Verfügbarkeit: Enzyme engineering

Enzyme engineering: 12

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Format:	Tagungsbericht Buch
Sprache:	English
Veröffentlicht:	New York, NY 1995
Schriftenreihe:	New York Academy of Sciences: Annals of the New York Academy of Sciences 750
Schlagworte:	BIOTEHNOLOGIJA - kongresi ENCIMI - kongresi BIOTECHNOLOGY > congresses ENZYMES > congresses Konferenzschrift
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	XIII, 506 S. Ill., zahlr. graph. Darst.
ISBN:	0897669274 0897669282

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adam_text	ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Volume 750 March 31, 1995 ENZYME ENGINEERING XIIй Editors and Conference Organizers Marie-Dominique Legoy and Daniel Thomas Sponsor Engineering Foundation CONTENTS Introduction. By Daniel Thomas ........................................................................ xiii Part I. Mechanisms: Properties and Functions Reaction Mechanism for the Conversion of 5-Monosubstituted Hydantoins to Enantiomerically Pure L-Amino Acids. By Dirk Völkel and Fritz Wagner ................................................................................................ 1 Random Mutagenesis of the Substrate-binding Site of a Serine Protease: A New Library of a-Lytic Protease Si Mutants. By Lloyd D. Graham, Kevin D. Haggett, Patricia J. Hayes, Paul A. Schober, Philip A. Jennings, and Robert G. Whittaker ........................................................ 10 Regeneration of NAD by Conjugated Mannitol Dehydrogenase and Glucose Dehydrogenase Systems. By Gao Xiang Li and Yl Min He ........................ 15 The Design, Synthesis, and Activity of a Ribozyme That Specially Cleaves Rat 28S rRNA. By Jin Zhang, Changsheng Tian, and Hong Ying Zhang .............................................................................................................. 18 A Study of Dipeptide Synthesis Catalyzed by Protease in Organic Solvent. By Xue-Zhong Zhang, Songmin Chen, Xu Wang, Xiaoxia Wu, Zhongli Huang, and Baoqi Liu .................................................................. 24 A Multifunctional Flow-injection Biosensor for the Simultaneous Determination of Ammonia, Creatinine, and Urea. By Chang-Sheng Rui, Hiroaki I.-Ogawa, Kenji Sonomoto, and Yasuhiko Като ............ 30 З -Ketoacyl CoA Thiolases of a Yeast, Candida tropicalis: Properties and Functions. By Atsuo Tanaka, Tatsuo Kurihara, Naoki Kanayama, Haruyuki Atomi, and Mitsuyoshi Ueda ................................................. 39 Kinetic and Structural Observations of a Nonheme Iron Enzyme: Contribution of Conformational Changes to the Modification of Lipoxygenase Catalysis. By С Lambert, C. Pourplanche, M. Berjot, J. Marx, A. J. P. Alix, and V. Larreta-Garde ......................................... 44 Aspergillus ficuum Phytase Active Site: Involvement of Arg and Trp Residues. By Abul H. J. Ullah and H. Charles Dischinger Jr .............................. 51 Determination of the Intrinsic Michaelis Constant of Immobilized Heparinase. By Robert Lortie and Richard Broughton ...................... 58 The papers in this volume were presented at a conference entitled Enzyme Engineering XII, held on September 19-24, 1993, in Deauville, France. The conference was sponsored by the Engineering Foundation and by the American Institute of Chemical Engineers. Controlling Susceptibility against Protease Digestion. By Hiroshi іілма and ^ Keiichi Morimoto ........................................................................................ Raman Spectroscopie Study of the Effect of Polyethylene Glycol on the Dynamics of Water: Application to Thermal Denaturation of Enzymes. By Didier Combes, Isabelle Auzanneau, and Antoine Zwick............. oo A New Thermostable Chitinase from Themoactinomyces Species 1-1052: Application to the Controlled Depolymerization of Chitosan Polymers. By B. Brodel, J. P. Touzel, P. Debeire, F. Paul, P. MONSAN, and B.GYSIN ........................................................................................................... Regulation of Lactate Dehydrogenase Activity by Synthetic Polycations. By Lin Ma, Zeng-ji Li, Yu-Hua Cheng, and Jia-Cong Shen ........................ 