Peripheral benzodiazepine receptors:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London [u.a.]
Acad. Press
1993
|
| Schriftenreihe: | Neuroscience perspectives
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 281 S. Ill., graph. Darst. |
| ISBN: | 0122826302 |
Internformat
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| 490 | 0 | |a Neuroscience perspectives | |
| 650 | 4 | |a Benzodiazepines |x Receptors | |
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| 650 | 4 | |a Benzodiazepines |x pharmacology | |
| 650 | 4 | |a Ligands | |
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| 650 | 4 | |a Neural receptors | |
| 650 | 4 | |a Receptors, GABA-A |x physiology | |
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Datensatz im Suchindex
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| adam_text | * * ! PERIPHERAL BENZODIAZEPINE RECEPTORS EDITED BY E. GIESEN-CROUSE
INSTITUT DE RECHERCHES SERVIER SURESNES, FRANCE ACADEMIC PRESS HARCOURT
BRACE JOVANOVICH, PUBLISHERS LONDON SAN DIEGO NEW YORK BOSTON SYDNEY
TOKYO TORONTO CONTENTS SERIES PREFACE PREFACE XIII BIOCHEMICAL AND
CHEMICAL CHARACTERISTICS OF THE 1 MITOCHONDRIAL BENZODIAZEPINE RECEPTOR
AND ITS LIGANDS 1 MOLECULAR PROPERTIES OF MITOCHONDRIAL BENZODIAZEPINE
RECEPTORS 3 A. L. PAROLA AND H. I. YAMAMURA 1.1 INTRODUCTION 4 1.2
CHEMICAL AND ENZYMATIC INHIBITION OF MBR 5 1.3 MBR IRREVERSIBLE LIGANDS
10 1.4 MBR SOLUBILIZATION AND PURIFICATION 13 1.5 MOLECULAR BIOLOGY OF
THE MBR 16 1.6 CONCLUSIONS 21 REFERENCES 22 2 BINDING CHARACTERISTICS OF
THE RECEPTOR AND COUPLING TO 27 TRANSPORT PROTEINS L. HERTZ 2.1
INTRODUCTION 27 2.2 CELL AND ORGAN DISTRIBUTION 28 2.3 SUBCELLULAR
DISTRIBUTION 33 2.4 ASSOCIATION AND DISSOCIATION KINETICS 36 2.5
PHARMACOLOGICAL CHARACTERISTICS WITHIN THE GROUP OF BENZODIAZEPINES 38
2.6 EFFECTS OF BENZODIAZEPINES ON BINDING SITES FOR OTHER DRUGS AND
EFFECTS OF OTHER AGENTS ON THE MITOCHONDRIAL BINDING SITE 41 2.7 EFFECTS
OF MITOCHONDRIAL BENZODIAZEPINE LIGANDS 45 2.8 CONCLUDING REMARKS 49
ACKNOWLEDGEMENTS 51 REFERENCES 51 3 ENDOGENOUS AND SYNTHETIC LIGANDS OF
MITOCHONDRIAL 59 BENZODIAZEPINE RECEPTORS: STRUCTURE-AFFINITY
RELATIONSHIPS J. J. BOURGUIGNON 3.1 INTRODUCTION 59 3.2 POTENTIAL
ENDOGENOUS LIGANDS OF MBR 60 3.3 BENZODIAZEPINES AND STRUCTURALLY
RELATED COMPOUNDS 61 3.4 3.5 3.6 3.7 3.8 3.9 3.10 CONTENTS 2-PHENYL
QUINOLINE CARBOXAMIDES (PK 11195 SERIES) AND RELATED COMPOUNDS
IMIDAZO[L,2-A]PYRIDINE-3-ACETAMIDES (ALPIDEM SERIES)
3-ACYL-4-AMINOACETAMIDE QUINOLINES AND OTHER RELATED SR COMPOUNDS
IMIDAZO[L,5-C]QUINAZOLINONE-6-ACETAMIDES (NCS 1000 SERIES) PYRIDAZINE
DERIVATIVES OTHER PHARMACOLOGICAL REAGENTS DISCUSSION ACKNOWLEDGEMENTS
REFERENCES 66 69 70 72 75 78 79 81 82 PHARMACOLOGICAL EFFECTS OF
PERIPHERALLY ACTING BENZODIAZEPINES 87 4 THE ROLE OF MITOCHONDRIAL
BENZODIAZEPINE RECEPTORS IN 89 STEROIDOGENESIS K. E. KRUEGER AND A.
