Bioactive compounds: biotransformation and biological action
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York
Nova Science Publ.
1993
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | IX, 291 S. graph. Darst. |
| ISBN: | 1560720751 |
Internformat
MARC
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| 245 | 1 | 0 | |a Bioactive compounds |b biotransformation and biological action |c ed. by I. N. Todorov ... |
| 264 | 1 | |a New York |b Nova Science Publ. |c 1993 | |
| 300 | |a IX, 291 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 650 | 4 | |a Bioactive compounds |x Metabolism | |
| 650 | 4 | |a Biotransformation | |
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Datensatz im Suchindex
| _version_ | 1804124361129459712 |
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| adam_text | BIOACTIVE COMPOUNDS BLOTRANSFORMATION AND BIOLOGICAL ACTION EDITED BY
I.N. TODOROV, G.E. ZAIKOV, AND LA. DEGTEREV NOVA SCIENCE PUBLISHERS,
INC. CONTENTS PREFACE XI CONTRIBUTORS :. XIII MECHANISM OF ANTISTRESS
AND ANABOLIC ACTIONS OF ELEUTHEROCOCCUS SENTICOSUS MAXIMUM EXTRACTS THE
KEY ROLE OF BIOGENESIS MODULATION OF CORTICOSTEROIDS I.N. TODOROV
INTRODUCTION 1 1. CHEMICAL AND PHYSICOCHEMICAL PROPERTIES OF
ELEUTHEROCOCCUS 3 1.1 CHEMICAL COMPOSITION OF ELEUTHEROCOCCUS EXTRACTS.
STRUCTURE OF ELEUTHEROSIDES 3 1.2 CONFORMATION OF ELEUTHEROSIDES 5 1.3
FLUORESCENCE-ABSORPTION CHARACTERISTICS OF ELEUTHEROSIDES 9 2.
PHARMACOLOGICAL PROPERTIES OF ELEUTHEROCOCCUS EXTRACTS .- : 12 2.1
ELEUTHEROCOCCUS. A PREVENTATIVE AGENT..:. 12 2.2 DECREASE IN TOXICITY OF
CHEMICAL COMPOUNDS 15 2.3 DECREASE IN MORBIDITY RATES 15 2.4
ELEUTHEROCOCCUS AS A DRUG 16 3. BIOLOGICAL ACTIVITY OF ELEUTHEROCOCCUS
EXTRACT AND ITS ELEUTHEROSIDES : 17 3.1 SYSTEMIC ANABOLIC EFFECT 17 3.2
BIOSYNTHESIS OF PROTEINS AND NUCLEIC ACIDS 18 3.3 IMMUNOGENESIS 20 3.4
INTERFERON BIOSYNTHESIS 21 3.5 CARBOHYDRATE METABOLISM 22 3.6 LIPID
METABOLISM 28 3.7 ANTIMUTAGENIC AND ANTITERATOGENIC EFFECTS 28 3.8
ANTISTRESS ACTION 30 V STUDY OF THE PHARMACOKINETLCS AND THE MECHANISM
OF ACTION OF ELEUTHEROCOCCUS GLYCOSIDES 32 4.1 INCORPORATION OF TRITIUM
IN ELEUTHEROSIDE B. KINETICS OF ITS ACCUMULATION AND ELIMINATION FROM
THE ANIMAL BODY 32 4.2 DISTRIBUTION OF ELEUTHEROSIDE B IN ORGANS AND
