Flavonoid metabolism:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Boca Raton, Fla.
CRC Press
1990
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | 298 S. graph. Darst. |
| ISBN: | 0849360854 |
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| adam_text | 270S-SO-/2 FLAVONOID METABOLISM AUTHOR HELEN A. STAFFORD, PH.D.
PROFESSOR BIOLOGY DEPARTMENT REED COLLEGE PORTLAND, OREGON CRC PRESS,
INC. BOCA RATON, FLORIDA TABLE OF CONTENTS CHAPTER 1 GENERAL ASPECTS OF
CHEMISTRY AND METABOLISM OF FLAVONOIDS 1 I. CHEMISTRY 1 A. BASIC
CHEMISTRY 1. GENERAL CHARACTERISTICS OF THE C-15 UNIT 2. HYDROXYLATION
PATTERNS OF A-, B-, AND C-RINGS B. BASIC SUBSTITUTIONS 1. HYDROXYLATION
2. METHYLATION 3 3. GLYCOSYLATION 4 4. ACYLATION 4 5. PRENYLATION 5 6.
SULFONATION 5 C. STEREOCHEMISTRY 5 1. PROBLEMS WITH R, S CONVENTION FOR
THE ABSOLUTE CONFIGURATIONS OF CARBONS 2 AND 3 6 2. SUGGESTED
ALTERNATIVE CONVENTIONS FOR PROANTHO- CYANIDINS AND FLAVAN-3-OLS 6 A.
ENT SYSTEM FOR MIRROR IMAGE ISOMERS 6 B. A,P DESIGNATION FOR
HYDROXYLATION PATTERNS AND INTERFLAVANOID LINKAGES 7 3. 2,3-TRANS AND
2,3-CIS ISOMERS 7 4. EIZ CONVENTION FOR CIS AND TRANS ISOMER S OF PRENYL
AND ACYL GROUPS 8 5. SUGAR STEREOCHEMISTRY 8 II. NOMENCLATURE 9 III.
MAJOR GROUPS AND OVERALL PATHWAYS 9 IV. CONCLUSION 10 REFERENCES : 12
CHAPTER 2 ORIGIN OF PHENYLPROPANOID (C 6 -C 3 ) AND ACETATE UNITS 15 I.
INTRODUCTION 15 II. ORIGIN OF 4-COUMAROYL-COA 15 A. SHIKIMATE/AEROGENATE
PATHWAY 15 B. PHENYLPROPANOID PATHWAY 16 1. PHENYLALANINE AMMONIA-LYASE
(PAL) 16 2. CINNAMATE-4-HYDROXYLASE 18 3. 4-COUMARATE:COA LIGASE 18 III.
ORIGIN OF MALONYL-COA:ACETYL-COA CARBOXYLASE 18 IV. CONCLUSION 19
REFERENCES 20 CHAPTER 3 CHALCONE SYNTHASE AND CHALCONE ISOMERASE:
FLAVANONE SYNTHASE 23 I. INTRODUCTION 23 II. CHALCONE SYNTHASE 23 A.
ENZYMOLOGY 23 1. SYNTHESIS OF 6 -HYDROXYCHALCONE FOR THE
5-HYDROXYFLAVANONE PATHWAY 23 2. SYNTHESIS OF 6 -DEOXYCHALCONE FOR THE
5-DEOXYFLAVANONE PATHWAY 28 B. GENETIC CONTROL OF CHALCONE SYNTHASE 28
III. CHALCONE ISOMERASE 31 A. ENZYMOLOGY 31 1. 5-HYDROXY PATHWAY VIA
2 ,4,4 ,6 -TETRAHY- DROXYCHALCONE TO (2S ( + )-NARINGENIN 31 2. 5-DEOXY
PATHWAY VIA 2 ,4,4 -TRIHYDROXY- CHALCONE (ISOLIQUIRITIGENIN) TO
(25)-LIQUIRITIGENIN 32 B. GENETIC CONTROL 33 IV. CONCLUSION 34
REFERENCES 34 CHAPTER 4 BIOSYNTHESIS OF FLAVANONES AND
3-HYDROXYFLAVANONES (DIHYDROFLAVONOLS): THE GRID PATTERN OF BASIC
HYDROXYLATIONS OF THE B- AND C-RINGS 39 I. INTRODUCTION 39 II.
