Immunosuppressive and antiinflammatory drugs: [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida]
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
New York, NY
New York Acad. of Sciences
1993
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Schriftenreihe: | Annals of the New York Academy of Sciences
696 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Literaturangaben |
Beschreibung: | XX, 424 S. Ill., graph. Darst. |
ISBN: | 0897668359 0897668367 |
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adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES VOLUME 696 IMMUNOSUPPRESSIVE
AND ANTIINFLAMMATORY DRUGS EDITED BY ANTHONY C. ALLISON, KEVIN J.
LAJFERTY, AND HANS FLIRI THE NEW YORK ACADEMY OF SCIENCES NEW YORK, NEW
YORK 1993 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES VOLUME 696 NOVEMBER
30, 1993 IMMUNOSUPPRESSIVE AND ANTIINFLAMMATORY DRUGS* EDITORS AND
CONFERENCE ORGANIZERS ANTHONY C. ALLISON, KEVIN J. LAFFERTY, AND HANS
FLIRI CONTENTS NOVEL IMMUNOSUPPRESSIVE AND ANTIINFLAMMATORY DRUGS: A
1993 PERSPECTIVE. BY ANTHONY C. ALLISON XI PART I. IMMUNOBIOLOGY OF
CYCLOSPORINS, FK-506, AND RAPAMYCIN IMMUNOSUPPRESSIVE PROFILE OF
RAPAMYCIN. BY SUREN N. SEHGAL 1 THE MECHANISM OF ACTION OF FK-506 AND
CYCLOSPORIN A. BY GREG WIEDERRECHT, ELSA LAM, SHIRLEY HUNG, MARY MARTIN,
AND NOLAN SLGAL 9 CALCINEURIN IS A KEY SIGNALING ENZYME IN T LYMPHOCYTE
ACTIVATION AND THE TARGET OF THE IMMUNOSUPPRESSIVE DRUGS CYCLOSPORIN A
AND FK506. BY NEIL A. CLIPSTONE AND GERALD R. CRABTREE 20 RAPAMYCIN
INHIBITS P34 CDC2 EXPRESSION AND ARRESTS T LYMPHOCYTE PROLIFERATION AT
THE GL/S TRANSITION. BY W. MICHAEL FLANAGAN AND GERALD R. CRABTREE 31
PROLINE ISOMERASES IN MICROORGANISMS AND SMALL EUKARYOTES. BY CHARLES
HEMENWAY AND JOSEPH HEITMAN 38 CYCLOSPORINS: STRUCTURE-ACTIVITY
RELATIONSHIPS. BY HANS FLIRI, GOETZ BAUMANN, ALBERT ENZ, JUERG KALLEN,
MARCEL LUYTEN, VINCENT MIKOL, RAO MOVVA, VALERIE QUESNIAUX, MAX
SCHREIER, MALCOLM WALKINSHAW, ROLAND WENGER, GERHARD ZENKE, AND
MAUROZURINI 47 AN FKBP-RAPAMYCIN-SENSITIVE, CYCLIN-DEPENDENT KINASE
ACTIVITY THAT CORRELATES WITH THE FKBP-RAPAMYCIN-INDUCED GL ARREST POINT
IN MG-63 CELLS. BY MARK W. ALBERS, ERIC J. BROWN, AKITO TANAKA, RICHARD
T. WILLIAMS, FREDERICK L. HALL, AND STUART L. SCHREIBER ... 54 PART II.
NOVEL IMMUNOSUPPRESSIVE DRUGS MECHANISMS OF ACTION OF MYCOPHENOLIC ACID.
BY ANTHONY C. ALLISON, W. JOSEPH KOWALSKI, CHRISTIAN D. MULLER, AND
ELSIE M. EUGUI 63 THIS VOLUME IS THE RESULT OF A CONFERENCE ENTITLED
IMMUNOSUPPRESSIVE AND ANTIINFLAMMA- TORY DRUGS HELD ON APRIL 12-15, 1993
IN ORLANDO, FLORIDA AND SPONSORED BY THE NEW YORK ACADEMY OF SCIENCES.
