Antidiabetic agents: recent advances in their molecular and clinical pharmacology
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London [u.a.]
Acad. Press
1996
|
| Schriftenreihe: | Advances in drug research
27 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Einzelaufnahme eines Zeitschr.-Bd. |
| Beschreibung: | XVIII, 236 S. Ill., graph. Darst. |
| ISBN: | 012013327X |
Internformat
MARC
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Datensatz im Suchindex
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| adam_text | ADVANCES IN DRUG RESEARCH VOLUME 27 EDITED BY BERNARD TESTA SCHOOL OF
PHARMACY, UNIVERSITY OF LAUSANNE LAUSANNE, SWITZERLAND AND URS A. MEYER
INSTITUTE OF PHARMACOLOGY UNIVERSITY OF BASEL, BASEL SWITZERLAND
ANTIDIABETIC AGENTS RECENT ADVANCES IN THEIR MOLECULAR AND CLINICAL
PHARMACOLOGY BY H. P. T. AMMON, H. U. HARING, M. KELLERER, H. LAUBE, L.
MOSTHAF, E. J. VERSPOHL AND M. A. WAHL IT* ACADEMIC PRESS HARCOURT BRACE
& COMPANY, PUBLISHERS LONDON SAN DIEGO NEW YORK BOSTON SYDNEY TOKYO
TORONTO (UU CONTENTS CONTRIBUTORS IX FOREWORD XI PREFACE XIII
ABBREVIATIONS XV INTRODUCTION 1 REGULATION OF GLUCOSE HOMOEOSTASIS 1
INTRODUCTION 3 2 EFFECT OF INSULIN DEFICIENCY 7 3 REGULATION OF GLUCOSE
HOMOEOSTATIS IN TYPE-I DIABETES MELLITUS (IDDM) 9 4 REGULATION OF
GLUCOSE HOMOEOSTASIS IN TYPE-II DIABETES MELLITUS (NIDDM) 13 CLINICAL
ASPECTS OF DIABETES MELLITUS 1 TYPE-I DIABETES MELLITUS 17 2 TYPE-II
DIABETES MELLITUS 21 MECHANISMS OF INSULIN ACTION 1 INSULIN ACTIONS .
_.. -. 25 2 INSULIN RECEPTOR 26 3 SIGNAL TRANSDUCTION 32 4 EFFECTOR
SYSTEMS OF INSULIN SIGNALS: A LIMITED SELECTION . . . . 42 THERAPEUTIC
USE OF INSULIN 1 CHEMISTRY 50 2 PREPARATIONS 50 3 APPLICATION OF
INSULINS 52 4 PHARMACOKINETICS 53 5 TOXIC EFFECTS 55 6 SIDE EFFECTS 55 7
CLINICAL STUDIES OF INSULIN-REPLACEMENT THERAPY 69 VI CONTENTS THE
SECRETORY MACHINERY OF INSULIN RELEASE 1 INTRODUCTION 77 2 ROUTE BY
WHICH INITIATORS AND MODULATORS REACH THE B-CELL . . 78 3 INITIATION OF
INSULIN SECRETION 79 4 MODULATION OF INSULIN SECRETION VIA ADENYLATE
CYCLASE AND PHOSPHOLIPASE C (PLC) 92 5 CONCEPT OF INITIATION AND
MODULATION OF INSULIN SECRETION . . . 106 COMPOUNDS ACTING ON INSULIN
SECRETION: SULPHONYLUREAS 1 CHEMICAL STRUCTURE 108 2 ACTIONS 108 3
PHARMACOKINETICS 117 4 TOXIC EFFECTS 121 5 SIDE EFFECTS 122 6
INTERACTION WITH OTHER DRUGS 127 7 CLINICAL STUDIES 129 COMPOUNDS ACTING
ON GLUCOSE UPTAKE: BIGUANIDES 1 CHEMISTRY 137 2 PHARMACOLOGY 138 3
PHARMACOKINETICS 142 4 TOXIC EFFECTS 144 5 SIDE EFFECTS 144 6
INTERACTIONS WITH OTHER DRUGS 146 7 CLINICAL STUDIES 146 COMPOUNDS
ACTING ON GLUCOSE ABSORPTION 1 GUAR 151 2 ACARBOSE 159 ALDOSE REDUCTASE
INHIBITORS AS NEW ANTIDIABETIC DRUGS 1 CHEMISTRY 171 2 FUNCTIONS OF
ALDOSE REDUCTASE 172 3 ACTION OF ALDOSE REDUCTASE INHIBITORS 173 4
PHARMACOKINETICS 175 5 PATHOLOGICAL CHANGES IN THE PHARMACOKINETICS 176
6 TOXIC AND SIDE EFFECTS 176 CONTENTS VII 7 INTERACTION WITH OTHER DRUGS
177 8 CLINICAL TRIALS / . 177 CONCLUSIONS : 179 REFERENCES 181 SUBJECT
INDEX 215 CUMULATIVE INDEX OF AUTHORS 229 CUMULATIVE INDEX OF TITLES 233
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| illustrated | Illustrated |
| indexdate | 2024-07-09T17:58:27Z |
| institution | BVB |
| isbn | 012013327X |
| language | English |
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| physical | XVIII, 236 S. Ill., graph. Darst. |
| publishDate | 1996 |
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| publisher | Acad. Press |
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| series2 | Advances in drug research |
| spelling | Antidiabetic agents recent advances in their molecular and clinical pharmacology by H. P. T. Ammon ... London [u.a.] Acad. Press 1996 XVIII, 236 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advances in drug research 27 Einzelaufnahme eines Zeitschr.-Bd. Hypoglycemic Agents pharmacology Antidiabetikum (DE-588)4002265-1 gnd rswk-swf Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Diabetes mellitus (DE-588)4070446-4 gnd rswk-swf Antidiabetikum (DE-588)4002265-1 s Pharmakotherapie (DE-588)4076066-2 s DE-604 Diabetes mellitus (DE-588)4070446-4 s Ammon, Hermann P. T. 1933- Sonstige (DE-588)12106137X oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007187475&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Antidiabetic agents recent advances in their molecular and clinical pharmacology Hypoglycemic Agents pharmacology Antidiabetikum (DE-588)4002265-1 gnd Pharmakotherapie (DE-588)4076066-2 gnd Diabetes mellitus (DE-588)4070446-4 gnd |
| subject_GND | (DE-588)4002265-1 (DE-588)4076066-2 (DE-588)4070446-4 |
| title | Antidiabetic agents recent advances in their molecular and clinical pharmacology |
| title_auth | Antidiabetic agents recent advances in their molecular and clinical pharmacology |
| title_exact_search | Antidiabetic agents recent advances in their molecular and clinical pharmacology |
| title_full | Antidiabetic agents recent advances in their molecular and clinical pharmacology by H. P. T. Ammon ... |
| title_fullStr | Antidiabetic agents recent advances in their molecular and clinical pharmacology by H. P. T. Ammon ... |
| title_full_unstemmed | Antidiabetic agents recent advances in their molecular and clinical pharmacology by H. P. T. Ammon ... |
| title_short | Antidiabetic agents |
| title_sort | antidiabetic agents recent advances in their molecular and clinical pharmacology |
| title_sub | recent advances in their molecular and clinical pharmacology |
| topic | Hypoglycemic Agents pharmacology Antidiabetikum (DE-588)4002265-1 gnd Pharmakotherapie (DE-588)4076066-2 gnd Diabetes mellitus (DE-588)4070446-4 gnd |
| topic_facet | Hypoglycemic Agents pharmacology Antidiabetikum Pharmakotherapie Diabetes mellitus |
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