HYDROXYLASES OF RINGS AND B AND C 40 A. HYDROXYLATION AT THE 3 POSITION
IN RING B: 3 -HYDROXYLASE , 40 B. HYDROXYLATION AT THE 3 ,5 POSITIONS
IN RING B: VR 3 ,5 -HYDROXYLASE . 42 C. HYDROXYLATION AT THE 3 POSITION
IN RING C: FLAVANONE-3-HYDROXYLASE 42 D. SUMMARY OF GENETIC CONTROL OF
HYDROXYLATION PATTERNS IN PETUNIA AT THE 3,3 AND 3 ,5 POSITIONS 43
III. ACCUMULATION OF GRID PRECURSORS AS GLYCOSIDES 43 IV. CONCLUSION
43 REFERENCES 44 CHAPTER 5 FLAVONE AND FLAVONOL PATHWAYS 47 I.
INTRODUCTION 47 A. RECENT REVIEWS 47 B. DISTRIBUTION BETWEEN TAXONOMIC
GROUPS 47 C. SITE OF SYNTHESIS AND OF ACCUMULATION 47 II. CHEMISTRY 47
A. HYDROXYLATION PATTERNS 47 B. GLYCOSYL, METHYL, AND ACYL SUBSTITUTIONS
48 III. BIOSYNTHESIS 51 A. FEEDING AND ISOTOPIC TRACER DATA 51 B.
CELL-FREE ENZYMOLOGY 51 1. GENERAL 51 2. FLAVONE SYNTHASE 1 52 3.
FLAVONE SYNTHASE II 52 4. FLAVONOL SYNTHASE 54 5. GLYCOSYLATION,
METHYLATION, AND ACYLATION 54 A. FLAVONES 54 B. FLAVONOLS 57 IV.
REGULATION OF BIOSYNTHETIC PATHWAY 58 A. PHOTOREGULATION 58 B.
PLEIOTROPIC EFFECTS OF GENES AFFECTING KAEMPFEROL TRIGLUCOSIDE 59 C.
NUTRIENT EFFECTS 59 V. CONCLUSION 59 REFERENCES 59 CHAPTER 6 PATHWAY TO
PROANTHOCYANIDINS (CONDENSED TANNINS), FLAVAN-3-OLS, AND UNSUBSTITUTED
FLAVANS 63 I. INTRODUCTION 63 A. RECENT GENERAL REVIEWS 63 B.
DISTRIBUTION AMONG TAXONOMIC GROUPS .63 C. NOMENCLATURE 63 II. CHEMISTRY
OF PROANTHOCYANIDINS, FLAVAN-3-OLS, AND FLAVANS 65 A. BASIC STRUCTURE OF
A-, B-, AND C-RINGS 65 B. STEREOCHEMISTRY (2R AND 25 CONFIGURATIONS) 68
C. OLIGOMERIC STRUCTURE: (4*»8) AND (4*»6) INTERFLAVONOID LINKAGES 70 D.
GLYCOSYLATION, PRENYLATION, METHYLATION, AND ESTERIFICATION : 72 E.
QUANTITATIVE ASSAYS 72 III. BIOSYNTHESIS 73 A. ISOTOPIC TRACER FEEDING
DATA 73 B. CELL-FREE ENZYMOLOGY 75 1. COMMON PATHWAY TO
3-HYDROXYFLAVANONES (DIHYDROFLAVONOLS) 75 2. THE 2,3-TRANS PATHWAY TO
FLAVAN-3-OLS AND UNSUBSTITUTED FLAVANS VIA NADPH- DEPENDENT REDUCTASES
77 A. REDUCTION OF 3-HYDROXYFLAVANONES TO 3,4-DIOLS 77 B. REDUCTION OF
2,3-TRANS 3,4-DIOLS TO THEIR RESPECTIVE FLAVAN-3-OLS, (+ )- CATECHIN AND
(+ )-GALLOCATECHIN 78 C. REDUCTION OF FLAVANONES TO FLAVAN-4-OLS:
APIFEROL AND LUTEOFEROL .. . 79 D. POSTULATED REDUCTION OF FLAVAN-4-OLS
TO FLAVANS 79 3. THE 2,3-CIS PATHWAY TO (* )-EPICATECHIN AND (*
)-EPIGALLOCATECHIN 80 4. THE CONDENSATION STEP TO PRODUCE DIMERS AND
HIGHER OLIGOMERS 82 5. ORIGIN OF THE RARE 2S CONFIGURATION OR ENT FORMS
OF FLAVAN-3-OLS AND PROANTHOCYANIDINS 83 IV. COMPARTMENTATION AND
REGULATION : 84 A. INTRACELLULAR LOCALIZATION: SITES OF SYNTHESIS AND
ACCUMULATION 84 B. REGULATION OF THE 2,3-TRANS AND THE 2,3-CIS PATHWAYS*
A SPECULATIVE MODEL 84 C. DEVELOPMENTAL PATTERNS AND THE RATIO OF
PROCYANIDIN TO PRODELPHINIDIN (PC:PD) 87 D. ENVIRONMENTAL EFFECTS 88 V.
