Principles of protein X-ray crystallography:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | German |
| Veröffentlicht: |
New York ; Berlin ; Heidelberg ; Barcelona ; Budapest ; Hong Kon
Springer
1995
|
| Schriftenreihe: | Springer advanced texts in chemistry
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturverz. S. 295 - 299 |
| Beschreibung: | XIII, 311 S. Ill., graph. Darst. |
| ISBN: | 354094091X 038794091X |
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| 100 | 1 | |a Drenth, Jan |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Principles of protein X-ray crystallography |c Jan Drenth |
| 264 | 1 | |a New York ; Berlin ; Heidelberg ; Barcelona ; Budapest ; Hong Kon |b Springer |c 1995 | |
| 300 | |a XIII, 311 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Springer advanced texts in chemistry | |
| 500 | |a Literaturverz. S. 295 - 299 | ||
| 650 | 4 | |a Biokemi | |
| 650 | 4 | |a Krystallografi | |
| 650 | 4 | |a Molekylærbiologi | |
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Datensatz im Suchindex
| _version_ | 1807502284873007104 |
|---|---|
| adam_text |
CONTENTS
SERIES
PREFACE
.
V
PREFACE
.
VII
CHAPTER
1
CRYSTALLIZING
A
PROTEIN
.
1
1.1
INTRODUCTION
.
1
1.2
PRINCIPLES
OF
PROTEIN
CRYSTALLIZATION
.
1
1.3
CRYSTALLIZATION
TECHNIQUES
.
4
1.4
CRYSTALLIZATION
OF
LYSOZYME
.
7
1.5
A
PRELIMINARY
NOTE
ON
CRYSTALS
.
10
1.6
PREPARATION
FOR
AN
X-RAY
DIFFRACTION
EXPERIMENT
.
11
1.7
NOTES
.
15
SUMMARY
.
18
CHAPTER
2
X-RAY
SOURCES
AND
DETECTORS
.
19
2.1
INTRODUCTION
.
19
2.2
X-RAY
SOURCES
.
19
2.3
MONOCHROMATORS
.
29
2.4
INTRODUCTION
TO
CAMERAS
AND
DETECTORS
.
30
2.5
DETECTORS
.
32
2.6
THE
PRECESSION
CAMERA
.
38
2.7
THE
ROTATION
(OSCILLATION)
INSTRUMENT
.
46
2.8
ELECTRONIC
AREA
DETECTORS
.
50
SUMMARY
.
51
X
CONTENTS
CHAPTER
3
CRYSTALS
.
54
3.1
INTRODUCTION
.
54
3.2
SYMMETRY
.
59
3.3
POSSIBLE
SYMMETRY
FOR
PROTEIN
CRYSTALS
.
62
3.4
COORDINATE
TRIPLETS:
GENERAL
AND
SPECIAL
POSITIONS
.
63
3.5
ASYMMETRIC
UNIT
.
63
3.6
POINT
GROUPS
.
67
3.7
CRYSTAL
SYSTEMS
.
68
3.8
RADIATION
DAMAGE
.
70
3.9
CHARACTERIZATION
OF
THE
CRYSTALS
.
71
SUMMARY
.
72
CHAPTER
4
THE
THEORY
OF
X-RAY
DIFFRACTION
BY
A
CRYSTAL
.
74
4.1
INTRODUCTION
.
74
4.2
WAVES
AND
THEIR
ADDITION
.
75
4.3
A
SYSTEM
OF
TWO
ELECTRONS
.
78
4.4
SCATTERING
BY
AN
ATOM
.
82
4.5
SCATTERING
BY
A
UNIT
CELL
.
84
4.6
SCATTERING
BY
A
CRYSTAL
.
85
4.7
DIFFRACTION
CONDITIONS
.
86
4.8
RECIPROCAL
LATTICE
AND
EWALD
CONSTRUCTION
.
88
4.9
THE
TEMPERATURE
FACTOR
.
93
4.10
CALCULATION
OF
THE
ELECTRON
DENSITY
P
(X
Y
Z)
.
96
4.11
COMPARISON
OF
F(H
K
I)
AND
F(HKT)
.
100
4.12
SYMMETRY
IN
THE
DIFFRACTION
PATTERN
.
101
4.13
INTEGRAL
REFLECTION
CONDITIONS
FOR
CENTERED
LATTICES
.
105
4.14
THE
PROJECTION
OF
ELECTRON
DENSITY
ALONG
AN
AXIS
.
106
4.15
THE
INTENSITY
DIFFRACTED
BY
A
CRYSTAL
.
107
4.16
CHOICE
OF
WAVELENGTH,
SIZE
OF
UNIT
CELL,
AND
CORRECTION
OF
THE
DIFFRACTED
INTENSITY
.
113
SUMMARY
.
