Anesthesia and cardiovascular disease:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego [u.a.]
Acad. Press
1994
|
| Schriftenreihe: | Advances in pharmacology
31 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Einzelaufnahme eines Zeitschr.-Bd. |
| Beschreibung: | XXX, 666 S. Ill., graph Darst. |
| ISBN: | 0120329328 |
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| adam_text | 733-3 F 8 ADVANCES IN : PHARMACOLOGY VOLUME 31 ANESTHESIA AND
CARDIOVASCULAR DISEASE EDITED BY ZELJKO J. BOSNJAK DEPARTMENTS OF
ANESTHESIOLOGY AND PHYSIOLOGY THE MEDICAL COLLEGE OF WISCONSIN
MILWAUKEE, WISCONSIN JOHN P. KAMPINE DEPARTMENTS OF ANESTHESIOLOGY AND
PHYSIOLOGY THE MEDICAL COLLEGE OF WISCONSIN MILWAUKEE, WISCONSIN
ACADEMIC PRESS SAN DIEGO NEW YORK BOSTON LONDON SYDNEY TOKYO TORONTO
CONTENTS CONTRIBUTORS XXI PREFACE XXIX PART I CARDIAC MUSCLE REGULATION
OF THE CALCIUM SLOW CHANNELS OF HEART BY CYCLIC NUCLEOTIDES AND EFFECTS
OF ISCHEMIA NICHOLAS SPERELAKIS I. INTRODUCTION 1 II. TYPES OF CALCIUM
CHANNELS 2 III. CYCLIC AMP STIMULATION OF SLOW CALCIUM CHANNELS 6 IV.
PHOSPHORYLATION HYPOTHESIS 7 V. PROTEIN KINASE A STIMULATION 9 VI.
CYCLIC GMP INHIBITION OF SLOW CALCIUM CURRENT 9 VII. PROTEIN KINASE G
INHIBITION 14 VIII. INHIBITION BY MUSCARINIC AGONISTS 16 IX. PROTEIN
KINASE C AND CALMODULIN PROTEIN KINASE 18 X. COMPARISON WITH VASCULAR
SMOOTH MUSCLE AND SKELETAL MUSCLE 18 XI. DIRECT STIMULATION OF SLOW
CALCIUM CHANNELS BY G S PROTEINS AND /3-RECEPTORS 20 XII. SUMMARY 20
REFERENCES 21 FUNCTIONAL ADAPTATION TO MYOCARDIAL ISCHEMIA: INTERACTION
WITH VOLATILE ANESTHETICS IN CHRONICALLY INSTRUMENTED DOGS PATRICK F.
WOUTERS, HUGO VAN AKEN, MARC VAN DE VELDE, MARCO A. E. MARCUS, AND
WILLEM FLAMENG I. INTRODUCTION 25 II. CHRONIC INSTRUMENTATION AND
MONITORING 26 III. EFFECTS OF ISCHEMIC PRECONDITIONING ON FUNCTIONAL
RECOVERY FROM STUNNING IN CONSCIOUS DOGS 29 IV. DISCUSSION 31 REFERENCES
36 V1 CONTENTS EXCITATION*CONTRACTION UNCOUPLING AND VASODILATORS FOR
LONG-TERM COLD PRESERVATION OF ISOLATED HEARTS DAVID F. STOWE I.
INTRODUCTION 39 II. LONG-TERM CARDIAC PERFUSION 42 III. PRESERVATION OF
ISOLATED HEARTS 46 A. ATRIAL RATE, ATRIAL-VENTRICULAR CONDUCTION, AND
CARDIAC RHYTHM 46 B. LEFT VENTRICULAR PRESSURE AND CARDIAC EFFICIENCY 47
C. CORONARY FLOW AND OXYGEN EXTRACTION 49 D. RESPONSES TO VASODILATORS
51 IV. DISCUSSION 54 REFERENCES 59 TROPONIN T AS A MARKER OF
PERIOPERATIVE MYOCARDIAL CELL DAMAGE H. MACHLER, H. GOMBOTZ, K. SABIN,
AND H. METZLER I. INTRODUCTION 63 II. CARDIAC TROPONIN 64 III. TROPONIN
T IN CORONARY ARTERY BYPASS PATIENTS WITH UNSTABLE ANGINA 65 IV.
