The biological code:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
North-Holland Publ. Comp.
1969
|
| Schriftenreihe: | Frontiers of biology
12 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturverz. S. 288 - 329 |
| Beschreibung: | XIII, 360 S. graph. Darst. |
Internformat
MARC
| LEADER | 00000nam a2200000 cb4500 | ||
|---|---|---|---|
| 001 | BV002285421 | ||
| 003 | DE-604 | ||
| 005 | 20120621 | ||
| 007 | t | ||
| 008 | 890928s1969 d||| |||| 00||| eng d | ||
| 035 | |a (OCoLC)10861 | ||
| 035 | |a (DE-599)BVBBV002285421 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-12 |a DE-355 |a DE-20 |a DE-83 |a DE-188 |a DE-11 | ||
| 050 | 0 | |a QH431 | |
| 082 | 0 | |a 575.1 | |
| 082 | 0 | |a 574.19296 |2 18 | |
| 084 | |a WD 5300 |0 (DE-625)148199: |2 rvk | ||
| 100 | 1 | |a Yčas, Martynas |d 1885-1941 |e Verfasser |0 (DE-588)136222269 |4 aut | |
| 245 | 1 | 0 | |a The biological code |c M. Yčas |
| 264 | 1 | |a Amsterdam [u.a.] |b North-Holland Publ. Comp. |c 1969 | |
| 300 | |a XIII, 360 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Frontiers of biology |v 12 | |
| 500 | |a Literaturverz. S. 288 - 329 | ||
| 650 | 4 | |a Code génétique | |
| 650 | 4 | |a Génétique | |
| 650 | 7 | |a Nucleïnezuren |2 gtt | |
| 650 | 4 | |a Amino Acid Oxidoreductases | |
| 650 | 4 | |a Genetic Code | |
| 650 | 4 | |a Genetic code | |
| 830 | 0 | |a Frontiers of biology |v 12 |w (DE-604)BV001889020 |9 12 | |
| 856 | 4 | 2 | |m HEBIS Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001502031&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 940 | 1 | |q TUB-nveb | |
| 940 | 1 | |q HUB-ZB011201206 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-001502031 | ||
| 980 | 4 | |a (DE-12)AK24510627 | |
Datensatz im Suchindex
| _version_ | 1804116744857452544 |
|---|---|
| adam_text | THE
BIOLOGICAL
CODE
M YCAS
Department of Microbiology, College of Medicine,
State University of New York, Syracuse, New York
t
NORTH-HOLLAND PUBLISHING COMPANY - AMSTERDAM • LONDON
WILEY INTERSCIENCE DIVISION
JOHN WILEY amp; SONS, INC - NEW YORK
Contents
EDITORS PREFACE vn
PREFACE IX
Chapter 1 Introduction 1
1 1 Terms and definitions 2
111 Nucleic acids 2
112 Proteins 3
113 Reading 1
114 Coding terms 10
115 The nature of the code 11
Chapter 2 History of the coding problem 13
2 1 The early background 13
2 2 Early attempts to crack the code 21
Chapter 3^ In vivo studies of the code 36
3 1 Is the code colinear? 37
3 2 Is the code overlapping? 42
3 3 What is the coding ratio and codon length ? 48
3 4 Is the code degenerate? 58
341 Large variations in the composition of DNA 58
342 Reading frame shifts 60
343 Nitrite-induced mutations 61
344 Amino acid replacements 63
Chapter 4 The transfer of information from DNA 67
4 1 Ribosomal RNA 69
4 2 Messenger RNA 73
4 3 Are both strands of DNA read ? 82
Chapter 5 The cell-free system 95
5 1 Decoding using random copolymers 98
511j Uracil-rich codes 98
XII Contents
512 Some difficulties and criticisms 103
513 The sequence within codons 107
514 Codons without U Ill
515 The coding ratio 118
516 The nature of degeneracy 120
5 2 Binding by polymers of defined sequence 125
521 tRNA binding in the presence of trinucleotides 125
522 The adapting system 133
5 3 Peptide synthesis using polymers of defined sequence 135
5 4 The dictionary 140
Chapter 6 In vivo confirmation and ambiguity 144
6 1 Degeneracy and DNA composition 145
6 2 Amino acid replacements 151
621 Tobacco mosaic virus 153
622 Replacements in E coli 159
623 Replacements in human hemoglobin 161
6 3 Intracodon recombination 164
6 4 Decoding from reading frame shifts 166
6 5 The reading of natural messengers in vitro 170
6 6 Ambiguity 171
661 Organic solvents 173
662 Variations in/;H 174
663 Variations in temperature 174
664 Magnesium and other cations 174
665 Streptomycin 174
666 The site producing miscoding 175
6 7 iJliscoding by streptomycin and the ribosomes 176
6 8 Misreading in vivo 179
Chapter 7 The direction of reading and N-terminal punctuation 184
7 1 Mutual orientation of polymers 185
711 Orientation of RNA with respect 10 DNA 185
712 Orientation of protein with respect to RNA 185
7 2 Direction of assembly 190
721 Direction of assembly of RNA 190
722 Assembly of protein 191
7 3 Punctuation of transcription 193
7 4 N-terminal punctuation 195
Chapter 8 C-terminal punctuation, suppression and transfer RNA 208
8 1 The identity of nonsense codons 208
811 Genetic demonstration of nonsense 208
812 Genetic classification of nonsense 211
813 Base sequence of nonsense codons 213
Contents xm
8 2 Chain termination 221
821 Chain termination in vivo 221
822 Chain termination in vitro 222
823 The mechanism of chain termination 224
824 The molecular effect of suppression 225
825 Are nonsense codons C-terminal punctuation ? 227
8 3 Transfer RNA 230
831 The adaptor hypothesis 230
832 Specificity of tRNA 234
833 Specification of tRNA 235
834 Is there an anticodon ? 238
835 The specificity of tRNA 245
836 Suppression and tRNA 249
Chapter 9 Universality and the evolution of the code 254
9 1 Is the code universal ? 254
911 Synthetic polynucleotides 255
912 DNA in foreign hosts 258
913 Amino acid replacements 260
9 2 Evolution of DNA composition 261
9 3 The facts requiring explanation 269
9 4 Is an evolution of the code possible? 270
9 5 Theories of evolution 274
951 The mechanistic theory 275
952 Selection hypothesis 279
Chapter-JO Implications 284
BIBLIOGRAPHY 288
NAME INDEX 330
SUBJECT INDEX 342
|
| any_adam_object | 1 |
| author | Yčas, Martynas 1885-1941 |
| author_GND | (DE-588)136222269 |