SUBCELLULAR FRACTIONS 38 4.3 METABOLISM AND KINETICS OF BINDING TO BLOOD
SERUM COMPONENTS 44 4.4 EFFECT OF EXTRACT AND INDIVIDUAL GLYCOSIDES ON
PROTEIN BIOSYNTHESIS IN VITRO 50 4.5 IN VIVO EFFECTS OF ELEUTHEROCOCCUS
EXTRACT ON PROTEIN METABOLISM AND BIOSYNTHESIS IN SOME ORGANS AND
TISSUES 56 REFERENCES 67 BIOLOGICAL ACTIVITY OF DIAZOKETONES. AN
ANALYTICAL REVIEW OF THE LITERATURE FROM 1954 TO 1989 VICTOR G. KARTSEV
AND V.S. DOMBROVSKY INTRODUCTION 79 I. MONODIAZOKETONES 79 1.1
BIOLOGICAL ACTIVITY 79 1.2 ANTITUMOR ACTIVITY 85 1.3 PHARMACOKINETICS OF
DIAZOKETONES 87 1.4 CANCEROGENESIS 89 1.5 MUTAGENESIS 90 1.6
TERATOGENESIS ., 91 1.7 MECHANISM OF RESISTANCE :. 93 1.8 TRANSPORT OF
DIAZOKETONES INTO A CELL AND ITS RELATION TO THE ACTIVE TRANSPORT OF
AMINO ACIDS THROUGH CELL MEMBRANES 94 1.9 EFFECT OF DIAZOKETONES ON CELL
ADHESION 95 1.10 EFFECT OF DIAZOKETONES ON THE IMMUNOSYSTEM 95 1.11
INHIBITION OF ENZYMES IN VITRO AND IN VIVO BY DIAZOKETONE INHIBITION OF
PURINES DE NOVA SYNTHESIS 96 1.12 DIAZOKETONES AS INHIBITORS OF SOME
ENZYMES 97 L .13 INHIBITION OF ACID PROTEASES BY DIAZOKETONES IN THE
PRESENCE OF COPPER(II) SALTS 103 VI II. BISDIAZOKETONES 107 II. 14
MUTAGENEOUS PROPERTIES OF BISDIAZOKETONES 107 11.15 TOXICITY AND
ANTITUMOR ACTIVITY OF DIAZINE 109 CONCLUSIONS 119 REFERENCES ...119
KINETICS AND MECHANISMS OF MICROSOMAL METABOLISM OF NITROHETEROCYCLIC
COMPOUNDS-5- NITROFURAN AND 1-NITROACRIDINE DERIVATIVES AND RELATIONSHIP
WITH BIOLOGICAL ACTIVITY OF THESE COMPOUNDS IGOR A. DEGTEREV, NADEZHDA
K. TATARSKAYA AND GENNADII E ZAIKOV INTRODUCTION 155 BIOLOGICAL ACTIVITY
OF 5-NITROFURAN AND 1 -NITROACRIDINE DERIVATIVES AND THE ROLE OF
METABOLIC ACTIVATION 156 EFFECT OF THE STRUCTURE OF FURAN AND ACRIDINE
DERIVATIVES ON THE KINETIC PARAMETERS OF THEIR METABOLISM IN LIVER AND
TUMOR MICROSOMES 164 RELATIONSHIP BETWEEN BIOLOGICAL ACTIVITY OF
5-NITROFURAN AND 1-NITROACRIDINE DERIVATIVES AND THEIR STRUCTURE 179
MECHANISMS OF METABOLIC TRANSFORMATION OF 5-NITROFURAN AND
1-NITROACRIDINE DERIVATIVES IN MICROSOMES OF LIVER AND TUMOR CELLS 182
DIFFERENCES IN XENOBIOTIC-METABOLIZING ACTIVITY OF MICROSOMES OF LIVER
AND TUMOR I 189 CONCLUSION 190 REFERENCES 191 VLL FUNDAMENTAL
POSSIBILITIES OF MODULATING MICROSOMAL METABOLISM OF NITROHETEROCYCLIC
COMPOUNDS: PROSPECTS FOR CONTROLLING THEIR THERAPEUTIC EFFECTS. IGOR A.