115
CHAPTER
5
AVERAGE
REFLECTION
INTENSITY
AND
DISTRIBUTION
OF
STRUCTURE
FACTOR
DATA
.
117
5.1
INTRODUCTION
.
117
5.2
AVERAGE
INTENSITY;
WILSON
PLOTS
.
120
5.3
THE
DISTRIBUTION
OF
STRUCTURE
FACTORS
F
AND
STRUCTURE
FACTOR
AMPLITUDES
|F|
.
122
SUMMARY
.
124
CONTENTS
XI
CHAPTER
6
SPECIAL
FORMS
OF
THE
STRUCTURE
FACTOR
.
125
6.1
INTRODUCTION
.
125
6.2
THE
UNITARY
STRUCTURE
FACTOR
.
125
6.3
THE
NORMALIZED
STRUCTURE
FACTOR
.
126
SUMMARY
.
128
CHAPTER
7
THE
SOLUTION
OF
THE
PHASE
PROBLEM
BY
THE
ISOMORPHOUS
REPLACEMENT
METHOD
.
129
7.1
INTRODUCTION
.
129
7.2
THE
PATTERSON
FUNCTION
.
130
7.3
THE
ISOMORPHOUS
REPLACEMENT
METHOD
.
137
7.4
EFFECT
OF
HEAVY
ATOMS
ON
X-RAY
INTENSITIES
.
142
7.5
DETERMINATION
OF
THE
HEAVY
ATOM
PARAMETERS
FROM
CENTROSYMMETRIC
PROJECTIONS
.
146
7.6
PARAMETERS
OF
HEAVY
ATOMS
DERIVED
FROM
ACENTRIC
REFLECTIONS
.
148
7.7
THE
DIFFERENCE
FOURIER
SUMMATION
.
150
7.8
ANOMALOUS
SCATTERING
.
153
7.9
THE
ANOMALOUS
PATTERSON
SUMMATION
.
157
7.10
THE
MATTHEWS
PATTERSON
SUMMATION
.
159
7.11
ONE
COMMON
ORIGIN
FOR
ALL
DERIVATIVES
.
161
7.12
THE
ROSSMANN
METHOD
.
165
7.13
OTHER
"
COMMON
ORIGIN
"
METHODS
.
166
7.14
REFINEMENT
OF
THE
HEAVY
ATOM
PARAMETERS
.
166
7.15
PROTEIN
PHASE
ANGLES
.
171
7.16
THE
REMAINING
ERROR
IN
THE
BEST
FOURIER
MAP
.
175
7.17
THE
SINGLE
ISOMORPHOUS
REPLACEMENT
METHOD
(SIR)
.
181
SUMMARY
.
181
CHAPTER
8
PHASE
IMPROVEMENT
.
183
8.1
INTRODUCTION
.
183
8.2
THE
OMIT
MAP
WITH
AND
WITHOUT
SIM
WEIGHTING
.
184
8.3
SOLVENT
FLATTENING
.
190
8.4
MOLECULAR
AVERAGING
.
193
8.5
HISTOGRAM
MATCHING
.
198
8.6
FURTHER
CONSIDERATIONS
CONCERNING
DENSITY
MODIFICATION
.
199
SUMMARY
.
200
CHAPTER
9
ANOMALOUS
SCATTERING
IN
THE
DETERMINATION
OF
THE
PROTEIN
PHASE
ANGLES
AND
THE
ABSOLUTE
CONFIGURATION
.
201
XII
CONTENTS
9.1
INTRODUCTION
.
201
9.2
PROTEIN
PHASE
ANGLE
DETERMINATION
WITH
ANOMALOUS
SCATTERING
.
201
9.3
IMPROVEMENT
OF
PROTEIN
PHASE
ANGLES
WITH
ANOMALOUS
SCATTERING
.
203
9.4
THE
DETERMINATION
OF
THE
ABSOLUTE
CONFIGURATION
.
205
9.5
MULTIPLE
WAVELENGTH
ANOMALOUS
DISPERSION
(MAD)
.
207
SUMMARY
.
212
CHAPTER
10
MOLECULAR
REPLACEMENT
.
213
10.1
INTRODUCTION
.
213
10.2
THE
ROTATION
FUNCTION
.
214
10.3
THE
TRANSLATION
FUNCTION
.
223
SUMMARY
.
234
CHAPTER
11
DIRECT
METHODS
.
235
SUMMARY
.
237
CHAPTER
12
LAUE
DIFFRACTION
.
238
12.1
INTRODUCTION
.
238
12.2
THE
ACCESSIBLE
REGION
OF
RECIPROCAL
SPACE
.
239
12.3
THE
MULTIPLET
PROBLEM
.
240
12.4
UNSCRAMBLING
OF
MULTIPLET
INTENSITIES
.
