Percutaneous absorption: mechanisms - methodology - drug delivery
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York u.a.
Dekker
1989
|
| Ausgabe: | 2. ed., rev. and expanded |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 664 S. Ill., graph. Darst. |
| ISBN: | 0824780361 |
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Datensatz im Suchindex
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| adam_text | 5~0 PERCUTANEOUS ABSORPTION MECHANISMS-METHODOLOGY-DRUG DELIVERY EDITED
BY ROBERT L BRONAUGH DIVISION OF TOXICOLOGY FOOD AND DRUG ADMINISTRATION
WASHINGTON, D.C. HOWARD I. MAI BACH DEPARTMENT OF DERMATOLOGY UNIVERSITY
OF CALIFORNIA SCHOOL OF MEDICINE SAN FRANCISCO, CALIFORNIA MARCEL
DEKKER, INC. NEW YORK AND BASEL CONTENTS INTRODUCTION TO THE SERIES III
PREFACE V CONTRIBUTORS VII MECHANISMS OF ABSORPTION 1. MATHEMATICAL
MODELS OF PERCUTANEOUS ABSORPTION RICHARD H. 3 GUY AND JONATHAN HADGRAFT
MODELS UTILIZING FICK S FIRST LAW * MODELS UTILIZING FICK S SECOND LAW *
PHARMACOKINETIC MODELS * REFERENCES 2. MECHANISM OF PERCUTANEOUS
ABSORPTION FROM PHYSICOCHEMICAL EVIDENCE GORDON L. FLYNN 17 GENERAL
TECHNIQUES OF MEMBRANE CHARACTERIZATION * PARTITIONING EF- FECTS ON
PERCUTANEOUS ABSORPTION * INFLUENCE OF PH ON PERMEABIL- ITY OF WEAK
ELECTROLYTES * BARRIER PROPERTIES AS REVEALED BY MEM- BRANE SECTIONING *
CHEMICAL AND THERMAL EFFECTS AND BARRIER PROPER- TY * INTEGRATION OF
ANATOMY WITH THE PHYSICOCHEMICAL EVIDENCE * REFERENCES 3. SKIN BINDING
DURING PERCUTANEOUS PENETRATION EFRAIM MENCZEL, 43 DANIEL A. W. BUCKS,
RONALD C. WESTER, AND HOWARD I. MAIBACH EPIDERMAL RETENTION OF CHEMICALS
IN PERCUTANEOUS PENETRATION * DERMAL ASSOCIATION WITH CHEMICALS IN
PERCUTANEOUS PENETRATION * BINDING AFFINITY VERSUS PARTITIONING OF
CHEMICALS INTO SKIN * TISSUE * SEQUENTIAL BINDING OF CHEMICALS IN
PERCUTANEOUS ABSORPTION * CONCLUSIONS * REFERENCES XI XII CONTENTS 4.
SKIN METABOLISM: THEORETICAL RICHARD H. GUY AND JONATHAN 57 HADGRAFT
THEORETICAL MODELS * REFERENCES 5. CUTANEOUS METABOLISM OF XENOBIOTICS
PATRICK K. NOONAN AND 65 RONALD C. WESTER STEROID METABOLISM * CUTANEOUS
METABOLISM OF POLYCYCLIC ARO- MATIC HYDROCARBONS * MISCELLANEOUS
CUTANEOUS METABOLIC REAC- TIONS * ENZYME INDUCTION AND INHIBITION *
PHARMACOLOGICAL AND TOXICOLOGICAL IMPLICATIONS OF SKIN METABOLISM * SKIN
METABOLISM AND PERCUTANEOUS ABSORPTION * DISCUSSION * REFERENCES 6.
FACILITATED PERCUTANEOUS ABSORPTION OF ANIONIC DRUGS 87 JONATHAN
HADGRAFT AND PAUL K. WOTTON FACILITATED TRANSPORT: THE MECHANISM * IN
VITRO MODELING OF SKIN ABSORPTION * IN VITRO PERMEATION OF SALICYLATE
ACROSS HUMAN SKIN * REFERENCES 7. THE EFFECT OF HYDRATION ON THE
PERMEABILITY OF THE SKIN IRVIN 97 H. BLANK REFERENCES 8.
STRUCTURE-ACTIVITY CORRELATIONS IN PERCUTANEOUS ABSORPTION 107 RONALD C.