75 Part П. Nanotechnology: Protein Modifications Micellar Enzymology for Enzyme Engineering: Ideas and Realization. By Andrey V. Levashov and Natalia Klyachko ......................................... 80 Structural Effect of Reversed Micelles of AOT over a Recombinant Cutinase from Fusarium solani pm: A Steady State Fluorescence Study. By E. P. Melo, S. M. B. Costa, and J. M. S. Cabral................................................ 85 Permanent Enzyme Microencapsulation in Reverse Micellar Media. By L. Robledo, V. Vilas, and C. Otero .......................................................... 89 Baroenzymology in Reversed Micelles. By Vadim V. Mozhaev, Nicole Вес, and Claude Balny ................................................................................ 94 Stability and Activity of Acid Phosphatase in Reverse Micelles. By M. Cantarella, D. Cifoni, N. Spreti, F. Alfani, R. Germani, and G. Savelli ................................................................................................ 97 Micromachining Technology and Biosensors. By Isao Karube, Kazunori Ikebukuro, Yuji Murakami, and Kenji Yokoyama ................................. 101 A Novel Electropolymerized Sensing Layer for Biosensors Involving Entrapped Enzyme-phospholipid Vesicles. By B. LECA, R. M. MORELIS, and P. R. Coulet ............................................................................................ 109 Reconstitution of a Functional Electron Transfer in a Biomimetic Structure, Including an Electrode Interface, Phospholipid and Ubiquinone Molecules, and a Membrane Enzyme. By Elisabeth Torchut, Christian Bourdillon, and Jean-Marc Laval ....................................... 112 In Vitro Glycosylation of Enzymes: Modification of Activity and Stability. By Isabelle Meynial, María Asunción Longo, and Didier Combes ........ 116 Optimization of RNase A Artificial Hydrophobization in AOT Reversed Micelles. By Stephane Robert, Dominique Domurado, Daniel Thomas, and Joel Chopineau ................................................. 121 Chemical and Enzymatic Glycosylation of Enzymes: Modification of Their Properties. By María Asunción Longo, Isabelle Meynial, and Didier Combes ............................................................... ,„5 General Strategies in the Stabilization of Enzymes by Structural Modification. By R. Venkatesh, Sudha Arun, N. Rajalakshmi Lauta Subramanian, V. Meenakshi, K. Venugopalan, and p V aUNDARAM .................. „„„ ............................................................................................. 130 Alteration of Specificity in L-Aspartase in the Presence of Alcohol. By Lin Ma, Bai-Xu Yan, Hai-Lin Zhao, Wei-Hua Liu, De-Lin You, and Yu-Hua Cheng ............................................................................................... 134 Enzymatic Polymerization of ^-Phenylphenol in Aqueous Micelles. By Wei-Hua Liu, J. D. Wang, Lin Ma, X. H. Liu, X. D. Sun, Yu-Hua Cheng, and T. J. Li ........................................................................................ 138 In Vitro Protein Biosynthesis Using Ribosome and Foreign mRNA: An Approach to Construct a Protein Biosynthesizer. By Tsuneo Yamane, Yasuaki Kawarasaki, and Hideo Nakano ............................................... 146 Part III. Metabolic Engineering and Gene Fusion Strategy of the Artificial Evolution of an Enzyme. By Savitr Trakulnaleamsai, Masako Yoshikawa, Tetsuya Yomo, and Itaru Urabe .............................................................................................................. 158 Stereoselective Microbial Reduction of 2-Keto-3-(A/-Benzoylamino)-3-Phenyl Propionic Acid Ethyl Ester: Synthesis of Taxol Side-chain Synthon. By Ramesh N. Patel, Amit Banerjee, Jeffrey M. Howell, Clyde G. McNamee, David Brzozowski, Venkat Nanduri, John K. Thottathil, and Laszlo J. Szarka ............................................................. 