Immunomodulating drugs: [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.]
Gespeichert in:
| Format: | Tagungsbericht Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
1993
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
685 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XVI, 816 S. Ill., zahlr. graph. Darst. |
| ISBN: | 0897667719 0897667727 |
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES VOLUME 685 IMMUNOMODULATING
DRUGS EDITED BY VASSIL ST. GEORGIEV AND HIDEYO YAMAJJUCHI THE NEW YORK
ACADEMY OF SCIENCES NEW YORK, NEW YORK 1993 ANNALS OF THE NEW YORK
ACADEMY OF SCIENCES VOLUME 685 JUNE 23, 1993 IMMUNOMODULATING DRUGS
EDITORS AND CONFERENCE CHAIRMEN VASSIL ST. GEORGIEV AND HIDEYO YAMAGUCHI
SESSION CHAIRS J. F. ALBRIGHT, B. G. CHRISTENSEN, G. DESTEVENS, G. B.
ELION, R. A. GOLDSTEIN, R. A. GOOD, J. E. JANIK, S. L. KELLEY, I.
KIMURA, J. R. LA MONTAGNE, R. G. LAHITA, K. MAEDA, J. J. MCGOWAN, M.
PALLADINO, A. SINGER, AND B. M. WEICHMAN CONTENTS PREFACE. BY VASSIL ST.
GEORGIEV AND HIDEYO YAMAGUCHI XV IMMUNOMODULATING DRUGS: MAJOR ADVANCES
IN RESEARCH AND DEVELOPMENT. BY VASSIL ST. GEORGIEV 1 PART I. FK-506:
CHEMISTRY AND BIOLOGICAL EVALUATION FK-506: ITS ROLE IN
IMMUNOSUPPRESSION. BY B. G. CHRISTENSEN. .. 11 DISCOVERY OF FK-506 AND
UPDATE. BY TORU KINO AND TOSHIO GOTO 13 FK-506*A NOVEL
IMMUNOSUPPRESSANT. BY WILLIAM H. PARSONS, NOLAN H. SIGAL, AND MATTHEW J.
WYVRATT 22 STRUCTURAL STUDIES OF COMPLEXED FK-506 BINDING PROTEIN. BY
JON CLARDY 37 ALLOGRAFT AND XENOGRAFT ACCEPTANCE UNDER FK-506 AND OTHER
IMMUNOSUPPRESSANT TREATMENT. BY THOMAS E. STARZL, NORIKO MURASE, ANTHONY
J. DEMETRIS, SUZANNE ILDSTAD, CAMILLO RICORDI, AND MASSIMO TRUCCO 46
FK-506 INHIBITS THE IL-2-INDEPENDENT INDUCTION OF THE ACTIVATION ANTIGEN
CD 69. BY GABRIELLE H. REEM, YONG SHI, AND SOUMAYA EL ROUBY 52 THIS
VOLUME IS THE RESULT OF A CONFERENCE ENTITLED THIRD INTERNATIONAL
CONFERENCE ON DRUG RESEARCH IN IMMUNOLOGIC AND INFECTIOUS DISEASES:
IMMUNOMODULATING DRUGS*SYNTHESIS, PRECLINICAL AND CLINICAL EVALUATION
HELD BY THE NEW YORK ACADEMY OF SCIENCES ON JUNE 27- JULY 1, 1992 IN
WASHINGTON, D.C. COMPARISON OF FK-506, RAPAMYCIN, ASCOMYCIN, AND
CYCLOSPORINE IN MOUSE MODELS OF HOST-VERSUS-GRAFT DISEASE AND
HETEROTOPIC HEART TRANSPLANTATION. BY K. W. MOLLISON, T. A. FEY, R. A.
KRAUSE, V. A. THOMAS, A. P. MEHTA, AND J. R. LULY 55 PART II.
IMMUNOSUPPRESSIVE PROPERTIES OF RAPAMYCIN RAPAMYCIN: IN VITRO PROFILE OF
A NEW IMMUNOSUPPRESSIVE MACROLIDE. BY S. N. SEHGAL AND C. C. BANSBACH 58
PREVENTION AND TREATMENT OF ALLOGRAFT REJECTION IN VIVO BY RAPAMYCIN:
MOLECULAR AND CELLULAR MECHANISMS OF ACTION. BY RANDALL ELLIS MORRIS 68
RAPAMYCIN PROLONGS SURVIVAL OF MURINE RECIPIENTS OF FULLY ALLOGENEIC
DONOR GRAFTS WHEN ADMINISTERED DURING THE GRAFT- VERSUS-HOST DISEASE
PROCESS. BY BRUCE R. BLAZAR, PATRICIA A. TAYLOR, SUREN N. SEHGAL, AND
DANIEL A. VALLERA 73 EFFECTS OF ORALLY ADMINISTERED RAPAMYCIN IN ANIMAL
MODELS OF ARTHRITIS AND OTHER AUTOIMMUNE DISEASES. BY RICHARD P.
