Practical chemotherapy of malaria: report of a WHO Scientific Group
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Geneva
1990
|
| Schriftenreihe: | World Health Organization: WHO technical report series
805 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 141 S. |
| ISBN: | 9241208058 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804118736571990016 |
|---|---|
| adam_text | THIS REPORT CONTAINS THE COLLECTIVE VIEWS OF AN INTERNATIONAL GROUP OF
EXPERTS AND DOES NOT NECESSARILY REPRESENT THE DECISIONS OR THE STATED
POLICY OF THE WORLD HEALTH ORGANIZATION CHEMOTHERAPY OF MALARIA REPORT
OF A WHO SCIENTIFIC GROUP WORLD HEALTH ORGANIZATION TECHNICAL REPORT
SERIES 805 WORLD HEALTH ORGANIZATION, GENEVA 1990 CONTENTS PAGE
INTRODUCTION 7 REFERENCES (INTRODUCTION) 8 1. GENERAL CONSIDERATIONS FOR
THE DEVELOPMENT OF A MALARIA TREATMENT POLICY 9 1.1 EPIDEMIOLOGICAL
CONSIDERATIONS 9 1.2 MALARIA SERVICES 10 1.3 TREATMENT TARGETS AND
REGIMENS 12 1.4 PATTERNS OF DRUG USE 14 1.5 INSTRUCTIONS TO HEALTH
WORKERS 15 1.6 CHANGING POLICIES 16 REFERENCES (SECTION 1) 16 2. SOME
ASPECTS OF DIAGNOSIS 17 2.1 DIAGNOSTIC REQUIREMENTS AND PRACTICES 17
2.1.1 ASSESSMENT OF SYMPTOMS 17 2.1.2 LABORATORY SERVICES 19 2.2
DIAGNOSIS BY LIGHT MICROSCOPY 20 2.3 RISKS ASSOCIATED WITH THE TAKING OF
BLOOD FOR SMEARS OR SAMPLING 22 REFERENCES (SECTION 2) 23 3. THE
MANAGEMENT AND TREATMENT OF UNCOMPLICATED MALARIA : . 24 3.1 PRINCIPLES
OF THERAPY 24 3.1.1 EVALUATION 24 3.1.2 ASSESSMENT OF PRIOR THERAPY 25
3.1.3 SELECTION OF THERAPY 25 3.2 ANTIMALARIAL DRUGS 25 3.2.1
CHLOROQUINE 25 3.2.2 AMODIAQUINE 27 3.2.3 QUININE 27 3.2.4 QUINIDINE 29
3.2.5 MEFLOQUINE 30 3.2.6 PRIMAQUINE 34 3.2.7 TETRACYCLINE 35 3.3 DRUG
ASSOCIATIONS AND FIXED COMBINATIONS 37 3.3.1 ANTIMETABOLITES OF THE
FOLATE PATHWAY 38 3.3.2 COMBINATIONS OF ARTEMISININ AND ITS DERIVATIVES
WITH OTHER DRUGS 40 3.4 ANTIMALARIAL CHEMOTHERAPY OF PREGNANT WOMEN 41
3.5 ADMINISTRATION OF ANTIMALARIALS TO INFANTS AND CHILDREN * 43 3.6
ACCESSORY TREATMENT ; 44 3.6.1 REHYDRATION ... 44 3.6.2 ANTIPYRETICS 44
3.6.3 ANAEMIA 44 3.7 HAZARDS OF THE CASUAL, UNDOCUMENTED USE OF
ANTIMALARIALS 44 3.8 THE NEED FOR SIMPLE OPERATIONAL TESTS FOR
ANTIMALARIALS IN BLOOD AND URINE 45 REFERENCES (SECTION 3) 46 4. THE
MANAGEMENT AND TREATMENT OF SEVERE FALCIPARUM MALARIA 52 4.1
CHARACTERISTICS OF SEVERE FALCIPARUM MALARIA 52 4.2 VOMITING AND THE
NEED FOR INITIAL PARENTERAL CHEMOTHERAPY 54 4.3 PRINCIPLES OF MANAGEMENT
OF SEVERE FALCIPARUM MALARIA 54 4.3.1 GENERAL PRINCIPLES 54 4.3.2
PRINCIPLES OF EARLY TREATMENT *. 55 4.4 ANTIMALARIAL DRUGS 57 4.4.1
QUININE 57 4.4.2 MEFLOQUINE 60 4.4.3 CHLOROQUINE 60 4.4.4
SULFADOXINE/PYRIMETHAMINE 62 4.4.5 ARTEMISININ AND ITS DERIVATIVES 63