PAPADOPOULOS 4.1 INTRODUCTION 89 4.2 FUNCTIONAL CUES GAINED FROM TISSUE
DISTRIBUTION 90 4.3 BIOCHEMICAL AND CELL BIOLOGICAL BASIS OFSTEROID
BIOSYNTHESIS 91 4.4 REGULATION OF STEROIDOGENESIS MEDIATED BY MBR 92 4.5
RELATIONSHIP OF MBR STRUCTURE TO STEROIDOGENESIS 102 4.6 PHARMACOLOGICAL
SIGNIFICANCE IN THE BRAIN 102 4.7 POSSIBLE CORRELATIONS WITH OTHER
CELLULAR ACTIVITIES 103 REFERENCES 105 5 EFFECTS OF PERIPHERALLY ACTING
BENZODIAZEPINES ON CELL GROWTH 111 AND DIFFERENTIATION V. SAANO 5.1
INTRODUCTION 111 5.2 BENZODIAZEPINE RECEPTORS 112 5.3 EFFECTS OF
BENZODIAZEPINES ON CELL CYCLE AND DIFFERENTIATION: MEDIATION VIA MBR?
114 5.4 ACTIONS OF PUTATIVE ENDOGENOUS MITOCHONDRIAL BENZODIAZEPINE
RECEPTOR LIGANDS: DIRECT EFFECTS AND POTENTIATION OF OTHER EFFECTORS 117
5.5 CONCLUSIONS 118 ACKNOWLEDGEMENTS 118 REFERENCES 119 6
IMMUNOMODULATING EFFECTS OF PERIPHERALLY ACTING 125 BENZODIAZEPINES M.
PAWLIKOWSKI 6.1 INTRODUCTION 125 6.2 EFFECTS OF MBR LIGANDS ON
PROLIFERATION OF LYMPHOID CELLS IN VITRO 126 6.3 IN VITRO EFFECTS OF
BENZODIAZEPINES ON IMMUNE-CELL FUNCTIONS 129 6.4 IN VIVO
IMMUNOMODULATORY ACTIONS OF BENZODIAZEPINES AND OTHER MBR LIGANDS 130
6.5 CONCLUDING REMARKS 132 REFERENCES 133 MODULATION OF MEMORY
CONSOLIDATION BY CENTRAL AND 137 PERIPHERAL BENZODIAZEPINE RECEPTOR
LIGANDS J. H. MEDINA AND I. IZQUIERDO 7.1 INTRODUCTION 137 7.2
BENZODIAZEPINES AND MEMORY MODULATION 138 7.3 CONCLUSION 143 REFERENCES
144 MITOCHONDRIAL BENZODIAZEPINE RECEPTORS AND SMOOTH MUSCLE 149
REACTIVITY G. MARANO 8.1 INTRODUCTION 149 8.2 FUNCTIONAL ROLE OF MBR 149
8.3 CONCLUSION 151 REFERENCES 151 CARDIOVASCULAR ACTIONS OF PERIPHERAL
BENZODIAZEPINES 153 G. T. BOLGER 9.1 INTRODUCTION 153 9.2 CARDIOVASCULAR
MITOCHONDRIAL BENZODIAZEPINE RECEPTORS 154 9.3 CARDIOVASCULAR ACTIONS OF
LIGANDS ACTING AT MBR 157 9.4 FUNCTIONAL SITES OF INTERACTION FOR MBR
LIGANDS 159 9.5 SUMMARY 161 REFERENCES 162 MODULATION OF RECEPTOR
NUMBERS IN RESPONSE TO 169 PATHOPHYSIOLOGICAL SITUATIONS 10 EFFECT OF
CHANGES IN TISSUE CONCENTRATIONS OF PUTATIVE 171 ENDOGENOUS LIGANDS ON
MITOCHONDRIAL BENZODIAZEPINE RECEPTORS EX VIVO T. MENNINI 10.1
INTRODUCTION 171 10.2 MBR INTERACTION WITH PORPHYRINS 172 10.3 MBR
INTERACTION WITH DIAZEPAM BINDING INHIBITOR 177 10.4 CONCLUSION 183
REFERENCES 184 CONTENTS 11 MODIFICATIONS OF MITOCHONDRIAL BENZODIAZEPINE
RECEPTOR 187 NUMBERS IN STRESSFUL SITUATIONS R. H. DODD AND M. LENFANT
11.1 INTRODUCTION 188 11.2 STRESSFUL SITUATIONS WHICH CAUSE A DECREASE
IN MBR DENSITIES 189 11.3 STRESSFUL SITUATIONS WHICH CAUSE AN INCREASE
IN MBR DENSITIES 193 11.4 STRESS, IMMUNE FUNCTIONS AND MBR 197 11.5
CONCLUSION 200 REFERENCES 201 12 PATHOPHYSIOLOGICAL AND ENDOCRINOLOGICAL
ASPECTS OF 209 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTORS M. GAVISH, S.