CARLSON, WILLIAM L. BAEDER, ROBERT G. CACCESE, LINDA M. WARNER, AND
SUREN N. SEHGAL 86 RAPAMYCIN S INHIBITION OF THYMOCYTE PROLIFERATION,
UNLIKE THAT OF CYCLOSPORIN A OR PREDNISOLONE, IS NOT ASSOCIATED WITH
CYTOTOXICITY. BY CATHERINE C. BANSBACH, DAVID WANCIO, ROBERT G. CACCESE,
C. FRANK SHEN, AND SUREN N. SEHGAL 114 RAPAMYCIN INHIBITS LYMPHOCYTE
PROLIFERATION IN A POPLITEAL LYMPH NODE MODEL VIA AN IL-2-INDEPENDENT
MECHANISM. BY L. M. WARNER, G. M. LEWIS, B. M. WEICHMAN, AND S. N.
SEHGAL 117 RAPAMYCIN IN A PORCINE RENAL TRANSPLANT MODEL. BY P. S.
ALMOND, A. MOSS, R. NAKHLEH, M. MELIN, S. CHEN, A. SALAZAR, K. SHIRABE,
AND A. MATAS 121 PART III. 15-DEOXYSPERGUALIN: CHEMISTRY AND
IMMUNOSUPPRESSIVE ACTION SYNTHESIS AND BACKGROUND CHEMISTRY OF
15-DEOXYSPERGUALIN. BY KENJI MAEDA, YOSHIHISA UMEDA, AND TETSUSHI SAINO
..... 123 15-DEOXYSPERGUALIN, A NOVEL IMMUNOSUPPRESSIVE DRUG: STUDIES OF
THE MECHANISM OF ACTION. BY MARK A. TEPPER, STEVEN NADLER, CHARLES
MAZZUCCO, CHERRY SINGH, AND SUSAN L. KELLEY 136 SUCCESSFUL TREATMENT
WITH A NOVEL IMMUNOSUPPRESSIVE AGENT, DEOXYSPERGUALIN, IN TYPE II
COLLAGEN-INDUCED ARTHRITIS IN MICE. BY KYUICHI NEMOTO, TAKAKO MAE,
FUMINORI ABE, AND TOMIO TAKEUCHI 148 PRECLINICAL STUDIES WITH
15-DEOXYSPERGUALIN IN VARIOUS ANIMAL MODELS FOR AUTOIMMUNE DISEASES. BY
HANS-ULRICH SCHORLEMMER AND GERHARD DICKNEITE 155 15-DEOXYSPERGUALIN: A
NOVEL IMMUNOSUPPRESSIVE DRUG WITH CLINICAL POTENTIAL. BY FRANCIS T.
THOMAS, MARK A. TEPPER, JUDITH M. THOMAS, AND CARL E. HAISCH 175
DEOXYSPERGUALIN IN ALLOGENEIC KIDNEY AND XENOGENEIC ISLET
TRANSPLANTATION: EARLY CLINICAL TRIALS. BY CARL G. GROTH 193
DEOXYSPERGUALIN: CLINICAL TRIALS IN RENAL GRAFT REJECTION. BY HIROSHI
AMEMIYA FOR THE JAPAN COLLABORATIVE TRANSPLANT STUDY OF DEOXYSPERGUALIN
196 A MEMBER OF THE HSP70 FAMILY OF HEAT-SHOCK PROTEINS IS A PUTATIVE
TARGET FOR THE IMMUNOSUPPRESSANT 15-DEOXYSPERGUALIN. BY CHARLES E.
MAZZUCCO AND STEVEN G. NADLER 202 EFFECTS OF 15-DEOXYSPERGUALIN ON THE
EXPRESSION OF SURFACE IMMUNOGLOBULIN IN 70Z/3.12 MURINE PRE-B CELL LINE.
