Guidelines for drug trials in memory disorders:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York u.a.
Raven Press
1993
|
| Schriftenreihe: | Aging
39 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XV, 365 S. Ill., graph. Darst. |
| ISBN: | 0781701082 |
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Datensatz im Suchindex
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| adam_text | R 7 / AGING VOLUME 39 GUIDELINES FOR DRUG TRIALS IN MEMORY DISORDERS
EDITORS NICOLA CANAL, M.D. DEPARTMENT OF NEUROLOGY UNIVERSITY OF MILAN
ISTITUTO SCIENTIFICO H. SAN RAFFAELE MILAN, ITALY GUY MCKHANN, M.D.
JOHNS HOPKINS SCHOOL OF MEDICINE DEPARTMENT OF NEUROLOGY BALTIMORE,
MARYLAND VLADIMIR C. HACHINSKI, M.D., D.SC.MED. DEPARTMENT OF CLINICAL
NEUROLOGICAL SCIENCES UNIVERSITY HOSPITAL LONDON, ONTARIO, CANADA
MASSIMO FRANCESCHI, M.D. DEPARTMENT OF NEUROLOGY UNIVERSITY OF MILAN
ISTITUTO SCIENTIFICO H. SAN RAFFAELE MILAN, ITALY RAVEN PRESS NEW YORK
CONTENTS ETHICAL PROBLEMS 1. INFORMED CONSENT IN THE CONTEXT OF CLINICAL
PRACTICE AND SCIENTIFIC INQUIRY 1 M. ROTH 2. THE INFORMED CONSENT 7 R.
J. JOYNT AND J. GREENLAW 3. DISCUSSION 13 DIFFERENT STRATEGIES FOR
MEMORY DISORDERS 4. DEGENERATIVE DISORDERS 19 N. CANAL 5. VASCULAR
DISORDERS 25 V. C. HACHINSKI 6. TRAUMATIC BRAIN INJURY 31 A. M. SALAZAR
AND J. H. GRAF MAN 7. DISCUSSION 51 MINIMAL PHARMACOLOGIC REQUIREMENTS
FOR DRUG SELECTION 8. INTRODUCTION 63 C. G. GOTTFRIES 9. SELECTION OF
DRUGS FOR THE TREATMENT OF MEMORY DISORDERS 71 D. A. DRACHMAN AND J. M.
SWEARER 10. PHASE I STUDIES 87 M. LADER AND V. CURRAN 11. DISCUSSION 97
STUDY DESIGN 12. STATISTICAL ISSUES IN DESIGNING CLINICAL TRIALS IN
MEMORY DISORDERS 99 F. GRIGOLETTO IX JC CONTENTS 13. END POINTS,
DURATION, AND SIDE EFFECTS 115 G. K. WILCOCK 14. PROBLEMS AND PITFALLS
OF SOME CLINICAL TRIALS IN MEMORY DISORDERS 125 A. LIPPI 15. PLACEBOS
AND OTHER BIASES IN CLINICAL TRIALS IN DEMENTIA 135 A. D. KORCZYN 16.
SPECIAL CONSIDERATIONS IN THE DESIGN OF ALZHEIMER DISEASE TRIALS 143 L.
J. THAI 17. DISCUSSION 151 DRUG TRIALS FOR MEMORY DISORDERS: THE WHO
PERSPECTIVE 18. INTRODUCTION 159 J. M. BERTOLOTE 19. DISCUSSION 165
PATIENT SELECTION GUIDELINES 20. INTRODUCTION 169 B. REISBERG 21.
DIAGNOSTIC ASSESSMENTS AND CRITERIA FOR MEMORY DISORDERS IN CLINICAL
DRUG TRIALS . . . . 191 T. ERKINJUNTTI, R. SULKAVA, AND V. C.
HACHINSKI 22. SELECTION AND EVALUATION OF EARLY CASES OF ALZHEIMER
DISEASE 213 R. LEVY 23. THE CAMBRIDGE MENTAL DISORDERS OF THE ELDERLY
EXAMINATION, WITH SPECIAL REFERENCE TO ITS USE IN THE DIAGNOSIS OF
MILD OR EARLY DEMENTIA 219 M. ROTH 24. SELECTION METHODOLOGIES 235
S. H. FERRIS 25. DISCUSSION 243 CONTENTS XI ASSESSMENT OF EFFICACY 26.
ASSESSMENT OF DRUG EFFECTS IN AGE-ASSOCIATED MEMORY IMPAIRMENT 245 T. H.
CROOK 27. CLINICAL ASSESSMENT OF EFFICACY FOR DRUG TRIALS IN MEMORY
DISORDERS 251 M. SANO AND R. MAYEUX 28. NEUROPSYCHOLOGICAL ASSESSMENT IN
PATIENTS WITH MEMORY IMPAIRMENT AND WITH ALZHEIMER DISEASE 265 F.