TROPONIN T VERSUS CONVENTIONAL MARKERS OF MYOCARDIAL CELL DAMAGE IN
PERIOPERATIVE SETTINGS 70 V. SUMMARY 71 REFERENCES 72 SILENT MYOCARDIAL
ISCHEMIA: PATHOPHYSIOLOGY AND PERIOPERATIVE MANAGEMENT ANDERS G. HEDMAN
I. INTRODUCTION 75 A. TYPE 1 SILENT MYOCARDIAL ISCHEMIA 75 B. TYPE II
SILENT MYOCARDIAL ISCHEMIA 76 C. TYPE III SILENT MYOCARDIAL ISHEMIA 76
II. PATHOPHYSIOLOGY OF SILENT MYOCARDIAL ISCHEMIA 76 A. GLOBAL
DEFICIENCY IN PAIN PERCEPTION 76 B. ANATOMIC CHANGES IN PAIN RECEPTORS
AND NERVES 77 C. QUANTITATIVE THEORY OF SILENT MYOCARDIAL ISCHEMIA 77
III. DETECTION OF SILENT MYOCARDIAL ISCHEMIA 79 CONTENTS VII IV. WHICH
LABORATORY METHODS SHOULD BE USED FOR SCREENING PURPOSES? 80 A. EXERCISE
STRESS TEST 80 B. THALLIUM-201 DIPYRIDAMOLE MYOCARDIAL IMAGING 81 C.
AMBULATORY LONG-TERM ELECTROCARDIOGRAPHIC MONITORING OF ST SEGMENT 81 V.
PERIOPERATIVE MEDICAL MANAGEMENT OF SILENT MYOCARDIAL ISCHEMIA 82 A.
NITRATES 84 B. A-ADRENERGIC BLOCKERS 84 C. /8-ADRENERGIC BLOCKERS 84 D.
CALCIUM ANTAGONISTS 84 E. SURGERY AND ANGIOPLASTY 85 VI. SUMMARY 85
REFERENCES 85 EFFECT OF HALOTHANE ON SARCOLEMMAL CALCIUM CHANNELS DURING
MYOCARDIAL ISCHEMIA AND REPERFUSION BENJAMIN DRENGER, YEHUDA GINOSAR,
AND YAACOV GOZAL I. INTRODUCTION 89 II. CANINE MODEL FOR MYOCARDIAL
ISCHEMIA AND REPERFUSION 90 III. ISOLATION OF SARCOLEMMA-ENRICHED
PREPARATION 92 IV. BINDING CAPACITY OF ISRADIPINE 92 V. SUMMARY 95
REFERENCES 95 MYOCARDIAL ISCHEMIC PRECONDITIONING DONNA M. VAN WINKLE,
GRACE L. CHIEN, AND RICHARD F. DAVIS I. INTRODUCTION 99 II. MYOCARDIAL
ISCHEMIA 100 III. EFFECTS ON INFARCT SIZE 103 IV. DISCUSSION 106
REFERENCES 107 EFFECTS OF HYPOXIA/REOXYGENATION ON INTRACELLULAR CALCIUM
ION HOMEOSTASIS IN VENTRICULAR MYOCYTES DURING HALOTHANE EXPOSURE PAUL
R. KNIGHT, MITCHELL D. SMITH, AND BRUCE A. DAVIDSON I. INTRODUCTION 109
II. INTRACELLULAR CALCIUM MEASUREMENTS 111 A. PREPARATION OF VENTRICULAR
MYOCYTES 111 B. MEASUREMENT OF INTRACELLULAR CALCIUM-ION CONCENTRATION
112 VLLL CONTENTS III. EFFECTS OF HYPOXIA, WITH OR WITHOUT HALOTHANE, ON
MYOCYTE MORPHOLOGY 113 IV. EFFECTS OF HYPOXIA, WITH OR WITHOUT
HALOTHANE, ON INTRACELLULAR CALCIUM 114 V. EFFECTS OF HYPOXIA, WITH OR
WITHOUT HALOTHANE, ON ELECTRICALLY INDUCED CALCIUM TRANSIENTS 116 VI.
EFFECTS OF HYPOXIA, WITH OR WITHOUT HALOTHANE, ON CAFFEINE-INDUCED
CALCIUM TRANSIENTS 117 VII. DISCUSSION 117 REFERENCES 122 MECHANICAL
CONSEQUENCES OF CALCIUM CHANNEL MODULATION DURING VOLATILE
ANESTHETIC-INDUCED LEFT VENTRICULAR SYSTOLIC AND DIASTOLIC DYSFUNCTION
PAUL S. PAGEL AND DAVID C. WARLTIER I. INTRODUCTION 125 II. MATERIALS
AND METHODS 127 A. NIFEDIPINE 127 B. BAY K 8644 128 C. CALCULATION OF
INDICES OF SYSTOLIC AND DIASTOLIC LEFT VENTRICULAR FUNCTION 129 D.
STATISTICS 130 III. EFFECTS OF ANESTHETICS AND CALCIUM CHANNEL
MODULATION 130 IV. DISCUSSION 135 REFERENCES 139 ANESTHETIC ACTIONS ON
CALCIUM UPTAKE AND CALCIUM- DEPENDENT ADENOSINE TRIPHOSPHATASE ACTIVITY
OF CARDIAC SARCOPLASMIC RETICULUM NING MIAO, MARTHA J. FRAZER, AND CARL
LYNCH III I. INTRODUCTION 145 II. SARCOPLASMIC RETICULUM 147 A.
