Search and discovery: a tribute to Albert Szent-Györgyi
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York u.a.
Acad. Pr.
1977
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XXVIII, 344 S. Ill., graph. Darst. |
Internformat
MARC
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| 245 | 1 | 0 | |a Search and discovery |b a tribute to Albert Szent-Györgyi |c Hrsg. von Benjamin Kaminer* |
| 264 | 1 | |a New York u.a. |b Acad. Pr. |c 1977 | |
| 300 | |a XXVIII, 344 S. |b Ill., graph. Darst. | ||
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| 650 | 4 | |a Biochemistry | |
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Datensatz im Suchindex
| _version_ | 1804116488571846656 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
LIST OF CONTRIBUTORS XV
PREFACE XIX
ACKNOWLEDGMENTS XXI
SOME RECOLLECTIONS OF ALBERT SZENT-GYBRGYI JOHN T. EDSALL XXVII
METABOLISM
1 ERRORS, FALSE TRAILS, AND FAILURES IN RESEARCH HANS KREBS 3
ERRORS AND MISCONCEPTIONS IN THE WORK LEADING TO THE CONCEPT OF THE
TRICARBOXYLIC ACID CYCLE 7
FALSE INTERPRETATION OF ISOTOPE EXPERIMENTS RELATED TO THE TRICARBOXYLIC
ACID CYCLE 9
FALSE TRAILS CONCERNING GLYCOLYSIS 10
A FALSE TRAIL IN THE STUDY OF PROTEIN SYNTHESIS 11
ERRORS IN CLINICAL MEDICINE 12
SCIENTIFIC REVOLUTIONS 13
GENERAL REMARKS 14
REFERENCES 14
2 ON SOME UNUSUAL NUCLEOTIDE POLYPHOSPHATES FRITZ LIPMANN 17
CYCLIC AMP 18
GUANOSINE TETRA- AND PENTAPHOSPHATES 23
REFERENCES 30
VII
IMAGE 2
II CONTENTS
3 EKTOBIOLOGY, TRANSPORT OF NUTRIENTS, AND CHEMOTAXIS HERMAN M. KALCKAR
33
EKTOBIOLOGY AND SUGARS 33
TRANSPORT BIOLOGY AND CHEMOTAXIS 34
REGULATION OF TRANSPORT AND UPTAKE AND TUMOR BIOLOGY 37
REFERENCES 39
VITAMIN C AND HEALTH
4 ALBERT SZENT-GYORGYI AND VITAMIN C LINUS PAULING 43
THE OPTIMUM INTAKE OF VITAMIN C 45
THE COMMON COLD 46
VIRUSES AND VIRAL DISEASES 47
BACTERIA AND BACTERIAL DISEASES 48
VITAMIN C AND CARDIOVASCULAR DISEASE 49
VITAMIN C AND CANCER 51
CONCLUSION 52
REFERENCES 53
5 WHAT S AHEAD FOR MEDICAL RESEARCH AND HEALTH CARE? JOHN PLATT 55
MUSCLE
6 PAST AND PRESENT STUDIES ON THE INTERACTION OF ACTIN AND MYOSIN H. E.
HUXLEY 63
SOME CURRENT WORK ON ACTOMYOSIN 69
REFERENCES 74
7 TROPONIN AND ITS FUNCTION SETSURO EBASHI 11
INTRODUCTION 77
THE MECHANISM OF TROPONIN ACTION 80
TROPONIN AND TROPOMYOSIN IN SMOOTH MUSCLE 84
CONCLUDING REMARKS 87
REFERENCES 87
IMAGE 3
CONTENTS IX
8 MOLECULAR MOVEMENTS AND CONFORMATIONAL CHANGES IN MUSCLE CONTRACTION
AND REGULATION ./. GERGELY 91
INTRODUCTION 92
INTERNAL MOVEMENTS IN MYOSIN 93
MOLECULAR CHANGES IN REGULATION 96
CONCLUSIONS 98
REFERENCES 98
9 HOW ACTIVE IS ACTIN? PROPAGATED CONFORMATIONAL CHANGES IN THE ACTIN
FILAMENT JOSEPH LOSCALZO, GEORGE H. REED, AND ANNEMARIE WEBER 99
TEXT 99
REFERENCES 106
10 MYOSIN-LINKED REGULATION OF MUSCLE CONTRACTION ANDREW G.
SZENT-GYB RGYI 107
PERSONAL REMARKS 107
GENERAL CONSIDERATIONS 108
COMPARISON OF THE TWO CONTROL SYSTEMS OF MUSCLES 109
PROPERTIES OF MYOSIN CONTROL 111
REFERENCES 115
11 FROM UTERINE ACTOMYOSIN TO PARTURITION ARPAD I. CSAPO 117
