International Bilirubin Workshop 1992: Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste
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| Format: | Tagungsbericht Buch |
| Sprache: | Undetermined |
| Veröffentlicht: |
Trieste
Univ.
1992
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 89 Bl. graph. Darst. |
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Datensatz im Suchindex
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| adam_text | INTERNATIONAL BILIRUBIN WORKSHOP 1992
DAY 1 April 9, 1992 : Chemistry. Physical Chemistry and Conjugation
SESSION I: CHEMISTRY AND PHYSICAL CHEMISTRY OF BILIRUBIN
Chairman. David Lightner. Reno. NV. USA
8.20 8.30 Welcome Introduction (C. Tiribelli, Italy)
8.30 9.05 Ionization, Self Association and Solubility of Unconjugated Bilirubin and
its Interactions with Calcium, determined by Solvent Partition from
Chloroform (J.Donald Ostrow et al., Chicago, IL, USA)
9.05 9.40 Physical Chemistry of Bilirubin and its Relationship to Bilirubin Uptake
(Richard P. Wennberg, Davis, CA, USA)
9.40 10.15 Antioxidant Properties of Bilirubin (John L. Gollan, Boston, MA, USA)
10.15 10.45 Coffee Break
Chairman: Heinz Falk. Linz. Austria
10.45 11.20 Chemistry of Bilirubin Analogues (William E. Kurtin et al., San Antonio, TX,
USA)
11.20 11.55 Metabolism and Excretion of Bilirubin Analogues (Antony F. McDonagh et
al., San Francisco, CA, USA)
11.55 13.00 Discussion
13.00 14.15 Lunch and Viewing of Posters
SESSION H: CONJUGATION
Chairman: John Gollan. Boston MA. USA
14.15 14.50 Expression, Regulation and Genetics of human Bilirubin UDP
Glucuronosyltransferase (Brian Burchell et al., Dundee, Scotland)
14.50 15.25 Bilirubin UDP Glucuronosyltransferase: Expression in normal Liver and in
inherited Deficiency. (Jayanta Roy Chowdhury et al., Bronx, NY, USA)
15.25 16.00 Transmembrane Transport of UDP Glucuronic Acid in Rat Liver Microsomes.
(N. Blankaert et al., Leuven, Belgium)
16.00 16.40 General Discussion
16.40 17.10 Coffee Break
; Chairman. Norbert Blankaert. Leuven. Belgium
17.10 18.30 Poster Discussion I Bilirubin Chemistry and Toxicity; Bilirubin
Metabolism in Congenital Jaundice
17.10 17.20 Micellar electrokinetic capillar chromatography of bilirubin in sodium
taurocholate solution: Determination of ionization constants. W.E: Kurtin,
M.M. Bushey and R.E. Kibbey, San Antonio (USA) (P14)
17.20 17.30 Copper forms black bilirubinate salts related to the fqrmatiort of free radicals
and causes alteration of the pyrrole rings and tetrapyfrole structure. W.H. Li,
X.B. Tong, R.D. Soloway, W.J. Zhou, S.F. Weng, G.R. Shen, D.F. Xu, D.
Taylor, N.K. Hong, N. Hirakawa, R.S. Crowther and J.G. Wu. Beijing
(PRC) and Galweston (USA). (P13)
17.30 17.40 On the chemical oxidation of biladienes ac and 1,19 bilindiones. J.M. Ribo,
F.R. Trull, C. Acero,*R. Soler, Barcelona (E) (P18)
17.40 17.50 Study of non aggregated bilirubin interaction on human erythrocytes.
Antihemolytic and crenation effects. R. Silva and D. Brites, Lisbon (P) (P20)
17.50 18.00 In vivo role of bilirubin in neonatal antioxidant defenses. P.A. Dennery, A.F.
McDonagh, D.K. Stevenson, Stanford and San Francisco (USA) (P5)
18.00 18.10 Effect of antioxidants on hepatic lipid peroxidation and bilirubin metabolism in
Gunn rats. M. Joshi, T. Hallinan and B. Billing, London (UK) (Pll)
18.10 18.20 Intestinal excretion of bilirubin in Crigler Najjar syndrome and Gunn rats. P.
Kotal, C. van der Veere, R. Ottenhoff, M. Sinaasappel, R.P.J. Oude Elferink,
J. Fevery, P.L.M. Jansen, Prague (TCH), Amsterdam and Rotterdam (NL),
Leuven (B) (P12)
18.20 18.30 Decreased fluidity, cytoskeleton breakdown, and hemolysis of human
erythrocyte induced by bilirubin, under aggregating conditions. D. Brites and
R. Silva, Lisbon (P) (P2)
DAY 2 April 10, 1992 : Transpon and Metabolism
SESSIONIH: TRANSPORT: CARRIER PROTEINS
Chairman: Claudio Tiribelli. Trieste
8.15 8.50 Pitfalls in Studies of Carrier Proteins (Gehard Kurz, Freiburg, Germany)
8.50 9.25 Studies of Oléate Uptake Kinetics in perfused Liver, Hepatocytes and 3T3 L1
Cells indicate that the Plasma Membrane Fatty Acid Binding Protein mediates
a specific, facilitated Uptake Process (Paul D. Berk, New York, NY, USA)
9.25 10.00 The Membrane Fatty Acid Uptake System: A controversial Issue (Wolfgang
Stremmel, Dusseldorf, Germany)
10.00 10.20 CoffeeBreak
10.20 10.55 Bilitranslocase (Gian Luigi Sottocasa, Trieste, Italy)
10.55 11.30 Chloride dependent Hepatocyte Organic Anión Transpon (Alian W. Wolkoff,
Bronx, NY, USA)
11.30 12.05 Bilirubin Conjugates as Substrates for a Canalicular Multispecific Organic
Anión Transporter in the Liver (Peter L.M. Jansen, Amsterdam, The
Netherlands)
12.05 13.05 General Discussion
13.05 14.20 Lunch and Viewing of Posters
SESSION IV: REGULATION OF HEPATIC UPTAKE
Chairman: Paul D. Berk. New York. NY. USA
14.20 14.55 A Balanced View of Hepatic Organic Anión Transpon (Richard A.