166 Time Course of Glutaminę in a Culture Medium during High-density Culture of Mouse C127 Transformants. By Kentaro Yoda, Toshio Tsuchida, and Hiroshi Takasugi .................................................................................. 175 Studies on the Engineering of Human Lysozyme. By Shi-Jun Qian, Ying Yu, Kai-Rong Tian, Qing-Hua Jiao, Jun Ye, and Guang-Zhen Meng................................................................................ 180 Optimal Reaction Conditions for the Enzymatic Synthesis of Optically Active D-p-Hydroxyphenylglycine from 5-substituted Hydantoin Using D-Hydantoinase and iV-Carbamoylase. By Geun-Joong Kim and Hak-SungKim ................................................................................................ 185 Part IV. Lipolytic Enzymes Relationships between Structures and Kinetic Properties of Pancreatic Lipases. By R. Verger, F. Ferrato, F. Carrière, C. Cudrey, N. Rugani, Y. Gargouri, A. Hjorth, H. Wöldike, E. Boel, L. Тнім, D. M. Lawson, G. G. Dodson, H. van Tilbeurgh, M. P. Egloff, and С Cambillau .................................................................................................. 190 Structural and Functional Aspects of an Industrial Lipase. By M. R. Egmond, W. P. Antheunisse, С. M. van Bemmel, P. Ravestein, and L. G. J. Frenken ............................................................................................. 195 Lipase Activity as a Function of Interfacial Tension Using the Rising Drop Method on a New Oil Drop Tensiometer. By Claus Ladefoged, Alain Cagna, and Erik Gormsen ........................................................................... 202 A New Method for Estimating the Selectivity of Lipases for Fatty Acids and Fatty Alcohols in Organic Solvents. By Shi-De Liu, Shu-Gui Cao, Zhong-Tian Ding, Ling-Feng Sun, Nian-Xiang Zhang, Qi-Zhi Liang, Hong-Hu Liu, and Hong Yang ....................................................... 209 Lipase-catalyzed Kinetic Resolution of 3-Hydroxy Esters: Optimization, Batch, and Continuous Reactions. By U. Bornscheuer, A. HERAR, A. Capewell, V. Wendel, L. Kreye, T. Scheper, E. Voß, К. Wünsche, and H. H. Meyer ..................................................................... 215 Studies on a New Type of Immobilized Lipase Fitting in Organic Solvents. By Shu-Gui Cao, Shi-De Liu, Lin Ma, Nian-Xiang Zhang, Zhong-Tian Ding, Ling-Feng Sun, Qi-Zhi Liang, Hong-Hu Liu, and Hong Yang.. 222 Selective Esterification of Racemic Ibuprofen. By F. Ergan, M. Trani, and R. Lortie ......................................................................................................... 228 Enzymatic Hydrolysis of Castor Oil for Valuable Fatty Acid Production. By Tsuyosi Yamakido, Kazunori Kiyoga, Yoshio Matsumoto, Hiroaki I.-Ogawa, Kenji Sonomoto, and Yasuhiko Kato .................... 232 Studies on Enzyme Reuse and Product Recovery in Lipase-catalyzed Reactions in Microemulsions. By H. Stamatis, A. Xenakis, and F. N. Kolisis ............................................................................................................. 237 Enzymatic Synthesis of Oleins in Organic Media. By Eitel PASTOR, Antonio Ballesteros, Francisco J. Plou, and Cristina Otero.......... 242 Poly(methyl acrylate-methyl methacrylate-divinyl benzene) Beads for Immobilization of Lipase. By W. M. Z. Wan Yunus, A. B. Salleh, M. Basri, С N. A. Razak, and K. Ampon ................................................... 246 Optical Resolution of (R, S) 2-Octanol with Lipases in Organic Solvent. By Hong Yang, Shu-Gui Cao, Si-Ping Han, Ying Feng, Zong-Tian Ding, Ling-Feng Sun, and Yu-Hua Cheng ............................................... 250 Part V. Abzymes: Recognition and Affinity Mechanisms DNA-hydrolyzing Autoantibodies in Autoimmune Pathologies. By DMITRY V. Schourov, Gennady V. Gololobov, Oksana I. Makarevich, Rana P. Yadav, Elena A. Chernova, Georgy A. Nevinsky, Tatyana B. Prokaeva, Zemphira S. Alekberova, and Alexander G. Gabibov ...................................................................................................... 