BY KRISTINE G. STERBENZ AND MARK A. TEPPER 205 PART IV. GUANINE
ARABINOSIDE AND PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS ENZYMES OF
THE PURINE METABOLISM: INHIBITION AND THERAPEUTIC POTENTIAL. BY VASSIL
ST. GEORGIEV 207 IMP DEHYDROGENASE INHIBITORS AS IMMUNOMODULATORS. BY
BEVERLY S. MITCHELL, JENNIFER S. DAYTON, LAURENCE A. TURKA, AND CRAIG B.
THOMPSON 217 GUANINE ARABINOSIDE AS A BONE MARROW-PURGING AGENT. BY
JOANNE KURTZBERG 225 APPLICATION OF X-RAY CRYSTALLOGRAPHIC METHODS IN
THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS. BY STEVEN E.
EALICK, Y. S. BABU, CHARLES E. BUGG, MARK D. ERION, WAYNE G. GUIDA, JOHN
A. MONTGOMERY, AND JOHN A. SECRIST, III 237 ACTIVITIES OF TWO
9-DEAZAGUANINE ANALOGUE INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE,
CL-972 AND PD 141955, IN VITRO AND IN VIVO. BYK. B. GILBERTSEN, M. K.
DONG, U. JOSYULA, J. C. SIRCAR, D. J. WILBURN, AND M. C. CONROY 248 PART
V. IMMUNOMODULATING ACTIVITY OF EXPERIMENTAL THERAPEUTICS
LEVAMISOLE-INDUCED NEOPTERIN SYNTHESIS. BY JOHN JANIK, WILLIAM C. KOPP,
JOHN W. SMITH II, DAN L. LONGO, W. GREGORY ALVORD, AND WALTER J. URBA
252 EXPERIMENTAL MODULATION OF IL-1 PRODUCTION AND CELL SURFACE MOLECULE
EXPRESSION BY LEVAMISOLE. BY EDWARD S. KIMBALL 259 RECENT CLINICAL
TRIALS WITH LEVAMISOLE. BY MICHAEL R. KURMAN. .. 269 SEX HORMONES AS
IMMUNOMODULATORS OF DISEASE. BY ROBERT G. LAHITA 278 CORTICOSTEROIDS AS
IMMUNOMODULATORS. BY HENRY N. CLAMAN .... 288 ANDROSTENEDIOL REGULATES
SYSTEMIC RESISTANCE AGAINST LETHAL INFECTIONS IN MICE. BY ROGER M. LORIA
AND DAVID A. PADGETT 293 OVERVIEW ON THE CHEMISTRY AND IMMUNOMODULATING
PROPERTIES OF NOVEL PYRIMIDINONES. BY WENDELL WIERENGA 296 BROPIRIMINE
IN BLADDER CANCER: CLINICAL STUDIES. BY MICHAEL F. SAROSDY 301
IMMUNOSUPPRESSIVE ACTIVITY OF MYCOPHENOLATE MOFETIL. BY ELSIE M. EUGUI
AND ANTHONY C. ALLISON 309 MOLECULAR MECHANISMS OF IMMUNOSUPPRESSION BY
CYCLOSPORINS. BY GERHARD ZENKE, GOTZ BAUMANN, ROLAND WENGER, PETER
HIESTAND, VALERIE QUESNIAUX, ELSEBETH ANDERSEN, AND MAX H. SCHREIER 330
STUDY OF THE IMMUNOSUPPRESSIVE PROPERTIES OF CYDOSPORINE ANALOGUES. BY
G. H. REEM, S. EL ROUBY AND Y. SHI 336 SUPPRESSION OF ALLOANTIGEN
PRESENTATION BY PRODIGJOSIN, A T CELL- SPECIFIC IMMUNOSUPPRESSANT. BY
JUNJI MAGAE, MASAHIRO YAMASHITA, AND KAZUO NAGAI 339 IN VIVO AND IN
VITRO EFFICACY OF FUSIDIC ACID IN HIV INFECTION. BY GIUSEPPE FAMULARO,
CLAUDIO DE SIMONE, SONIA TZANTZOGLOU, VITO TRINCHIERI, SONIA MORETTT,
AND GIORGIO TONIETTI 341 IN VIVO ANTITUMOR ACTIVITY OF THE HYPOXANTHINE
