Biochemistry of cell walls and membranes in fungi:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin u.a.
Springer
1990
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 327 S. Ill., graph. Darst. |
| ISBN: | 3540504370 0387504370 |
Internformat
MARC
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| 245 | 1 | 0 | |a Biochemistry of cell walls and membranes in fungi |c P. J. Kuhn ... (eds.) |
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Datensatz im Suchindex
| _version_ | 1804116861437083648 |
|---|---|
| adam_text | P J Kuhn APJ Trinci M J Jung
M W Goosey L G Copping (Eds )
biochemistry
of Cell Walls
and Membranes
in Fungi
With 88 Figures and 46 Tables
Springer-Veriag Berlin Heidelberg New York
London Paris Tokyo Hong Kong
Table of Contents
Chapter 1 Cell Walls and Membranes in Fungi -
An Introduction
P J KUHN and APJ TRINCI 1
References 4
Chapter 2 Fungal Cell Walls - A Review
J F PEBERDY 5
1 Introduction 5
2 The Chemistry and Architecture of the Fungal Cell
Wall 6
3 Synthesis of Cell Wall Polymers 9
4 Stability of the Cell Wall 11
5 Wall Formation During Protoplast Regeneration 12
6 Genetics and the Fungal Wall 13
7 The Cell Wall as a Target 16
8 The Cell Wall as an Interactive Surface 18
9 The Protective Role of the Cell Wall 21
10 Cell Wall Enzymes, Wall Porosity and Enzyme
Secretion 22
11 Concluding Statement 23
References 24
Chapter 3 Chitin Synthesis in Yeast
(Saccharomyces cerevisiae)
E CABIB, S J SILVERMAN, A SBURLATI, and
M L SLATER 31
1 Introduction 31
2 Zymogen Nature of Chitin Synthetase 31
3 Intracellular Distribution of Chitin Synthetase 32
4 Cloning of a Chitin Synthetase Structural Gene 32
5 A New Chitin Synthetase 34
6 Cloning of the Chitin Synthetase 2 Structural Gene 35
VIII Table of Contents
7 Requirement of Chitin Synthetase 2 for Cell Division 37
8 Chitin Synthetase 1-A Repair Enzyme? 38
9 The Present Status of Chitin Synthesis in Yeast 39
References 40
Chapter 4 A Novel Computer Model for Generating
Cell Shape: Application to Fungal Morphogenesis
S BARTNICKI-GARCIA, F HERGERT, and G GIERZ 43
1 Introduction 43
2 Current Concepts of Wall Growth in Fungi 43
3 A Model of Wall Growth Based on Vesicles 44
4 Computer Simulation of Morphogenesis 45
5 Mathematical Model for Hyphal Growth 48
6 Relationship of Spitzenkorper to VSC 51
7 The VSC Concept and Mechanisms for VSC
Displacement 51
8 Simulations of Morphogenetic Processes in Fungi 53
9 Limitations 56
10 Discussion and Conclusions 57
References 58
Chapter 5 Inhibition of Chitin Metabolism
G W GOODAY 61
1 Chitin Metabolism as a Target for Antifungal Agents 61
2 Chitin Synthase 61
3 Glutamine-Fructose-6-P-Aminotransferase 69
4 Chitinase • 70
5 Conclusions 74
References 74
Chapter 6 Wall Structure, Wall Growth, and Fungal Cell
Morphogenesis
JGH WESSELS, P C MOL, J H SIETSMA, and
C A VERMEULEN 81
1 Introduction 81
2 Alkali-Insoluble /?-Glucan in the Mature Wall Forms
Part of a Glucosaminoglycan-Glucan Complex 82
3 Secondary Structures in the Glucosaminoglycan-
Glucan Wall Complex 84
Table of Contents IX
4 Apical Biosynthesis and Morphogenesis of the
Hyphal Wall 86
5 Mycelium-Yeast Transitions 90
6 Diffuse Extension of Hyphal Walls 91
7 Conclusions 93
References 93
Chapter 7 Cellulose and /7-Glucan Synthesis in Saprolegnia
M FEVRE, V GIRARD, and P NODET 97
1 Introduction 97
2 Synthesis and Deposition of Cell Wall Glucans in
Saprolegnia hyphae 98
3 Cellulose Synthesis and Hyphal Morphogenesis 99
4 /?-Glucan Synthases from Saprolegnia 100
5 Purification of Glucan Synthases from Saprolegnia 103