A STEP TOWARD QUANTITATIVE UTERINE PHYSIOLOGY 118
THE PROBLEM 118
A MODEL OF UTERINE FUNCTION 119
REGULATION 130
THE SEESAW THEORY 137
THE MAINTENANCE AND TERMINATION OF PREGNANCY 145
A PERSONAL NOTE 148
REFERENCES 148
12 FROM UTERINE ACTOMYOSIN TO UTERINE STEROID HORMONE RECEPTORS TAMAS
ERDOS 151
INTRODUCTION 151
THE EFFECT OF STRETCH ON MYOMETRIAL GROWTH AND FUNCTION 152
IMAGE 4
X CONTENTS
THE UTERINE ESTRADIOL RECEPTOR 153
PROGESTERONE AND PREGNANCY MAINTENANCE 154
WHAT IS IN THE BLACK BOX? 156
REFERENCES 158
13 EFFECTS OF HEAVY WATER ON MUSCLE BENJAMIN KAMINER 161
HEART MUSCLE 162
SMOOTH MUSCLE 167
STRIATED MUSCLE 169
REFERENCES 173
CROSS-UNKING AND COMPLEXES
14 BIOLOGICAL FUNCTIONS OF TRANSAMIDATING ENZYMES WHICH CROSS-LINK
PROTEINS LASZLO LORAND 177
ENZYME-TRIGGERED PROTEIN ASSOCIATIONS 177
, 2 IO-7-GLUTAMINE: E-LYSINE TRANSFERASE ENZYMES WHICH CROSS-LINK
PROTEINS 179
FIBRINOLIGASE GENERATION IN BLOOD PLASMA 181
CATALYSIS BY FIBRINOLIGASE 183
HYBRID SYSTEMS 186
CLINICAL ASPECTS OF FIBRIN STABILIZATION 187
CONCLUSION 191
REFERENCES 191
15 PHYSICAL PROPERTIES OF THE INNER HISTONES (H2A, H2B, H3, H4) IRVIN
ISENBERG 195
INTRODUCTION 195
THE PRIMARY SEQUENCES OF THE HISTONES 197
HISTONE REFOLDING 200
HISTONE AGGREGATION 204
HISTONE-HISTONE INTERACTIONS 206
HISTONE-HISTONE INTERACTIONS IN CHROMATIN 209
SUMMARY OF THE KNOWN PHYSICAL PROPERTIES OF THE INNER HISTONES (H2A,
H2B, H3, H4) 212
REFERENCES 214
IMAGE 5
CONTENTS XI
SUBMOLECULAR BIOLOGY
16 MOLECULAR DIMENSIONALITY IN RELATION TO PHENOMENOLOGY FROM THE ATOM
TO THE LIVING CELL MICHAEL KASHA 219
CORRELATION OF MOLECULAR DIMENSIONALITY WITH PHENOMENOLOGY 220 TYPICALLY
POLYATOMIC BEHAVIOR 220
ELECTRONIC PROCESSES IN MOLECULAR AGGREGATES 221
SIMULTANEOUS TRANSITIONS IN SINGLET MOLECULAR OXYGEN PAIRS 223 MOLECULAR
EXCITONS IN SMALL AGGREGATES 224
BIPROTONIC PHOTOAUTOMERISM AND WATER STRUCTURE 226
POTENTIAL MODEL OF THE SOLVENT CAGE 228
SUMMARY 229
REFERENCES . 230
17 BOUND WATER IN BIOLOGICAL SYSTEMS A QUANTUM-MECHANICAL INVESTIGATION
ALBERTE PULLMAN 231
INTRODUCTION 231
HYDRATION SITES AND BINDING ENERGIES 232
THE STRUCTURE OF BOUND WATER 234
CONCLUSIONS 248
REFERENCES 248
18 AN ASPECT OF SUBMOLECULAR BIOLOGY QUANTUM-MECHANICAL EXPLORATION OF
BIOMOLECULAR CONFORMATIONS-THE CASE OF PHOSPHOLIPIDS BERNARD PULLMAN 251
THEORETICAL APPROACH TO CONFORMATIONS OF BIOMOLECULES 252 THE
CONFORMATION OF PHOSPHOLIPIDS 254
CONCLUSIONS 267
REFERENCES 269
CELL GROWTH AND CANCER
19 RETICULOENDOTHELIAL CELLS IN MATRIX-INDUCED FIBROBLAST-TRANSFORMATION
OSSICLES CHARLES B. HUGGINS AND A. H. REDDI 273
MATERIALS AND METHODS 274
IMAGE 6
XII CONTENTS
RESULTS AND DISCUSSION 276
SUMMARY 278
REFERENCES 278
20 BIOCHEMICAL STRATEGY OF GENE EXPRESSION GEORGE WEBER 279
CONCEPTUAL BACKGROUND 280
MATERIALS AND METHODS 285
RESULTS AND DISCUSSION 286
PERSONAL COMMENTS 301
REFERENCES 301
21 A POSSIBLE ROLE OF TRANSGLUTAMINASE IN TUMOR GROWTH AND METASTASES K.
LAKI, G. CSAKO, S. T. YANCEY, AND E. F. WILSON 303
MATERIALS AND METHODS 304