WESTER AND HOWARD I. MAIBACH PARTITION COEFFICIENT * CHEMICAL STRUCTURE
AND PERCUTANEOUS ABSORPTION * MOLECULAR WEIGHT * IONIZATION * VAPOR
PRESSURE * COLINEARITY * DISCUSSION * REFERENCES 9.
DERMATOPHARMACOKINETICS IN CLINICAL DERMATOLOGY RONALD C. 125 WESTER AND
HOWARD I. MAIBACH DOSE AND DOSING REGIMEN: CLINICAL AND TOXICOLOGICAL
IMPLICATIONS * INDIVIDUAL AND SITE VARIATIONS * PERCUTANEOUS ABSORPTION
IN DISEASED SKIN * SPECIAL CONSIDERATION FOR THE NEONATE * REFERENCES
10. SKIN DELIPIDIZATION AND PERCUTANEOUS ABSORPTION EFRAIM 133 MENCZEL
SKIN LIPIDS * SKIN DELIPIDIZATION * PERCUTANEOUS ABSORPTION AFTER SKIN
DELIPIDIZATION * PERCUTANEOUS HAZARDS OF ORGANIC SOLVENTS * CONCLUSIONS
* REFERENCES 11 . SKIN DEPOSITION AND PENETRATION OF TRICLOCARBAN HELEN
NORTH- 141 ROOT, NEAL CORBIN, AND JANIS DEMETRULIAS DEPOSITION *
PERCUTANEOUS PENETRATION * DISCUSSION * REFERENCES CONTENTS XIII 12.
TOPICAL PHARMACOKINETICS OF [ 14 C] BUTYLATED HYDROXYTOLUENE IN THE
GUINEA PIG SANDRINE I. COURTHEOUX, JEAN-PAUL MARTY, AND 153 JACQUES L.
WEPIERRE EXPERIMENTAL * RESULTS * DISCUSSION * CONCLUSION * REFERENCES
13. PERCUTANEOUS ABSORPTION: COMPUTER SIMULATION USING MULTI-
COMPARTMENTED MEMBRANE MODELS JOEL L. ZATZ 165 DESCRIPTION OF THE MODELS
* SIMULATION STUDIES * CONCLUSIONS * REFERENCES 14. INFLUENCE OF AGE ON
PERCUTANEOUS ABSORPTION OF DRUG SUBSTANCES 183 CHARANJITR. BEHL, NANCY
H. BELLANTONE, AND GORDON L. FLYNN IN VIVO PERCUTANEOUS ABSORPTION
STUDIES * IN VITRO SKIN PERMEATION STUDIES * REFERENCES 15. IN VITRO
STUDIES ON THE PERMEABILITY OF INFANT SKIN LOUIS B. 213 FISHER MATERIALS
AND METHODS * CALCULATIONS * RESULTS * DISCUSSION * REFERENCES 16.
PREDICTABILITY OF IN VITRO DIFFUSION SYSTEMS: EFFECT OF SKIN TYPES AND
AGES ON PERCUTANEOUS ABSORPTION OF TRICLOCARBAN RONALD 223 C. WESTER,
HOWARD I. MAIBACH, JOHN SURIN^HAK, AND DANIEL A. W. BUCKS INTRODUCTION *
MATERIALS AND METHODS * RESULTS AND DISCUSSION * REFERENCES 17. IN VIVO
PERCUTANEOUS ABSORPTION OF PARAQUAT FROM HANDS, LEGS, AND FOREARM OF MAN
RONALD C. WESTER, HOWARD I. MAIBACH, 227 DANIEL A. W. BUCKS, AND MICHAEL
B. AUFRERE INTRODUCTION * MATERIALS AND METHODS * RESULTS * DISCUSSION *
REFERENCES : 18. INFLUENCE OF HYDRATION ON PERCUTANEOUS ABSORPTION
RONALD C. 231 WESTER AND HOWARD I. MAIBACH EARLY STUDIES * RECENT WORK *
DIRECTIONS FOR FUTURE WORK * REF- ERENCES METHODOLOGY 19. IN VIVO
METHODS FOR PERCUTANEOUS ABSORPTION MEASUREMENTS 245 RONALD C. WESTER
AND HOWARD I. MAIBACH IMPORTANCE OF IN VIVO PERCUTANEOUS ABSORPTION * IN
VIVO METHODS * FACTORS AND STEPS IN PERCUTANEOUS ABSORPTION * REFERENCES
XIV CONTENTS 20. IN VIVO ANIMAL MODELS FOR PERCUTANEOUS ABSORPTION
RONALD C. 251 WESTER AND HOWARD I. MAIBACH COMPARATIVE IN VIVO STUDIES *
COMPARATIVE IN VITRO STUDIES * THE IN VITRO MODEL * DISCUSSION *
REFERENCES 21 . DETERMINATION OF PERCUTANEOUS ABSORPTION BY IN VITRO
TECHNIQUES 267 ROBERT L. BRONAUGH IN VITRO METHODOLOGY * IN VIVO/IN
VITRO COMPARISONS * HYDROPHOBIC COMPOUNDS * ANIMAL MODELS FOR HUMAN SKIN
* SOLUBILITY PROPER- TIES OF PENETRANT * CONCLUSIONS * REFERENCES 22.