6 Conclusions 105
References 105
Chapter 8 Synthesis and Function of Glycosylated Proteins in
Saccharomyces cerevisiae
W TANNER 109
1 Introduction 109
2 Biosynthetic Pathways 110
3 Functional Aspects 112
4 Summary 115
References 116
Chapter 9 Lipids in the Structure and Function of
Fungal Membranes
DM LOSEL 119
1 Introduction 119
2 The Membrane System 119
3 Membrane Structure 122
4 Membrane Composition 124
5 Functions of Membrane Lipids 127
6 Influence of Environment, Nutrition,
and Development on Membrane Composition
and Function 129
7 Conclusions 131
References 132
X Table of Contents
Chapter 10 Importance and Role of Sterols in Fungal
Membranes
H VANDEN BOSSCHE 135
1 Introduction 135
2 Ergosterol: Does It Meet the Requirements of
Fungal Membranes? 141
3 What Are the Consequences for the Cell to
Synthesize Alkylated Sterols? 150
4 Why Ergosterol Instead of Cholesterol? 152
References 153
Chapter 11 HMG-CoA to Isopentenyl Pyrophosphate -
Enzymology and Inhibition
R H ABELES 159
1 Hydroxymethylglutaryl-Coenzyme A (HMG-CoA)
Reductase 159
2 Isopentenyl Pyrophosphate Isomerase (IPPI) 162
3 Inhibition of Mevalonate-5-Pyrophosphate
Decarboxylase 163
References 166
Chapter 12 Isopentenyl Diphosphate to Squalene -
Enzymology and Inhibition
C D POULTER 169
1 Introduction 169
2 Isopentenyl Diphosphate: Dimethylallyl Diphosphate
Isomerase 171
3 Farnesyl Diphosphate Synthetase 177
4 Squalene Synthetase 181
5 Conclusions 186
References 186
Chapter 13 Squalene Epoxidase - Enzymology and
Inhibition
N S RYDER 189
1 Introduction 189
2 Enzymology 191
3 Squalene Epoxidase Inhibitors 194
4 Squalene Epoxidase Inhibitors as Antifungal
Agents 199
References 200
Table of Contents XI
Chapter 14 Inhibition of Sterol Biosynthesis in Higher Plants
by Analogues of High Energy Carbocationic
Intermediates
A RAHIER, M TATON, P BENVENISTE 205
1 Introduction 205
2 Inhibition of Phytosterol Biosynthesis by
Carbocationic HEI and Transition State Analogues 211
3 Conclusions 219
References 220
Chapter 15 Lanosterol to Ergosterol - Enzymology,
Inhibition and Genetics
S L KELLY, S KENNA, HFJ BLIGH, P F WATSON,
I STANSFIELD, S W ELLIS, and D E KELLY 223
1 Introduction 223
2 Antifungal Compounds and Their Activities 225
3 Fungal Cytochrome P-450 232
4 Conclusions and Implications for the Discovery of
Novel Antifungal Agents 238
References 238
Chapter 16 Biosynthesis and Role of Phospholipids in Yeast
Membranes
J E HILL, C CHUNG, P MCGRAW, E SUMMERS,
and S A HENRY 245
1 Regulation of Phospholipid Synthesis in
S cerevisiae - A Review 245
2 Regulation of Phospholipid Synthesis in S pombe
- Introduction 252
3 Roles of Phospholipids in S cerevisiae and
S pombe 257
References 259
Chapter 17 Inhibitors of Phospholipid Biosynthesis
G D ROBSON, M WlEBE, P J KUHN,
and APJ TRINCI 261
1 Introduction 261
2 Phospholipid Structure and Biosynthesis 262
3 Inhibitors of Phospholipid Biosynthesis 265
4 Validamycin and Edifenphos as Paramorphogens 276
References 277
XII Table of Contents
Chapter 18 Transduction of the Calcium Signal with Special
Reference to Ca2+-Induced Conidiation in
Penicillium notatum
D PITT and A KAILE 283
1 Introduction 283
2 Regulation of Intracellular Calcium 283
3 Calcium as an Intracellular Regulator 285
4 The Role of Calcium in Fungi 288
5 Ca2+ , Signal Transduction and Morphogenesis in
Fungi 288
6 Ca2+ and Signal Transduction in Penicillium
notatum 289
7 Concluding Comments 295
References 296
Chapter 19 Structure and Function of Fungal Plasma-
Membrane ATPases