SECONDARY CHANGES AND DEGRADATIVE PATHWAYS 89 VI. GENETICS OF
PROANTHOCYANIDIN BIOSYNTHESIS 90 VII. FUNCTION 90 A. POSSIBLE METABOLIC
FUNCTION IN PLANTS 90 B. CHEMICAL DEFENSE AGAINST MICROORGANISMS AND
HERBIVORES 91 VIII. CONCLUSION . ; 92 REFERENCES 93 CHAPTER 7
ANTHOCYANIDIN-ANTHOCYANIN PATHWAY 101 I. INTRODUCTION 101 II. CHEMISTRY
=.,... 102 A. RING MODIFICATIONS: A-, B-, AND C- OF THE AGLYCONES 102 B.
FLAVYLIUM STRUCTURE TRANSFORMATIONS AND COPIGMENTATION 102 C. GLYCOSYL-,
METHYL-, AND ACYL- GROUPS 104 III. BIOSYNTHESIS 104 A. ISOTOPIC TRACER
AND FEEDING DATA 104 B. CELL-FREE ENZYMOLOGY 105 1. STEPS IN COMMON WITH
OTHER FLAVONOID PATHWAYS 105 2. STEPS UNIQUE TO ANTHOCYANIN BIOSYNTHESIS
107 A. SYNTHESIS OF THE 3-HYDROXY-FLAVYLIUM NUCLEUS 107 B. SYNTHESIS OF
THE 3-DEOXY-FLAVYLIUM NUCLEUS 109 C. GLYCOSYLATION, ACYLATION, AND
METHYLATION STEPS 109 C. SITE OF SYNTHESIS AND OF ACCUMULATION: TISSUE
AND INTRACELLULAR LOCALIZATION 110 IV. REGULATION OF THE SYNTHETIC
PATHWAY 112 A. REGULATION VIA ENZYME COMPLEXES OF LINEAR SEQUENCES
ASSOCIATED WITH MEMBRANES 112 B. PHOTOREGULATION AND HORMONAL REGULATION
OF ANTHOCYANIN BIOSYNTHESIS 113 C. ACCUMULATION AFTER WOUNDING AND AFTER
FUNGAL INFECTION 115 V. DEGRADATIVE PATHWAYS 115 VI. GENETICS 116 A.
GENERAL COMMENTS 116 B. CONIFERS 116 C. ANGIOSPERM DICOTS 117 1.
ANTIRRHINUM MAJUS 117 2. CALLISTEPHUS CHINENSIS 117 3. GLYCINE MAX 11 7
4. MATTHIOLA INCANA 117 5. PETUNIA HYBRIDA 118 6. PISUM SATIVUM 121 7.
SILENE DIOICA 121 D. ANGIOSPERM MONOCOTS 121 1. ZEA MAYS 121 2. HORDEUM
VULGARE 125 3. SORGHUM VULGARE 125 VII. CONCLUSION 125 REFERENCES ; 126
CHAPTER 8 ISOFLAVONOID PATHWAYS 133 I. INTRODUCTION 133 A. RECENT
REVIEWS 133 B. DISTRIBUTION BETWEEN TAXONOMIC GROUPS 133 II. CHEMISTRY
133 A. RING MODIFICATIONS OF THE AGLYCONES 133 B. MAJOR CHEMICAL GROUPS
134 III. BIOSYNTHESIS 135 A. FEEDING AND ISOTOPIC TRACER DATA 135 B.
CELL-FREE ENZYMOLOGY 139 1. CHALCONE SYNTHASES AND ISOMERASES TO
FLAVANONES: THE COMMON PATHWAY TO ISOFLAVONOIDS 139 2. THE 5-HYDROXY
PATHWAY FROM FLAVANONES TO ISOFLAVONES AND ISOFLAVANONES 140 A.