PREPARATION OF CARDIAC SARCOPLASMIC RETICULUM 147 B. CALCIUM UPTAKE
MEASUREMENT 148 C. PHOSPHATE PRODUCTION MEASUREMENT 149 D. REAGENTS AND
ANESTHETIC ADMINISTRATION 149 III. CALCIUM UPTAKE AND ATPASE ACTIVITY
150 IV. DISCUSSION 156 A. CONTROL BEHAVIOR 157 B. ANESTHETIC EFFECTS 159
REFERENCES 162 CONTENTS IX INTERACTION OF ANESTHETICS AND CATECHOLAMINES
ON CONDUCTION IN THE CANINE HIS*PURKINJE SYSTEM LAWRENCE A. TURNER,
SANJA VODANOVIC, AND ZELJKO J. BOSNJAK I. INTRODUCTION 167 II.
CATECHOLAMINE-ANESTHETIC INTERACTION 168 III. SUMMARY 180 REFERENCES 181
ANESTHETICS, CATECHOLAMINES, AND OUABAIN ON AUTOMATICITY OF PRIMARY AND
SECONDARY PACEMAKERS JOHN L. ATLEE III, MARTIN N. VICENZI, HARVEY J.
WOEHLCK, AND ZELJKO J. BOSNJAK I. INTRODUCTION 185 II. ISOLATED AND
CHRONIC ATRIAL PREPARATIONS 186 A. CANINE RIGHT ATRIAL PREPARATION 187
B. CHRONICALLY INSTRUMENTED DOGS 188 III. ANESTHETIC INTERACTIONS WITH
OUABAIN AND CATECHOLAMINES 190 A. CANINE RIGHT ATRIAL PREPARATION 190 B.
CHRONICALLY INSTRUMENTED DOGS 193 IV. DISCUSSION 197 A. EXPERIMENTS IN
ISOLATED HEARTS 198 B. EXPERIMENTS IN INTACT HEARTS 200 V. CONCLUSIONS
203 VI. FUTURE DIRECTIONS 203 REFERENCES 203 THE ROLE OF L-TYPE
VOLTAGE-DEPENDENT CALCIUM CHANNELS IN ANESTHETIC DEPRESSION OF
CONTRACTILITY THOMAS J. J. BLANCK, D. L. LEE, S. YASUKOCHI, C. HOLLMANN,
AND J. ZHANG I. INTRODUCTION 207 II. ISOLATED HEART PREPARATION 210 III.
EFFECTS OF ANESTHETICS ON ISRADIPINE BINDING 211 IV. DISCUSSION 213
REFERENCES 214 CONTENTS EFFECTS OF INHIBITION OF TRANSSARCOLEMMAL
CALCIUM INFLUX ON CONTENT AND RELEASABILITY OF CALCIUM STORED IN
SARCOPLASMIC RETICULUM OF INTACT MYOCARDIUM HIROCHIKA KOMAI AND BEN F.
RUSY I. INTRODUCTION 215 II. ISOLATED PAPILLARY MUSCLE PREPARATION 216
III. CALCIUM INFLUX AND RELEASE 216 IV. DISCUSSION 220 REFERENCES 220
ARRHYTHMOGENIC EFFECT OF INHALATION ANESTHETICS: BIOCHEMICAL
HETEROGENEITY BETWEEN CONDUCTION AND CONTRACTILE SYSTEMS AND PROTEIN
UNFOLDING ISSAKU UEDA AND JANG-SHING CHIOU I. INTRODUCTION 223 II.
CYCLIC AMP AND THE CONDUCTION SYSTEM 224 III. MYOCARDIAL SENSITIZING
AGENTS AND PHOSPHODIESTERASE 225 IV. MODE OF ANESTHETIC-PROTEIN
INTERACTION 226 V. UNFOLDING OF PROTEINS 228 VI. SPECIFIC BINDING: LACK
OF DEFINITION 231 REFERENCES 232 PART II CORONARY CIRCULATION POTASSIUM
CHANNEL CURRENT AND CORONARY VASODILATATION BY VOLATILE ANESTHETICS
NEDILJKA BULJUBASIC, JURE MARIJIC, AND ZELJKO J. BOSNJAK I. INTRODUCTION
235 II. ISOLATED VESSEL RING EXPERIMENTS 236 III. PATCH CLAMP
EXPERIMENTS 238 IV. EFFECTS OF ANESTHETICS ON ISOLATED CORONARY VESSELS
239 V. EFFECTS OF ANESTHETICS ON WHOLE-CELL POTASSIUM CURRENT 241 VI.
EFFECTS OF ANESTHETICS ON SINGLE POTASSIUM CHANNEL CURRENT 243 VII.
DISCUSSION 248 REFERENCES 251 CONTENTS XI POTASSIUM CHANNEL OPENING AND
CORONARY VASODILATION BY HALOTHANE D. R. LARACH, H. G. SCHULER, K. A.