Weisiger, San Francisco, CA, USA)
14.55 15.30 Are Carrier Proteins necessary for Uptake of Bilirubin? (David Zakim et al.,
New York, NY, USA)
15.30 16.05 Mechanisms in Regulation of Hepatic Uptake of Organic Anions (Claudio
Tiribelli et al., Trieste, Italy)
16.05 16.45 General Discussion
16.45 17.10 CoffeeBreak
j
Chairman. Peter L.M. Jansen. Amsterdam. The Netherlands
17.10 18.30 Poster Discussion II Bilirubin Transport and Conjugation
17.10 17.20 Importance of carboxyles for the excretion of bilirubin. M. Jirsa, P. Kotal, M.
Jirsa Jr., Z. Blehova, Prague (TCH) (P10)
17.20 17.30 The effects of parenteral nutrition on bilirubin metabolism in the rat. J.
Gonzales, J. Garcia Vielba, F. Garcia Diez, P.S. Collado, and J. Culebras,
J^eon (E) (P8)
17.30 17.40 Reinterpretation of initial rate steady state uptake of natural fatty acids into
isolated cells. K.P.M. Heirwegh and E.M.F. Cresens, J^euven (B) (P9)
17.40 17.50 Dependance of canalicular excretion of organic anions on extracellular
potassium concentration. C. Veith, T. Thalhammer, V. Stapf and J. Graf,
Vienna (A) (P23)
17.50 18.00 Sequence of intron exon junction of the human B UGT gene, and identification
of mutation in Crigler Najjar syndrome type 1. P.J. Bosma, N. Roy
Chowdhury, B. Goldhoorn, R.P.J. Oude Elferink, P.L.M. Jansen, and J. Roy
Chowdhury, Amsterdam (NL), Bronx (USA) (PI)
18.00 18.10 Potent and competitive inhibitors of bilirubin UDP glucuronosyltransferase. M.
Said, E. Battaglia, J.C. Ziegler, T. Pillot, S. Fournel Gigleux, J. Magdalou,
A. Cartier and G. Siest, Nancy (F) (P19)
18.10 18.20 Enhancement of intestinal bilirubin UDP glucuronyltransferase activity by
modification of microsomal lipid composition. E.S. Pozzi, A. Mottino and
E.A. Rodriguez Garay, Rosario (RA) (P17)
20.00 Gala Dinner
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DAY 3 April 11 : Defects, Animal Models and Treatment
SESSION V: ALTERNATE PATHWAYS OF BILIRUBIN METABOLISM
Chairman J. Donald Ostrow. Chicago. IL. USA
8.15 8.50 The Role of Cytochrome P 450 in the Alternate Pathways of Bilirubin
Metabolism in Congenitally Jaundiced Gunn Rats and Infants with the Crigler
j Najjar Syndrome Type I. (Jaime Kapitulnik, Jerusalem, Israel)
! 8.50 9.25 Intestinal Excretion of Unconjugated Bilirubin and its Conversion to
Urobilinogen is a Determinant of serum Bilirubin in Fasting
Hyperbilirubinemia of the Gunn Rat (Johan Fevery et al., Leuven, Belgium)
9.25. 10.00 Renal Metabolism of Bilirubin (M. Monica Elias, Rosario, Argentina)
10.00 10.40 General Discussion
10.40 11.05 Coffee Break
SESSION VI: UNCONJUGATED HYPERBILIRUBINEMIA IN NEONATES
Chairman: Johan Fevery. Leuven. Belgium
11.05 11.40 Bilirubin Toxicity: Mechanisms and Assessment (Dag Bratlid, Oslo, Norway)
11.40 12.15 New Therapies of Neonatal Jaundice (David K. Stevenson, Stanford, CA,
USA)
12.15 12.45 General Discussion
12.45 Meeting ends
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| spelling | International Bilirubin Workshop 2 1992 Triest Verfasser (DE-588)1226123-3 aut International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste Trieste Univ. 1992 89 Bl. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Bilirubin (DE-588)4145513-7 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1992 Triest gnd-content Bilirubin (DE-588)4145513-7 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005896246&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste Bilirubin (DE-588)4145513-7 gnd |
| subject_GND | (DE-588)4145513-7 (DE-588)1071861417 |
| title | International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste |
| title_auth | International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste |
| title_exact_search | International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste |
| title_full | International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste |
| title_fullStr | International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste |
| title_full_unstemmed | International Bilirubin Workshop 1992 Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste |
| title_short | International Bilirubin Workshop 1992 |
| title_sort | international bilirubin workshop 1992 trieste april 9 11 1992 centro congressi stazione marittima trieste |
| title_sub | Trieste, April 9 - 11, 1992, Centro Congressi, Stazione Marittima, Trieste |
| topic | Bilirubin (DE-588)4145513-7 gnd |
| topic_facet | Bilirubin Konferenzschrift 1992 Triest |
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