ISOFLAVONE SYNTHASE I TO GENISTEIN VIA A 2,3-ARYL MIGRATION * THE FIRST
UNIQUE STEP 140 B. O-METHYLTRANSFERASES 141 C. 2 -HYDROXYLATION 142 D.
PRENYLATION 142 3. THE 5-DEOXY PATHWAY TO 5-DEOXY ISOFLAVANONES AND
PTEROCARPANS FROM A :- * FLAVANONE 142 A. ISOFLAVONE SYNTHASE II TO
DAIDZEIN 142 B. REDUCTION TO ISOFLAVANONES 143 C. METHYLATION AT THE 4
POSITION TO FORM FORMONONETIN 143 D. 3 -HYDROXYLATION, DEMETHYLATION,
AND OXIDATIVE RING CLOSURE 143 E. 2 -HYDROXYLATION, REDUCTION, AND
CYCLIZATION TO PTEROCARPANS AND 6 -HYDROXYLATION 143 F. PRENYLATION AND
CYCLIZATION OF THE PRENYL GROUP 146 G. GLYCOSYLATION AND MALONYLATION
146 H. TERMINAL O-METHYLATION STEP 146 C. SITE OF SYNTHESIS AND
ACCUMULATION 146 IV. REGULATION OF THE ISOFLAVONOID PATHWAY 147 A.
PHOTOREGULATION 147 B. EFFECTS OF MICROBIAL AND PLANT ELICITORS 148 1.
GENERAL ASPECTS 148 2. PISATIN AND MAACKIAIN SYNTHESIS IN PISUM SATIVUM
148 3. GLYCEOLLIN SYNTHESIS IN GLYCINE MAX 148 4. KIEVITONE AND
PHASEOLLIN SYNTHESIS IN PHASEOLUS VULGARIS 150 V. DEGRADATIVE PATHWAYS
151 VI. GENETICS 152 VII. FUNCTION 152 A. ANTIMICROBIAL AND
INSECT-FEEDING DETERRENT ACTIVITY 152 B. HOST-RECOGNITION SIGNALS 153 C.
USES SIGNIFICANT TO HUMANS 153 VIII. CONCLUSION 154 REFERENCES 154
CHAPTER 9 CHALCONES, DIHYDROCHALCONES, AND AURONES 159 I. CHALCONES 159
II. DIHYDROCHALCONES AND THEIR OXIDATION PRODUCTS: PHLORIDZIN AND
PHLORETIN 161 III. AURONES 161 IV. CONCLUSION 162 REFERENCES 163 CHAPTER
10 BIFLAVONOIDS 165 I. CHEMISTRY AND ANALYTICAL TECHNIQUES 165 II.
TAXONOMIC DISTRIBUTION 166 III. INTRACELLULAR SITE AND FUNCTIONAL ROLE
166 IV. METABOLISM 167 V. CONCLUSION 168 REFERENCES 168 CHAPTER 11
SECONDARY CHANGES: RECYCLING AND DEGRADATION OF FLAVONOIDS 171 I.
INTRODUCTION 171 II. SECONDARY CHANGES WITHIN PLANTS 171 A. RECYCLING OF
STORAGE GLYCOSIDES: ONE ASPECT OF TURNOVER 171 B. DEGRADATION 173 1.
OXIDATION TO AMORPHOUS POLYMERS : 173 2. PARTIAL DEGRADATION AND
CATABOLISM TO USABLE PRIMARY PRODUCTS 173 III. CHANGES IN ANIMALS 175
IV. CHANGES BY MICROORGANISMS : 175 V. CONCLUSION 176 REFERENCES 176
CHAPTER 12 COMPETITIVE PATHWAYS IN SECONDARY METABOLISM 179 I.