DERIVATIVES ST 789 AND ST 689. BY CLAUDIO DE SIMONE, GIUSEPPE FAMULARO,
PIETRO FORESTA, CLAUDIO ALBERTONI, AND EDOARDO ARRIGONI MARTELLI 344
SYNTHESES OF MACROMOLECULAR IMMUNOMODULATORS AND CONJUGATES EMPLOYING
HALOACETYL REAGENTS. BY JOHN K. INMAN 347 IMMUNOMODULATING ACTIVITY OF
MYELOPEPTIDES: CLINICAL TRIALS. BY REM V. PETROV 351 STRUCTURAL NATURE
AND FUNCTIONS OF TRANSFER FACTORS. BY CHARLES H. KLRKPATRICK . 362
EFFECT OF ORAL ADMINISTRATION OF HEAT-KILLED ENTEROCOCCUS FAECALIS FK-23
ON THE LEUKOCYTE-RECONSTITUTING CAPACITY IN IMMUNOSUPPRESSED DOGS, BY
TAKASHI HASEGAWA, HIROMI KANASUGI, MASAKAZU HIDAKA, SUSUMU MAKIMURA,
KATSUYUKI MIYATA, SHIGERU ABE, AND HIDEYO YAMAGUCHI 369 ANTITUMOR AND
ANTIMICROBIAL ACTIVITIES OF ENTEROCOCCAL PREPARATION ORALLY ADMINISTERED
TO MICE. BY SHIGERU ABE, KAZUTOMO OHASHI, KASTUHISA UCHIDA, TATSUO
IKEDA, SADAO KIMURA, AND HIDEYO YAMAGUCHI 372 IMMUNOSTIMULATING PEPTIDE
DERIVED FROM SOYBEAN PROTEIN. BY MASAAKI YOSHIKAWA, KATSUKI KISHI,
MASAKAZU TAKAHASHI, AKIHIRO WATANABE, TSUYOSHI MIYAMURA, MASATOSHI
YAMAZAKI, AND HIDEO CHIBA 375 TWO SIMPLE GLUCOSE DERIVATIVES WITH
OPPOSITE IMMUNOACTIVITIES. BY MEI-LING SHEN, SHI-KANG ZHAI, ZHEN-WEI LU,
AND DAVID W. OU 377 IMMUNOPHARMACOLOGIC STUDY OF GLUCOFRUCTAN FROM
SYMPHYTUM ASPERUM ROOTS. BY M. MAKHATADZE, M. BOSTOGANASHVILI, V.
BARBAKADZE, E. KEMERTELIDZE AND H. DEKANOSIDZE .... 383 CONFERENCE
LECTURESHIPS THE EDWARD JENNER LECTURE BIOLOGICAL SPINOFFS OF ORGAN
TRANSPLANTATION. BY JOSEPH E. MURRAY 389 THE GEORGE HITCHINGS AND
GERTRUDE ELIAN LECTURE THE PHARMACOLOGY OF AZATHIOPRINE. BY GERTRUDE B.
ELION 401 THE JULES BORDET LECTURE IMMUNOPATHOGENESIS OF HIV INFECTION.
BY ANTHONY S. FAUCI 409 THE GERHARD DOMAGK LECTURE TRANSCRIPTION FACTORS
IN LYMPHOID DEVELOPMENT. BY DAVID BALTIMORE 421 THE EMIT VON BEHRING
LECTURE* DEVELOPMENT AND FUNCTIONS OF GAMMA DELTA T CELLS. BY SUSUMU
TONEGAWA 429 NOT SUBMITTED. PART VI. IMMUNOMODULATING ACTIVITIES OF
ANTI-INFECTIOUS DRUGS IMMUNOMODULATING DRUGS: WHENCE AND WHITHER. BY
GEORGE DE STEVENS 430 IMMUNOMODULATOR EFFECTS ON THE FRIEND VIRUS
INFECTION IN GENETICALLY DEFINED MICE. BY R. W. SIDWELL, J. D. MORREY,
K. M. OKLEBLERRY, R. A. BURGER, AND R. P. WARREN 432 IMMUNOMODULATING
ACTIVITY OF ANTIFUNGAL DRUGS. BY HIDEYO YAMAGUCHI, SHIGERU ABE, AND
YOSHIKO TOKUDA 447 IMMUNOPHARMACOLOGIC PROPERTIES OF INOSINE 5 -METHYL
MONOPHOSPHATE (MIMP). BY M. SOSA, A. SAHA, A. GINER-SOROLLA, E. HADDEN,
AND J. W. HADDEN 458 IMMUNOMODULATORY PROPERTIES OF AZT. BY ROBERT J.
