Intracellular protein transport and membrane biogenesis:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | German |
| Veröffentlicht: |
New York u.a.
Springer
1995
Austin Landes |
| Schriftenreihe: | Molecular biology intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | 174 S. Ill., graph. Darst. |
| ISBN: | 3540603239 1570593000 |
Internformat
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Datensatz im Suchindex
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|---|---|
| adam_text | MOLECUIAR
BIOLOGY
INTELLIGENCE
UNIT
INTRACELLULAR PROTEIN
TRANSPORT AND
MEMBRANE BIOGENESIS
Keith Yerner, Ph D
Jeanette Beers, B S
Pennsylvania State University
The Milton S Hershey Medical Center
Hershey, Pennsylvania, U S A
Springer
New York Berlin Heidelberg London Paris
Tokyo Hong Kong Barcelona Budapest
HG UNDES COMPANY
AUSTIN
CONTENTS
1 Introduction 1
1 1 Protein Transport 1
1 2 Translocation System Requirements 2
1 3 Protein Targeting 3
1 4 Translocation 5
1 5 Protein Import Defects 7
1 6 Mitochondrial Protein Import and Disease 7
1 7 Peroxisomal Assembly and Disease 8
2 Biological Membranes 15
2 1 Introduction 15
2 2 Lipids 17
2 3 Lipid Behavior 19
2 4 Membrane Fluidity 20
2 5 Membrane Proteins 21
2 6 Studying Lipid Bilayers 25
2 7 Membrane Organelle Isolation 26
3 Transport of Lipids into Membranes 29
3 1 Introduction 29
3 2 Mechanisms of Lipid Transport 31
3 3 Glycerophospholipids: Phosphatidylcholine 34
3 4 Glycerophospholipids: Phosphatidylinositol 36
3 5 Glycerophospholipids: Phosphatidylethanolamine 36
3 6 Glycerophospholipids: Phosphatidylserine 37
3-7 Sphingolipids 38
3 8 Cholesterol 39
3 9 Lipid Sorting 40
4 Protein Transport Across Membranes in Prokaryotes 47
4 1 Prokaryofic Membranes 47
4 2 Sec-Dependent Translocation
Across the Plasma Membrane 49
4 3 Sec-Independent Translocation
Across the Plasma Membrane 53
4 4 The Prokaryotic SRP 56
4 5 Asymmetric Insertion of Proteins into the Plasma Membrane 57
4 6 The Periplasm 59
4 7 Insertion of Proteins into the Outer Membrane 61
4 8 Signal Peptide-Dependent Protein Secretion 63
4 9 Signal Peptide-Independent Protein Secretion 65
5 Protein Transport into the Endoplasmic Reticulum 71
5 1 Overview 71
5 2 The Signal Recognition Particle (SRP) 73
5 3 SRP Targeting to the Endoplasmic Reticulum Membrane 74
5 4 SRP-Independent Targeting
to the Endoplasmic Reticulum 75
5 5 Membrane Proteins Involved in Translocation 76
5 6 Translocation Across the Endoplasmic Reticulum Membrane 77
5 7 Sublocalization of Proteins Destined
for the Endoplasmic Reticulum 78
5 8 Protein Folding in the Endoplasmic Reticulum 80
5 9 Conclusion 80
6 Vesicular Transport 87
6 1 Overview 87
6 2 Retention of Endoplasmic Reticulum Proteins 89
6 3 Transport Between the Endoplasmic Reticulum
and Golgi Apparatus 93
6 4 Transport Through the Golgi 95
6 5 Retention of Golgi Proteins 97
6 6 Lysosomal Pathway 99
6 7 Constitutive Secretion 100
6 8 Regulated Secretion 102
7 Protein Transport to Mitochondria (and Chloroplasts) 109
7 1 Introduction 109
7 2 Mitochondrial Precursors Ill
7 3 Translocation Across the Mitochondrial Membranes 112
7 4 The Role of Cytosolic Chaperones in Mitochondrial Import 115
7 5 Cotranslational vs Post-Translational Mitochondrial Import 116
7 6 Post-Translocational Events Within Mitochondria 120
7 7 Sublocalization of Precursors Within the Mitochondria 122
7 8 Chloroplast Precursors 125
7 9 Protein Import into Chloroplasts 125
7 10 Sublocalization of Chloroplast Proteins 126