ZANGARI, AND R. L. MCCANN I. INTRODUCTION 253 II. ISOLATED CORONARY
VESSEL PREPARATION 254 III. EFFECTS OF ENDOTHELIN 258 IV. EFFECTS OF
METHACHOLINE 260 A. ENDOTHELIUM-DENUDED RINGS 260 B. ENDOTHELIUM-INTACT
RINGS 261 V. EFFECTS OF POTASSIUM 263 VI. DISCUSSION 263 REFERENCES 266
VOLATILE ANESTHETICS AND CORONARY COLLATERAL CIRCULATION JUDY R.
KERSTEN, J. CRAIG HARTMAN, PAUL S. PAGEL, AND DAVID C. WARLTIER I.
INTRODUCTION 269 II. CHRONIC ANIMAL INSTRUMENTATION 270 III. REGIONAL
MYOCARDIAL FUNCTION AND PERFUSION 271 IV. CORONARY STEAL PRONE ANATOMY
MODEL 273 V. HEMODYNAMIC EFFECTS OF ISOFLURANE, SEVOFLURANE, AND
ADENOSINE 275 VI. REGIONAL MYOCARDIAL PERFUSION: ISOFLURANE,
SEVOFLURANE, AND ADENOSINE 278 VII. DISCUSSION 280 REFERENCES 283
MYOCARDIAL OXYGEN SUPPLY*DEMAND RELATIONS DURING ISOVOLEMIC HEMODILUTION
GEORGE J. CRYSTAL I. INTRODUCTION 285 II. EXPERIMENTAL STUDIES 286 A.
LIMIT TO CARDIAC COMPENSATION DURING ISOVOLEMIC HEMODILUTION: INFLUENCE
OF CORONARY STENOSIS 286 B. COMPARISON OF EFFECTS OF ISOVOLEMIC
HEMODILUTION IN RIGHT AND LEFT VENTRICLES 300 C. CARDIAC EFFECTS OF
COMBINED ISOVOLEMIC HEMODILUTION AND CONTROLLED HYPOTENSION 308 HI.
SUMMARY 311 REFERENCES 311 XLL CONTENTS PART III CELLULAR TARGETS PLASMA
MEMBRANE CA 2 + -ATPASE AS A TARGET FOR VOLATILE ANESTHETICS DANUTA
KOSK-KOSICKA I. INTRODUCTION 313 II. ISOLATION AND ACTIVITY ASSAY OF CA
2+ -ATPASE 315 III. EFFECTS OF ANESTHETICS 316 IV. DISCUSSION 320
REFERENCES 321 ENHANCEMENT OF HALOTHANE ACTION AT THE RYANODINE RECEPTOR
BY UNSATU RATED FATTY ACIDS JEFFREY E. FLETCHER AND VINCENT E. WELTER I.
INTRODUCTION 323 II. CALCIUM EFFLUX 324 III. CALCIUM RELEASE FROM HEAVY
SARCOPLASMIC RETICULUM FRACTION 325 A. EFFECTS OF FATTY ACIDS IN ABSENCE
OF HALOTHANE IN RAT CARDIAC MUSCLE 325 B. INTERACTION BETWEEN FATTY
ACIDS AND HALOTHANE IN RAT CARDIAC MUSCLE 325 C. DISPLACEMENT OF FATTY
ACIDS FROM BINDING SITES BY HALOTHANE 326 IV. DISCUSSION 328 REFERENCES
330 ADRENERGIC RECEPTORS: UNIQUE LOCALIZATION IN HUMAN TISSUES DEBRA A.
SCHWINN I. INTRODUCTION 333 II. METHODS USED TO STUDY RECEPTOR
DISTRIBUTION 337 III. LOCALIZATION OF RECEPTORS IN HUMAN TISSUE 338 IV.
SUMMARY 340 REFERENCES 341 VOLATILE ANESTHETIC EFFECTS ON INOSITOL
TRIPHOSPHATE-GATED INTRACELLULAR CALCIUM STORES IN GH 3 CELLS ALEX S.
EVERS AND M. DELAWAR HOSSAIN I. INTRODUCTION 343 II. INTRACELLULAR
CALCIUM MEASUREMENTS 344 CONTENTS XIII III. EFFECTS OF ANESTHETICS 345
A. TRH-STIMULATED INOSITOL PHOSPHATE ACCUMULATION 345 B. EFFECTS OF
HALOTHANE ON RESTING INTRACELLULAR CALCIUM 345 C. EFFECTS OF HALOTHANE
ON TRH-STIMULATED INCREASES IN INTRACELLULAR CALCIUM 346 D. MECHANISM OF
HALOTHANE INHIBITION OF PEAK INTRACELLULAR CALCIUM RESPONSES TO TRH 347
E. EFFECTS OF ISOFLURANE AND OCTANOL ON PEAK INTRACELLULAR CALCIUM
RESPONSE TO TRH 349 IV. SUMMARY 349 REFERENCES 350 PART IV REFLEX
REGULATION DIFFERENTIAL CONTROL OF BLOOD PRESSURE BY TWO SUBTYPES OF
CAROTID BARORECEPTORS JEANNE L. SEAGARD I. INTRODUCTION 351 II. CAROTID
BARORECEPTORS 353 A. ANODAL BLOCK 354 B. ANESTHETIC BLOCK 355 C.