255 Antiidiotypic Antibodies as Functional Internal Images of Enzyme-active Sites. By Alain Friboulet, Ladan Izadyar, Bérangère Avalle, Alberto Roseto, and Daniel Thomas ...................................................... 265 Study of the Abzyme with Peroxidase Catalytic Activity. By Y. Feng, Z. Liu, G. Gao, S. J. Gao, X. Y. Liu, and T. S. Yang.............................................. 271 A New Strategy for Generating Selenium-containing Abzyme: Chemical Mutation of Monoclonal Antibodies with Substrate-binding Sites. By Gui-Min Luo, Lan Ding, Zhen-Qi Zhu, Gui Gao, Qi-An Sun, Zhi Liu, Tong-Shu Yang, and Jia-Cong Shen ................................................. 277 Complementary Approach for the Determination of Histidine in the Metal-binding Site of an Anti-DTPA-Indium Monoclonal Antibody. By Valérie Boden, Carole Colin, Jacques Barbet, Jean Marc Le DoussAL, and Mookambeswaran Vijayalakshmi ................................... 284 Chelate-mediated Immobilization of Proteins by way of Extremely Stable Complexes. By D. Kirstein and B. Micheel ................................................ 288 Protein Disulfide Isomerase Reaction Kinetics in Endoplasmic Reticulum for Monoclonal Antibody Refolding and Assembly. By SUN Ho PARK and Dewey D. Y. Ryu ........................................................................................... 291 Part VI. Sugars and Glycoproteins N-Acetylneuraminic Acid: From a Rare Chemical from Natural Sources to a Multikilogram Enzymatic Synthesis for Industrial Application. By Udo Kragl, Matthias Kittelmann, Oreste Ghisalba, and Christian Wandrey ......................................................................................................... 300 Production of Alkyl ß-D-Xylosides with the Trichoderma reesei ß-Xylosidase. By Philippe Drouet, Ми Zhang, and Marie-Dominique Legoy ........... 306 Equilibrium Study of Alkyl-ß-D-Glucoside Synthesis from Glucose and Alcohol by ß-Glucosidase. By Yukitaka Kimura, Chaiya Panintrarux, Shuji Adachi, and Ryuichi Matsuno .............................. 312 Enzymatic Production of Glucooligosaccharides Containing ot-(1^^2) Osidic Bonds: Potential Application in Nutrition. By M. Quirasco, A. Lopez- Munguia, V. Pelenc, M. Remaud, F. Paul, and P. Monsan ................... 317 Enzymatic Synthesis of Low-calorie Sugar Substitutes: Cellobiofructose and Gentiobiofructose. By Jacques Biton, Jean-Marc Michel, Dominique Le Beller, Vincent Pelenc, François Paul, Pierre F. Monsan, and Gérard Gellf............................................................................................... 321 Transglucosylatipn of a Fungal ct-Glucosidase: The Enzyme Properties and Correlation of Isomaltooligosaccharide Production. By Kow-Jen Duan, Dey-Chyi Sheu, and Chi-Tsai Lin ............................................................... 325 Application of Sucrose Synthase from Rice Grains for the Synthesis of Carbohydrates. By Lothar Elling, Marita Grothus, Astrid Zervosen, and Maria-Regina Kula .......................................................... 329 Enzymatic Synthesis of Partially Acylated Sucroses. By F. J. Plou, M. A. Cruces, M. Bernabé, M. Martin-Lomas, J. L. Parra, and A. Ballesteros .............................................................................................. 332 Enzymes from Zymomonas mobilis and Their Application to Glucose Determination. By Kosuké Tomita and Kumiko Nomura ........................ 338 Glycosylation-induced Conformational Difference between Glycoforms of Glucoamylase. By Shuzheng Zhang, Suguo Ge, Shoujun Yang, Zizheng Yan, Haini Yu, and Weitong Wang ........................................... 344 Part VII. Applications Design of Novel Biocatalysts by Bioimprinting during Unfolding-Refolding of Fully Dispersed Covalently Immobilized Enzymes. By Gloria Soler, Rosa M. Blanco, Roberto Fernandez-Lafuente, Cristina M. RosELL, and José M. Guisan ........................................................................ 