INTRODUCTION 179 II. PHENYLPROANOID PATHWAY: PHENYLPROPANOID ACIDS AND
ESTERS 179 III. LIGNIN AND LIGNANS 180 IV. STILBENES AND RELATED
COMPOUNDS 183 V. TERPENOIDS 186 VI. CONCLUSION 186 REFERENCES 187
CHAPTER 13 REGULATION 189 I. INTRODUCTION: LEVELS OF CONTROL 189 II.
PATHWAYS INDUCIBLE BY EXTERNAL FACTORS 191 A. PHOTOREGULATED PATHWAYS
191 B. STRESS-INDUCED FLAVONOID PATHWAYS 193 1. GENERAL ASPECTS 193 2.
WOUNDING AND ETHYLENE PRODUCTION 194 3. INTERACTIONS WITH OTHER
ORGANISMS: PATHOGENS AND HERBIVORES 194 4. OSMOTIC STRESS X 197 III.
CONSTITUTIVE PATHWAYS 197 IV. ENDOGENOUS REGULATION OF ENZYME ACTIVITY
198 A. INHIBITORS 198 B. REVERSIBLE ENZYME INACTIVATION 199 C. LEVEL OF
ENZYME DEGRADATION 199 D. HORMONAL REGULATION AND OTHER CHEMICAL
MESSENGERS 200 E. DEVELOPMENTAL AND UNKNOWN FACTORS CONTROLLING
PHENOTYPIC EXPRESSION 201 V. COMPARTMENTATION 202 A. INTRACELLULAR
LOCALIZATION OF FLAVONOID PATHWAY ENZYMES AND THEIR END PRODUCTS 202 B.
INTERTISSUE LOCALIZATION 205 C. TRANSPORT PROBLEMS WITHIN AND BETWEEN
CELLS 206 VI. REGULATION BY ORGANIZATION OF ENZYMES IN PATHWAYS 208 A.
RELATIONSHIPS BETWEEN PRIMARY AND SECONDARY METABOLISM 208 B. METABOLIC
GRIDS AND THEIR SIGNIFICANCE 209 C. LINEAR SEQUENCES OF CYTOSOLIC AND
MEMBRANE LOCALIZED ENZYMES .* 210 1. POLYMORPHISM OF FLAVONOID ENZYMES
210 2. SPECULATIONS ABOUT MULTIENZYME COMPLEXES AS AGGREGATES OR
MEMBRANE-ASSOCIATED SEQUENCES 210 VII. CONCLUSION 216 REFERENCES 216
CHAPTER 14 IMPACT OF METHODOLOGY ON FLAVONOID METABOLISM 225 I.
INTRODUCTION 225 II. BASIC ANALYTICAL TECHNIQUES 227 III. CELL CULTURE
229 A. COMPARISON WITH PRODUCTS OF ORIGINAL INTACT TISSUE 229 B.
VARIABILITY AND INSTABILITY: SOMATIC GENETICS 230 C. CASE HISTORIES IN
FLAVONOID METABOLISM 230 D. ADVANTAGES AND DISADVANTAGES OF TISSUE
CULTURE 231 IV. BIOCHEMICAL AND MOLECULAR GENETICS, MUTANTS, GENETIC
ENGINEERING, AND TRANSPOSABLE GENETIC ELEMENTS 232 V. CONCLUSION 234
REFERENCES 235 CHAPTER 15 METABOLIC AND EVOLUTIONARY ASPECTS OF THE
BASIC FUNCTION OF FLAVONOIDS :.... 239 I. FUNCTIONS 239 A. GENERAL
ASPECTS 239 B. INTERNAL REGULATORY AGENTS IN PLANTS 239 1. ANTIOXIDANTS,
INHIBITORS, AND ACTIVATORS 239 2. NUCLEIC ACID STRAND SCISSION AGENTS
240 3. POTENTIAL DEVELOPMENTAL SIGNALS 241 C. INTERACTION WITH EXTERNAL
AGENTS 241 1. PROTECTION AGAINST UV IRRADIATION 241 2. CHEMICAL DEFENSE
AGAINST HERBIVORES AND PATHOGENS 241 A. GENERAL ASPECTS 241 B.
