Dipeptidyl peptidase IV (CD26) in metabolism and the immune response:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Springer [u.a.]
1995
|
| Schriftenreihe: | Molecular biology intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 202 S. Ill., graph. Darst. |
| ISBN: | 3540601996 1570592942 |
Internformat
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| 245 | 1 | 0 | |a Dipeptidyl peptidase IV (CD26) in metabolism and the immune response |c Bernhard Fleischer |
| 264 | 1 | |a New York [u.a.] |b Springer [u.a.] |c 1995 | |
| 300 | |a 202 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Molecular biology intelligence unit | |
| 650 | 4 | |a Antigens, CD26 - immunology | |
| 650 | 4 | |a Antigens, CD26 - metabolism | |
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Datensatz im Suchindex
| _version_ | 1808137464100945920 |
|---|---|
| adam_text |
CONTENTS
1.
CATALYTIC
MECHANISM
OF
DIPEPTIDYL
PEPTIDASE
IV
.
1
HANS-ULRICH
DEMUTH,
JOCHEN
HEINS
INTRODUCTION
.
1
DP
IV
-A
SERINE
PEPTIDASE
EXHIBITING
UNUSUAL
CATALYTIC
PROPERTIES.
2
MECHANISTIC
CONSIDERATIONS
.
17
CONCLUSIONS
.
26
2.
STRUCTURAL
ORGANIZATION
OF
THE
DP
IV
GENE
AND
ITS
RELATIONSHIP
WITH
DPX
AND
FAPA
TRANSCRIPTS
.
37
DIDIER
MARGUET,
ANNE-MARIE
BERNARD,
FREDERIC
DAVID,
ICIAR
LAZARO-TRUEBA,
MICHEL
PIERRES
INTRODUCTION
.
37
BIOCHEMICAL
AND
MOLECULAR CHARACTERIZATION
OF
CD26
IN
HUMANS,
MICE
AND
RATS
.
38
ORGANIZATION
OF
THE
CD26
GENE
.
40
EXPRESSION
OF
DP
IV
.
43
THE
DP
IV-RELATED
PROTEINS
.
45
GENE
CHROMOSOMAL
ASSIGNMENT
OF
THE
DP
IV-RELATED
FAMILY
.
48
CONCLUDING
REMARKS
.
49
3.
FUNCTIONAL
ASPECTS
OF
THE
THREE
EXTRACELLULAR
DOMAINS
OF
DIPEPTIDYL
PEPTIDASE
FV:
CHARACTERIZATION
OF
GLYCOSYLATION
EVENTS,
OF
THE
COLLAGEN-BINDING
SITE
AND
OF
ENDOPEPTIDASE
ACTIVITY
.
55
WERNER
REUTTER,
OLIVER
BAUM,
KLEMENS
LOSTER,
HUA
FAN,
JENS
PETER
BORK,
KATHRIN
BERNT,
CHRISTOPH
HANSKI,
RUDOLF
TAUBER
INTRODUCTION
.
56
RESULTS
AND
DISCUSSION
.
58
4.
CONTROL
OF
DIPEPTIDYL
PEPTIDASE
IV/CD26
CELL
SURFACE
EXPRESSION
IN
INTESTINAL
CELLS
.
79
GERMAIN
TRUGNAN,
LAURENT
BARICAULT,
FR&TTRIC
DAVID,
MARTINE
GARCIA,
CATHERINE
SAPIN
INTRODUCTION
.
79
DP
IV
CELL
SURFACE
EXPRESSION
AS
A
FUNCTION
OF
ENTEROCYTIC
DIFFERENTIATION
IS
PRIMARILY
UNDER
THE
CONTROL
OF
A
POST-TRANSCRIPTIONAL
EVENT
.
82
METABOLIC
AND
HORMONAL
CELL
ENVIRONMENT
MAY
MODULATE
DP
IV
CELL
SURFACE
EXPRESSION
.
86
FUTURE
PROSPECTS
.
92
5.
MODULATION
AND
FUNCTIONAL
DIVERSITY
OF
DIPEPTIDYL
PEPTIDASE
IV
IN
MURINE
AND
HUMAN
SYSTEMS
.
99
BRIGITTE
BAUVOIS
INTRODUCTION
.
99
REGULATED
EXPRESSION
OF
DP
IV
.
99
DP
IV
AS
A REGULATORY
MOLECULE
.
102
DP
IV
AS
A CELL
ADHESION
MOLECULE
.
104
CONCLUSION
AND
FURTHER
CONSIDERATIONS
.
106
6.