HUMAN TYPE I AND II IMP DEHYDROGENASES AS DRUG TARGETS. BY YUTAKA
NATSUMEDA AND STEPHEN F. CARR IMMUNOSUPPRESSION BY DISCODERMOLIDE. BY
ROSS E. LONGLEY, SARATH P. GUNASEKERA, DENISE FAHERTY, JOHN MCLANE, AND
FRANCIS DUMONT.. 94 BREQUINAR SODIUM, MYCOPHENOLIC ACID, AND CYCLOSPORIN
A INHIBIT DIFFERENT STAGES OF IL-4- OR IL-13-INDUCED HUMAN IGG4 AND IGE
PRODUCTION IN VITRO. BY CHIA-CHUN J. CHANG, GREGORIO AVERSA, JUHA
PUNNONEN, HANS YSSEL, AND JAN E. DE VRIES 108 DEOXYSPERGUALIN: MECHANISM
OF ACTION STUDIES OF A NOVEL IMMUNOSUPPRESSIVE DRUG. BY MARK A. TEPPER
123 PART III. NOVEL ANTIINFLAMMATORY STRATEGIES THE IL-IP CONVERTING
ENZYME AS A THERAPEUTIC TARGET. BY DOUGLAS K. MILLER, JIMMY R. CALAYCAY,
KEVIN T. CHAPMAN, ANDREW D. HOWARD, MATTHEW J. KOSTURA, SUSAN M.
MOLINEAUX, AND NANCY A. THORNBERRY 133 BICYCLIC IMIDAZOLES AS A NOVEL
CLASS OF CYTOKINE BIOSYNTHESIS INHIBITORS. BY J. C. LEE, A. M. BADGER,
D. E. GRISWOLD, D. DUNNINGTON, A. TRUNEH, B. VOTTA, J. R. WHITE, P. R.
YOUNG, AND P. E. BENDER 149 COORDINATE INHIBITION BY SOME ANTIOXIDANTS
OF TNFA, IL-IP, AND IL-6 PRODUCTION BY HUMAN PERIPHERAL BLOOD
MONONUCLEAR CELLS. BY ELSIE M. EUGUI, BARBARA DELUSTRO, SUSSAN ROUHAFZA,
ROBERT WILHELM, AND ANTHONY C. ALLISON 171 MYCOPHENOLIC ACID AND SOME
ANTIOXIDANTS INDUCE DIFFERENTIATION OF MONOCYTIC LINEAGE CELLS AND
AUGMENT PRODUCTION OF THE IL-1 RECEPTOR ANTAGONIST. BY RUTH V. WATERS,
DONNA WEBSTER, AND ANTHONY C. ALLISON 185 CYCLOXYGENASE GENE EXPRESSION
IN INFLAMMATION AND ANGIOGENESIS. BY TIMOTHY HLA, ARI RISTIMAKI, SUSAN
APPLEBY, AND JAVIER G. BARRIOCANAL 197 PRECLINICAL AND CLINICAL ACTIVITY
OF ZILEUTON AND A-78773. BY R. L. BELL, C. LANNI, P. E. MALO, D. W.
BROOKS, A. O. STEWART, R. HANSEN, P. RUBIN, AND G. W. CARTER 205 PART
IV. IMMUNOSUPPRESSIVE DRUGS FOR TRANSPLANTATION USE OF BREQUINAR SODIUM
FOR TRANSPLANTATION. BY DONALD V. CRAMER, FRANCES A. CHAPMAN, AND
LEONARD MAKOWKA 216 CYTIDINE POTENTIATES THE INHIBITORY EFFECT OF
BREQUINAR SODIUM ON XENO- MLR, ANTIBODY PRODUCTION, AND CONCORDANT
HAMSTER TO RAT CARDIAC XENOGRAFT SURVIVAL. BY JACKY WOO, LUIS A.
VALDIVIA, FAN PAN, SUSANNA CELLI, JOHN J. FUNG, AND ANGUS W. THOMSON 227
EFFICACY OF FK506 IN RENAL TRANSPLANTATION. BY SHIRO TAKAHARA 235
INCIDENCE OF CD4+ IL-2RA+ AND CD4+ T-CELLS IN PROGRESSIVE MULTIPLE
SCLEROSIS AND THE INFLUENCE OF SHORT-TERM (3 MONTHS) FK 506 THERAPY. BY
ANGUS W. THOMSON, JACKY WOO, BONNIE LEMSTER, WILLIAM IRISH, LINDA L.
HUANG, PATRICIA B. CARROLL, HORATIO R. RILO, KAREEM ABU-ELMAGD, AND
BENJAMIN EIDELMAN 245 FK 506 INHIBITS CYTOKINE GENE AND ADHESION
MOLECULE EXPRESSION IN PSORIATIC SKIN LESIONS. BY B. LEMSTER, H. R.
RILO, P. B. CARROLL, M. A. NALESNIK, AND A. W. THOMSON 250 INHIBITORY
EFFECT OF FK 506 ON AUTOIMMUNE THYROID DISEASE IN THE PVG RAT. BY K.