C L SLAYMAN, P KAMINSKI, and D STETSON 299
1 Introduction 299
2 Membrane Appearance of the Plasma Membrane
(PM) ATPase 299
3 Functional Properties of the Proton Pump 301
4 Chemistry of the Enzyme 304
5 Primary Structure and Predictions 306
6 Models for Proton Pumping 310
7 Current Directions 314
References 315
Subject Index 317
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| id | DE-604.BV002438992 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T15:45:14Z |
| institution | BVB |
| isbn | 3540504370 0387504370 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-001581998 |
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| publisher | Springer |
| record_format | marc |
| spelling | Biochemistry of cell walls and membranes in fungi P. J. Kuhn ... (eds.) Berlin u.a. Springer 1990 XII, 327 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Biochemie gtt Celwanden gtt Champignons - Cytochimie Champignons - Membranes Fungi gtt Membranen gtt Fungal cell walls Fungal membranes Fungi Cytochemistry Pilze (DE-588)4046076-9 gnd rswk-swf Membran (DE-588)4038571-1 gnd rswk-swf Biomembran (DE-588)4006884-5 gnd rswk-swf Zellwand (DE-588)4190675-5 gnd rswk-swf Biochemie (DE-588)4006777-4 gnd rswk-swf Plasmamembran (DE-588)4067550-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Pilze (DE-588)4046076-9 s Zellwand (DE-588)4190675-5 s Biochemie (DE-588)4006777-4 s DE-604 Plasmamembran (DE-588)4067550-6 s Biomembran (DE-588)4006884-5 s Membran (DE-588)4038571-1 s Kuhn, Paul J. Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001581998&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Biochemistry of cell walls and membranes in fungi Biochemie gtt Celwanden gtt Champignons - Cytochimie Champignons - Membranes Fungi gtt Membranen gtt Fungal cell walls Fungal membranes Fungi Cytochemistry Pilze (DE-588)4046076-9 gnd Membran (DE-588)4038571-1 gnd Biomembran (DE-588)4006884-5 gnd Zellwand (DE-588)4190675-5 gnd Biochemie (DE-588)4006777-4 gnd Plasmamembran (DE-588)4067550-6 gnd |
| subject_GND | (DE-588)4046076-9 (DE-588)4038571-1 (DE-588)4006884-5 (DE-588)4190675-5 (DE-588)4006777-4 (DE-588)4067550-6 (DE-588)4143413-4 |
| title | Biochemistry of cell walls and membranes in fungi |
| title_auth | Biochemistry of cell walls and membranes in fungi |
| title_exact_search | Biochemistry of cell walls and membranes in fungi |
| title_full | Biochemistry of cell walls and membranes in fungi P. J. Kuhn ... (eds.) |
| title_fullStr | Biochemistry of cell walls and membranes in fungi P. J. Kuhn ... (eds.) |
| title_full_unstemmed | Biochemistry of cell walls and membranes in fungi P. J. Kuhn ... (eds.) |
| title_short | Biochemistry of cell walls and membranes in fungi |
| title_sort | biochemistry of cell walls and membranes in fungi |
| topic | Biochemie gtt Celwanden gtt Champignons - Cytochimie Champignons - Membranes Fungi gtt Membranen gtt Fungal cell walls Fungal membranes Fungi Cytochemistry Pilze (DE-588)4046076-9 gnd Membran (DE-588)4038571-1 gnd Biomembran (DE-588)4006884-5 gnd Zellwand (DE-588)4190675-5 gnd Biochemie (DE-588)4006777-4 gnd Plasmamembran (DE-588)4067550-6 gnd |
| topic_facet | Biochemie Celwanden Champignons - Cytochimie Champignons - Membranes Fungi Membranen Fungal cell walls Fungal membranes Fungi Cytochemistry Pilze Membran Biomembran Zellwand Plasmamembran Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001581998&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT kuhnpaulj biochemistryofcellwallsandmembranesinfungi |