4.4.6 QUINIDINE 63 4.5 TREATMENT OF COMPLICATIONS 64 4.5.1 ANAEMIA 64
4.5.2 DISSEMINATED INTRAVASCULAR COAGULATION (DIC) 65 4.5.3
HYPOGLYCAEMIA 65 4.5.4 CEREBRAL MALARIA 66 4.5.5 DISTURBANCES OF FLUID,
ELECTROLYTE, AND ACID-BASE BALANCE 67 4.5.6 EXCHANGE TRANSFUSION IN
HYPERPARASITAEMIA 69 4.5.7 SEVERE FALCIPARUM MALARIA IN PREGNANCY 70 4.6
MANAGEMENT OF SEVERE AND COMPLICATED MALARIA AT VARIOUS LEVELS OF HEALTH
CARE 71 4.6.1 FACILITIES INTENDED TO PROVIDE MINIMUM CARE 71 4.6.2
FACILITIES INTENDED TO PROVIDE INTERMEDIATE CARE . : 72 4.6.3 FACILITIES
INTENDED TO PROVIDE THE MAXIMUM POSSIBLE CARE 74 REFERENCES (SECTION 4)
74 5. MALARIA CHEMOPROPHYLAXIS 78 5.1 PROBLEMS ASSOCIATED WITH
CHEMOPROPHYLAXIS 79 5.1.1 DRUG RESISTANCE 79 5.1.2 COMPLIANCE AND THE
LOGISTICS OF DELIVERY 80 5.1.3 IMPAIRMENT OF THE ACQUISITION OF IMMUNITY
81 5.1.4 PROPHYLACTIC EFFICACY OF ANTIMALARIAL DRUGS 82 5.1.5 ADVERSE
REACTIONS 82 5.2 CHEMOPROPHYLAXIS FOR SPECIAL GROUPS 83 5.2.1 PREGNANT
WOMEN * 84 5.2.2 NONIMMUNE PERSONS (E.G., TRAVELLERS) 85 REFERENCES
(SECTION 5) 89 6. MONITORING SYSTEMS 90 6.1 MONITORING DRUG EFFICACY 91
6.2 MONITORING ADVERSE REACTIONS 92 6.2.1 GENERAL CONSIDERATIONS -. 92
6.2.2 MONITORING ADVERSE REACTIONS IN ENDEMIC COUNTRIES 93 REFERENCES
(SECTION 6) 94 7. PROCUREMENT AND DISTRIBUTION OF ANTIMALARIAL DRUGS 95
7.1 PRESCRIPTION OF ANTIMALARIALS 96 7.2 NETWORKS FOR DISTRIBUTION 96
7.3 GOVERNMENT PURCHASES 98 7.4 SELECTION OF THE ANTIMALARIAL DRUG TO BE
USED 99 7.4.1 THE PUBLIC SECTOR 102 7.4.2 THE PRIVATE SECTOR 104 7.5
USER CHARGES 105 7.6 PRICES AND PRICING POLICIES 106 REFERENCES (SECTION
7) 108 NEW DRUGS 109 8.1 HALOFANTRINE 109 8.1.1 PHARMACOKINETICS ILL
8.1.2 CLINICAL AND FIELD STUDIES 112 8.2 CHLOROQUINE COMBINATIONS TO
REVERSE RESISTANCE 112 8.3 ARTEMISININ AND ITS DERIVATIVES 114 8.3.1
PRECLINICAL STUDIES 114 8.3.2 NEW DOSAGE FORMS AND CLINICAL EXPERIENCE
117 8.3.3 OPERATIONAL IMPLICATIONS 120 8.4 TRIOXANES, TETRAOXANES, AND
PEROXIDES 120 8.5 MANNICH BASES 122 8.6 BENFLUMETOL 124 8.7
HYDROXYPIPERAQUINE 126 8.8 HYDROXYNAPHTHOQUINONES 127 8.9
8-AMINOQUINOLINES : 128 8.10 PYRIDINEMETHANOLS 128 8.11 ACRIDINONES 129
REFERENCES (SECTION 8) 129 CONCLUSIONS AND RECOMMENDATIONS *: 131 9.1
TREATMENT POLICY 131 9.2 DIAGNOSIS 132 9.3 TREATMENT OF UNCOMPLICATED
MALARIA 133 9.4 TREATMENT OF SEVERE MALARIA ?. 134 9.5 PROPHYLAXIS 136
9.6 MONITORING 136 9.7 DRUG PROCUREMENT AND DISTRIBUTION 137 9.8 NEW
DRUGS 138 9.9 MALARIA TREATMENT INFORMATION 139 9.10 RESEARCH PRIORITIES
140
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| indexdate | 2024-07-09T16:15:02Z |
| institution | BVB |
| isbn | 9241208058 |
| language | English |
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| physical | 141 S. |
| publishDate | 1990 |
| publishDateSearch | 1990 |