BARORECEPTOR ACTIVATION 355 HI. CAROTID SINUS NERVE ACTIVITY 357 A.
BLOCKING OF NORMAL ACTIVITY BY ANODAL CURRENT 357 B. BLOCK OF NERVE
ACTIVITY BY ANESTHETIC 359 IV. DISCUSSION 361 V. ANESTHETIC IMPLICATIONS
364 REFERENCES 366 SYMPATHETIC ACTIVATION WITH DESFLURANE IN HUMANS
THOMAS J. EBERT AND MICHAEL MUZI I. INTRODUCTION 369 II. SYMPATHETIC
MICRONEUROGRAPHY 370 III. ANESTHETICS AND SYMPATHETIC ACTIVATION 371 IV.
DISCUSSION 375 A. INDUCTION RESPONSES 375 B. STEADY-STATE RESPONSES 376
C. TRANSITION RESPONSES 376 XIV CONTENTS V. SUMMARY 377 REFERENCES 378
RANDOMIZED, PROSPECTIVE COMPARISON OF HALOTHANE, ISOFLURANE, AND
ENFLURANE ON BAROREFLEX CONTROL OF HEART RATE IN HUMANS MICHAEL MUZI AND
THOMAS J. EBERT I. INTRODUCTION 379 II. BAROREFLEX FUNCTION IN HUMANS
380 III. EFFECTS OF ANESTHETICS 381 IV. DISCUSSION 383 REFERENCES 386
BAROREFLEX MODULATION BY ISOFLURANE ANESTHESIA IN NORMOTENSIVE AND
CHRONICALLY HYPERTENSIVE RABBITS LEONARD B. BELL I. INTRODUCTION 389 II.
CHRONICALLY HYPERTENSIVE RABBIT MODEL AND EXPERIMENTAL PROTOCOL 390 HI.
EFFECT OF ISOFLURANE ON ARTERIAL PRESSURE-RENAL SYMPATHETIC NERVE
ACTIVITY AND ARTERIAL PRESSURE-HEART RATE BAROCURVES 394 A. MEAN
ARTERIAL PRESSURE-RENAL SYMPATHETIC NERVE ACTIVITY BAROREFLEXES 396 B.
MEAN ARTERIAL PRESSURE-HEART RATE BAROREFLEXES 398 IV. DISCUSSION 401 A.
EFFECT OF ISOFLURANE ANESTHESIA ON ARTERIAL PRESSURE-HEART RATE
BAROREFLEX 401 B. EFFECT OF ISOFLURANE ANESTHESIA ON ARTERIAL
PRESSURE-RENAL SYMPATHETIC NERVE ACTIVITY BAROREFLEX 402 C. EFFECT OF
ISOFLURANE ON STEADY-STATE RESTING LEVELS OF RENAL SYMPATHETIC NERVE
ACTIVITY AND HEART RATE 402 D. EFFECT OF CHRONIC HYPERTENSION ON MEAN
ARTERIAL PRESSURE-HEART RATE BAROREFLEX 402 E. EFFECT OF CHRONIC
HYPERTENSION ON MEAN ARTERIAL PRESSURE-RENAL SYMPATHETIC NERVE ACTIVITY
BAROREFLEX 403 F. EFFECT OF CHRONIC HYPERTENSION ON STEADY-STATE RESTING
LEVELS OF RENAL SYMPATHETIC NERVE ACTIVITY AND HEART RATE 404 G.
INTERACTION OF ISOFLURANE ANESTHESIA AND CHRONIC HYPERTENSION ON
BAROREFLEX FUNCTION 405 REFERENCES 406 CONTENTS XV PARTV PERIPHERAL
CIRCULATION EFFECTS OF ISOFLURANE ON REGULATION OF CAPACITANCE VESSELS
UNDER NORMOTENSIVE AND CHRONICALLY HYPERTENSIVE CONDITIONS THOMAS A.
STEKIEL, LEONARD B. BELL, ZELJKO J. BOSNJAK, AND JOHN P. KAMPINE I.
INTRODUCTION 409 II. HYPERTENSIVE RABBIT PREPARATION 411 III. MESENTERIC
REFLEX MEASUREMENTS 411 IV. CIRCULATORY RESPONSES TO BAROREFLEX AND
CHEMOREFLEX RESPONSES IN NORMOTENSIVE AND HYPERTENSIVE ANIMALS 413 V.