| author_facet | Yčas, Martynas 1885-1941 |
| author_role | aut |
| author_sort | Yčas, Martynas 1885-1941 |
| author_variant | m y my |
| building | Verbundindex |
| bvnumber | BV002285421 |
| callnumber-first | Q - Science |
| callnumber-label | QH431 |
| callnumber-raw | QH431 |
| callnumber-search | QH431 |
| callnumber-sort | QH 3431 |
| callnumber-subject | QH - Natural History and Biology |
| classification_rvk | WD 5300 |
| ctrlnum | (OCoLC)10861 (DE-599)BVBBV002285421 |
| dewey-full | 575.1 574.19296 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 575 - Specific parts of & systems in plants 574 - [Unassigned] |
| dewey-raw | 575.1 574.19296 |
| dewey-search | 575.1 574.19296 |
| dewey-sort | 3575.1 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01537nam a2200445 cb4500</leader><controlfield tag="001">BV002285421</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20120621 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">890928s1969 d||| |||| 00||| eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)10861</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV002285421</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-12</subfield><subfield code="a">DE-355</subfield><subfield code="a">DE-20</subfield><subfield code="a">DE-83</subfield><subfield code="a">DE-188</subfield><subfield code="a">DE-11</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QH431</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">575.1</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">574.19296</subfield><subfield code="2">18</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WD 5300</subfield><subfield code="0">(DE-625)148199:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Yčas, Martynas</subfield><subfield code="d">1885-1941</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)136222269</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">The biological code</subfield><subfield code="c">M. Yčas</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Amsterdam [u.a.]</subfield><subfield code="b">North-Holland Publ. Comp.</subfield><subfield code="c">1969</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XIII, 360 S.</subfield><subfield code="b">graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Frontiers of biology</subfield><subfield code="v">12</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Literaturverz. S. 288 - 329</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Code génétique</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Génétique</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Nucleïnezuren</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Amino Acid Oxidoreductases</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genetic Code</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genetic code</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Frontiers of biology</subfield><subfield code="v">12</subfield><subfield code="w">(DE-604)BV001889020</subfield><subfield code="9">12</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HEBIS Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001502031&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">TUB-nveb</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">HUB-ZB011201206</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-001502031</subfield></datafield><datafield tag="980" ind1="4" ind2=" "><subfield code="a">(DE-12)AK24510627</subfield></datafield></record></collection> |
| id | DE-604.BV002285421 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T15:43:23Z |
| institution | BVB |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-001502031 |
| oclc_num | 10861 |
| open_access_boolean | |
| owner | DE-12 DE-355 DE-BY-UBR DE-20 DE-83 DE-188 DE-11 |
| owner_facet | DE-12 DE-355 DE-BY-UBR DE-20 DE-83 DE-188 DE-11 |
| physical | XIII, 360 S. graph. Darst. |
| psigel | TUB-nveb HUB-ZB011201206 |
| publishDate | 1969 |
| publishDateSearch | 1969 |
| publishDateSort | 1969 |
| publisher | North-Holland Publ. Comp. |
| record_format | marc |
| series | Frontiers of biology |
| series2 | Frontiers of biology |
| spelling | Yčas, Martynas 1885-1941 Verfasser (DE-588)136222269 aut The biological code M. Yčas Amsterdam [u.a.] North-Holland Publ. Comp. 1969 XIII, 360 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Frontiers of biology 12 Literaturverz. S. 288 - 329 Code génétique Génétique Nucleïnezuren gtt Amino Acid Oxidoreductases Genetic Code Genetic code Frontiers of biology 12 (DE-604)BV001889020 12 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001502031&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Yčas, Martynas 1885-1941 The biological code Frontiers of biology Code génétique Génétique Nucleïnezuren gtt Amino Acid Oxidoreductases Genetic Code Genetic code |
| title | The biological code |
| title_auth | The biological code |
| title_exact_search | The biological code |
| title_full | The biological code M. Yčas |
| title_fullStr | The biological code M. Yčas |
| title_full_unstemmed | The biological code M. Yčas |
| title_short | The biological code |
| title_sort | the biological code |
| topic | Code génétique Génétique Nucleïnezuren gtt Amino Acid Oxidoreductases Genetic Code Genetic code |
| topic_facet | Code génétique Génétique Nucleïnezuren Amino Acid Oxidoreductases Genetic Code Genetic code |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001502031&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV001889020 |
| work_keys_str_mv | AT ycasmartynas thebiologicalcode |