ROLE
OF
DIPEPTIDYL
PEPTIDASE
IV
(DP
IV)
IN
INTESTINAL
AND
RENAL
ABSORPTION
OF
PEPTIDES
.
ILL
MATTHIAS
BRANDSCH,
VADIVEL
GANAPATHY,
FREDERICK
H.
LEIBACH
INTRODUCTION
.
ILL
DP
IV
ACTIVITY
IN
INTESTINAL
AND
RENAL
EPITHELIUM
.
112
PEPTIDE
SUBSTRATES
FOR
DP
IV
IN
THE
INTESTINE
AND
KIDNEY
.
113
H7PEPTIDE
COTRANSPORT
IN
INTESTINAL
AND
RENAL
EPITHELIUM
.
115
INVOLVEMENT
OF
DP
IV
IN
INTESTINAL
AND
RENAL
PEPTIDE
ABSORPTION
.
116
THE
F344
DP
IV-DEFICIENT
RAT
.
118
PEPTIDE
HYDROLYSIS
AND
PEPTIDE
TRANSPORT
IN
INTESTINAL
AND
RENAL
EPITHELIUM
OF
DP
IV-DEFICIENT
RATS
.
121
CONCLUSIONS
AND
FUTURE
DIRECTIONS
.
124
7.
CD26:
A
KEY
COSTIMULATORY
MOLECULE
INVOLVED
IN
CD4
MEMORY
T
CELL
FUNCTION
AND
ACTIVATION
.
131
CHIKAO
MORIMOTO,
STUART
F.
SCHLOSSMAN
INTRODUCTION
.
131
THE
STRUCTURE
OF
CD26
.
132
ASSOCIATION
MOLECULES
OF
CD26
AND
ITS
SIGNAL-INDUCING
ACTIVITY
.
133
DP
IV
ENZYME
ACTIVITY
AND
T
CELL
ACTIVATION
.
136
ENHANCEMENT
OF
ANTIGEN-INDUCED
T
CELL
PROLIFERATION
BY
SOLUBLE
CD26/DP
IV
.
136
POSSIBLE
INVOLVEMENT
OF
CD26
IN
HIV
INFECTION
AND
APOPTOSIS
.
139
CLOSING
REMARKS
.
140
8.
MOLECULAR
REQUIREMENTS
FOR
SIGNALING
THROUGH
THE
CD26
MOLECULE
IN
T
LYMPHOCYTES
.145
ARNE
VON
BONIN,
HANS-WILLI
MITTRIICKER,
BERNHARD
FLEISCHER
INTRODUCTION
.
145
STIMULATION
VIA
CD26
IS
TCR
DEPENDENT
.
146
THE
ROLE
OF
CD3
-CHAIN
IN
THE
STIMULATION
VIA
CD26
.
147
ROLE
OF
DIPEPTIDYL
PEPTIDASE
(DP
IV)
ACTIVITY
IN
T-CELL
ACTIVATION
.
149
CONCLUSIONS
.
150
9.
CD26,
A
T
CELL
ACCESSORY
MOLECULE
INDUCTION
OF
ANTIGEN-SPECIFIC
IMMUNE-SUPPRESSION
BY
INACTIVATION
OF
CD26:
A
CLUE
TO
THE
AIDS
PARADOX?
.
155
MEENA
SUBRAMANYAM,
WILLIAM
B.
BACHOVCHIN,
BRIGITTE
HUBER
ROLE
OF
CD26
AND
ITS
ASSOCIATED
ENZYMATIC
ACTIVITY
IN
T
CELL
ACTIVATION
AND
CLONAL
EXPANSION
.
156
THE
CD26/HIV-1
TAT
CONNECTION
.
158
PROBOROPRO
AND
HIV-1
TAT
BIND
TO
DISTINCT
EPITOPES
OF
THE
CD26
RECEPTOR
.
158
CONCLUSIONS
AND
IMPLICATIONS
.
159
10.
DP
IV/CD26
ON
HUMAN
LYMPHOCYTES:
FUNCTIONAL
ROLES
IN
CELL
GROWTH
AND
CYTOKINE
REGULATION
.
163
SIEGFRIED
ANSORGE,
FRANK
BIDDING,
TORSTEN
HOFFMANN,
THILO
KAHNE,
KLAUS
NEUBERT,
DIRK
REINHOLD
CD26/DP
IV
IS
NOT
ONLY
EXPRESSED
ON
LYMPHOCYTES
OF
THE
T
CELL
LINEAGE
.
164
MOLECULAR
FORMS
AND
SUBCELLULAR
LOCALIZATION
OF
DP
IV
ARE
CHANGED
AFTER
LYMPHOCYTE
ACTIVATION
.