EFFECTS OF ISOFLURANE ON HYPOXIA AND BAROREFLEX- MEDIATED RESPONSES 419
VI. EFFECTS OF ISOFLURANE ON PRESTIMULATION BASELINE MEASUREMENTS 421
VII. DISCUSSION 421 REFERENCES 428 EFFECT OF VOLATILE ANESTHETICS ON
BAROREFLEX CONTROL OF MESENTERIC VENOUS CAPACITANCE J. BRUCE MCCALLUM,
THOMAS A. STEKIEL, ANNA STADNICKA, ZELJKO J. BOSNJAK, AND JOHN P.
KAMPINE I. INTRODUCTION 431 II. MEASUREMENT OF VENOUS CAPACITANCE 432
III. RESPONSE TO BARORECEPTOR STIMULATON 434 IV. RESPONSE TO ELECTRIC
STIMULATION 440 V. DISCUSSION 440 REFERENCES 446 EFFECT OF GENERAL
ANESTHESIA ON MODULATION OF SYMPATHETIC NERVOUS SYSTEM FUNCTION MARGARET
WOOD I. INTRODUCTION 449 II. EFFECT OF INTRAVENOUS AND INHALATIONAL
ANESTHETICS ON NOREPINEPHRINE KINETICS 450 III. J8-ADRENERGIC
RECEPTOR-MEDIATED RELEASE OF NOREPINEPHRINE 454 XVI CONTENTS IV. EFFECT
OF INHALATIONAL ANESTHESIA ON PREJUNCTIONAL NOREPINEPHRINE RELEASE IN
VIVO 456 V. CONCLUSIONS 457 REFERENCES 457 INHIBITION OF NITRIC
OXIDE-DEPENDENT VASODILATON BY HALOGENATED ANESTHETICS MING JING, JAYNE
L. HART, SAIID BINA, AND SHEILA M. MULDOON I. INTRODUCTION 459 II.
METHODS 460 III. EFFECTS OF ANESTHETICS ON ENDOTHELIUM-DEPENDENT
RELAXATIONS OF ISOLATED BLOOD VESSELS 462 IV. EFFECTS OF HALOTHANE AND
ISOFLURANE ON NITRIC OXIDE-, NITROGLYCERIN-, AND CARBON MONOXIDE-INDUCED
RELAXATIONS OF RAT AORTA 463 V. EFFECTS OF HALOTHANE ON NITRIC
OXIDE-STIMULATED CYCLIC GMP 464 VI. INTERACTIONS OF HALOTHANE AND NITRIC
OXIDE IN ABSENCE OF TISSUES 465 VII. DISCUSSION 467 REFERENCES 469
EFFECTS OF EPIDURAL ANESTHESIA ON SPLANCHNIC CAPACITANCE QUINN H. HOGAN,
ANNA STADNICKA, AND JOHN P. KAMPINE I. INTRODUCTION 471 II. EPIDURAL
ANESTHESIA 472 III. SPLANCHNIC CAPACITANCE 473 IV. SUMMARY 482
REFERENCES 482 ANESTHETIC MODULATION OF PULMONARY VASCULAR REGULATION
PAUL A. MURRAY I. INTRODUCTION 485 II. MEASUREMENT OF PULMONARY
VASOREGULATION 486 A. SURGICAL PREPARATION FOR CHRONIC INSTRUMENTATION
486 B. PHYSIOLOGICAL MEASUREMENTS 486 C. GENERATION OF PULMONARY
VASCULAR PRESSURE-FLOW PLOTS 487 D. GENERAL PROTOCOLS 487 III.
ANESTHESIA AND PULMONARY VASOREGULATION 488 A. EFFECTS OF ANESTHESIA ON
BASELINE PRESSURE-FLOW RELATIONSHIP 488 B. ANESTHESIA AND AUTONOMIC
NERVOUS SYSTEM REGULATION OF PRESSURE-FLOW RELATIONSHIP 490 CONTENTS
XVII C. ANESTHESIA AND HUMORAL REGULATION OF PRESSURE-FLOW RELATIONSHIP
493 D. ANESTHESIA AND REGULATION OF THE PRESSURE-FLOW RELATIONSHIP BY
CYCLOOXYGENASE METABOLITES 494 E. ANESTHESIA AND PULMONARY VASCULAR
RESPONSE TO HYPOPERFUSION 495 F. ANESTHESIA AND ENDOTHELIUM-DEPENDENT
AND -INDEPENDENT PULMONARY VASODILATION 498 IV. SUMMARY 502 REFERENCES
503 PULMONARY MECHANICS CHANGES ASSOCIATED WITH CARDIAC SURGERY RON
DUECK I. INTRODUCTION 505 II. DYNAMIC LUNG COMPLIANCE 506 III. EFFECTS
OF STERNOTOMY 506 IV. DISCUSSION 509 REFERENCES 512 INHALED NITRIC OXIDE
IN ADULT RESPIRATORY DISTRESS SYNDROME AND OTHER LUNG DISEASES WARREN M.