MCKALLIP, MITZI NAGARKATTI, AND PRAKASH NAGARKATTI 464 ANTIVIRAL
ACTIVITY OF A SYNTHETIC DOUBLE-STRANDED POLYRIBONUCLEOTIDE INTERFERON
INDUCER IN A MURINE AIDS RETROVIRUS MODEL. BY PAUL L. BLACK, KATHERINE
M. MCKINNON, SHARON L. WOODEN, AND MICHAEL A. USSERY 467 PART VII.
TREATMENT OF INFECTIOUS DISEASES AND SEPSIS: INTERVENTION BY IMMUNE
REGULATION MODULATION OF CYTOKINE RESPONSES IN SEPSIS. BY STEPHEN F.
LOWRY AND LYLE L. MOLDAWER 471 INTERVENTIONS FOR THE TREATMENT OF SEPTIC
SHOCK. BY IRENE S. FIGARI AND MICHAEL A. PALLADINO 483 PLEIOTROPIC
EFFECTS OF TRANSFORMING GROWTH FACTOR-/? ON CELLS OF THE IMMUNE SYSTEM.
BY FRANCIS RUSCETTI, LUIGI VARESIO, AUGUSTO OCHOA, AND JOHN ORTALDO 488
TGF/3 AND HIV INFECTION. BY MARTIN LOTZ AND PRADEEP SETH ... 501 PART
VIII. IMMUNOMODULATING PROPERTIES OF PEPTIDES IN ALLERGIC AND AUTOIMMUNE
DISEASES CYTOKINES AND MODULATION OF DISEASES OF IMMEDIATE
HYPERSENSITIVITY. BY MARSHALL PLAUT 512 THERAPEUTIC PEPTIDES THAT BLOCK
INTERACTION OF T CELLS WITH MHC IN EXPERIMENTAL ALLERGIC
ENCEPHALOMYELITIS. BY LAWRENCE STEINMAN 521 ANTIGEN PRESENTATION BY THE
MURINE RENAL PROXIMAL TUBULE: A MECHANISM OF SELF TOLERANCE? BY DAVID T.
HAGERTY AND PAUL M. ALLEN 525 PART IX. KAMPO MEDICINE (JAPANESE HERBAL
MEDICINE) AND ITS IMMUNOMODULATING EFFECTS WITH SPECIAL REFERENCE TO
INTRACTABLE ASTHMA IMMUNOLOGIC ASPECTS OF KAMPO MEDICINE. BY IKURO
KIMURA 529 INHIBITION OF HYPERSENSITIVITY REACTIONS BY SAIBOKU-TO
(TJ-96), PARTICULARLY ON TYPE IV REACTION. BY AKTHIDE KODA 543 EFFECT OF
SAIBOKU-TO (TJ-96) ON BRONCHIAL ASTHMA: INDUCTION OF GLUCOCORTICOID
RECEPTOR, /J-ADRENALINE RECEPTOR, IGE-FC E RECEPTOR EXPRESSION AND ITS
EFFECT ON EXPERIMENTAL IMMEDIATE AND LATE ASTHMATIC REACTION. BY
SHIGENORI NAKAJIMA, YUJI TOHDA, KENTARO OHKAWA, JUNICHI CHIHARA, AND
YUKIO NAGASAKA 549 EFFECT OF AN HERBAL PREPARATION, SAIBOKU-TO (TJ-96),
ON ANTIGEN- INDUCED AIRWAY HYPERRESPONSIVENESS AND EOSINOPHIL
INFILTRATION IN ACTIVELY SENSITIZED GUINEA PIGS. BY M. TODA, S.
MOTOJIMA, T. FUKUDA, AND S. MAKINO 561 EFFECTS OF SAIBOKU-TO (TJ-96) ON
THE PRODUCTION OF PLATELET- ACTIVATING FACTOR IN HUMAN NEUTROPHILS. BY
TSUNEYOSHI NAKAMURA, MOTOAKI KURIYAMA, ERI KOSUGE, KEIKO ISHIHARA, AND
KOJI ITO 572 A MULTICENTER CLINICAL TRIAL OF TJ-96 IN PATIENTS WITH
STEROID- DEPENDENT BRONCHIAL ASTHMA: A COMPARISON OF GROUPS ALLOCATED BY
THE ENVELOPE METHOD. BY YOSUKE EGASHIRA AND HITOSHI NAGANO 580 PART X.
CYTOKINES AND REGULATION OF THE IMMUNE RESPONSE CYTOKINES AND THEIR ROLE
AS GROWTH FACTORS AND IN REGULATION OF IMMUNE RESPONSES. BY VASSIL ST.