166
DP
IV-SPECIFIC
INHIBITORS
DO
SUPPRESS
DNA
SYNTHESIS
AND
CYTOKINE
PRODUCTION
OF
LYMPHOCYTES
.
168
TGF-PL
MAY
PLAY
A
CRUCIAL
ROLE
IN
DP
IV
ACTION
.
170
THE
EFFECTS
OF
DP
IV
ANTIBODIES
ON
DNA
SYNTHESIS
DEPENDS
ON
ENZYMATIC
ACTIVITY
OF
DP
IV
.
172
DP
IV
AND
AP-N
CATALYZE
THE
HYDROLYSIS
OF
CYTOKINE
PEPTIDES
BUT
NOT
OF
INTACT
CYTOKINES
.
174
DP
IV
IS
DIRECTLY
INVOLVED
IN
EARLY
EVENTS
OF
SIGNAL
TRANSDUCTION
OF
LYMPHOCYTES
.
175
CONCLUSIONS
AND
DISCUSSION
.
177
11.
CD26
AS
A
FUNCTIONAL
MARKER
OF
TH1
LYMPHOCYTES
.
185
TAILA
MATTERN,
ARTUR
J.
ULMER,
DAGMAR
SCHEEL-TOELLNER,
HANS-DIETER
FLAD
TOWARDS
THE
DEFINITION
OF
THE
CD26
ANTIGEN
.
185
EXPRESSION
OF
CD26
(DP
IV)
ON
HUMAN
T
LYMPHOCYTES
.
187
CD26
A
MARKER
OF
ACTIVATED
T
CELLS,
BUT
NOT
SPECIFIC
FOR
MEMORY
T
CELLS
.
187
MODULATION
OF
CD26
.
190
ASSOCIATION
OF
INTERLEUKIN-2
PRODUCTION
WITH
THE
EXPRESSION
OF
CD26
ON
HUMAN
T
LYMPHOCYTES
.
192
DIFFERENTIAL
HELPER
ACTIVITY
OF
CD4
+
/CD26
+
AND
CD4
+
/CD26~
T
LYMPHOCYTES
.
193
CORRELATION
OF
CD26
EXPRESSION
WITH
TH
1
-LIKE
REACTIONS
IN
GRANULOMATOUS
DISEASES
.
195
INDEX
.
201 |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV010491450 |
| illustrated | Illustrated |
| indexdate | 2024-08-23T00:50:57Z |
| institution | BVB |
| isbn | 3540601996 1570592942 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-006990609 |
| oclc_num | 488965875 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 202 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Springer [u.a.] |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spelling | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response Bernhard Fleischer New York [u.a.] Springer [u.a.] 1995 202 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Antigens, CD26 - immunology Antigens, CD26 - metabolism CD26 antigen Immunreaktion (DE-588)4133841-8 gnd rswk-swf Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Dipeptidylpeptidase IV (DE-588)4346023-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Dipeptidylpeptidase IV (DE-588)4346023-9 s Immunreaktion (DE-588)4133841-8 s DE-604 Stoffwechsel (DE-588)4057699-1 s Fleischer, Bernhard 1950- Sonstige (DE-588)139812393 oth DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006990609&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response Antigens, CD26 - immunology Antigens, CD26 - metabolism CD26 antigen Immunreaktion (DE-588)4133841-8 gnd Stoffwechsel (DE-588)4057699-1 gnd Dipeptidylpeptidase IV (DE-588)4346023-9 gnd |
| subject_GND | (DE-588)4133841-8 (DE-588)4057699-1 (DE-588)4346023-9 (DE-588)4143413-4 |
| title | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response |
| title_auth | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response |
| title_exact_search | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response |
| title_full | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response Bernhard Fleischer |
| title_fullStr | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response Bernhard Fleischer |
| title_full_unstemmed | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response Bernhard Fleischer |
| title_short | Dipeptidyl peptidase IV (CD26) in metabolism and the immune response |
| title_sort | dipeptidyl peptidase iv cd26 in metabolism and the immune response |
| topic | Antigens, CD26 - immunology Antigens, CD26 - metabolism CD26 antigen Immunreaktion (DE-588)4133841-8 gnd Stoffwechsel (DE-588)4057699-1 gnd Dipeptidylpeptidase IV (DE-588)4346023-9 gnd |
| topic_facet | Antigens, CD26 - immunology Antigens, CD26 - metabolism CD26 antigen Immunreaktion Stoffwechsel Dipeptidylpeptidase IV Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006990609&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT fleischerbernhard dipeptidylpeptidaseivcd26inmetabolismandtheimmuneresponse |