ZAPOL AND WILLIAM E. HURFORD I. INTRODUCTION 513 II. PULMONARY
HYPERTENSION IN ADULT RESPIRATORY DISTRESS SYNDROME 514 III. NITRIC
OXIDE 514 IV. RATIONALE FOR USE OF INHALED NITRIC OXIDE IN PATIENTS WITH
ADULT RESPIRATORY DISTRESS SYNDROME 515 V. LABORATORY STUDIES OF INHALED
NITRIC OXIDE 515 A. ACUTE PULMONARY HYPERTENSION 515 B. BRONCHODILATION
518 VI. CLINICAL STUDIES OF NITRIC OXIDE INHALATION IN ADULT RESPIRATORY
DISTRESS SYNDROME 519 VII. INHALED NITRIC OXIDE IN OTHER LUNG DISEASES
ASSOCIATED WITH PULMONARY HYPERTENSION 522 A. NEONATAL RESPIRATORY
FAILURE 522 B. CHRONIC PULMONARY HYPERTENSION 523 C. CONGENITAL AND
ACQUIRED HEART DISEASE 523 VIII. TOXICITY OF NITRIC OXIDE 524 IX.
GUIDELINES FOR NITRIC OXIDE INHALATION 525 REFERENCES 527 XVIII CONTENTS
FIRST PASS UPTAKE IN THE HUMAN LUNG OF DRUGS USED DURING ANESTHESIA
DAVID L. ROERIG, SUSAN B. AHLF, CHRISTOPHER A. DAWSON, JOHN H. LINEHAN,
AND JOHN P. KAMPINE I. INTRODUCTION 531 II. FIRST PASS DRUG UPTAKE IN
HUMAN LUNG 532 III. FACTORS AFFECTING PULMONARY DRUG UPTAKE 538 A.
SATURABILITY 538 B. PLASMA PROTEIN BINDING 542 C. EFFECT OF CARDIAC
OUTPUT 545 IV. CONCLUSIONS 547 REFERENCES 547 LACTIC ACIDOSIS AND PH ON
THE CARDIOVASCULAR SYSTEM YUGUANG HUANG, JAMES B. YEE, WANG-HIN YIP, AND
K. C. WONG I. INTRODUCTION 551 II. INDUCTION OF LACTIC ACIDOSIS 552 III.
CARDIOVASCULAR EFFECTS OF ACUTE ACIDOSIS 554 IV. DISCUSSION 562
REFERENCES 564 PART VI CEREBRAL CIRCULATION ROLE OF OXYGEN FREE RADICALS
AND LIPID PEROXIDATION IN CEREBRAL REPERFUSION INJURY LAUREL E. MOORE
AND RICHARD J. TRAYSTMAN I. INTRODUCTION 565 II. FREE RADICALS 566 III.
MECHANISMS OF BRAIN INJURY 567 IV. POTENTIAL THERAPEUTIC AGENTS 568 V.
CONCLUSION 571 REFERENCES 572 CONTENTS XIX EFFECTS OF VOLATILE
ANESTHETICS ON CEREBROCORTICAL LASER DOPPLER FLOW: HYPEREMIA,
AUTOREGULATION, CARBON DIOXIDE RESPONSE, FLOW OSCILLATIONS, AND ROLE OF
NITRIC OXIDE ANTAL G. HUDETZ, JOSEPH G. LEE, JEREMY J. SMITH, ZELJKO J.
BOSNJAK, AND JOHN P. KAMPINE I. INTRODUCTION 577 II. MEASUREMENT OF
LASER DOPPLER FLOW 579 III. RESTING FLOW 581 IV. AUTOREGULATION 582 V.
HYPOCAPNIA AND HYPERCAPNIA 584 VI. ROLE OF NITRIC OXIDE 586 VII.
SPONTANEOUS FLOW OSCILLATIONS 588 VIII. CONCLUSIONS 591 REFERENCES 591
CEREBRAL BLOOD FLOW DURING ISOVOLEMIC HEMODILUTION: MECHANISTIC
OBSERVATIONS MICHAEL M. TODD I. INTRODUCTION 595 II. INFLUENCE OF
HEMODILUTON ON CEREBRAL BLOOD VOLUME 596 III. INFLUENCE OF FOCAL
CORTICAL BRAIN LESION ON REGIONAL CEREBRAL BLOOD FLOW RESPONSE TO
HEMODILUTION 597 IV. COMPARISON OF CEREBROVASCULAR AND METABOLIC CHANGES
PRODUCED BY HYPOXIA AND HEMODILUTION 599 V. ROLE OF NITRIC OXIDE IN THE
CEREBRAL BLOOD FLOW RESPONSE TO HEMODILUTION 602 VI. DISCUSSION 603
REFERENCES 603 CEREBRAL PHYSIOLOGY DURING CARDIOPULMONARY BYPASS:
PULSATILE VERSUS NONPULSATILE FLOW BRAD HINDMAN I. INTRODUCTION 607 II.