BAR-AMI AND R. WEIZMAN 12.1 INTRODUCTION 210 12.2 MBR AND CANCER 210
12.3 THE INVOLVEMENT OF MBR IN NEUROPSYCHIATRIC DISORDERS 211 12.4
ENDOCRINOLOGICAL ASPECTS OF MBR 219 12.5 OTHER DISEASES 226
ACKNOWLEDGEMENT 227 REFERENCES 227 13 MITOCHONDRIAL BENZODIAZEPINE
RECEPTOR LIGANDS AS INDICATORS OF 235 DAMAGE IN THE CNS: THEIR
APPLICATION IN POSITRON EMISSION TOMOGRAPHY R. MYERS 13.1 INTRODUCTION
236 13.2 STUDIES OF LESIONED BRAIN TISSUE 237 13.3 THE CELL-TYPE
LOCALIZATION OF MITOCHONDRIAL BENZODIAZEPINE RECEPTORS 244 13.4 POSITRON
EMISSION TOMOGRAPHY OF THE HUMAN CNS USING MBR LIGANDS 252 13.5 THE
FUTURE POTENTIAL OF MBR IMAGING 261 13.6 SUMMARY AND CONCLUSIONS 266
ACKNOWLEDGEMENTS 267 REFERENCES 267 INDEX 275 COLOUR PLATES 1-3
REFERRING TO CHAPTERS 3 AND 13 RESPECTIVELY APPEAR BETWEEN PAGES 242-243
VIII
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| indexdate | 2024-07-09T17:18:12Z |
| institution | BVB |
| isbn | 0122826302 |
| language | English |
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| physical | XIV, 281 S. Ill., graph. Darst. |
| publishDate | 1993 |
| publishDateSearch | 1993 |
| publishDateSort | 1993 |
| publisher | Acad. Press |
| record_format | marc |
| series2 | Neuroscience perspectives |
| spelling | Peripheral benzodiazepine receptors ed. by E. Giesen-Crouse London [u.a.] Acad. Press 1993 XIV, 281 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neuroscience perspectives Benzodiazepines Receptors Benzodiazepines metabolism Benzodiazepines pharmacology Ligands Nerves, Peripheral Effect of drugs on Neural receptors Receptors, GABA-A physiology Benzodiazepine (DE-588)4005552-8 gnd rswk-swf Neuropharmakologie (DE-588)4041896-0 gnd rswk-swf Benzodiazepinrezeptor (DE-588)4255002-6 gnd rswk-swf Benzodiazepinrezeptor (DE-588)4255002-6 s DE-604 Benzodiazepine (DE-588)4005552-8 s Neuropharmakologie (DE-588)4041896-0 s Giesen-Crouse, Eva Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005494521&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Peripheral benzodiazepine receptors Benzodiazepines Receptors Benzodiazepines metabolism Benzodiazepines pharmacology Ligands Nerves, Peripheral Effect of drugs on Neural receptors Receptors, GABA-A physiology Benzodiazepine (DE-588)4005552-8 gnd Neuropharmakologie (DE-588)4041896-0 gnd Benzodiazepinrezeptor (DE-588)4255002-6 gnd |
| subject_GND | (DE-588)4005552-8 (DE-588)4041896-0 (DE-588)4255002-6 |
| title | Peripheral benzodiazepine receptors |
| title_auth | Peripheral benzodiazepine receptors |
| title_exact_search | Peripheral benzodiazepine receptors |
| title_full | Peripheral benzodiazepine receptors ed. by E. Giesen-Crouse |
| title_fullStr | Peripheral benzodiazepine receptors ed. by E. Giesen-Crouse |
| title_full_unstemmed | Peripheral benzodiazepine receptors ed. by E. Giesen-Crouse |
| title_short | Peripheral benzodiazepine receptors |
| title_sort | peripheral benzodiazepine receptors |
| topic | Benzodiazepines Receptors Benzodiazepines metabolism Benzodiazepines pharmacology Ligands Nerves, Peripheral Effect of drugs on Neural receptors Receptors, GABA-A physiology Benzodiazepine (DE-588)4005552-8 gnd Neuropharmakologie (DE-588)4041896-0 gnd Benzodiazepinrezeptor (DE-588)4255002-6 gnd |
| topic_facet | Benzodiazepines Receptors Benzodiazepines metabolism Benzodiazepines pharmacology Ligands Nerves, Peripheral Effect of drugs on Neural receptors Receptors, GABA-A physiology Benzodiazepine Neuropharmakologie Benzodiazepinrezeptor |
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