Handbook of pharmacokinetics: toxicity assessment of chemicals
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Chichester
Horwood u.a.
1989
|
| Ausgabe: | 1. publ. |
| Schriftenreihe: | Ellis Horwood series in pharmaceutical technology
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VIII, 704 S. graph. Darst. |
| ISBN: | 0745802567 0470215720 |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1804118802348113920 |
|---|---|
| adam_text | HANDBOOK OF
PHARMACOKINETICS
Toxicity Assessment of Chemicals
J P LABAUNE
Laboratories Anphar-Rolland
Chilly Mazarin, France
ELLIS HORWOOD LIMITED
Publishers • Chichester
Halsted Press: a division of
JOHN WILEY amp; SONS
New York • Chichester • Brisbane • Toronto
Table of Contents
Preface vii
Introduction 1
PART ONE BIO AVAILABILITY
1 Absorption 9
2 First Pass Effect 41
3 Absolute Bioavailability 80
4 Relative Bioavailability I l l
PART TWO DISTRIBUTION
5 Binding to Blood Fractions 135
6 Tissue Distribution 176
PART THREE CLEARANCE
7 The Concept of Clearance 209
8 Renal Clearance 218
9 Hepatic Clearance 250
Table of Contents vi
PART FOUR THE INTERPRETATION OF KINETIC DATA
10 Intravenous Route 293
11 Intravenouslnfusion 317
12 Oral Administration 324
13 Summary of Pharmacokinetic Equations 339
14 Interpretation of the Data: Limitations 345
15 Influence of Physiological Factors on Pharmacotientics
Parameters 349
16 The Pharmacokentic Classification of Drugs 404
17 Metabolite Kinetics 413
18 Non-Linear Pharmacokinetics 460
19 Species Differences in the Pharmacokentic Extrapolation
of Data from Animal to Man 499
PART FIVE CLINICAL PHARMACOKENTICS
20 Chronic Administration 541
21 Drug Interactions 569
22 The Influence of Physiological States 601
23 Effects of Pathological States 651
Index 695
|
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| dewey-full | 615/.7 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
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| dewey-search | 615/.7 |
| dewey-sort | 3615 17 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1. publ. |
| format | Book |
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| id | DE-604.BV004685759 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T16:16:05Z |
| institution | BVB |
| isbn | 0745802567 0470215720 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-002877720 |
| oclc_num | 489826166 |
| open_access_boolean | |
| owner | DE-12 DE-19 DE-BY-UBM DE-188 |
| owner_facet | DE-12 DE-19 DE-BY-UBM DE-188 |
| physical | VIII, 704 S. graph. Darst. |
| publishDate | 1989 |
| publishDateSearch | 1989 |
| publishDateSort | 1989 |
| publisher | Horwood u.a. |
| record_format | marc |
| series2 | Ellis Horwood series in pharmaceutical technology |
| spelling | Labaune, Jean-Pierre Verfasser aut Pharmacocinétique Handbook of pharmacokinetics toxicity assessment of chemicals J. P. Labaune 1. publ. Chichester Horwood u.a. 1989 VIII, 704 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Ellis Horwood series in pharmaceutical technology Pharmacocinétique - Manuels comme sujet Pharmacocinétique ram Pharmacokinetics Pharmacokinetics handbooks Pharmakokinetik (DE-588)4115557-9 gnd rswk-swf Pharmakokinetik (DE-588)4115557-9 s DE-604 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002877720&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Labaune, Jean-Pierre Handbook of pharmacokinetics toxicity assessment of chemicals Pharmacocinétique - Manuels comme sujet Pharmacocinétique ram Pharmacokinetics Pharmacokinetics handbooks Pharmakokinetik (DE-588)4115557-9 gnd |
| subject_GND | (DE-588)4115557-9 |
| title | Handbook of pharmacokinetics toxicity assessment of chemicals |
| title_alt | Pharmacocinétique |
| title_auth | Handbook of pharmacokinetics toxicity assessment of chemicals |
| title_exact_search | Handbook of pharmacokinetics toxicity assessment of chemicals |
| title_full | Handbook of pharmacokinetics toxicity assessment of chemicals J. P. Labaune |
| title_fullStr | Handbook of pharmacokinetics toxicity assessment of chemicals J. P. Labaune |
| title_full_unstemmed | Handbook of pharmacokinetics toxicity assessment of chemicals J. P. Labaune |
| title_short | Handbook of pharmacokinetics |
| title_sort | handbook of pharmacokinetics toxicity assessment of chemicals |
| title_sub | toxicity assessment of chemicals |
| topic | Pharmacocinétique - Manuels comme sujet Pharmacocinétique ram Pharmacokinetics Pharmacokinetics handbooks Pharmakokinetik (DE-588)4115557-9 gnd |
| topic_facet | Pharmacocinétique - Manuels comme sujet Pharmacocinétique Pharmacokinetics Pharmacokinetics handbooks Pharmakokinetik |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002877720&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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