LOCALIZATION OF COMPOUNDS IN DIFFERENT SKIN LAYERS AND ITS USE AS AN
INDICATOR OF PERCUTANEOUS ABSORPTION WOLFGANG SCHALLA 281 AND HANS
SCHAEFER METHODS * DRUG CONCENTRATIONS IN THE SKIN * DRUG CONCENTRATION
IN DISEASED SKIN * INFLUX INTO THE SKIN AND EFFLUX INTO THE BODY *
CALCULATIONS OF PERCUTANEOUS RESORPTION * CONCLUSIONS AND SUM- MARY *
REFERENCES 23. EVAPORATION AND PENETRATION FROM SKIN WILLIAM G.
REIFENRATH 305 AND THOMAS S. SPENCER MODES OF LOSS FROM THE SKIN SURFACE
* METHODS * COMPARISON OF SKIN PENETRATION AND EVAPORATION IN VITRO AND
IN VIVO * FACTORS AFFECTING THE EVAPORATION AND PENETRATION PROCESS *
PHARMACO- LOGICAL SIGNIFICANCE OF EVAPORATION OF CHEMICALS FROM THE SKIN
* CONCLUSION * REFERENCES 24. DERMAL DECONTAMINATION AND PERCUTANEOUS
ABSORPTION RONALD 327 C. WESTER AND HOWARD I. MAIBACH EFFECTS OF
OCCLUSION AND WASHING * CONCLUSION: SUBSTANTIVITY * REFERENCES 25.
RADIAL TRANSPORT IN THE DENNIS RICHARD H. GUY, JONATHAN HAD- 335 GRAFT,
AND HOWARD I. MAIBACH EXPERIMENTAL OBSERVATIONS * INTERPRETATION *
CONCLUSION * REF- ERENCES 26. INTERRELATIONSHIPS IN THE DOSE RESPONSE OF
PERCUTANEOUS ABSORP - TION RONALD C. WESTER AND HOWARD I. MAIBACH 347
EFFECTS OF CONCENTRATION ON PERCUTANEOUS ABSORPTION * EFFECT OF
APPLICATION FREQUENCY * APPLICATION FREQUENCY AND TOXICITY * DIS-
CUSSION * REFERENCES 27. DOES RUBBING ENHANCE IN VIVO DERMAL ABSORPTION?
JAMES 359 MCMASTER, HOWARD I. MAIBACH, RONALD C. WESTER, AND DANIEL A.
W. BUCKS INTRODUCTION * METHODS * RESULTS * DISCUSSION * REFERENCES
CONTENTS XV 28. POLYCHLORINATED BIPHENYLS: DERMAL ABSORPTION, SYSTEMIC
ELIMINA- TION, AND DERMAL WASH EFFICIENCY RONALD C. WESTER, DANIEL 363
A. W. BUCKS, HOWARD I. MAIBACH, AND JOHN H. ANDERSON INTRODUCTION *
MATERIALS AND METHODS * RESULTS * DISCUSSION * REFERENCES 29. ARTIFICIAL
MEMBRANES AND SKIN PERMEABILITY SERGIO NACHT AND 373 DAVID YEUNG
MATERIALS AND METHODS * RESULTS * DISCUSSION * REFERENCES 30. RECEPTOR
FLUID PENETRANT INTERACTIONS AND THE IN VITRO CUTANEOUS PENETRATION OF
CHEMICALS RONALD T. RILEY AND BARBARA W, 387 KEMPPAINEN METHODS *
RESULTS AND DISCUSSION * REFERENCES 31. BLOOD FLOW STUDIES AND
PERCUTANEOUS ABSORPTION RICHARD H. 393 GUY, ETHEL TUR, RONALD C. WESTER,
AND HOWARD I. MAIBACH EXPERIMENTAL TECHNIQUES * RESULTS * CONCLUSIONS *
REFERENCES 32. HAIR DYE PENETRATION IN MONKEY AND MAN LESZEK J. WOLFRAM
409 EXPERIMENTAL * RESULTS * REFERENCES 33. PENETRATION OF MYCOTOXINS