8 Protein Transport into Peroxisomes 135
8 1 Introduction 135
8 2 Historical Perspective 136
8 3 Targeting of Peroxisomal Proteins 137
8 4 Peroxisomal Assembly Mutants 140
8 5 Peroxisomal Membrane Proteins
and Candidates for Import Receptors 141
8 6 Translocation Across the Peroxisomal Membrane 143
8 7 Post-Translocational Events 144
9 Protein Transport into the Nucleus 151
9 1 Introduction 151
9 2 Targeting: The Nuclear Localization Signal 151
9 3 Targeting: NLS Receptors 154
9 4 The Nuclear Pore Complex 155
9 5 Requirements for Transport 159
9 6 Regulation of Nuclear Import 160
9 7 Nuclear Export 161
9 8 Nucleolar Targeting 162
Index 171
|
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| discipline | Biologie |
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| id | DE-604.BV010555202 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T17:54:59Z |
| institution | BVB |
| isbn | 3540603239 1570593000 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007036572 |
| oclc_num | 613040563 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-11 DE-188 |
| owner_facet | DE-355 DE-BY-UBR DE-11 DE-188 |
| physical | 174 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Springer Landes |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spelling | Verner, Keith Verfasser aut Intracellular protein transport and membrane biogenesis Keith Verner ; Jeanette Beers New York u.a. Springer 1995 Austin Landes 174 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Literaturangaben Intrazellulärer Transport (DE-588)4313701-5 gnd rswk-swf Proteintransport (DE-588)4273577-4 gnd rswk-swf Biomembran (DE-588)4006884-5 gnd rswk-swf Biogenese (DE-588)4006799-3 gnd rswk-swf Biomembran (DE-588)4006884-5 s Intrazellulärer Transport (DE-588)4313701-5 s Proteintransport (DE-588)4273577-4 s DE-604 Biogenese (DE-588)4006799-3 s DE-188 Beers, Jeanette Verfasser aut HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007036572&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Verner, Keith Beers, Jeanette Intracellular protein transport and membrane biogenesis Intrazellulärer Transport (DE-588)4313701-5 gnd Proteintransport (DE-588)4273577-4 gnd Biomembran (DE-588)4006884-5 gnd Biogenese (DE-588)4006799-3 gnd |
| subject_GND | (DE-588)4313701-5 (DE-588)4273577-4 (DE-588)4006884-5 (DE-588)4006799-3 |
| title | Intracellular protein transport and membrane biogenesis |
| title_auth | Intracellular protein transport and membrane biogenesis |
| title_exact_search | Intracellular protein transport and membrane biogenesis |
| title_full | Intracellular protein transport and membrane biogenesis Keith Verner ; Jeanette Beers |
| title_fullStr | Intracellular protein transport and membrane biogenesis Keith Verner ; Jeanette Beers |
| title_full_unstemmed | Intracellular protein transport and membrane biogenesis Keith Verner ; Jeanette Beers |
| title_short | Intracellular protein transport and membrane biogenesis |
| title_sort | intracellular protein transport and membrane biogenesis |
| topic | Intrazellulärer Transport (DE-588)4313701-5 gnd Proteintransport (DE-588)4273577-4 gnd Biomembran (DE-588)4006884-5 gnd Biogenese (DE-588)4006799-3 gnd |
| topic_facet | Intrazellulärer Transport Proteintransport Biomembran Biogenese |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007036572&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT vernerkeith intracellularproteintransportandmembranebiogenesis AT beersjeanette intracellularproteintransportandmembranebiogenesis |