The thrombospondin gene family:
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Buch |
| Sprache: | German |
| Veröffentlicht: |
New York [u.a.]
Springer [u.a.]
1995
|
| Schriftenreihe: | Molecular biology intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 191 S. Ill., graph. Darst. |
| ISBN: | 3540603999 1570593086 |
Internformat
MARC
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| 001 | BV010555205 | ||
| 003 | DE-604 | ||
| 005 | 20210914 | ||
| 007 | t | ||
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| 020 | |a 3540603999 |9 3-540-60399-9 | ||
| 020 | |a 1570593086 |9 1-57059-308-6 | ||
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| 100 | 1 | |a Adams, Josephine C. |e Verfasser |0 (DE-588)1241133441 |4 aut | |
| 245 | 1 | 0 | |a The thrombospondin gene family |c Josephine C. Adams ; Richard P. Tucker ; Jack Lawler |
| 264 | 1 | |a New York [u.a.] |b Springer [u.a.] |c 1995 | |
| 300 | |a 191 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Molecular biology intelligence unit | |
| 650 | 4 | |a Calcium-binding proteins | |
| 650 | 4 | |a Thrombospondins | |
| 650 | 0 | 7 | |a Thrombospondin |0 (DE-588)4327213-7 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Genfamilie |0 (DE-588)4212496-7 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Thrombospondin |0 (DE-588)4327213-7 |D s |
| 689 | 0 | 1 | |a Genfamilie |0 (DE-588)4212496-7 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Tucker, Richard P. |e Verfasser |4 aut | |
| 700 | 1 | |a Lawler, Jack |e Verfasser |4 aut | |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007036574&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-007036574 | |
Datensatz im Suchindex
| _version_ | 1808046567454670848 |
|---|---|
| adam_text |
CONTENTS
1.
AN
INTRODUCTION
TO
THE
THROMBOSPONDINS
.
1
2.
THE
PRIMARY
STRUCTURE
OF
THE
THROMBOSPONDINS
.
11
INTRODUCTION
.
11
THE
NH
2
-TERMINAL
DOMAIN
.
13
THE
INTERCHAIN
DISULFIDE
BONDS
.
15
THE
REGION
OF
HOMOLOGY
WITH
PROCOLLAGEN
.
15
THE
TYPE
1
REPEATS
.
22
THE
TYPE
2
REPEATS
.
27
THE
TYPE
3
REPEATS
.
28
THE
COOH-TERMINAL
DOMAIN
.
31
EVOLUTION
OF
THE
THROMBOSPONDIN
GENE
FAMILY
.
32
CONCLUSION
.
35
3.
THE
SECONDARY
AND
TERTIARY
STRUCTURE
OF
THE
THROMBOSPONDINS
.
43
MOLECULAR
WEIGHT
AND
SUBUNIT
NUMBER
.
43
POST-TRANSLATIONAL
MODIFICATIONS
.
44
ELECTRON
MICROSCOPY
OF
THE
THROMBOSPONDINS
.
45
SUBUNIT
ASSEMBLY
.
49
SULFHYDRYL-DEPENDENT
CONFORMATION
.
52
CONCLUSION
.53
4.
THE
STRUCTURE
AND
REGULATION
OF
THE THROMBOSPONDIN
GENES
.
57
INTRODUCTION
.
57
THE
STRUCTURE
OF
THE
THROMBOSPONDIN
GENES
.
59
THE
PROMOTER
REGIONS
OF
THROMBOSPONDIN
1
AND
-2
.
61
REGULATION
OF
THROMBOSPONDIN
1
.
66
CONCLUSION
.
68
5.
THROMBOSPONDINS
IN
THE
EXTRACELLULAR
MATRIX
DURING
DEVELOPMENT
AND
DISEASE
.
75
INTRODUCTION
.
75
THROMBOSPONDINS
IN
THE
EXTRACELLULAR
MATRIX
IN
VITRO
.
76
THE
DETECTION
OF
THROMBOSPONDINS
IN
ADULT AND
EMBRYONIC
TISSUES
.
77
THROMBOSPONDINS
AND
PATHOGENESIS
.
91
CONCLUSION
.
97
6.
MECHANISTIC
AND
FUNCTIONAL
ASPECTS
OF
THE
INTERACTIONS
OF
THROMBOSPONDINS
WITH
CELL
SURFACES
.
105
INTRODUCTION
.