TAMURA, J. WOO, N. MURASE, M. NALESNIK, AND A. W.THOMSON 257
DEOXYSPERGUALIN: MODE OF ACTION AND CLINICAL TRIALS. BY SEIICHI SUZUKI
263 COMBINATION OF IMMUNOSUPPRESSIVE DRUGS FOR ORGAN TRANSPLANTATION. BY
TAKENORI OCHIAI, YOSHIO GUNJI, MATSUO NAGATA, AND KAICHI ISONO .. 270
IMMUNOSUPPRESSANT COMBINATIONS IN PRIMATE CARDIAC XENOGRAFTS: A REVIEW.
BY ROBERT P. MCMANUS, DANIEL P. O HAIR, RICHARD KOMOROWSKI, AND J. PAUL
SCOTT 281 PART V. CLINICAL APPLICATIONS OF IMMUNOSUPPRESSIVE AND
ANTIINFLAMMATORY DRUGS OPTIMIZING COMBINATION CHEMOTHERAPY FOR
RHEUMATOID ARTHRITIS. BY DANIEL E. FURST 285 EFFECTS OF NONSTEROIDAL
ANTIINFLAMMATORY DRUGS ON BONE LOSS IN CHRONIC INFLAMMATORY DISEASE. BY
MARJORIE K. JEFFCOAT, MICHAEL S. REDDY, LARRY W. MORELAND, AND WILLIAM
J. KOOPMAN 292 CYCLOOXYGENASE INHIBITORS VARY WIDELY IN POTENCY FOR
PREVENTING CYTOKINE- INDUCED BONE RESORPTION. BY ANTHONY C. ALLISON,
RUEI-CHEN CHIN, AND YVONNE CHENG 303 TREATMENT OF AUTOIMMUNE UVEITIS. BY
SCOTT M. WHITCUP AND ROBERT B. NUSSENBLATT... V 307 IMMUNOSUPPRESSIVE
TREATMENT OF CHRONIC LIVER DISEASE. BY E. ANTHONY JONES AND NORA VALERIA
BERGASA 319 PART VI. TREATMENT OF INSULIN-DEPENDENT DIABETES MELLITUS
MYCOPHENOLATE MOFETIL CAN PREVENT THE DEVELOPMENTOF DIABETES IN BB RATS.
BY LIMING HAO, SIU-MEI CHAN, AND KEVIN J. LAFFERTY 328 THE USE OF
NICOTINAMIDE IN THE PREVENTION OF TYPE 1 DIABETES. BY R. B. ELLIOTT, C.
C. PILCHER, A. STEWART, D. FERGUSSON, AND M. A. MCGREGOR 333 EARLY
DIAGNOSIS AND SPECIFIC TREATMENT OF INSULIN-DEPENDENT DIABETES. BY NOEL
MACLAREN, ANDREW MUIR, JANET SILVERSTEIN, YAO-HUA SONG, JIN XIONG SHE,
JEFFREY KRISCHER, MARK ATKINSON, AND DESMOND SCHATZ ; 342 LESSONS
LEARNED FROM USE OF CYCLOSPORINE FOR INSULIN-DEPENDENT DIABETES
MELLITUS: THE CASE FOR IMMUNOTHERAPY FOR INSULIN-DEPENDENT DIABETICS
HAVING RESIDUAL INSULIN SECRETION.. BY JEFFREY L. MAHON, JOHN DUPRE, AND
CALVIN R. STILLER 351 STRATEGIES IN IMMUNOTHERAPY OF INSULIN-DEPENDENT
DIABETES MELLITUS. BY JEAN-FRANCOIS BACH 364 NEW STRATEGIES FOR CLINICAL
ISLET TRANSPLANTATION: THE ROLE OF PURIFIED GRAFTS AND IMMUNOSUPPRESSIVE
THERAPY. BY PAUL F. GORES, DIXON B. KAUFMAN, AND DAVID E. R. SUTHERLAND
377 POSTER PAPERS A POWERFUL ANTIINFLAMMATORY THERAPY IS EFFECTIVE IN
THE TREATMENT OF IDIOPATHIC THROMBOCYTOPENIA. BY ADRIANA MENICHELLI AND
DOMENICO DEL PRINCIPE 390 INTERACTION OF DILTIAZEM AND RAPAMYCIN ON
SURVIVAL OF RAT CARDIAC ALLOGRAFTS. BY LOUIS DUMONT, HUIFANG CHEN,
DASHENG XU, AND PIERRE DALOZE 392 ANTIOXIDANTS INHIBIT ACTIVATION OF
TRANSCRIPTION FACTORS AND CYTOKINE GENE TRANSCRIPTION IN MONOCYTES. BY
MARIOLA ILNICKA, SIMON W. LEE, AND ELSIE M.EUGUI 396 HYDROGEN PEROXIDE
PRIMES PROMONOCYTIC U937 CELLS TO PRODUCE IL-IP. BY SIMON W. LEE AND
MARIOLA ILNICKA 399 STRUCTURE-FUNCTION ANALYSIS OF INTEGRIN-MEDIATED
CELL FUNCTIONS BY NOVEL NONPEPTIDIC CONFORMATION MIMETICS OF THE
ARG-GLY-ASP AND LEU-ASP- VAL AMINO ACID SEQUENCES. BY OFER LIDER, RAMI
