Shikimic acid: metabolism and metabolites
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Chichester u.a.
Wiley
1993
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 387 S. Ill. |
| ISBN: | 0471939994 |
Internformat
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Datensatz im Suchindex
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| adam_text | SHIKIMIC ACID METABOLISM AND METABOLITES EDWIN HASLAM UNIVERSITY OF
SHEFFIELD, SHEFFIELD, UK JOHN WILEY & SONS CHICHESTER * NEW YORK *
BRISBANE * TORONTO * SINGAPORE CONTENTS PREFACE XI CHAPTER 1
INTRODUCTION, COMMENTARY AND OVERVIEW 1 1.1 BIOSYNTHESIS AND THE
SHIKIMATE PATHWAY 1 1.2 EVOLUTION AND THE SHIKIMATE PATHWAY 5 1.2.1 THE
METABOLIC COSTS OF AROMATIC A-AMINO ACID SYNTHESIS 5 1.2.2
MULTIFUNCTIONAL ENZYMES*THE AROM COMPLEX 6 1.3 DEVELOPMENTS IN
METHODOLOGY 9 1.3.1 GENETIC ENGINEERING 10 1.3.2 ORGANIC CHEMICAL
SYNTHESIS 13 CHAPTER 2 CHEMISTRY OF INTERMEDIATES IN THE COMMON PATHWAY
17 2.1 D-ERYTHROSE-4-PHOSPHATE 17 2.2 PHOSPHOENOLPYRUVATE (PEP) 20 2.3
3-DEOXY-D-ARAFRINO-HEPTULOSONIC ACID 7-PHOSPHATE (DAHP) 26 2.4
3-DEHYDROQUINIC ACID 35 2.5 3-DEHYDROSHIKIMIC ACID 38 2.6 SHIKIMIC ACID
39 2.6.1 DISCOVERY, ISOLATION AND PROPERTIES 39 2.6.2 SYNTHESIS 50 2.7
SHIKIMIC ACID 3-PHOSPHATE 64 2.8 5-ENOLPYRUVYLSHIKIMIC ACID 3-PHOSPHATE
(5-EPS-3-P) 67 2.9 CHORISMIC ACID 75 2.9.1 ISOLATION, STRUCTURE AND
PROPERTIES 75 2.9.2 SYNTHESIS 79 2.9.3 IN VITRO CONVERSIO N TO PREPHENIC
ACID 83 2.10 QUINICACID 90 VIII CONTENTS CHAPTER 3 ENZYMES AND
ENZYMOLOGY OF THE COMMON PATHWAY 103 3.1 INTRODUCTION 103 3.2
3-DEOXY-D-ARAWNO-HEPTULOSONATE 7-PHOSPHATE (DAHP) SYNTHASE 106 3.2.1
MECHANISM OF ACTION OF DAHP SYNTHASE 110 3.3 3-DEHYDROQUINATE SYNTHASE
116 3.4 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) 123 3.5
SHIKIMATE DEHYDROGENASE (SHIKIMATE OXIDOREDUCTASE) 124 3.6 SHIKIMATE
KINASE 126 3.7 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE (5-EPS-3-P) SYNTHASE
127 3.7.1 ENZYMOLOGY 127 3.7.2 GLYPHOSATE AND THE INHIBITION OF
5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE 136 3.8 CHORISMATE SYNTHASE
139 3.9 INDUCIBLE CATABOLISM OF QUINIC AND SHIKIMIC ACIDS 144 CHAPTER 4
BEYOND CHORISMATE - PRIMARY ESSENTIAL METABOLITES 156 4.1 INTRODUCTION
157 4.2 PATHWAYS TO L-PHENYLALANINE AND L-TYROSINE 160 4.2.1 PATHWAY
DIVERSITY AND AMBIGUITY 160 4.2.2 PREPHENIC ACID 162 4.2.3 L-AROGENATE
164 4.2.4 MONOFUNCTIONAL CHORISMATE MUTASES 166 4.2.5 BIFUNCTIONAL
CHORISMATE MUTASES 168 4.2.6 MONOFUNCTIONAL PREPHENATE DEHYDRATASE AND
PREPHENATE DEHYDROGENASE 172 4.2.7 AMINOTRANSFERASES 173 4.2.8
L-AROGENATE ( PRETYROSINE ) METABOLISM 173 4.2.9 CHORISMATE
MUTASE*MECHANISM OF ACTION 175 4.3 PATHWAY TO L-TRYPTOPHAN 184 4.3.1
ORGANISATION OF ENZYMES*COMPARATIVE ASPECTS 184 4.3.2 ANTHRANILATE
SYNTHASE 191 4.3.3 ANTHRANILATE PHOSPHORIBOSYL TRANSFERASE,
PHOSPHORIBOSYL-ANTHRANILATE ISOMERASE AND INDOLE-3- GLYCEROL PHOSPHATE
SYNTHASE 195 4.3.4 TRYPTOPHAN SYNTHASE 198 4.4 REGULATION OF AROMATIC
AMINO ACID SYNTHESIS 204 4.5 P-AMINOBENZOATE SYNTHESIS AND THE FOLATE
COENZYMES 206 CONTENTS IX 4.6 BENZO- AND NAPHTHO-ISOPRENOID QUINONE