349 New Developments in the Application of Enzymes to Synthesis Reactions: Peptides and Oligosaccharides. By Pierre Monsan, François Paul, and Daniel Auriol ........................................................................................ 357 Industrial Application of Immobilized Biocatalysts in Japan. By Tetsuya Tosa and Takeji Shibatani .......................................................................... 364 Novel Industrial Enzyme Applications. By Sven Pedersen, Niels Krebs Lange, and Anne Mette Nissen.................................................................. 376 Synthesis of Chloroformâtes for Enzyme Immobilization. By William H. Scouten and Milan Dvorak ....................................................................... 391 Industrial Utilization of a Hollow-fiber Membrane Reactor for the Controlled Lipolysis of Butterfat. By F. Xavier Malcata and Charles G.HillJr ........................................................................................................ 401 The Enzymatic Reaction-Fractionation Process in Supercritical Carbon Dioxide. By Alain Marty, Sophie Manon, Dong Pyo Ju, Didier Combes, and Jean-Stéphane Condoret .................................................... 408 Production of Fibrin Polymerization Inhibitor from Collagen by Some Proteases. By Isao Nonaka, Hideoki Tanaka, and Ѕиѕими Maruyama ...................................................................................................... 412 Production of L-Amino Acids by Applying D-Amino Acid Oxidases. By LUTZ Fischer, Roy Hörner, and Fritz Wagner ............................................... 415 Preparation of (R)- and (5)-Propylene Glycol with Baker s Yeast. By Tadashi Kometani and Ryuichi Matsuno ................................................ 421 Resolution of Racemic Mixtures through Stereospecific Kinetically Controlled Synthesis Catalyzed by Penicillin G Acylase Derivatives. By Cristina M. Rosell, Roberto Fernandez-Lafuente, and José M. Guisan ............................................................................................................. 425 Production of Bioactive Peptides from Corn Endosperm Proteins by Some Proteases. By Shinsuke Miyoshi, Toshiyuki Kaneko, Hiromi Ishikawa, Hideoki Tanaka, and Ѕиѕими Maruyama ............................. 429 Bioremediation Using an Immobilized Cell Generator. By D. F. Day, M. L. Marceau-Day, and B. M. Day ..................................................................... 432 An Integrated Bioreactor System for Biologically Active Peptides from Isolated Soybean Protein. By Kenji Sonomoto and Yasunori Okamoto ......................................................................................................... 435 Screening of Concanavalin А -Bead Cellulose Conjugates by an Enzyme Thermistor Using Immobilized Invertase as the Reporter Catalyst. By Peter Dočolomanský, Peter Gemeiner, Danica Mislovičová, Vladimír Štefuca, and Bengt Danielsson.............................................. 441 Enhanced Subtilisin Production with Spore Mutants of Bacillus subtilis and Their Characterization. By M. К. Он, S. H. Park, and B. G. Кім ............... 444 Peptic Hemoglobin Hydrolysis in an Ultrafiltration Reactor at Pilot Plant Scale Generates Opioid Peptides. By Qiuyu Zhao, Jean-Marie Piot, Frederic Sannier, and Didier Guillochon ............................................ 452 Photosensitizing Activity of Porphyrinic Peptide Hydrolysates Derived from Bovine Hemoglobin. By N. Cempel, J. M. Piot, J. M. Aubry, T. Patrice, M. T. Foultier, and D. Guillochon ...................................... 459 Evaluation of Bacteriocin Activity Produced in Milk by Lactococcus lactis, Subspecies lactis, Immobilized in Barium Alginate Beads. By G. Pasini, A. Crapisi, A. Lante, A. Curioni, A. Zamorani, and P. Spettoli .......... 465 Comparative Studies of Plant and Fungal Peroxidases. By Alexey M. Egorov, Irina A. Reshetnikova, Victoria A. Fechina, and Irina G. Gazaryan....................................................................................................... 