HERSHKOVIZ, RONEN ALON, AND NOAM GREENSPOON 402 EFFECTS OF
CYCLOSPORINE-A AND CYCLOSPORINE-G ON ADP-STIMULATED AGGREGATION OF HUMAN
PLATELETS. BY MARIANA S. MARKELL, JULIO FERNANDEZ, ULHAS P. NAIK, YIGAL
EHRLICH, AND ELIZABETH KORNECKI 404 RELATIONSHIP OF IONIZED MAGNESIUM
AND CYCLOSPORINE LEVEL IN RENAL TRANSPLANT RECIPIENTS. BY MARIANA S.
MARKEL, BELLA T. ALTURA, YVONNE SARN, RANDALL BARBOUR, ELI A. FRIEDMAN,
AND BURTON M. ALTURA 408 STUDIES ON THE INTERACTION OF THE
IMMUNOSUPPRESSANT 15-DEOXYSPERGUALIN WITH HEAT SHOCK PROTEINS. BY STEVEN
G. NADLER, JEFFREY CLEAVELAND, MARK A. TEPPER, CHRISTOPHER WALSH, AND
KARI NADEAU 412 4-THIAZOLIDINONES, POTENT ANTIOXIDANTS, AS
ANTIINFLAMMATORY AGENTS. BY J. A. PANETTA, J. K. SHADLE, M. L. PHILLIPS,
D. N. BENSLAY, AND P. P. K. HO... 415 EFFECTS OF METHYLPREDNISOLONE
ADMINISTRATION ON LYMPHOCYTE LECAM-1, CD44, AND LFA-1 EXPRESSION:
IMPLICATIONS FOR STEROID-INDUCED LYMPHOPENIA. BY ROBERT SACKSTEIN 416
CMT/NSAID COMBINATION INCREASES BONE CMT UPTAKE AND INHIBITS BONE
RESORPTION. BY N. RAMAMURTHY, M. LEUNG, S. MOAK, R. GREENWALD, AND L.
GOLUB 420 INDEX OF CONTRIBUTORS : 423
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dewey-tens | 610 - Medicine and health 500 - Natural sciences and mathematics |
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subject_GND | (DE-588)4123144-2 (DE-588)4161389-2 (DE-588)1071861417 |
title | Immunosuppressive and antiinflammatory drugs [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida] |
title_auth | Immunosuppressive and antiinflammatory drugs [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida] |
title_exact_search | Immunosuppressive and antiinflammatory drugs [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida] |
title_full | Immunosuppressive and antiinflammatory drugs [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida] ed. by Anthony C. Allison ... |
title_fullStr | Immunosuppressive and antiinflammatory drugs [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida] ed. by Anthony C. Allison ... |
title_full_unstemmed | Immunosuppressive and antiinflammatory drugs [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida] ed. by Anthony C. Allison ... |
title_short | Immunosuppressive and antiinflammatory drugs |
title_sort | immunosuppressive and antiinflammatory drugs this volume is the result of a conference held on april 12 15 1993 in orlando florida |
title_sub | [this volume is the result of a conference ... held on April 12 - 15, 1993 in Orlando, Florida] |
topic | Antiphlogistikum (DE-588)4123144-2 gnd Immunsuppressivum (DE-588)4161389-2 gnd |
topic_facet | Antiphlogistikum Immunsuppressivum Konferenzschrift 1993 Orlando Fla. |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006351694&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV002532608 |
work_keys_str_mv | AT allisonanthonyc immunosuppressiveandantiinflammatorydrugsthisvolumeistheresultofaconferenceheldonapril12151993inorlandoflorida |