THROUGH EXCISED HUMAN SKIN 423 BARBARA W. KEMPPAINEN, RONALD T. RILEY,
AND JUDITH G. PACE METHODS * RESULTS AND DISCUSSION * REFERENCES 34. IN
VITRO METHODS USED TO STUDY DERMAL DELIVERY AND PERCUTANE- OUS
ABSORPTION BOYD J.POULSEN AND GORDON L.FLYNN 431 IN VITRO DIFFUSION
STUDIES: NO MEMBRANE * STUDIES INVOLVING MEM- BRANES OTHER THAN THE SKIN
* IN VITRO STUDIES IN WHICH SKIN IS THE MEMBRANE * SUMMARY * REFERENCES
35. CALCULATIONS OF BODY EXPOSURE FROM PERCUTANEOUS ABSORPTION DATA
RICHARD H. GUY AND HOWARD I. MAIBACH 461 CALCULATIONS * CONCLUSIONS *
REFERENCES DRUG DELIVERY 36. PERCUTANEOUS PENETRATION AS A METHOD OF
DELIVERY TO MUSCLE AND OTHER TISSUES JEAN-PAUL MARTY, RICHARD H. GUY,
AND HOWARD I. 469 MAIBACH EXPERIMENTAL RESULTS * CONCLUSIONS *
REFERENCES 37. OPTIMIZING PERCUTANEOUS ABSORPTION BRIAN W.BARRY 48 9
CADAVER SKIN EXPERIMENTS: IN VITRO METHODS * VASOCONSTRICTOR ASSAY: IN
VIVO METHOD * CORRELATION BETWEEN OPTIMIZATION THEORY XVI CONTENTS AND
CLINICAL EFFICACY * PROTOCOL FOR OPTIMIZING A DERMATOLOGICAL FORMULATION
* REFERENCES 38. PERCUTANEOUS ABSORPTION OF CORTICOSTEROIDS: SYSTEMIC
EFFECTS 513 TORS TEN FREDRIKSSON APPROACH TO THE STUDY * METHODS AND
AMOUNTS * FREQUENCY OF APPLICATION * MEASUREMENT OF ADRENAL SUPPRESSION
* AREAS OF UN- CERTAINTY * SPECIAL CASES * REFERENCES 39. VEHICLE
EFFECTS ON SKIN PENETRATION EUGENE R. COOPER 525 DIFFUSION FACTORS *
COMPOSITIONAL AND STRUCTURAL FACTORS * PENETRA- TION ENHANCERS * SUMMARY
* REFERENCES 40. ABSORPTION OF TRIETHANOLAMINE 7-[ 14 C]SALICYLATE IN
HUMAN AND ANIMAL JOINTS JOSEPH L. RABINOWITZ AND MARTIN D. RABINOWITZ
531 HISTORICAL DEVELOPMENT * METHODOLOGY * RESULTS * CONCLUSIONS *
SUMMARY * REFERENCES 41. IN VIVO SKIN AND NITROGLYCERIN TRANSDERMAL
DELIVERY 541 RONALD C. WESTER FACTORS INFLUENCING PERCUTANEOUS
ABSORPTION * APPARENT TRANS- DERMAL ABSORPTION RATES (HUMANS) * SUMMARY
* REFERENCES 42. PHARMACODYNAMICS AND PERCUTANEOUS ABSORPTION: MINOXIDIL
STIM- ULATES CUTANEOUS BLOOD FLOW IN BALDING HUMAN SCALPS RONALD 547 C.
WESTER, HOWARD I. MAIBACH, RICHARD H. GUY, AND ERVIN NOVAK INTRODUCTION
* METHODS * RESULTS * DISCUSSION * REFERENCES 43. VEHICLES AS
PENETRATION ENHANCERS CHRISTOPHER L. GUMMER 561 COSMETIC AND THERAPEUTIC
EFFECTS * VEHICLES AS PENETRATION EN- HANCERS * DRUG SOLUBILITY * DRUG
CONCENTRATION * SKIN/VEHICLE INTERFACE * SKIN HYDRATION * PARTITION
COEFFICIENT * VEHICLE ADDI- TIVES * IDEAL VEHICLES * REFERENCES 44.
