Chemiluminescence immunoassay:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
1992
|
| Schriftenreihe: | Wilson and Wilson's comprehensive analytical chemistry
29 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 293 S. Ill., graph. Darst. |
| ISBN: | 0444890351 |
Internformat
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| 336 | |b txt |2 rdacontent | ||
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| 650 | 4 | |a Chimiluminescence | |
| 650 | 4 | |a Chemiluminescence immunoassay | |
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Datensatz im Suchindex
| _version_ | 1804118918509363200 |
|---|---|
| adam_text | Wilson and Wilson s
COMPREHENSIVE ANALYTICAL CHEMISTRY
Edited by
G SVEHLA, Ph D,D Sc ,FRSO,FICI
Professor of Analytical Chemistry
University College, Cork, Ireland
VOLUME XXIX
CHEMILUMINESCENCE
IMMUNOASSAY
by
IAN WEEKS
ELSEVIER
AMSTERDAM-LONDON-NEW YORK-TOKYO
Contents
Editor s Preface XI
Author s Preface XIII
Acknowledgements XIV
Chapter 1 INTRODUCTION 1
References 5
Chapter 2 CHEMILUMINESCENCE: THE PHENOMENON 7
2 1 Photochemical and photophysical processes 7
2 2 Luminescence 13
2 3 Chemiluminescence in vivo: bioluminescence 16
2 4 Chemiluminescence in vitro 20
2 5 Mechanistic aspects 25
2 6 Measurement 46
References 51
Chapter 3 IMMUNOASSAY 53
3 1 Historical 53
3 2 Labelled-antigen and labelled-antibody t echniques 69
3 3 Radioactive and non-radioactive labels 87
3 4 Immunoassay design 103
3 5 The influence of the label on the choice of architecture 113
References 118
Chapter 4 THE IMMUNOCHEMICAL/PHOTOCHEMICAL
INTERFACE 121
4 1 Suitable chemiluminescent molecules 121
ix
4 2 Direct coupling: potential chemistries 129
4 3 Indirect coupling 143
4 4 The potential of bioluminescent systems 147
References 151
Chapter 5 CHEMILUMINESCENCE IMMUNOASSAYS:
THE EARLY WORK 153
5 1 The luminol experience 153
5 2 Isoluminol derivatives 155
5 3 Indirect chemiluminescence immunoassays 160
5 4 Immunoassays for small molecules 162
5 5 Immunoassays for large molecules 172
5 6 Enzyme mediated systems 180
References 183
Chapter 6 HOMOGENEOUS IMMUNOASSAYS 187
6 1 Monitoring changes in kinetics and intensity 188
6 2 Monitoring changes in wavelength 194
6 3 Examples of homogeneous chemiluminiscence immunoas
says 197
References 202
Chapter 7 CHEMILUMINESCENCE IMMUNOASSAYS:
STATE OF THE ART 203
7 1 Indirect systems 215
7 2 Phthalhydrazide labels 222
7 3 Acridinium labels 225
7 4 Practical aspects 255
References 257
Chapter 8 FUTURE PROSPECTS 261
8 1 Future developments in chemiluminescence immunoassay 261
8 2 The impact on the clinical laboratory 268
8 3 The impact in other areas of analysis 271
Conclusion 274
References 274
Appendix I 275
Appendix II 285
Subject Index 291
x
|
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| indexdate | 2024-07-09T16:17:56Z |
| institution | BVB |
| isbn | 0444890351 |
| language | English |
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| physical | XVI, 293 S. Ill., graph. Darst. |
| publishDate | 1992 |
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| series | Wilson and Wilson's comprehensive analytical chemistry |
| series2 | Wilson and Wilson's comprehensive analytical chemistry |
| spelling | Weeks, Ian Verfasser aut Chemiluminescence immunoassay by Ian Weeks Amsterdam [u.a.] Elsevier 1992 XVI, 293 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Wilson and Wilson's comprehensive analytical chemistry 29 Chimiluminescence Chemiluminescence immunoassay Chemilumineszenz (DE-588)4147623-2 gnd rswk-swf Immunassay (DE-588)4113998-7 gnd rswk-swf Chemilumineszenz (DE-588)4147623-2 s Immunassay (DE-588)4113998-7 s DE-604 Wilson and Wilson's comprehensive analytical chemistry 29 (DE-604)BV000900805 29 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002956827&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Weeks, Ian Chemiluminescence immunoassay Wilson and Wilson's comprehensive analytical chemistry Chimiluminescence Chemiluminescence immunoassay Chemilumineszenz (DE-588)4147623-2 gnd Immunassay (DE-588)4113998-7 gnd |
| subject_GND | (DE-588)4147623-2 (DE-588)4113998-7 |
| title | Chemiluminescence immunoassay |
| title_auth | Chemiluminescence immunoassay |
| title_exact_search | Chemiluminescence immunoassay |
| title_full | Chemiluminescence immunoassay by Ian Weeks |
| title_fullStr | Chemiluminescence immunoassay by Ian Weeks |
| title_full_unstemmed | Chemiluminescence immunoassay by Ian Weeks |
| title_short | Chemiluminescence immunoassay |
| title_sort | chemiluminescence immunoassay |
| topic | Chimiluminescence Chemiluminescence immunoassay Chemilumineszenz (DE-588)4147623-2 gnd Immunassay (DE-588)4113998-7 gnd |
| topic_facet | Chimiluminescence Chemiluminescence immunoassay Chemilumineszenz Immunassay |
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