hepatitis</subfield><subfield code="c">Ian G. McFarlane ; Roger Williams</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York [u.a.]</subfield><subfield code="b">Springer [u.a.]</subfield><subfield code="c">1996</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">197 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Medical intelligence unit</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pathogenese</subfield><subfield code="0">(DE-588)4115512-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Hepatitis</subfield><subfield code="0">(DE-588)4024427-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Autoaggressionskrankheit</subfield><subfield code="0">(DE-588)4003935-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Molekularpathologie</subfield><subfield code="0">(DE-588)4170396-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Molekularbiologie</subfield><subfield code="0">(DE-588)4039983-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Hepatitis</subfield><subfield code="0">(DE-588)4024427-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Autoaggressionskrankheit</subfield><subfield code="0">(DE-588)4003935-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Hepatitis</subfield><subfield code="0">(DE-588)4024427-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Autoaggressionskrankheit</subfield><subfield code="0">(DE-588)4003935-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="2"><subfield code="a">Pathogenese</subfield><subfield code="0">(DE-588)4115512-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="3"><subfield code="a">Molekularbiologie</subfield><subfield code="0">(DE-588)4039983-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="2" ind2="0"><subfield code="a">Hepatitis</subfield><subfield code="0">(DE-588)4024427-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="2" ind2="1"><subfield code="a">Autoaggressionskrankheit</subfield><subfield code="0">(DE-588)4003935-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="2" ind2="2"><subfield code="a">Molekularpathologie</subfield><subfield code="0">(DE-588)4170396-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="2" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">McFarlane, Ian G.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Williams, Roger</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">DNB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007215940&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-007215940</subfield></datafield></record></collection> |
| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV010801932 |
| illustrated | Illustrated |
| indexdate | 2024-08-24T00:47:05Z |
| institution | BVB |
| isbn | 3540608893 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007215940 |
| oclc_num | 260205391 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-12 |
| owner_facet | DE-355 DE-BY-UBR DE-12 |
| physical | 197 S. Ill., graph. Darst. |
| publishDate | 1996 |
| publishDateSearch | 1996 |
| publishDateSort | 1996 |
| publisher | Springer [u.a.] |
| record_format | marc |
| series2 | Medical intelligence unit |
| spelling | Molecular basis of autoimmune hepatitis Ian G. McFarlane ; Roger Williams New York [u.a.] Springer [u.a.] 1996 197 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Medical intelligence unit Pathogenese (DE-588)4115512-9 gnd rswk-swf Hepatitis (DE-588)4024427-1 gnd rswk-swf Autoaggressionskrankheit (DE-588)4003935-3 gnd rswk-swf Molekularpathologie (DE-588)4170396-0 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Hepatitis (DE-588)4024427-1 s Autoaggressionskrankheit (DE-588)4003935-3 s DE-604 Pathogenese (DE-588)4115512-9 s Molekularbiologie (DE-588)4039983-7 s Molekularpathologie (DE-588)4170396-0 s McFarlane, Ian G. Sonstige oth Williams, Roger Sonstige oth DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007215940&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular basis of autoimmune hepatitis Pathogenese (DE-588)4115512-9 gnd Hepatitis (DE-588)4024427-1 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd Molekularpathologie (DE-588)4170396-0 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| subject_GND | (DE-588)4115512-9 (DE-588)4024427-1 (DE-588)4003935-3 (DE-588)4170396-0 (DE-588)4039983-7 (DE-588)4143413-4 |
| title | Molecular basis of autoimmune hepatitis |
| title_auth | Molecular basis of autoimmune hepatitis |
| title_exact_search | Molecular basis of autoimmune hepatitis |
| title_full | Molecular basis of autoimmune hepatitis Ian G. McFarlane ; Roger Williams |
| title_fullStr | Molecular basis of autoimmune hepatitis Ian G. McFarlane ; Roger Williams |
| title_full_unstemmed | Molecular basis of autoimmune hepatitis Ian G. McFarlane ; Roger Williams |
| title_short | Molecular basis of autoimmune hepatitis |
| title_sort | molecular basis of autoimmune hepatitis |
| topic | Pathogenese (DE-588)4115512-9 gnd Hepatitis (DE-588)4024427-1 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd Molekularpathologie (DE-588)4170396-0 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| topic_facet | Pathogenese Hepatitis Autoaggressionskrankheit Molekularpathologie Molekularbiologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007215940&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT mcfarlaneiang molecularbasisofautoimmunehepatitis AT williamsroger molecularbasisofautoimmunehepatitis |