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| series | World Health Organization: WHO technical report series |
| series2 | World Health Organization: WHO technical report series |
| spelling | Practical chemotherapy of malaria report of a WHO Scientific Group Geneva 1990 141 S. txt rdacontent n rdamedia nc rdacarrier World Health Organization: WHO technical report series 805 Antimalarials Malaria Chemotherapy Malaria Prevention Antimalariamittel (DE-588)4142684-8 gnd rswk-swf Malaria (DE-588)4037197-9 gnd rswk-swf Chemotherapie (DE-588)4127083-6 gnd rswk-swf Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Pharmakologie (DE-588)4045687-0 gnd rswk-swf Malaria (DE-588)4037197-9 s Pharmakotherapie (DE-588)4076066-2 s DE-604 Antimalariamittel (DE-588)4142684-8 s Pharmakologie (DE-588)4045687-0 s Chemotherapie (DE-588)4127083-6 s World Health Organization: WHO technical report series 805 (DE-604)BV002555442 805 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002837011&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Practical chemotherapy of malaria report of a WHO Scientific Group World Health Organization: WHO technical report series Antimalarials Malaria Chemotherapy Malaria Prevention Antimalariamittel (DE-588)4142684-8 gnd Malaria (DE-588)4037197-9 gnd Chemotherapie (DE-588)4127083-6 gnd Pharmakotherapie (DE-588)4076066-2 gnd Pharmakologie (DE-588)4045687-0 gnd |
| subject_GND | (DE-588)4142684-8 (DE-588)4037197-9 (DE-588)4127083-6 (DE-588)4076066-2 (DE-588)4045687-0 |
| title | Practical chemotherapy of malaria report of a WHO Scientific Group |
| title_auth | Practical chemotherapy of malaria report of a WHO Scientific Group |
| title_exact_search | Practical chemotherapy of malaria report of a WHO Scientific Group |
| title_full | Practical chemotherapy of malaria report of a WHO Scientific Group |
| title_fullStr | Practical chemotherapy of malaria report of a WHO Scientific Group |
| title_full_unstemmed | Practical chemotherapy of malaria report of a WHO Scientific Group |
| title_short | Practical chemotherapy of malaria |
| title_sort | practical chemotherapy of malaria report of a who scientific group |
| title_sub | report of a WHO Scientific Group |
| topic | Antimalarials Malaria Chemotherapy Malaria Prevention Antimalariamittel (DE-588)4142684-8 gnd Malaria (DE-588)4037197-9 gnd Chemotherapie (DE-588)4127083-6 gnd Pharmakotherapie (DE-588)4076066-2 gnd Pharmakologie (DE-588)4045687-0 gnd |
| topic_facet | Antimalarials Malaria Chemotherapy Malaria Prevention Antimalariamittel Malaria Chemotherapie Pharmakotherapie Pharmakologie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002837011&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002555442 |