Molecular and cellular aspects of basement membranes:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego u.a.
Acad. Press
1993
|
| Schriftenreihe: | Cell biology
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 448 S. Ill., graph. Darst. |
| ISBN: | 0125931654 |
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Datensatz im Suchindex
| _version_ | 1804122407656488960 |
|---|---|
| adam_text | Molecular and Cellular Aspects
of Basement Membranes
Edited by
David H Rohrbach
Center for Biotechnology and Bioengineering
and the Department of Microbiology-Biochemistry
School of Dental Medicine
University of Pittsburgh
Pittsburgh, Pennsylvania
Rupert Timpl
Department of Protein Chemistry
Max-Planck Institut fur Biochemie
Martinsreid, Germany
ACADEMIC PRESS, INC
Harcourt Brace Jovanovich, Publishers
San Diego New York Boston London Sydney Tokyo Toronto
Contents
Contributors xiii
Preface xvii
I Organization and Definition of the Basement Membrane
1 Collagen and Basement Membranes: Discovery and Progress
George R Martin and Karl A Piez
I Historical Background 3
II Major Components of Basement Membranes 7
References 13
2 Supramolecular Organization of Basement Membranes
Peter D Yurchenco and Jules O Rear
I Introduction 20
II Morphology and Heterogeneity of Basement Membranes 21
III Mechanisms of Matrix Assembly 23
IV Type IV Collagen 24
V Laminin 31
VI Glycosaminoglycans and Proteoglycans 36
VII Other Basement Membrane Components 39
VIII Basement Membrane Structure Model 41
References 43
3 Dermal-Epidermal Adhesion in Skin
Robert E Burgeson
I Introduction: infrastructure of Dermal-Epidermal Junction 49
II Hemidesmosomes 53
III Anchoring Filament 54
IV Anchoring Fibrils and Anchoring Plaques 56
vii
viii Contents
V Inherited Diseases Involving Failure of Dermal-Epidermal Anchoring
Complex 57
VI Origin of Dermal-Epidermal Junction 59
VII Summary 60
References 61
4 Basement Membrane Molecules in Vertebrate
Nervous System
Joshua R Sanes
I Introduction 67
II Neuromuscular Junction 68
III Peripheral Nervous System 75
IV Central Nervous System 78
References 81
5 Glomerular Basement Membrane: Biology and Physiology
B S Kasinath and Yashpat S Kanwar
I Introduction 89
II Biology and Biochemistry of Glomerular Basement Membrane 91
III Physiology of Glomerular Basement Membrane 96
References 102
6 Role of Water of Hydration in Filtration Function of
Proteoglycans of Basement Membrane
Christine L Haskin, Ivan L Cameron, and David H Rohrbach
I Water Content of Basement Membranes 107
II Use of Nuclear Magnetic Resonance as Measure of Hydration 109
III Role of Proteoglycans in Filtration Function of Basement Membrane 113
IV Role of Water in Basement Membrane Function 114
V Conclusion 115
References 116
II Basement Membrane Components, Biochemical Nature,
Molecular Structure, and Gene Regulation
7 Genes and Regulation of Basement Membrane Collagen
and Laminin Synthesis
Yoshihiko Yamada and Klaus Kiihn
I Introduction 121
II Structure of Type IV Collagen Genes 123
Contents ix
III Laminin Genes and Transcription 137
References 143
8 Structure and Function of Laminin
Jiirgen Engel
I Introduction 147
II Occurrence and Sources of Laminins 148
III Gross Structure of Mouse Engelbreth-Holm-Swarm Laminin and
Fragmentation 151
IV Biochemical and Biophysical Approaches to Elucidation of Laminin
Structure 155
V Detailed Model of Laminin Molecule and Variations 158
VI Biosynthesis and Assembly of Polypeptide Chains into Functional
Molecules 163
VII Assignment of Functions to Individual Domains 165
VIII Laminins in Comparison to Other Multidomain Glycoproteins of
Extracellular Matrix 167
References 171
9 Laminin and Collagen IV Variants and Heterogeneity
in Basement Membrane Composition
Mats Paulsson
I Evidence for Heterogeneity in Basement Membrane Composition 177
II Structure of Laminin Variants 178
III Tissue Distribution and Biological Activity of Laminin Variants 181
IV Structure of Collagen IV Variants 182
V Tissue Distribution of Collagen IV Variants 184
VI Perspectives 184
References 185
10 Proteoglycans of Basement Membranes
Douglas M Noonan and John R Hassell
I Proteoglycan Structure and Nomenclature 189
II Perlecan: Large Multidomain Proteoglycan of Basement Membranes
f 190
HI Other Proteoglycans in Basement Membranes 203
IV Summary 206
References 206
11 Other Basement Membrane Proteins and Their Calcium-
Binding Potential
Rupert Timpl and Monique Aumailley
I Introduction 211
II Nidogen/Entactin 213
Contents
III BM-40/Osteonectin/SPARC 219
IV Proteins Shared by Basement Membranes and Blood 223
V Site-Specific and Other Basement Membrane Proteins 225
VI Perspectives 228
References 229
III Effect of Cellular Interactions with
Basement Membranes
12 Integrin Structure and Ligand Specificity
in Cell-Matrix Interactions
Randall H Kramer Judy Enenstein, and Nahid S Waleh
I Introduction 239
II Primary Structure of Integrin Subunits 241
III Ligand-Binding Specificity 247
IV Integrins and Signal Transduction 250
V Role of Integrins in Tissue Remodeling 254
VI Conclusion 257
References 258
13 Proteoglycans of Plasma Membranes: Multiple Functions
