Biosynthesis of heme and chlorophylls:
Gespeichert in:
Format: | Buch |
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Sprache: | English |
Veröffentlicht: |
New York u.a.
McGraw-Hill
1990
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Literaturangaben |
Beschreibung: | XIV, 594 S. Ill., graph. Darst. |
ISBN: | 0070150885 |
Internformat
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Datensatz im Suchindex
_version_ | 1804122040104386560 |
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adam_text | Biosynthesis
of Heme
and Chlorophylls
Harry A Dailey
Department of Microbiology
University of Georgia
Athens, Georgia
McGraw-Hill Publishing Company
New York St Louis San Francisco Auckland Bogota
Caracas Hamburg Lisbon London Madrid Mexico
Milan Montreal New Delhi Oklahoma City
Paris San Juan Sao Paulo Singapore
Sydney Tokyo Toronto
Contents
Contributors lx
Preface xi
Acknowledgments xll
Nomenclature Conventions xiii
Chapter 1 A Historical Introduction to Porphyrins and Porphyrias
Michael R Moore
I Introduction 1
II Structure 2
III Chemistry and Biochemistry 4
IV Early Description of Porphyria 11
V Classification of the Porphyrias 13
VI Enzymes 18
VII Acute Porphyria 21
VIII Nonacute Porphyrias 25
IX Porphyrinurias and Pseudoporphyria 29
X Porphyrin Synthesis in the Animal Kingdom 31
XI Phototherapy and Cancer 35
XII Royal Malady 36
XIII Werewolves 38
XIV Epilogue 42
REFERENCES 42 -
Chapter 2 The Biosynthesis of 5-Aminolevulinic Acid and Its
Transformation into Coproporphyrinogen in Animals and Bacteria 55
Peter M Jordan
I Introduction 55
II Biosynthesis of 5-Aminolevulinic Acid 59
III Biosynthesis of 5-Aminolevulinic Acid from Glutamate 68
IV Biosynthesis of Porphobilinogen 73
V Biosynthesis of Uroporphyrinogen III 83
VI Biosynthesis of Coproporphyrinogen III 106
REFERENCES 112
vi Contents
Chapter 3 Conversion of Coproporphyrinogen to Protoheme in
Higher Eukaryotes and Bacteria: Terminal Three Enzymes 123
Harry A Dailey
I Introduction 123
II Eukaryotic Coproporphyrinogen Oxidase 124
III Eukaryotic Protoporphyrinogen Oxidase 129
IV Eukaryotic Ferrochelatase 133
V Iron Reduction 149
VI Possible Complex of the Terminal Three Enzymes 150
VII Terminal Three Steps in Prokaryotes 151
REFERENCES 155
Chapter 4 Regulation of Heme Biosynthesis in Higher Animals 163
Tamara L Andrew, Pascale G Rlley, and Harry A Dailey
I Introduction 163
II Regulation in Nonerythroid Cells 164
III Regulation in Erythroid Cells 176
REFERENCES 189
Chapter 5 Molecular Biology of Eukaryotic 5-Aminolevulinate
Synthase 201
Peter Dlerks
I Perspectives and Summary 201
II Molecular and Genetic Characterization: Evidence
for a Multigene System 205
III Regulatory Mechanisms in Hepatic Cells 215
IV Regulatory Mechanisms in Erythroid Cells 223
REFERENCES 229
Chapter 6 Tetrapyrrole and Heme Biosynthesis in the Yeast
Saccharomyces cerevlslae 235
Roslne Labbe-Bols and Pierre Labbe
I Introduction 235
II Tetrapyrroles and Heme-Proteins of S cerevisiae 238
III Overview of the Heme Pathway of S cerevisiae 245
IV Individual Enzymes: Enzymology, Genetics, and Regulations 252
V Conclusions 275
NOMENCLATURE 276
REFERENCES 277
Chapter 7 Tetrapyrrole Metabolism in Photosynthetic Organisms 287
Samuel I Beale and Jon D Welnstein
I Variety and Functions of Tetrapyrroles in Photosynthetic Organisms 287
II Biosynthetic Route 291
III Regulation 342
REFERENCES 368
Contents vii
Chapter 8 Iron Metabolism in Relation to Heme Synthesis 393
Prem Ponka, Herbert M Schulman, and Timothy M Cox
I Introduction 393
II Proteins of Iron Transport and Storage 398
III Mechanism of Iron Supply for Heme Synthesis 405
IV Coordination of Heme and Globin Synthesis in Erythroid Cells 416
V Control of Heme Biosynthesis in Erythroid Cells:
Role of Iron Transport 417
VI Conclusions 422
REFERENCES 423
Chapter 9 Transport of Tetrapyrroles: Mechanisms and Biological