CONSTITUTIVE DEFENSES 242 C. INDUCIBLE DEFENSES 243 3. CHEMICAL SIGNALS
AS ATTRACTANTS 244 A. POLLINATION AND SEED DISPERSAL : 244 B.
RECOGNITION SIGNALS: FRIEND VS. FOE 245 D. FATE OF DIETARY FLAVONOIDS IN
ANIMALS AND FLAVONOIDS OF MEDICAL INTEREST 247 II. DISTRIBUTION AND
EVOLUTIONARY ASPECTS 248 A. CONDENSATION PRODUCTS WITH FEWER THAN THREE
ACETATE UNITS INCORPORATED 248 B. CONDENSATION PRODUCTS WITH THREE
ACETATE UNITS INCORPORATED: C, 5 FLAVONOIDS 248 1. DISTRIBUTION IN
PREVASCULAR PLANTS 248 2. DISTRIBUTION IN VASCULAR PLANTS 249 3.
EVOLUTIONARY TRENDS 250 4. HYPOTHETICAL SUMMARY DIAGRAM 252 III.
CONCLUSION 254 REFERENCES 254 CHAPTER 16 GENERAL HISTORY OF STUDIES OF
FLAVONOID METABOLISM 261 I. PRE-1925 CONCEPTS 261 II. 1925 VIEW OF
ONSLOW AND OTHER SCIENTISTS: ORIGIN OF BIOCHEMICAL GENETICS OF
FLAVONOIDS 262 III. THE 1940 VIEW 263 IV. THE FLAVANOID FRAUD OF 1940 TO
1955 264 V. POST 1945: ERA OF RADIOACTIVE TRACER STUDIES AND CELL-FREE
ENZYMOLOGY 264 VI. CONCLUSION 267 REFERENCES 267 INDEX 269
|
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| id | DE-604.BV004157109 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T16:09:12Z |
| institution | BVB |
| isbn | 0849360854 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-002592731 |
| oclc_num | 20094225 |
| open_access_boolean | |
| owner | DE-12 DE-355 DE-BY-UBR DE-188 |
| owner_facet | DE-12 DE-355 DE-BY-UBR DE-188 |
| physical | 298 S. graph. Darst. |
| publishDate | 1990 |
| publishDateSearch | 1990 |
| publishDateSort | 1990 |
| publisher | CRC Press |
| record_format | marc |
| spelling | Stafford, Helen A. Verfasser aut Flavonoid metabolism author: Helen A. Stafford Boca Raton, Fla. CRC Press 1990 298 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Flavonoïdes - Métabolisme Flavonoids Metabolism Flavonoids Metabolism Regulation Flavonoide (DE-588)4154585-0 gnd rswk-swf Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Biosynthese (DE-588)4006902-3 gnd rswk-swf Flavonoide (DE-588)4154585-0 s Stoffwechsel (DE-588)4057699-1 s DE-604 Biosynthese (DE-588)4006902-3 s GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002592731&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Stafford, Helen A. Flavonoid metabolism Flavonoïdes - Métabolisme Flavonoids Metabolism Flavonoids Metabolism Regulation Flavonoide (DE-588)4154585-0 gnd Stoffwechsel (DE-588)4057699-1 gnd Biosynthese (DE-588)4006902-3 gnd |
| subject_GND | (DE-588)4154585-0 (DE-588)4057699-1 (DE-588)4006902-3 |
| title | Flavonoid metabolism |
| title_auth | Flavonoid metabolism |
| title_exact_search | Flavonoid metabolism |
| title_full | Flavonoid metabolism author: Helen A. Stafford |
| title_fullStr | Flavonoid metabolism author: Helen A. Stafford |
| title_full_unstemmed | Flavonoid metabolism author: Helen A. Stafford |
| title_short | Flavonoid metabolism |
| title_sort | flavonoid metabolism |
| topic | Flavonoïdes - Métabolisme Flavonoids Metabolism Flavonoids Metabolism Regulation Flavonoide (DE-588)4154585-0 gnd Stoffwechsel (DE-588)4057699-1 gnd Biosynthese (DE-588)4006902-3 gnd |
| topic_facet | Flavonoïdes - Métabolisme Flavonoids Metabolism Flavonoids Metabolism Regulation Flavonoide Stoffwechsel Biosynthese |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002592731&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT staffordhelena flavonoidmetabolism |