in Cell Surface Biology
Alan C Rapraeger
I Families of Cell Surface Proteoglycans 267
II Polymorphic CD44 Family 268
III Melanoma Proteoglycan/NG2 270
IV Glypican 271
V Betaglycan 273
VI The Syndecan Family 273
VII Role of Syndecans in Action of Heparin-Binding Growth Factors 281
VIII Summary 282
References : 283
14 Peptide Sequences in Matrix Proteins Recognized
by Adhesion Receptors
Martin J Humphries
I Introduction 289
II Aspartate-Containing Peptide Motifs 292
III Other Active Sites 298
IV Structural Basis of Ligand-Receptor Binding 301
Contents XI
V Concluding Remarks 304
References 304
15 Role of Basement Membrane in Differentiation
Hynda K Kleinman, Maura C Kibbey, H William Schnaper, Mark A Hadley,
Martin Dym, and Derrick S Grant
I Introduction 309
II Preparation and Components of Matrigel 310
III Differentiation Induced by Matrigel 312
IV Role of Laminin in Cell Differentiation 318
V Summary 322
References 323
16 Extracellular Matrix-Bound Growth Factors, Enzymes,
and Plasma Proteins
Israel Vlodavsky, Rachel Bar-Shavit, Gil Korner, and Zvi Fuks
I Introduction 327
II Extracellular Matrix-Bound Growth Factors and Cytokines 328
III Extracellular Matrix-Bound Plasma Proteins and Enzymes 337
IV Concluding Remarks 338
References 339
17 Role of Extracellular Matrix in Cell Migration and Invasion
Simon L Goodman
I Introduction 345
II Motors, Clutches, and Contacts with the Outside World 346
III Cell Migration during Embryogenesis 347
IV Collagenases and Other Enzymes as Matrix Remodelers 353
V Biological Effects of Remodeling Basement Membranes 354
VI Concluding Remarks - 355
References - 355
18 Basement Membranes in Development
Peter Ekblom
I Extracellular Matrices during Development 359
II Basement Membrane Components during Preimplantation Development 360
III Basement Membranes as Regulators of Epithelial Cell Development 365
IV Basement Membranes during Angiogenesis 373
V Significance of Basement Membrane Heterogeneity during Development 375
VI Concluding Remarks 377
References 378
xii Contents
19 Molecular Aspects of Basement Membrane Pathology
David H Rohrbach and Valerie A Murrah
I Introduction 386
II Diabetes 386
III Polycystic Kidney Disease 395
IV Goodpasture s Syndrome 406
V Conclusions 409
References 410
20 Alport Syndrome and Other Inherited Basement
Membrane Disorders
Karl Tryggvason, Jing Zhou, and Sirkka Liisa Hostikka
I Introduction 421
II Alport Syndrome: Hereditary Nephritis 423
III Epidermolysis Bullosa 431
IV Other Inherited Basement Membrane Disorders 433
References 435
Index 439
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| spelling | Molecular and cellular aspects of basement membranes ed. by David H. Rohrbach ... San Diego u.a. Acad. Press 1993 XIX, 448 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cell biology Membrana (citologia) larpcal Extracellular Matrix Extracellular Matrix Proteins Extracellular matrix Membrane, Basement Membranes Grundsubstanz (DE-588)4224942-9 gnd rswk-swf Basalmembran (DE-588)4144086-9 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Cytologie (DE-588)4070177-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Basalmembran (DE-588)4144086-9 s DE-604 Molekularbiologie (DE-588)4039983-7 s Grundsubstanz (DE-588)4224942-9 s Cytologie (DE-588)4070177-3 s Rohrbach, David H. Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005291914&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular and cellular aspects of basement membranes Membrana (citologia) larpcal Extracellular Matrix Extracellular Matrix Proteins Extracellular matrix Membrane, Basement Membranes Grundsubstanz (DE-588)4224942-9 gnd Basalmembran (DE-588)4144086-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Cytologie (DE-588)4070177-3 gnd |
| subject_GND | (DE-588)4224942-9 (DE-588)4144086-9 (DE-588)4039983-7 (DE-588)4070177-3 (DE-588)4143413-4 |
| title | Molecular and cellular aspects of basement membranes |
| title_auth | Molecular and cellular aspects of basement membranes |
| title_exact_search | Molecular and cellular aspects of basement membranes |
| title_full | Molecular and cellular aspects of basement membranes ed. by David H. Rohrbach ... |
| title_fullStr | Molecular and cellular aspects of basement membranes ed. by David H. Rohrbach ... |
| title_full_unstemmed | Molecular and cellular aspects of basement membranes ed. by David H. Rohrbach ... |
| title_short | Molecular and cellular aspects of basement membranes |
| title_sort | molecular and cellular aspects of basement membranes |
| topic | Membrana (citologia) larpcal Extracellular Matrix Extracellular Matrix Proteins Extracellular matrix Membrane, Basement Membranes Grundsubstanz (DE-588)4224942-9 gnd Basalmembran (DE-588)4144086-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Cytologie (DE-588)4070177-3 gnd |
| topic_facet | Membrana (citologia) Extracellular Matrix Extracellular Matrix Proteins Extracellular matrix Membrane, Basement Membranes Grundsubstanz Basalmembran Molekularbiologie Cytologie Aufsatzsammlung |
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