Structure and function of biomembranes: the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | Undetermined |
| Veröffentlicht: |
Tokyo
Japan Scientific Societies Pr.
1979
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 244 S. Ill., graph. Darst. |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1804116629167013888 |
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| adam_text | STRUCTURE AND FUNCTION
OF BIOMEMBRANES
The Proceedings of the First Congress of The Federation of Asian
and Oceanian Biochemists
edited by
KUNIO YAGI
Institute of Biochemistry, Faculty of Medicine
University of Nagoya, Nagoya {Japan)
JAPAN SCIENTIFIC SOCIETIES PRESS, Tokyo
CENTER FOR ACADEMIC PUBLICATIONS JAPAN, Tokyo
CONTENTS
Preface
MEMBRANE STRUCTURE
STUDIES ON LIPID-LIPID AND LIPID-PROTEIN INTERACTIONS WITH
PHYSICAL AND CHEMICAL METHODS
W STOFFEL 1
Sarcoplasmic Caz+-ATPase 3
Lipid-Protein Interactions in HDL 7
Photoaffinity Labeled Phospholipids as Chemical Probe for the Study of Mem-
brane Topography 14
CELL-LIPID INTERACTIONS
S NOJIMA, K INOUE, M NISHIJIMA, H UTSUMI, AND H HOMMA 1 7
THE PRINCIPLES OF LIGAND-PROTEIN INTERACTIONS AND THEIR
APPLICATION TO THE MECHANISM OF OXIDATIVE PHOSPHORYLATION
S JI 25
A General Molecular Model of Enzymic Catalysis 25
Free Energy Transfer from Chemical Reactions to Conformational Deformations
of Proteins 27
A Molecular Mechanism of Active Transport 30
A Molecular Mechanism of Oxidative Phosphorylation in Mitochondria 31
Theoretical Connections between the Proposed Mechanism of Oxidative Phos-
phorylation and Other Hypotheses in the Literature 34
Conclusion 36
CELL SURFACE AND BIOLOGICAL FUNCTION
REGULATION OF AMINO ACID AND HEXOSE TRANSPORT IN CULTURED
ANIMAL CELLS
C W CHRISTOPHER, D ULLREY, AND H M KALCKAR 39
Two Types of Relaxed Regulation of Transport Systems 39
Regulation of Amino Acid Transport 42
Relaxation of Regulation of Hexose Uptake and Transport 45
Other Culture Conditions 47
Other New Frontiers 48
vii
viii
REGULATORY EFFECT OF EXTRACELLULAR MOLECULES ON MATRIX
BIOSYNTHESIS BY CHONDROCYTES CULTURED IN VITRO
D A LOWTHER AND C J HANDLEY 51
Cartilage Matrix Formation and Organisation 51
The Effect of Extracellular Soluble Collagen and Proteoglycan on Matrix
Biosynthesis during Cartilage Growth 52
Structure of Proteoglycans 53
The Effect of Hyaluronic Acid or Proteoglycan on Proteoglycan Synthesis by
Chondrocytes in Culture 55
Do These Effects Depend on Intracellular Penetration of Hyaluronic Acid or
Proteoglycan Subunit? 57
The Mechanism of Inhibition Produced by Hyaluronic Acid and Proteoglycan
Synthesis by Chondrocytes 59
SOME BIOLOGICAL FUNCTIONS OF CELL SURFACE SUGARS
N SHARON 63
Lectins—Probes for Cell Surface Structure 64
Mitogenic Stimulation 67
Cell Surface Sugars on Different Lymphocyte Subpopulations 74
Receptors for Bacterial Attachment 78
BIOCHEMICAL BASIS OF SERUM GLYCOPROTEIN REGULATION BY
ENDOGENOUS HEPATIC LECTINS
G ASHWELL AND A MORELL 83
STRUCTURE AND FUNCTIONS OF MEMBRANE PROTEOGLYCANS
I YAMASHINA 89
Isolation and Characterization of Mucopolysaccharides from Ascites Hepatoma
Cells 90
Release of Complex Carbohydrates from Cells by Proteolysis 92
Role of Cell Surface Mucopolysaccharides 95
HUMAN HISTOCOMPATIBILITY ANTIGENS: ISOLATION AND STRUCTURE
J L STROMINGER, W FERGUSON, A FUKS, M GIPHART, J KAUFMAN, D MANN, H ORR,
P PARHAM, R ROBB, AND C TERHORST 99
Papain-solubilized HLA-A and -B Antigens 100
Detergent-solubilized HLA-A and -B Antigens 104
Structure of the HLA-D Gene Product 105
STUDIES OF MOLECULAR EVENTS IN AND ACROSS BIOLOGICAL
MEMBRANES
G K RADDA 109
Adrenaline Is Stored in Intracellular Vesicles 109
The ATPase Is a Proton Pump 110
The Chromaffin Granule Membrane 113
Looking Ahead 114
CONTENTS -IX
ASSEMBLY AND BIOGENESIS
BIOGENESIS OF ENDOPLASMIC RETICULUM MEMBRANE IN THE LIVER
CELL
T OMURA AND T HARANO 117
Mechanism of Formation of Endoplasmic Reticulum Membrane in the Liver
Cell 118
Asymmetric Distribution of Enzymes at the Step of Their Incorporation into the
Membrane of the Endoplasmic Reticulum 119
Role of Loosely-bound and Tightly-bound Ribosomes in the Biogenesis of
Endoplasmic Reticulum Membrane 122
Contribution of Endoplasmic Reticulum to the Biogenesis of Various Cell Or-
ganelles 123
MITOCHONDRIAL MUTANTS IN THE STUDY OF BIOGENESIS OF
MITOCHONDRIAL MEMBRANES
S MARZUKI, A ASTIN, AND A W LINNANE 127