241
12.5
THE
SPATIAL
OVERLAP
PROBLEM
.
242
12.6
WAVELENGTH
NORMALIZATION
.
242
SUMMARY
.
244
CHAPTER
13
REFINEMENT
OF
THE
MODEL
STRUCTURE
.
246
13.1
INTRODUCTION
.
246
13.2
THE
METHOD
OF
LEAST
SQUARES
.
248
13.3
THE
PRINCIPLE
OF
THE
FAST
FOURIER
TRANSFORM
(FFT)
METHOD
.
253
13.4
SPECIFIC
REFINEMENT
METHODS
.
255
SUMMARY
.
267
CHAPTER
14
THE
COMBINATION
OF
PHASE
INFORMATION
.
268
14.1
INTRODUCTION
.
268
14.2
PHASE
INFORMATION
FROM
ISOMORPHOUS
REPLACEMENT
.
269
14.3
PHASE
INFORMATION
FROM
ANOMALOUS
SCATTERING
.
271
CONTENTS
XIII
14.4
PHASE
INFORMATION
FROM
PARTIAL
STRUCTURE
DATA,
SOLVENT
FLATTENING,
AND
MOLECULAR
AVERAGING
.
272
SUMMARY
.
273
CHAPTER
15
CHECKING
FOR
GROSS
ERRORS
AND
ESTIMATING
THE
ACCURACY
OF
THE
STRUCTURAL
MODEL
.
274
15.1
INTRODUCTION
.
274
15.2
R-FACTORS
.
274
15.3
THE
RAMACHANDRAN
PLOT
.
276
15.4
STEREOCHEMISTRY
CHECK
.
276
15.5
THE
3D-1D
PROFILE
METHOD
.
278
15.6
QUANTITATIVE
ESTIMATION
OF
THE
COORDINATE
ERROR
IN
THE
FINAL
MODEL
.
280
SUMMARY
.
285
APPENDIX
1
A
COMPILATION
OF
EQUATIONS
FOR
CALCULATING
ELECTRON
DENSITY
MAPS
.
286
APPENDIX
2
A
COMPILATION
OF
RELIABILITY
INDICES
.
289
APPENDIX
3
THE
VARIATION
IN
THE
INTENSITY
OF
X-RAY
RADIATION
.
293
REFERENCES
.
295
INDEX
.
301 |
| any_adam_object | 1 |
| author | Drenth, Jan |
| author_facet | Drenth, Jan |
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| author_sort | Drenth, Jan |
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| id | DE-604.BV010660950 |
| illustrated | Illustrated |
| indexdate | 2024-08-16T00:35:04Z |
| institution | BVB |
| isbn | 354094091X 038794091X |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007116633 |
| oclc_num | 464782924 |
| open_access_boolean | |
| owner | DE-91G DE-BY-TUM |
| owner_facet | DE-91G DE-BY-TUM |
| physical | XIII, 311 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Springer |
| record_format | marc |
| series2 | Springer advanced texts in chemistry |
| spelling | Drenth, Jan Verfasser aut Principles of protein X-ray crystallography Jan Drenth New York ; Berlin ; Heidelberg ; Barcelona ; Budapest ; Hong Kon Springer 1995 XIII, 311 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Springer advanced texts in chemistry Literaturverz. S. 295 - 299 Biokemi Krystallografi Molekylærbiologi Proteiner Proteine (DE-588)4076388-2 gnd rswk-swf Röntgenstrukturanalyse (DE-588)4137203-7 gnd rswk-swf Proteine (DE-588)4076388-2 s Röntgenstrukturanalyse (DE-588)4137203-7 s DE-604 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007116633&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Drenth, Jan Principles of protein X-ray crystallography Biokemi Krystallografi Molekylærbiologi Proteiner Proteine (DE-588)4076388-2 gnd Röntgenstrukturanalyse (DE-588)4137203-7 gnd |
| subject_GND | (DE-588)4076388-2 (DE-588)4137203-7 |
| title | Principles of protein X-ray crystallography |
| title_auth | Principles of protein X-ray crystallography |
| title_exact_search | Principles of protein X-ray crystallography |
| title_full | Principles of protein X-ray crystallography Jan Drenth |
| title_fullStr | Principles of protein X-ray crystallography Jan Drenth |
| title_full_unstemmed | Principles of protein X-ray crystallography Jan Drenth |
| title_short | Principles of protein X-ray crystallography |
| title_sort | principles of protein x ray crystallography |
| topic | Biokemi Krystallografi Molekylærbiologi Proteiner Proteine (DE-588)4076388-2 gnd Röntgenstrukturanalyse (DE-588)4137203-7 gnd |
| topic_facet | Biokemi Krystallografi Molekylærbiologi Proteiner Proteine Röntgenstrukturanalyse |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007116633&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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