BIOSYNTHESIS 210 4.6.1 INTRODUCTION*STRUCTURE AND FUNCTION 210 4.6.2
BIOSYNTHETIC PATHWAYS 213 4.7 SALICYLIC ACID, 2,3-DIHYDROXYBENZOIC ACID
AND ENTEROBACTIN 223 4.7.1 SIDEROPHORES, SALICYLIC ACID AND MYCOBACTINS
223 4.7.2 ENTEROBACTIN (ENTEROCHELIN) AND 2,3-DIHYDROXYBENZOATE 224 4.8
AROMATIC AMINO ACID METABOLISM 227 4.8.1 LIGNIN*L-PHENYLALANINE AMMONIA
LYASE (PAL) AND THE HYDROXYCINNAMATE POOL 227 4.8.2 MAMMALIAN METABOLISM
OF AROMATIC AMINO ACIDS 238 CHAPTER 5 BEYOND CHORISMATE - SECONDARY
METABOLISM 255 5.1 INTRODUCTION*SECONDARY METABOLISM 255 5.2 MICROBIAL
METABOLITES 262 5.2.1 ANTIBACTERIAL AGENTS 263 5.2.2 MYCOTOXINS 276
5.2.3 MISCELLANEOUS ANTIBIOTICS AND METABOLITES 289 5.2.4 TRYPTOPHANASE
AND TYROSINE PHENOL LYASE 304 5.3 PLANT SECONDARY METABOLITES 307 5.3.1
PLANT ALKALOIDS*EARLY BIOSYNTHETIC IDEAS 312 5.3.2 BIOSYNTHESIS OF THE
BENZYLISOQUINOLINE ALKALOIDS 315 5.3.3 ENZYMOLOGY OF BENZYLISOQUINOLINE
ALKALOID SYNTHESIS 319 5.3.4 ENZYMOLOGY OF MONOTERPENE INDOLE ALKALOID
BIOSYNTHESIS 327 5.3.5 MISCELLANEOUS NITROGEN-CONTAINING METABOLITES 328
5.3.6 PHENYLPROPANOID AND FLAVONOID BIOSYNTHESIS 331 ADDENDUM 365 INDEX
369
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| discipline | Chemie / Pharmazie Biologie Chemie |
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| indexdate | 2024-07-09T17:18:07Z |
| institution | BVB |
| isbn | 0471939994 |
| language | English |
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| physical | XII, 387 S. Ill. |
| publishDate | 1993 |
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| spelling | Haslam, Edwin Verfasser aut Shikimic acid metabolism and metabolites Edwin Haslam Chichester u.a. Wiley 1993 XII, 387 S. Ill. txt rdacontent n rdamedia nc rdacarrier Acido shiquímico - Metabolismo Shikimisäureweg (DE-588)4181142-2 gnd rswk-swf Shikimisäure (DE-588)4328368-8 gnd rswk-swf Shikimisäure (DE-588)4328368-8 s DE-604 Shikimisäureweg (DE-588)4181142-2 s GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005491696&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Haslam, Edwin Shikimic acid metabolism and metabolites Acido shiquímico - Metabolismo Shikimisäureweg (DE-588)4181142-2 gnd Shikimisäure (DE-588)4328368-8 gnd |
| subject_GND | (DE-588)4181142-2 (DE-588)4328368-8 |
| title | Shikimic acid metabolism and metabolites |
| title_auth | Shikimic acid metabolism and metabolites |
| title_exact_search | Shikimic acid metabolism and metabolites |
| title_full | Shikimic acid metabolism and metabolites Edwin Haslam |
| title_fullStr | Shikimic acid metabolism and metabolites Edwin Haslam |
| title_full_unstemmed | Shikimic acid metabolism and metabolites Edwin Haslam |
| title_short | Shikimic acid |
| title_sort | shikimic acid metabolism and metabolites |
| title_sub | metabolism and metabolites |
| topic | Acido shiquímico - Metabolismo Shikimisäureweg (DE-588)4181142-2 gnd Shikimisäure (DE-588)4328368-8 gnd |
| topic_facet | Acido shiquímico - Metabolismo Shikimisäureweg Shikimisäure |
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