General Considerations: Mitochondrial Mutants and Mitochondrial Genome of
Yeast 127
Mitochondrial Mutants in the Study of the Biogenesis of the OS-ATPase 131
Mitochondrial Mutants in the Study of the Biogenesis of the Cytochrome bc±
Complex 132
Concluding Remarks 137
ENERGY TRANSDUCTION
GENETIC AND BIOCHEMICAL STUDIES ON THE ATP-SYNTHESIZING
COMPLEX OF ESCHERICHIA COLI
F GIBSON 141
Dominance of unc+ Alleles 141
Construction of Plasmids Carrying Known Mutant unc Alleles 142
Test for Complementation between Different uncr Alleles 144
Identification of the Polypeptide Affected in Strains Carrying the uncD409
Allele 145
Organisation of the unc Gene Cluster 148
MITOCHONDRIAL HYDROGEN-ELECTRON TRANSFER AS A SOURCE OF
ENERGY: PROTEIN-PROTEIN AND PROTEIN-LIPID INTERACTIONS
T E KING 149
Components • 149
Complexes 151
Lipid Interaction with Succinate-Cytochrome c Reductase 158
Lipid Interaction with Cytochrome Oxidase 159
Concluding Remarks 162
STRUCTURE AND COMPOSITION OF THE MITOCHONDRIAL ENERGY
TRANSDUCTION SYSTEM
Y HATEFI, Y M GALANTE, L FRIGERI, AND D L STIGGALL 167
Composition of Complex V 171
Activities of Complex V 174
STUDIES OF PROTON TRANSPORT IN SUBMITOCHONDRIAL PARTICLES
AND RECONSTITUTED COMPLEXES OF THE RESPIRATORY CHAIN
P C HINKLE 185
Proton Transport by the Respiratory Chain in Submitochondrial Particles 185
Proton Transport by the ATPase 186
ATP Synthesis Driven by an Artificial Electrochemical Proton Gradient 1 8 6
Reconstitution of Complexes of the Mitochondrial Inner Membrane 187
Cytochrome Oxidase Vesicles 188
Coenzyme Q-Cytochrome c Reductase Vesicles 190
NADH-coenzyme Q Reductase Vesicles 190
Future Prospects 190
A MECHANISM OF UNCOUPLER-MEDIATED PROTON TRANSLOCATION IN
LIPOSOMAL MEMBRANE
Y ANRAKU 193
Chemical Properties of SF6847 194
Kinetics of Proton Uptake 194
Ternary Complex, VAL-K+-SF- 196
Spectroscopic Determination of Partition Constants 197
Ternary Complex in Phospholipids and in Hexane 199
Mechanism of Reaction 199
PHOSPHORYLATION OF MITOCHONDRIAL BOUND ADENINE NUCLEOTIDES
AND ITS RELATION TO OXIDATIVE PHOSPHORYLATION
T OZAWA 203
STRUCTURE AND FUNCTION OF MITOCHONDRIAL ATPASE F,
E C SLATER 211
PURIFIED PUMP, GATE, AND CHANNEL OF PROTON TRANSLOCATING
ATPASE
Y KAGAWA 219
Subunit Structure of Fo-F, (H+-ATPase) 220
Structure of Crystalline Fr 221
Reconstitution of ATPase Activity from Purified Subunits 223
Gate of Proton Translat ion 224
Channel of Proton Translocation 225
Function of the Reconstituted H+-ATPase Vesicles 228
Epilogue 229
CONTENTS XI
THE MECHANISM OF ENERGY TRANSDUCTION IN
PHOTOPHOSPHORYLATION
M AVRON : 233
Proton Uptake and Proton Gradient 233
Proton Gradients and ATP Formation 237
Proton Gradient and Reverse Electron Flow 238
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| spelling | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists Hrsg. von Kunio Yagi* Tokyo Japan Scientific Societies Pr. 1979 XI, 244 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Biomembran (DE-588)4006884-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1977 Nagoya gnd-content Biomembran (DE-588)4006884-5 s DE-604 Yagi, Kunio Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001427729&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists Biomembran (DE-588)4006884-5 gnd |
| subject_GND | (DE-588)4006884-5 (DE-588)1071861417 |
| title | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists |
| title_auth | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists |
| title_exact_search | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists |
| title_full | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists Hrsg. von Kunio Yagi* |
| title_fullStr | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists Hrsg. von Kunio Yagi* |
| title_full_unstemmed | Structure and function of biomembranes the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists Hrsg. von Kunio Yagi* |
| title_short | Structure and function of biomembranes |
| title_sort | structure and function of biomembranes the proceedings of the 1 congress of the federation of asian oceanian biochemists |
| title_sub | the proceedings of the 1. Congress of the Federation of Asian Ǒceanian Biochemists |
| topic | Biomembran (DE-588)4006884-5 gnd |
| topic_facet | Biomembran Konferenzschrift 1977 Nagoya |
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