469 Large-scale Production of Chiral Alcohols with High Enantiomeric Excess through Yeast-mediated Asymmetric Reduction of Prochiral Ketones: Fed-batch Type Aerobic Bioreactor Using Ethanol as an Energy Source for NADPH Regeneration. By Ryuichi Matsuno, Shuji Adachi, and Tadashi Kometani ........................................................................................ 473 Purification and Properties of Uricase from Candida Sp. and Its Application in Uric Acid Analysis in Serum. By Jianguo Liu, Gao Xiang Li, Hong Liu, and Xiukai Zhou .................................................................................... 477 Two New Countercurrent Adsorptive Enzyme Reactors: Operational Conditions for Deacylation of Penicillin G. By L. A. M. van der Wielen, P. J. Diepen, A. J. J. Straathof, and К. Сн. A. M. Luyben ...................... 482 Preliminary Investigation for the Continuous Enzymatic Production of 7-Aminocephalosporanic Acid. By F. Alfani, N. Cutarella, A. Gallifuoco, M. Cantarella, P. Golini, G. Franzosi, and D. Bianchi ....................................................................................................... 491 Experimentally Targeted Thrombolytic Therapy: Application of Modified Thrombin Conjugated with Uroicinase. By Alexander V. Maksimenko, Artem D. Petrov, Elena G. Tischenko, and Mikhail D. Smirnov ...... 496 Index of Contributors ............................................................................................ 503 The New York Academy of Sciences believes it has a responsibility to provide an open forum for discussion of scientific questions. The positions taken by the participants in the reported conferences are their own and not necessarily those of the Academy. The Academy has no intent to influence legislation by providing such forums.
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physical	XIII, 506 S. Ill., zahlr. graph. Darst.
publishDate	1995
publishDateSearch	1995
publishDateSort	1995
record_format	marc
series	New York Academy of Sciences: Annals of the New York Academy of Sciences
series2	New York Academy of Sciences: Annals of the New York Academy of Sciences Annals of the New York Academy of Sciences
spelling	Enzyme engineering 12 ed. by A. I. Laskin ... 1995 New York, NY XIII, 506 S. Ill., zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier New York Academy of Sciences: Annals of the New York Academy of Sciences 750 Annals of the New York Academy of Sciences ... BIOTEHNOLOGIJA - kongresi ENCIMI - kongresi BIOTECHNOLOGY congresses ENZYMES congresses (DE-588)1071861417 Konferenzschrift gnd-content Laskin, Allen I. Sonstige oth Dordick, Jonathan S. Sonstige oth International Enzyme Engineering Conference Sonstige (DE-588)131227-3 oth (DE-604)BV000253031 12 New York Academy of Sciences: Annals of the New York Academy of Sciences 750 (DE-604)BV002532608 750 Digitalisierung TU Muenchen application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006858186&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Enzyme engineering New York Academy of Sciences: Annals of the New York Academy of Sciences BIOTEHNOLOGIJA - kongresi ENCIMI - kongresi BIOTECHNOLOGY congresses ENZYMES congresses
subject_GND	(DE-588)1071861417
title	Enzyme engineering
title_auth	Enzyme engineering
title_exact_search	Enzyme engineering
title_full	Enzyme engineering 12 ed. by A. I. Laskin ...
title_fullStr	Enzyme engineering 12 ed. by A. I. Laskin ...
title_full_unstemmed	Enzyme engineering 12 ed. by A. I. Laskin ...
title_short	Enzyme engineering
title_sort	enzyme engineering
topic	BIOTEHNOLOGIJA - kongresi ENCIMI - kongresi BIOTECHNOLOGY congresses ENZYMES congresses
topic_facet	BIOTEHNOLOGIJA - kongresi ENCIMI - kongresi BIOTECHNOLOGY congresses ENZYMES congresses Konferenzschrift
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006858186&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
volume_link	(DE-604)BV000253031 (DE-604)BV002532608
work_keys_str_mv	AT laskinalleni enzymeengineering12 AT dordickjonathans enzymeengineering12 AT internationalenzymeengineeringconference enzymeengineering12

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