RESULTS 305
DISCUSSION 310
REFERENCES 311
22 SOME PROBLEMS AND APPROACHES IN VIRAL AND CANCER CHEMOTHERAPY SEYMOUR
S. COHEN 313
EXPLOITATION OF VIRUS-INDUCED ENZYMES 315
INHIBITION OF DNA SYNTHESIS AND CELL TOXICITY 316
THE MODE OF ACTION OF 5-FLUOROURACIL 317
D-ARABINOSYL NUCLEOSIDES AS THERAPEUTIC AGENTS 318
ARAC AND TETRAHYDROURIDINE 319
THE MODES OF ACTION OF ARA NUCLEOSIDES 320
THE POTENTIATION OF ARAA BY A DEAMINASE INHIBITOR 321
THE POTENTIATION OF CORDYCEPIN 322
THE PENETRATION OF NUCLEOTIDES INTO CELLS 324
DISCUSSION 325
REFERENCES 327
23 ELECTRONIC BIOLOGY AND CANCER ALBERT SZENT-GYORGYI 329
OXYGEN AND DICARBONYLS 330
AMINES AND DICARBONYLS 332
IMAGE 7
CONTENTS XIII
THE A-0 TRANSFORMATION AND CANCER 334
REFERENCES 335
EPILOGUE
24 EPILOGUE
MICHAEL KASHA 339
INDEX 341
|
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| spelling | Search and discovery a tribute to Albert Szent-Györgyi Hrsg. von Benjamin Kaminer* New York u.a. Acad. Pr. 1977 XXVIII, 344 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Szent-Györgyi, Albert <1893-> Szent-Györgyi, Albert <1893-1986> Biochimie Bioquímica larpcal Biochemistry Biochemistry Congresses Biochemie (DE-588)4006777-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content (DE-588)4016928-5 Festschrift gnd-content (DE-588)1071861417 Konferenzschrift gnd-content Biochemie (DE-588)4006777-4 s DE-604 Kaminer, Benjamin Sonstige oth Szent-Györgyi, Albert 1893-1986 (DE-588)118799614 hnr SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001332773&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Search and discovery a tribute to Albert Szent-Györgyi Szent-Györgyi, Albert <1893-> Szent-Györgyi, Albert <1893-1986> Biochimie Bioquímica larpcal Biochemistry Biochemistry Congresses Biochemie (DE-588)4006777-4 gnd |
| subject_GND | (DE-588)4006777-4 (DE-588)4143413-4 (DE-588)4016928-5 (DE-588)1071861417 |
| title | Search and discovery a tribute to Albert Szent-Györgyi |
| title_auth | Search and discovery a tribute to Albert Szent-Györgyi |
| title_exact_search | Search and discovery a tribute to Albert Szent-Györgyi |
| title_full | Search and discovery a tribute to Albert Szent-Györgyi Hrsg. von Benjamin Kaminer* |
| title_fullStr | Search and discovery a tribute to Albert Szent-Györgyi Hrsg. von Benjamin Kaminer* |
| title_full_unstemmed | Search and discovery a tribute to Albert Szent-Györgyi Hrsg. von Benjamin Kaminer* |
| title_short | Search and discovery |
| title_sort | search and discovery a tribute to albert szent gyorgyi |
| title_sub | a tribute to Albert Szent-Györgyi |
| topic | Szent-Györgyi, Albert <1893-> Szent-Györgyi, Albert <1893-1986> Biochimie Bioquímica larpcal Biochemistry Biochemistry Congresses Biochemie (DE-588)4006777-4 gnd |
| topic_facet | Szent-Györgyi, Albert <1893-> Szent-Györgyi, Albert <1893-1986> Biochimie Bioquímica Biochemistry Biochemistry Congresses Biochemie Aufsatzsammlung Festschrift Konferenzschrift |
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