BOILER, M. PANISSET, AND J. SAXTON 29. ISSUES OF DESIGN AND ASSESSMENT
MAY AFFECT THE DETERMINATION OF EFFICACY IN CHOLINERGIC TREATMENT
STUDIES IN ALZHEIMER DISEASE : . . 277 B. A. LAWLOR AND B. M. DAVIS 30.
FUNCTIONAL METABOLIC ASSESSMENT USING POSITRON EMISSION TOMOGRAPHY 287
J. C. BARON 31. NEUROPHYSIOLOGICAL ASSESSMENT OF EFFICACY IN DRUG TRIALS
WITH MEMORY DISORDERS 303 B. SALETU 32. NONCOGNITIVE SYMPTOMS IN
DEMENTIA 333 P. J. WHITEHOUSE 33. DISCUSSION 341 34. CONCLUDING REMARKS
349 R. J. JOYNT SUBJECT INDEX 351
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| spelling | Guidelines for drug trials in memory disorders eds.: Nicola Canal ... New York u.a. Raven Press 1993 XV, 365 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Aging 39 Essais cliniques comme sujet - Méthode - Congrès comme sujet Geheugenstoornissen gtt Klinische farmacologie gtt Mémoire, Troubles de la - Chimiothérapie - Tests - Méthodologie Neuropsychopharmacologie - Méthodologie Nootropiques - Essais - Méthodologie Trouble mémoire - Pharmacothérapie - Congrès Clinical Trials as Topic methods Congresses Memory Disorders drug therapy Congresses Memory disorders Chemotherapy Testing Methodology Neuropsychopharmacology Methodology Nootropic agents Testing Methodology Chemotherapie (DE-588)4127083-6 gnd rswk-swf Nootropikum (DE-588)4202974-0 gnd rswk-swf Gedächtnisstörung (DE-588)4156190-9 gnd rswk-swf Pharmakologie (DE-588)4045687-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift gnd-content Gedächtnisstörung (DE-588)4156190-9 s Chemotherapie (DE-588)4127083-6 s DE-604 Nootropikum (DE-588)4202974-0 s Pharmakologie (DE-588)4045687-0 s Canal, Nicola Sonstige oth Aging 39 (DE-604)BV000001127 39 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005494428&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Guidelines for drug trials in memory disorders Aging Essais cliniques comme sujet - Méthode - Congrès comme sujet Geheugenstoornissen gtt Klinische farmacologie gtt Mémoire, Troubles de la - Chimiothérapie - Tests - Méthodologie Neuropsychopharmacologie - Méthodologie Nootropiques - Essais - Méthodologie Trouble mémoire - Pharmacothérapie - Congrès Clinical Trials as Topic methods Congresses Memory Disorders drug therapy Congresses Memory disorders Chemotherapy Testing Methodology Neuropsychopharmacology Methodology Nootropic agents Testing Methodology Chemotherapie (DE-588)4127083-6 gnd Nootropikum (DE-588)4202974-0 gnd Gedächtnisstörung (DE-588)4156190-9 gnd Pharmakologie (DE-588)4045687-0 gnd |
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| title | Guidelines for drug trials in memory disorders |
| title_auth | Guidelines for drug trials in memory disorders |
| title_exact_search | Guidelines for drug trials in memory disorders |
| title_full | Guidelines for drug trials in memory disorders eds.: Nicola Canal ... |
| title_fullStr | Guidelines for drug trials in memory disorders eds.: Nicola Canal ... |
| title_full_unstemmed | Guidelines for drug trials in memory disorders eds.: Nicola Canal ... |
| title_short | Guidelines for drug trials in memory disorders |
| title_sort | guidelines for drug trials in memory disorders |
| topic | Essais cliniques comme sujet - Méthode - Congrès comme sujet Geheugenstoornissen gtt Klinische farmacologie gtt Mémoire, Troubles de la - Chimiothérapie - Tests - Méthodologie Neuropsychopharmacologie - Méthodologie Nootropiques - Essais - Méthodologie Trouble mémoire - Pharmacothérapie - Congrès Clinical Trials as Topic methods Congresses Memory Disorders drug therapy Congresses Memory disorders Chemotherapy Testing Methodology Neuropsychopharmacology Methodology Nootropic agents Testing Methodology Chemotherapie (DE-588)4127083-6 gnd Nootropikum (DE-588)4202974-0 gnd Gedächtnisstörung (DE-588)4156190-9 gnd Pharmakologie (DE-588)4045687-0 gnd |
| topic_facet | Essais cliniques comme sujet - Méthode - Congrès comme sujet Geheugenstoornissen Klinische farmacologie Mémoire, Troubles de la - Chimiothérapie - Tests - Méthodologie Neuropsychopharmacologie - Méthodologie Nootropiques - Essais - Méthodologie Trouble mémoire - Pharmacothérapie - Congrès Clinical Trials as Topic methods Congresses Memory Disorders drug therapy Congresses Memory disorders Chemotherapy Testing Methodology Neuropsychopharmacology Methodology Nootropic agents Testing Methodology Chemotherapie Nootropikum Gedächtnisstörung Pharmakologie Konferenzschrift |
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