EFFECT OF A WATER VAPOR PERMEABLE FILM ON THE PERCUTANEOUS PENETRATION
OF HYDROCORTISONE DENNIS M, ANJO AND HOWARD I. 57 1 - MAIBACH MATERIALS
AND METHODS * RESULTS * DISCUSSION * REFERENCES INDEX 575
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content (DE-588)1071861417 Konferenzschrift gnd-content |
| genre_facet | Aufsatzsammlung Konferenzschrift |
| id | DE-604.BV004568301 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T16:14:25Z |
| institution | BVB |
| isbn | 0824780361 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-002810250 |
| oclc_num | 19222566 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-355 DE-BY-UBR |
| owner_facet | DE-19 DE-BY-UBM DE-355 DE-BY-UBR |
| physical | XIV, 664 S. Ill., graph. Darst. |
| publishDate | 1989 |
| publishDateSearch | 1989 |
| publishDateSort | 1989 |
| publisher | Dekker |
| record_format | marc |
| spelling | Percutaneous absorption mechanisms - methodology - drug delivery ed. by Robert L. Bronaugh ... 2. ed., rev. and expanded New York u.a. Dekker 1989 XIV, 664 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Absorption cutanée Médicaments - Administration par voie transdermique Peau - Perméabilité Skin Absorption Skin Permeability Transdermal medication Kutane Applikation (DE-588)4123924-6 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf Hautresorption (DE-588)4023861-1 gnd rswk-swf Pharmakologie (DE-588)4045687-0 gnd rswk-swf Hautkrankheit (DE-588)4023852-0 gnd rswk-swf Transdermales therapeutisches System (DE-588)4194948-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content (DE-588)1071861417 Konferenzschrift gnd-content Arzneimittel (DE-588)4003115-9 s Kutane Applikation (DE-588)4123924-6 s DE-604 Transdermales therapeutisches System (DE-588)4194948-1 s Pharmakologie (DE-588)4045687-0 s Hautkrankheit (DE-588)4023852-0 s Hautresorption (DE-588)4023861-1 s 1\p DE-604 Bronaugh, Robert L. Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002810250&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Percutaneous absorption mechanisms - methodology - drug delivery Absorption cutanée Médicaments - Administration par voie transdermique Peau - Perméabilité Skin Absorption Skin Permeability Transdermal medication Kutane Applikation (DE-588)4123924-6 gnd Arzneimittel (DE-588)4003115-9 gnd Hautresorption (DE-588)4023861-1 gnd Pharmakologie (DE-588)4045687-0 gnd Hautkrankheit (DE-588)4023852-0 gnd Transdermales therapeutisches System (DE-588)4194948-1 gnd |
| subject_GND | (DE-588)4123924-6 (DE-588)4003115-9 (DE-588)4023861-1 (DE-588)4045687-0 (DE-588)4023852-0 (DE-588)4194948-1 (DE-588)4143413-4 (DE-588)1071861417 |
| title | Percutaneous absorption mechanisms - methodology - drug delivery |
| title_auth | Percutaneous absorption mechanisms - methodology - drug delivery |
| title_exact_search | Percutaneous absorption mechanisms - methodology - drug delivery |
| title_full | Percutaneous absorption mechanisms - methodology - drug delivery ed. by Robert L. Bronaugh ... |
| title_fullStr | Percutaneous absorption mechanisms - methodology - drug delivery ed. by Robert L. Bronaugh ... |
| title_full_unstemmed | Percutaneous absorption mechanisms - methodology - drug delivery ed. by Robert L. Bronaugh ... |
| title_short | Percutaneous absorption |
| title_sort | percutaneous absorption mechanisms methodology drug delivery |
| title_sub | mechanisms - methodology - drug delivery |
| topic | Absorption cutanée Médicaments - Administration par voie transdermique Peau - Perméabilité Skin Absorption Skin Permeability Transdermal medication Kutane Applikation (DE-588)4123924-6 gnd Arzneimittel (DE-588)4003115-9 gnd Hautresorption (DE-588)4023861-1 gnd Pharmakologie (DE-588)4045687-0 gnd Hautkrankheit (DE-588)4023852-0 gnd Transdermales therapeutisches System (DE-588)4194948-1 gnd |
| topic_facet | Absorption cutanée Médicaments - Administration par voie transdermique Peau - Perméabilité Skin Absorption Skin Permeability Transdermal medication Kutane Applikation Arzneimittel Hautresorption Pharmakologie Hautkrankheit Transdermales therapeutisches System Aufsatzsammlung Konferenzschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002810250&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT bronaughrobertl percutaneousabsorptionmechanismsmethodologydrugdelivery |