DEGTEREV, ELENA YU. LEONOVA, AND GENNADII E. ZAIKOV INTRODUCTION 201 THE
EFFECT OF ASCORBIC ACID (AA) AND GLUTATHIONE (GSH) ON BIOLOGICAL ACTION
OF NHCC 202 EFFECT OF AA AND GSH ON MICROSOMAL METABOLISM OF NHCC 204
THE EFFECT OF BLOCKING OF NHCC MICROSOMAL METABOLISM IN THE PRESENCE OF
ADRENALIN AND RELATED COMPOUNDS 213 INDUCTION OF XENOBIOTIC-METABOLIZING
ENZYMES OF ANIMAL LIVER BY FOOD ANTIOXIDANT BHT LEADS TO THE CHANGE IN
NHCC MICROSOMAL METABOLISM 220 CONCLUSION 225 REFERENCES 226 MECHANISM
OF MICROSOMAL OXIDATION OF ADRENALIN IGOR A. DEGTEREV, ELENA YU.
LEONOVA, AND NADEZHDA K. TATARSKAYA , INTRODUCTION 235 THE BIOLOGICAL
PROPERTIES AND METABOLIC PATHWAYS OF ADRENALIN 235 CHEMISTRY OF
ADRENALIN AND ITS OXIDATION PRODUCTS 236 BIOLOGICAL OXIDATION OF
ADRENALIN IN VITRO 237 EVIDENCE OF THE DIRECT PARTICIPATION OF
CYTOCHROME P-450 IN ADRENALIN MICROSOMAL OXIDATION 239 CONCLUSION 252
REFERENCES 252 VUI BIOTRANSFORMATION OF ANTITUMOR ALKYINITROSOUREAS
VICTOR G. SHARF INTRODUCTION 257 HYDROLYTIC DECOMPOSITION 258 MECHANISMS
AND KINETICS 258 ACTIVE INTERMEDIATES 264 METABOLIC TRANSFORMATIONS 265
HYDROXYLATION 266 DENITRPSATION 267 OTHER METABOLIC PATHWAYS 274
ACKNOWLEDGEMENT 276 REFERENCES 276 IX
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| illustrated | Illustrated |
| indexdate | 2024-07-09T17:44:26Z |
| institution | BVB |
| isbn | 1560720751 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-006619067 |
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| physical | IX, 291 S. graph. Darst. |
| publishDate | 1993 |
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| publisher | Nova Science Publ. |
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| spelling | Bioactive compounds biotransformation and biological action ed. by I. N. Todorov ... New York Nova Science Publ. 1993 IX, 291 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Bioactive compounds Metabolism Biotransformation Biotransformation (Metabolism) Pharmaceutical Preparations metabolism Bioaktive Verbindungen (DE-588)4145589-7 gnd rswk-swf Biotransformation (DE-588)4006908-4 gnd rswk-swf Bioaktive Verbindungen (DE-588)4145589-7 s DE-604 Biotransformation (DE-588)4006908-4 s Todorov, Igor N. Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006619067&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Bioactive compounds biotransformation and biological action Bioactive compounds Metabolism Biotransformation Biotransformation (Metabolism) Pharmaceutical Preparations metabolism Bioaktive Verbindungen (DE-588)4145589-7 gnd Biotransformation (DE-588)4006908-4 gnd |
| subject_GND | (DE-588)4145589-7 (DE-588)4006908-4 |
| title | Bioactive compounds biotransformation and biological action |
| title_auth | Bioactive compounds biotransformation and biological action |
| title_exact_search | Bioactive compounds biotransformation and biological action |
| title_full | Bioactive compounds biotransformation and biological action ed. by I. N. Todorov ... |
| title_fullStr | Bioactive compounds biotransformation and biological action ed. by I. N. Todorov ... |
| title_full_unstemmed | Bioactive compounds biotransformation and biological action ed. by I. N. Todorov ... |
| title_short | Bioactive compounds |
| title_sort | bioactive compounds biotransformation and biological action |
| title_sub | biotransformation and biological action |
| topic | Bioactive compounds Metabolism Biotransformation Biotransformation (Metabolism) Pharmaceutical Preparations metabolism Bioaktive Verbindungen (DE-588)4145589-7 gnd Biotransformation (DE-588)4006908-4 gnd |
| topic_facet | Bioactive compounds Metabolism Biotransformation Biotransformation (Metabolism) Pharmaceutical Preparations metabolism Bioaktive Verbindungen |
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