PULSATILE VERSUS NONPULSATILE BYPASS 610 III. INFLUENCE OF ARTERIAL
PRESSURE WAVEFORM 611 IV. SUMMARY 614 REFERENCES 614 XX CONTENTS
ANESTHETIC ACTIONS OF CARDIOVASCULAR CONTROL MECHANISMS IN THE CENTRAL
NERVOUS SYSTEM WILLIAM T. SCHMELING AND NEIL E. FARBER I. INTRODUCTION
617 II. STUDIES PERFORMED IN CATS 619 A. PREPARATION FOR ACUTE STUDIES
619 B. PREPARATION FOR STUDIES OF INTERMEDIOLATERAL CELL COLUMN EVOKED
POTENTIALS 620 III. STUDIES IN MONGREL DOGS 621 IV. CENTRAL NERVOUS
SYSTEM PRESSOR SITE RESPONSES IN CATS AND INTERMEDIOLATERAL CELL COLUMN
EVOKED POTENTIAL 623 V. ANESTHETIC RESPONSES IN DOGS 625 VI.
HISTOLOGICAL DOCUMENTATION OF ELECTRODE SITES 634 VII. DISCUSSION 634
REFERENCES 639 INDEX 643 CONTENTS OF PREVIOUS VOLUMES 655
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| id | DE-604.BV010042516 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T17:45:27Z |
| institution | BVB |
| isbn | 0120329328 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-006660240 |
| oclc_num | 31682232 |
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| physical | XXX, 666 S. Ill., graph Darst. |
| publishDate | 1994 |
| publishDateSearch | 1994 |
| publishDateSort | 1994 |
| publisher | Acad. Press |
| record_format | marc |
| series2 | Advances in pharmacology |
| spelling | Anesthesia and cardiovascular disease ed. by Zeljko J. Bosnjak ... San Diego [u.a.] Acad. Press 1994 XXX, 666 S. Ill., graph Darst. txt rdacontent n rdamedia nc rdacarrier Advances in pharmacology 31 Einzelaufnahme eines Zeitschr.-Bd. Anesthesie gtt Fysiologie gtt Hart gtt Anesthetics Physiological effect Anesthetics pharmacology Heart Effect of drugs on Heart drug effects Narkotikum (DE-588)4171167-1 gnd rswk-swf Narkoseführung (DE-588)4200073-7 gnd rswk-swf Arzneimittelnebenwirkung (DE-588)4003134-2 gnd rswk-swf Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd rswk-swf Anästhesie (DE-588)4001833-7 gnd rswk-swf Anästhesie (DE-588)4001833-7 s Kardiovaskuläre Krankheit (DE-588)4024666-8 s DE-604 Narkotikum (DE-588)4171167-1 s Arzneimittelnebenwirkung (DE-588)4003134-2 s Narkoseführung (DE-588)4200073-7 s Bosnjak, Zeljko J. Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006660240&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Anesthesia and cardiovascular disease Anesthesie gtt Fysiologie gtt Hart gtt Anesthetics Physiological effect Anesthetics pharmacology Heart Effect of drugs on Heart drug effects Narkotikum (DE-588)4171167-1 gnd Narkoseführung (DE-588)4200073-7 gnd Arzneimittelnebenwirkung (DE-588)4003134-2 gnd Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Anästhesie (DE-588)4001833-7 gnd |
| subject_GND | (DE-588)4171167-1 (DE-588)4200073-7 (DE-588)4003134-2 (DE-588)4024666-8 (DE-588)4001833-7 |
| title | Anesthesia and cardiovascular disease |
| title_auth | Anesthesia and cardiovascular disease |
| title_exact_search | Anesthesia and cardiovascular disease |
| title_full | Anesthesia and cardiovascular disease ed. by Zeljko J. Bosnjak ... |
| title_fullStr | Anesthesia and cardiovascular disease ed. by Zeljko J. Bosnjak ... |
| title_full_unstemmed | Anesthesia and cardiovascular disease ed. by Zeljko J. Bosnjak ... |
| title_short | Anesthesia and cardiovascular disease |
| title_sort | anesthesia and cardiovascular disease |
| topic | Anesthesie gtt Fysiologie gtt Hart gtt Anesthetics Physiological effect Anesthetics pharmacology Heart Effect of drugs on Heart drug effects Narkotikum (DE-588)4171167-1 gnd Narkoseführung (DE-588)4200073-7 gnd Arzneimittelnebenwirkung (DE-588)4003134-2 gnd Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Anästhesie (DE-588)4001833-7 gnd |
| topic_facet | Anesthesie Fysiologie Hart Anesthetics Physiological effect Anesthetics pharmacology Heart Effect of drugs on Heart drug effects Narkotikum Narkoseführung Arzneimittelnebenwirkung Kardiovaskuläre Krankheit Anästhesie |
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