GEORGIEV AND JOSEPH F. ALBRIGHT 584 THE INTERLEUKIN-2 RECEPTOR: A TARGET
FOR IMMUNOTHERAPY. BY THOMAS A. WALDMANN, CAROLYN GOLDMAN, LOIS TOP,
ANGUS GRANT, JACK BURTON, RICHARD BAMFORD, ERICH ROESSLER, IVAN HORAK,
SARA ZAKNOEN, CLAUDE KASTEN- SPORTES, JEFFREY WHITE, RICHARD ENGLAND,
EVA HORAK, JEAN MARTTNUCCI, SIKIRU A. TINUBU, BIBHUTI MISHRA, RICHARD
JUNGHANS, MICHAEL DIPRE, JORGE CARRASQUILLO, JAMES REYNOLDS, OTTO
GANSOW, AND DAVID NELSON 603 THE ROLE OF THE T CELL RECEPTOR A CHAIN IN
ANTIGEN-SPECIFIC IMMUNE SUPPRESSION. BY MICHAEL C. BYRNE, RICHARD M.
O HARA, JR., VIJAY K. KUCHROO, SUNDARARAJAN JAYARAMAN, ANJANA RAO,
MARTIN E. DORF, AND MARY COLLINS 611 INCREASED LEVELS OF LEUKOTRIENE B 4
AND INTERLEUKIN-8 IN PSORIATIC SKIN. BY RENZA DEGIULIO, CATERINA
MONTEMARTINI, ANTONINO MAZZONE, DAVIDE PASOTTI, ANTONIO DONADINI, AND
GIOVANNI RICEVUTI 614 NK CELLS AND INTERFERON AS MEDIATORS OF BIOLOGICAL
RESPONSE MODIFIER-MEDIATED PROTECTION AGAINST MCMV AND HSV-2 INFECTION
IN NORMAL AND IMMUNOCOMPROMISED MICE. BY S. C. KUNDER AND P. S. MORAHAN
618 PART XI. DRUG METABOLIZING ENZYMES AND THE IMMUNE SYSTEM IMMUNE
DYSFUNCTION RELATED TO DRUG-METABOLIZING ENZYMES. BY JOSEPH F. ALBRIGHT
620 ROLE OF THE AH RECEPTOR AND THE DIOXIN-INDUCIBLE (AH) GENE BATTERY
IN TOXICITY, CANCER, AND SIGNAL TRANSDUCTION. BY DANIEL W. NEBERT,
ALVARO PUGA, AND VASILIS VASILIOU ... 624 AUTOANTIBODIES AGAINST
CYTOCHROMES P-450 IN DRUG-INDUCED AUTOIMMUNE HEPATITIS. BY P. H. BEAUNE
AND M. BOURDI 641 IMMUNITY TO HALOTHANE METABOLITE-MODIFIED PROTEINS IN
HALOTHARIE HEPATITIS. BY J. GERALD KENNA, TRUDY L. KNIGHT, AND FRANK N.
A. M. VAN PELT 646 EFFECTS OF SMALL DOSES OF DIOXINS ON THE IMMUNE
SYSTEM OF MARMOSETS AND RATS. BY REINHARD NEUBERT, RALF STAHLMANN, MARIA
KORTE, HENK VAN LOVEREN, JOSEPH G. VOS, GEORG GOLOR, JESSIE R. WEBB,
HANS HELGE, AND DIETHER NEUBERT 662 PART XII. NOVEL STRATEGIES FOR
IMMUNOTHERAPY IMMUNOLOGIC APPROACHES TO THE THERAPY OF HIV-1 INFECTION.
BY MICHAEL C. SNELLER AND H. CLIFFORD LANE 687 GENE TRANSFER FOR THERAPY
AND PROPHYLAXIS OF HIV-1 INFECTION. BY MARK L. ROHRBAUGH AND JOHN J.
MCGOWAN 697 MODULATION OF MACROPHAGE FUNCTION BY TRANSFORMING GROWTH
FACTOR /3, INTERLEUKIN 4, AND INTERLEUKIN 10. BY CHRISTIAN BOGDAN AND
CARL NATHAN 713 PSEUDOMONAS EXOTOXIN AND RECOMBINANT IMMUNOTOXINS
DERIVED FROM IT. BY DAVID FITZGERALD AND IRA PASTAN 740 SUPERANTIGENS IN
INFECTIOUS DISEASES, INCLUDING AIDS. BY JEFFREY LAURENCE, ANDREW S.
