Holdings: Cannabinoid receptors

Cannabinoid receptors:

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Bibliographic Details
Format:	Book
Language:	Undetermined
Published:	London u.a. Acad. Press 1995
Series:	Neuroscience perspectives
Subjects:	Cannabinoide Rezeptor
Online Access:	Inhaltsverzeichnis
Physical Description:	XIV, 264 S. graph. Darst.
ISBN:	0125514603

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MARC


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Record in the Search Index

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adam_text	CANNABINOID RECEPTORS EDITED BY R. G. PERTWEE DEPARTMENT OF BIOMEDICAL SCIENCES MARISCHAL COLLEGE, UNIVERSITY OF ABERDEEN ABERDEEN, SCOTLAND ACADEMIC PRESS HARCOURT BRACE & COMPANY, PUBLISHERS LONDON SAN DIEGO NEW YORK BOSTON SYDNEY TOKYO TORONTO CONTENTS CONTRIBUTORS IX SERIES PREFACE XI PREFACE XIII 1 PHARMACOLOGICAL, PHYSIOLOGICAL AND CLINICAL IMPLICATIONS OF THE DISCOVERY OF CANNABINOID RECEPTORS: AN OVERVIEW 1 R.G. PERTWEE 1.1 INTRODUCTION 2 1.2 PHARMACOLOGICAL IMPLICATIONS OF THE DISCOVERY OF THE ANANDAMIDE SYSTEM 10 1.3 PHYSIOLOGICAL IMPLICATIONS OF THE DISCOVERY OF THE ANANDAMIDE SYSTEM 18 1.4 CLINICAL IMPLICATIONS OF THE DISCOVERY OF THE ANANDAMIDE SYSTEM 21 REFERENCES 29 2 STRUCTURAL REQUIREMENTS FOR CANNABINOID RECEPTOR PROBES 35 BILLY R. MARTIN, BRIAN F. THOMAS AND RAJ K. RAZDAN 2.1 INTRODUCTION 36 2.2 CRITICAL DESCRIPTION OF IN VIVO AND IN VITRO ASSAY SYSTEMS 36 2.3 PHARMACOLOGICAL ACTIVITY IN LABORATORY ANIMALS 54 2.4 PHARMACOLOGICAL ACTIVITY IN HUMANS 64 2.5 MOLECULAR MODELLING OF THE CANNABINOID PHARMACOPHORE 65 2.6 EVIDENCE FOR AND AGAINST RECEPTOR SUBTYPES 70 2.7 STRATEGIES FOR DEVELOPING ANTAGONISTS 72 2.8 PROMISING LEADS 76 2.9 SUMMARY 77 ACKNOWLEDGEMENTS 79 REFERENCES 79 3 THE ROLE OF CELL MEMBRANES IN CANNABINOID ACTIVITY 87 ALEXANDROS MAKRIYANNIS 3.1 INTRODUCTION 88 3.2 MEMBRANE-BASED CANNABINOID ACTIVITY 89 CONTENTS 3.3 CONCLUSION 109 REFERENCES 111 MOLECULAR BIOLOGY OF THE CANNABINOID RECEPTOR 117 LA. MATSUDA AND T.I. BANNER 4.1 INTRODUCTION 117 4.2 THE CLONED CANNABINOID RECEPTOR 119 4.3 THE RECEPTOR GENE AND ITS EXPRESSION 129 4.4 UNRESOLVED ISSUES AND RESEARCH IMPLICATIONS 136 4.5 SUMMARY 139 REFERENCES 140 LOCALIZATION OF CANNABINOID RECEPTORS IN BRAIN AND PERIPHERY 145 MILES HERKENHAM 5.1 INTRODUCTION 145 5.2 LOCALIZATION OF CANNABINOID BINDING SITES 147 5.3 LOCALIZATION OF CANNABINOID RECEPTOR MRNA 156 5.4 CONCLUSIONS 159 REFERENCES 161 CANNABINOID COMPOUNDS AND SIGNAL TRANSDUCTION MECHANISMS 167 ALLYN C. HOWLETT * 6.1 CELLULAR MECHANISMS FOR CANNABINOID COMPOUNDS 168 6.2 SIGNAL TRANSDUCTION VIA THE CB! RECEPTOR AS A G PROTEIN-COUPLED RECEPTOR 174 6.3 PHOSPHOLIPASE C 189 6.4 CANNABINOID COMPOUNDS AND EICOSANOIDS 190 6.5 PROTEIN KINASE C 195 6.6 IMPLICATIONS AND FUTURE DIRECTIONS 196 REFERENCES 197 FUNCTIONAL