and Regulatory Consequences 435
Ann Smith
I Introduction 435
II Heme Transport from Extracellular Sources 442
HI Intracellular Movement of Tetrapyrroles 459
IV Summary and Conclusions 477
REFERENCES 479
Chapter 10 Human Hereditary Porphyrias 491
Yves Nordmann and Jean-Charles Deybach
I Introduction 491
II Hepatic Porphyrias 493
III Erythropoietic Porphyrias 519
REFERENCES 530
Chapter 11 Heme Degradation and Biosynthesis of Bilins 543
Stanley B Brown, Jennifer D Houghton, and Angela Wllks
I Introduction 543
II Mammalian Heme Breakdown 546
III Heme Oxygenase 552
IV Coupled Oxidation as a Model for Biological Heme Breakdown 562
V Mechanism of Heme Degradation 564
VI Heme Breakdown in Plants: Biosynthesis of Phycobiliproteins 569
REFERENCES 571
Index S77
|
any_adam_object | 1 |
building | Verbundindex |
bvnumber | BV007682548 |
callnumber-first | Q - Science |
callnumber-label | QP671 |
callnumber-raw | QP671.H45 |
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classification_rvk | WD 5380 |
ctrlnum | (OCoLC)19815288 (DE-599)BVBBV007682548 |
dewey-full | 574.19/297 |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 574 - [Unassigned] |
dewey-raw | 574.19/297 |
dewey-search | 574.19/297 |
dewey-sort | 3574.19 3297 |
dewey-tens | 570 - Biology |
discipline | Biologie |
format | Book |
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id | DE-604.BV007682548 |
illustrated | Illustrated |
indexdate | 2024-07-09T17:07:33Z |
institution | BVB |
isbn | 0070150885 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-005040549 |
oclc_num | 19815288 |
open_access_boolean | |
owner | DE-355 DE-BY-UBR DE-11 DE-188 |
owner_facet | DE-355 DE-BY-UBR DE-11 DE-188 |
physical | XIV, 594 S. Ill., graph. Darst. |
publishDate | 1990 |
publishDateSearch | 1990 |
publishDateSort | 1990 |
publisher | McGraw-Hill |
record_format | marc |
spelling | Biosynthesis of heme and chlorophylls Harry A. Dailey New York u.a. McGraw-Hill 1990 XIV, 594 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Chlorophylle - Synthèse Hème - Synthèse Chlorophyll Synthesis Heme Synthesis Häm (DE-588)4244498-6 gnd rswk-swf Biosynthese (DE-588)4006902-3 gnd rswk-swf Blut (DE-588)4007259-9 gnd rswk-swf Chlorophyll (DE-588)4147817-4 gnd rswk-swf Blut (DE-588)4007259-9 s Biosynthese (DE-588)4006902-3 s DE-604 Häm (DE-588)4244498-6 s DE-188 Chlorophyll (DE-588)4147817-4 s Dailey, Harry A. Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005040549&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Biosynthesis of heme and chlorophylls Chlorophylle - Synthèse Hème - Synthèse Chlorophyll Synthesis Heme Synthesis Häm (DE-588)4244498-6 gnd Biosynthese (DE-588)4006902-3 gnd Blut (DE-588)4007259-9 gnd Chlorophyll (DE-588)4147817-4 gnd |
subject_GND | (DE-588)4244498-6 (DE-588)4006902-3 (DE-588)4007259-9 (DE-588)4147817-4 |
title | Biosynthesis of heme and chlorophylls |
title_auth | Biosynthesis of heme and chlorophylls |
title_exact_search | Biosynthesis of heme and chlorophylls |
title_full | Biosynthesis of heme and chlorophylls Harry A. Dailey |
title_fullStr | Biosynthesis of heme and chlorophylls Harry A. Dailey |
title_full_unstemmed | Biosynthesis of heme and chlorophylls Harry A. Dailey |
title_short | Biosynthesis of heme and chlorophylls |
title_sort | biosynthesis of heme and chlorophylls |
topic | Chlorophylle - Synthèse Hème - Synthèse Chlorophyll Synthesis Heme Synthesis Häm (DE-588)4244498-6 gnd Biosynthese (DE-588)4006902-3 gnd Blut (DE-588)4007259-9 gnd Chlorophyll (DE-588)4147817-4 gnd |
topic_facet | Chlorophylle - Synthèse Hème - Synthèse Chlorophyll Synthesis Heme Synthesis Häm Biosynthese Blut Chlorophyll |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005040549&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT daileyharrya biosynthesisofhemeandchlorophylls |