HODTSEV, AND DAVID N. POSNETT ... 746 RNA DRUG THERAPY ACTING VIA THE
2-5A SYNTHETASE/RNASE L PATHWAY. BY ROBERT J. SUHADOLNIK, NANCY L.
REICHENBACH, PATRICIA M. HITZGES, DHARAM V. ABLASHI, DAVID R. STRAYER,
AND WILLIAM A. CARTER 756 SPECIFIC RNA DRUG THERAPY OF HEPATITIS
VIRUSES. BY WILLIAM A. CARTER, ROBERT J. SUHADOLNIK, WERNER E. G.
MULLER, BRENT E. KORBA, HOWARD R. HUBBELL, GABRIEL GARCIA, AND DAVID R.
STRAYER 758 IMMUNOREHABILITATION IN PATIENTS WITH HERPES SIMPLEX. BY
TENGIZ TSERTSVADZE, NIKOLAI SHAVDIA, IRAKLI MEBONIA, TSISANA SHARTAVA,
MANANA GVABERIDZE, AND MALVINA ALADASHVILI 762 QUANTITATIVE
DETERMINATION OF HLA-DR ANTIGEN EXPRESSION ON CELL SURFACES WITH
MONOCLONAL ANTIBODY BY DOT-ELISA. BY ZHAO XIAOJUAN AND ZHANG JIYING 765
ROLE OF INCREASE OF OPIOID RECEPTORS IN GRANULOCYTE CDLLB/CD18
DYSFUNCTION. BY ANTONINO MAZZONE, GIOVANNI RICEVUTI, DAVIDE PASOTTI,
GIANLUCA FOSSATI, IOLANDA MAZZUCCHELLI, PAOLA CAVIGLIANO, SERGIO
LECCHINI, GIANMARIO FRIGO, AND ANTONIA NOTARIO 770 IMMUNOSUPPRESSIVE
EFFECTS OF LYMPHOCYTE-SPECIFIC HISTAMINE CONGENER TREATMENT OF AN
ADOPTIVE TRANSFER MODEL. BY NINA K. GARLIE, PARISA KHOSROPOUR, AND
KENNETH L. MELMON 774 PART XIII. VACCINES: RECENT PROGRESS IN
DEVELOPMENT ISSUES IN THE DEVELOPMENT OF A PROPHYLACTIC HIV VACCINE. BY
DANIEL HOTH 777 T CELL VACCINES FOR AUTOIMMUNE DISEASES. BY FELIX MOR
AND IRUN R. COHEN 784 VACCINES BASED ON SYNTHETIC POLYIONS AND PEPTIDES.
BY RAKHIM M. KHAITOV 788 ADVANCES IN INFLUENZA VIRUS VACCINE RESEARCH.
BY ROBERT B. COUCH 803 INDEX OF CONTRIBUTORS 813
|
| any_adam_object | 1 |
| author_GND | (DE-588)121687732 |
| building | Verbundindex |
| bvnumber | BV008185607 |
| callnumber-first | Q - Science |
| callnumber-label | Q11 |
| callnumber-raw | Q11 RM373 |
| callnumber-search | Q11 RM373 |
| callnumber-sort | Q 211 |
| callnumber-subject | Q - General Science |
| classification_tum | CHE 880f MED 450f |
| ctrlnum | (OCoLC)28112312 (DE-599)BVBBV008185607 |
| dewey-full | 615/.7 500 |
| dewey-hundreds | 600 - Technology (Applied sciences) 500 - Natural sciences and mathematics |
| dewey-ones | 615 - Pharmacology and therapeutics 500 - Natural sciences and mathematics |
| dewey-raw | 615/.7 500 |
| dewey-search | 615/.7 500 |
| dewey-sort | 3615 17 |
| dewey-tens | 610 - Medicine and health 500 - Natural sciences and mathematics |
| discipline | Allgemeine Naturwissenschaft Chemie Medizin |
| format | Conference Proceeding Book |
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| genre | (DE-588)1071861417 Konferenzschrift 1992 Washington DC gnd-content |
| genre_facet | Konferenzschrift 1992 Washington DC |
| id | DE-604.BV008185607 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T17:15:59Z |
| institution | BVB |
| institution_GND | (DE-588)1301003-7 |
| isbn | 0897667719 0897667727 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-005402458 |
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| owner | DE-12 DE-355 DE-BY-UBR DE-20 DE-188 |
| owner_facet | DE-12 DE-355 DE-BY-UBR DE-20 DE-188 |
| physical | XVI, 816 S. Ill., zahlr. graph. Darst. |
| publishDate | 1993 |
| publishDateSearch | 1993 |
| publishDateSort | 1993 |
| publisher | New York Acad. of Sciences |
| record_format | marc |
| series | Annals of the New York Academy of Sciences |
| series2 | Annals of the New York Academy of Sciences |