SIGNIFICANCE OF CANNABINOID RECEPTORS IN BRAIN 205 SAM A. DEADWYLER, ROBERT E. HAMPSON AND STEVEN R. CHILDERS 7.1 INTRODUCTION 206 7.2 CELLULAR ACTIONS OF CANNABINOIDS 206 7.3 CANNABINOID EFFECTS ON SYNAPTIC MECHANISMS 214 7.4 ENDOGENOUS CANNABINOID SUBSTANCES IN BRAIN 214 7.5 CANNABINOID ACTIONS IN CEREBELLUM 216 7.6 RECEPTOR CONVERGENCE IN CEREBELLAR GRANULE CELLS 218 7.7 FUNCTIONAL CONSEQUENCES OF CANNABINOID RECEPTOR ACTIVATION 220 VI CONTENTS 7.8 PROMISING LEADS - POTENTIAL ROLE OF CANNABINOID RECEPTORS IN HIPPOCAMPUS 222 7.9 SUMMARY 226 ACKNOWLEDGEMENTS 226 REFERENCES 227 THE UNPAVED ROAD TO THE ENDOGENOUS BRAIN CANNABINOID LIGANDS, THE ANANDAMIDES 223 R. MECHOULAM AND E. FRIDE 8.1 8.2 8.3 8.4 8.5 8.6 8.7 INTRODUCTION TECHNICAL AND CONCEPTUAL PROBLEMS MYELIN BASIC PROTEIN - A POTENTIAL CANNABINOID LIGAND STEREOSELECTIVITY OF CANNABIMIMETIC ACTION VARIOUS APPROACHES TOWARDS DIE IDENTIFICATION OF ENDOGENOUS CANNABINOIDS ANANDAMIDE CONCLUSION ACKNOWLEDGEMENTS REFERENCES 233 234 236 237 241 242 254 255 255 INDEX 259 VII
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ctrlnum	(OCoLC)832427296 (DE-599)BVBBV010187322
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illustrated	Illustrated
indexdate	2025-03-19T17:00:22Z
institution	BVB
isbn	0125514603
language	Undetermined
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owner	DE-355 DE-BY-UBR DE-19 DE-BY-UBM
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physical	XIV, 264 S. graph. Darst.
publishDate	1995
publishDateSearch	1995
publishDateSort	1995
publisher	Acad. Press
record_format	marc
series2	Neuroscience perspectives
spelling	Cannabinoid receptors ed. by R. G. Pertwee London u.a. Acad. Press 1995 XIV, 264 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neuroscience perspectives Cannabinoide (DE-588)4069839-7 gnd rswk-swf Rezeptor (DE-588)4049722-7 gnd rswk-swf Rezeptor (DE-588)4049722-7 s Cannabinoide (DE-588)4069839-7 s DE-604 Pertwee, Roger Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006767962&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Cannabinoid receptors Cannabinoide (DE-588)4069839-7 gnd Rezeptor (DE-588)4049722-7 gnd
subject_GND	(DE-588)4069839-7 (DE-588)4049722-7
title	Cannabinoid receptors
title_auth	Cannabinoid receptors
title_exact_search	Cannabinoid receptors
title_full	Cannabinoid receptors ed. by R. G. Pertwee
title_fullStr	Cannabinoid receptors ed. by R. G. Pertwee
title_full_unstemmed	Cannabinoid receptors ed. by R. G. Pertwee
title_short	Cannabinoid receptors
title_sort	cannabinoid receptors
topic	Cannabinoide (DE-588)4069839-7 gnd Rezeptor (DE-588)4049722-7 gnd
topic_facet	Cannabinoide Rezeptor
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006767962&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT pertweeroger cannabinoidreceptors

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