105
THE
AMINO-TERMINAL
HEPARIN-BINDING
DOMAIN
.
107
THE
PROCOLLAGEN
HOMOLOGY
DOMAIN
.
114
THE
CENTRAL
DOMAIN:
THE
TYPE
1
AND
TYPE
2
REPEATS
.
115
THE
TYPE
3
REPEATS
.
122
THE
CARBOXY-TERMINAL
DOMAIN
.
123
THE
ROLE
OF
INTEGRINS
AS
THROMBOSPONDIN
RECEPTORS
.
126
THE
ROLE
OF
CD36
AS
A
THROMBOSPONDIN
1
BINDING
PROTEIN
.
128
MECHANISM
OF
CELL
ADHESION
TO
THROMBOSPONDIN
1
.
134
INTERACTION
OF
SOLUBLE
THROMBOSPONDIN
1
WITH
CELLS
.
139
FUNCTIONAL
ACTIVITIES
OF
OTHER
MEMBERS
OF
THE
THROMBOSPONDIN
GENE
FAMILY
.
142
THROMBOSPONDIN
1
AS
A
SIGNALING
MOLECULE:
CLUES
TO
THE
MECHANISMS
OF
MODULATION
OF
CELL
BEHAVIOR
.
144
7.
CONCLUSIONS
AND
FUTURE
PROSPECTS
.
159
ARE
THERE
MORE
THROMBOSPONDIN
GENES?
.
159
THROMBOSPONDIN
STRUCTURES
.
161
GENE
REGULATION
.
163
IS
THERE
REDUNDANCY
WITHIN
THE
THROMBOSPONDIN
GENE
FAMILY?
.
164
THROMBOSPONDIN
EXPRESSION:
INSIGHTS
FROM
PATHOLOGICAL
SITUATIONS?
.
166
FUNCTIONS
OF
THE
NOVEL
THROMBOSPONDINS
.
170
CELLULAR
INTERACTIONS
WITH
THROMBOSPONDIN
1
.
176
OTHER
"ANTI-WDHESIVE"
MOLECULES
.
179
OTHER
PROSPECTS
.
180
INDEX
.
189 |
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| author_facet | Adams, Josephine C. Tucker, Richard P. Lawler, Jack |
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| bvnumber | BV010555205 |
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| discipline | Biologie |
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| id | DE-604.BV010555205 |
| illustrated | Illustrated |
| indexdate | 2024-08-22T00:46:12Z |
| institution | BVB |
| isbn | 3540603999 1570593086 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007036574 |
| oclc_num | 488986584 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 191 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Springer [u.a.] |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spelling | Adams, Josephine C. Verfasser (DE-588)1241133441 aut The thrombospondin gene family Josephine C. Adams ; Richard P. Tucker ; Jack Lawler New York [u.a.] Springer [u.a.] 1995 191 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Calcium-binding proteins Thrombospondins Thrombospondin (DE-588)4327213-7 gnd rswk-swf Genfamilie (DE-588)4212496-7 gnd rswk-swf Thrombospondin (DE-588)4327213-7 s Genfamilie (DE-588)4212496-7 s DE-604 Tucker, Richard P. Verfasser aut Lawler, Jack Verfasser aut DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007036574&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Adams, Josephine C. Tucker, Richard P. Lawler, Jack The thrombospondin gene family Calcium-binding proteins Thrombospondins Thrombospondin (DE-588)4327213-7 gnd Genfamilie (DE-588)4212496-7 gnd |
| subject_GND | (DE-588)4327213-7 (DE-588)4212496-7 |
| title | The thrombospondin gene family |
| title_auth | The thrombospondin gene family |
| title_exact_search | The thrombospondin gene family |
| title_full | The thrombospondin gene family Josephine C. Adams ; Richard P. Tucker ; Jack Lawler |
| title_fullStr | The thrombospondin gene family Josephine C. Adams ; Richard P. Tucker ; Jack Lawler |
| title_full_unstemmed | The thrombospondin gene family Josephine C. Adams ; Richard P. Tucker ; Jack Lawler |
| title_short | The thrombospondin gene family |
| title_sort | the thrombospondin gene family |
| topic | Calcium-binding proteins Thrombospondins Thrombospondin (DE-588)4327213-7 gnd Genfamilie (DE-588)4212496-7 gnd |
| topic_facet | Calcium-binding proteins Thrombospondins Thrombospondin Genfamilie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007036574&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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