| spelling | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] ed. by Vassil St. Georgiev ... New York, NY New York Acad. of Sciences 1993 XVI, 816 S. Ill., zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 685 Literaturangaben Immunopharmacologie - Congrès Immunosuppresseurs - Congrès Immunosuppressie gtt Immunotherapie gtt Immunothérapie - Congrès Adjuvants, Immunologic pharmacology Japan Congresses Herbal Medicine Japan Congresses Immunopharmacology Congresses Immunosuppressive Agents pharmacology Japan Congresses Immunosuppressive drugs Congresses Immunotherapy Japan Congresses Immunsuppressivum (DE-588)4161389-2 gnd rswk-swf Immunmodulator (DE-588)4315156-5 gnd rswk-swf Cytoplasmatische Therapie (DE-588)4113261-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1992 Washington DC gnd-content Cytoplasmatische Therapie (DE-588)4113261-0 s DE-604 Immunsuppressivum (DE-588)4161389-2 s Immunmodulator (DE-588)4315156-5 s Georgiev, Vassil St. Sonstige (DE-588)121687732 oth International Conference on Drug Research in Immunologic and Infectious Diseases 3 1992 Washington, DC Sonstige (DE-588)1301003-7 oth Annals of the New York Academy of Sciences 685 (DE-604)BV002532608 685 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005402458&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] Annals of the New York Academy of Sciences Immunopharmacologie - Congrès Immunosuppresseurs - Congrès Immunosuppressie gtt Immunotherapie gtt Immunothérapie - Congrès Adjuvants, Immunologic pharmacology Japan Congresses Herbal Medicine Japan Congresses Immunopharmacology Congresses Immunosuppressive Agents pharmacology Japan Congresses Immunosuppressive drugs Congresses Immunotherapy Japan Congresses Immunsuppressivum (DE-588)4161389-2 gnd Immunmodulator (DE-588)4315156-5 gnd Cytoplasmatische Therapie (DE-588)4113261-0 gnd |
| subject_GND | (DE-588)4161389-2 (DE-588)4315156-5 (DE-588)4113261-0 (DE-588)1071861417 |
| title | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] |
| title_auth | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] |
| title_exact_search | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] |
| title_full | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] ed. by Vassil St. Georgiev ... |
| title_fullStr | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] ed. by Vassil St. Georgiev ... |
| title_full_unstemmed | Immunomodulating drugs [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] ed. by Vassil St. Georgiev ... |
| title_short | Immunomodulating drugs |
| title_sort | immunomodulating drugs this volume is the result of a conference entitled third international conference on drug research in immunologic and infectious diseases immunomodulating drugs synthesis preclinical and clinical evaluation held by the new york academy of sciences on june 27 july 1 1992 in washington d c |
| title_sub | [this volume is the result of a conference entitled Third International Conference on Drug Research in Immunologic and Infectious Diseases: Immunomodulating Drugs - Synthesis, Preclinical and Clinical Evaluation held by the New York Academy of Sciences on June 27 - July 1, 1992 in Washington, D.C.] |
| topic | Immunopharmacologie - Congrès Immunosuppresseurs - Congrès Immunosuppressie gtt Immunotherapie gtt Immunothérapie - Congrès Adjuvants, Immunologic pharmacology Japan Congresses Herbal Medicine Japan Congresses Immunopharmacology Congresses Immunosuppressive Agents pharmacology Japan Congresses Immunosuppressive drugs Congresses Immunotherapy Japan Congresses Immunsuppressivum (DE-588)4161389-2 gnd Immunmodulator (DE-588)4315156-5 gnd Cytoplasmatische Therapie (DE-588)4113261-0 gnd |
| topic_facet | Immunopharmacologie - Congrès Immunosuppresseurs - Congrès Immunosuppressie Immunotherapie Immunothérapie - Congrès Adjuvants, Immunologic pharmacology Japan Congresses Herbal Medicine Japan Congresses Immunopharmacology Congresses Immunosuppressive Agents pharmacology Japan Congresses Immunosuppressive drugs Congresses Immunotherapy Japan Congresses Immunsuppressivum Immunmodulator Cytoplasmatische Therapie Konferenzschrift 1992 Washington DC |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005402458&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002532608 |
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